CN100349873C - 制备咪唑基化合物的新方法 - Google Patents
制备咪唑基化合物的新方法 Download PDFInfo
- Publication number
- CN100349873C CN100349873C CNB2003801035559A CN200380103555A CN100349873C CN 100349873 C CN100349873 C CN 100349873C CN B2003801035559 A CNB2003801035559 A CN B2003801035559A CN 200380103555 A CN200380103555 A CN 200380103555A CN 100349873 C CN100349873 C CN 100349873C
- Authority
- CN
- China
- Prior art keywords
- hydrogen
- alkyl
- compound
- general formula
- butanols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02079838 | 2002-11-18 | ||
EP02079838.5 | 2002-11-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1714082A CN1714082A (zh) | 2005-12-28 |
CN100349873C true CN100349873C (zh) | 2007-11-21 |
Family
ID=32319633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2003801035559A Expired - Fee Related CN100349873C (zh) | 2002-11-18 | 2003-11-17 | 制备咪唑基化合物的新方法 |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1565445B1 (no) |
JP (1) | JP4611026B2 (no) |
KR (1) | KR20050075026A (no) |
CN (1) | CN100349873C (no) |
AR (1) | AR041955A1 (no) |
AT (1) | ATE340783T1 (no) |
AU (1) | AU2003296762B2 (no) |
BR (1) | BR0316308A (no) |
CA (1) | CA2504614C (no) |
DE (1) | DE60308720T2 (no) |
DK (1) | DK1565445T3 (no) |
ES (1) | ES2273088T3 (no) |
HK (1) | HK1081188A1 (no) |
HR (1) | HRP20050376A2 (no) |
IL (1) | IL168258A (no) |
MX (1) | MXPA05005261A (no) |
NO (1) | NO330342B1 (no) |
PL (1) | PL376743A1 (no) |
PT (1) | PT1565445E (no) |
RU (1) | RU2314296C2 (no) |
SA (1) | SA03240414B1 (no) |
SI (1) | SI1565445T1 (no) |
UA (1) | UA79655C2 (no) |
WO (1) | WO2004046116A1 (no) |
ZA (1) | ZA200503425B (no) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0297651A1 (en) * | 1987-06-29 | 1989-01-04 | Duphar International Research B.V | Anellated indole derivatives |
-
2003
- 2003-11-13 AR ARP030104180A patent/AR041955A1/es unknown
- 2003-11-17 MX MXPA05005261A patent/MXPA05005261A/es active IP Right Grant
- 2003-11-17 BR BR0316308-3A patent/BR0316308A/pt active Pending
- 2003-11-17 PT PT03811396T patent/PT1565445E/pt unknown
- 2003-11-17 CN CNB2003801035559A patent/CN100349873C/zh not_active Expired - Fee Related
- 2003-11-17 AU AU2003296762A patent/AU2003296762B2/en not_active Ceased
- 2003-11-17 UA UAA200505941A patent/UA79655C2/uk unknown
- 2003-11-17 DE DE60308720T patent/DE60308720T2/de not_active Expired - Lifetime
- 2003-11-17 PL PL376743A patent/PL376743A1/pl not_active Application Discontinuation
- 2003-11-17 DK DK03811396T patent/DK1565445T3/da active
- 2003-11-17 ES ES03811396T patent/ES2273088T3/es not_active Expired - Lifetime
- 2003-11-17 EP EP03811396A patent/EP1565445B1/en not_active Expired - Lifetime
- 2003-11-17 WO PCT/EP2003/050841 patent/WO2004046116A1/en active IP Right Grant
- 2003-11-17 AT AT03811396T patent/ATE340783T1/de active
- 2003-11-17 JP JP2004552730A patent/JP4611026B2/ja not_active Expired - Fee Related
- 2003-11-17 SI SI200330519T patent/SI1565445T1/sl unknown
- 2003-11-17 KR KR1020057008864A patent/KR20050075026A/ko active IP Right Grant
- 2003-11-17 RU RU2005119155/04A patent/RU2314296C2/ru not_active IP Right Cessation
- 2003-11-17 CA CA2504614A patent/CA2504614C/en not_active Expired - Fee Related
- 2003-12-03 SA SA03240414A patent/SA03240414B1/ar unknown
-
2005
- 2005-04-27 IL IL168258A patent/IL168258A/en not_active IP Right Cessation
- 2005-04-28 ZA ZA200503425A patent/ZA200503425B/xx unknown
- 2005-04-28 HR HR20050376A patent/HRP20050376A2/xx not_active Application Discontinuation
- 2005-06-16 NO NO20052950A patent/NO330342B1/no not_active IP Right Cessation
-
2006
- 2006-01-26 HK HK06101176A patent/HK1081188A1/xx not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0297651A1 (en) * | 1987-06-29 | 1989-01-04 | Duphar International Research B.V | Anellated indole derivatives |
Non-Patent Citations (2)
Title |
---|
N-substituted tetrahydro 1 3 oxazines and oxazolidine s 1 anew version of the mannich reacti on involving amino cohols. A G KOREPIN ET AL.RUSSIAN CHEMICAL BULLETIN,Vol.50 No.1. 2001 * |
Synthetic routes to benz a nd naphthindenoquinolines. H ANTAKI.JOURNAL OF THE CHE MICAL SOCIETY,Vol.17. 1967 * |
Also Published As
Publication number | Publication date |
---|---|
NO20052950D0 (no) | 2005-06-16 |
DE60308720D1 (de) | 2006-11-09 |
JP2006512322A (ja) | 2006-04-13 |
RU2314296C2 (ru) | 2008-01-10 |
EP1565445B1 (en) | 2006-09-27 |
BR0316308A (pt) | 2005-09-27 |
PT1565445E (pt) | 2007-01-31 |
DE60308720T2 (de) | 2007-01-11 |
SA03240414B1 (ar) | 2006-12-05 |
IL168258A (en) | 2010-05-31 |
UA79655C2 (en) | 2007-07-10 |
AU2003296762B2 (en) | 2010-03-18 |
ES2273088T3 (es) | 2007-05-01 |
KR20050075026A (ko) | 2005-07-19 |
CN1714082A (zh) | 2005-12-28 |
NO330342B1 (no) | 2011-03-28 |
DK1565445T3 (da) | 2007-01-29 |
WO2004046116A1 (en) | 2004-06-03 |
HRP20050376A2 (en) | 2006-02-28 |
AR041955A1 (es) | 2005-06-01 |
SI1565445T1 (sl) | 2007-02-28 |
EP1565445A1 (en) | 2005-08-24 |
PL376743A1 (pl) | 2006-01-09 |
MXPA05005261A (es) | 2005-07-25 |
ZA200503425B (en) | 2007-02-28 |
HK1081188A1 (en) | 2006-05-12 |
NO20052950L (no) | 2005-08-15 |
ATE340783T1 (de) | 2006-10-15 |
CA2504614A1 (en) | 2004-06-03 |
CA2504614C (en) | 2010-09-28 |
JP4611026B2 (ja) | 2011-01-12 |
RU2005119155A (ru) | 2006-01-20 |
AU2003296762A1 (en) | 2004-06-15 |
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