CL2015003315A1 - Inhibidores de acc y usos de los mismos - Google Patents
Inhibidores de acc y usos de los mismosInfo
- Publication number
- CL2015003315A1 CL2015003315A1 CL2015003315A CL2015003315A CL2015003315A1 CL 2015003315 A1 CL2015003315 A1 CL 2015003315A1 CL 2015003315 A CL2015003315 A CL 2015003315A CL 2015003315 A CL2015003315 A CL 2015003315A CL 2015003315 A1 CL2015003315 A1 CL 2015003315A1
- Authority
- CL
- Chile
- Prior art keywords
- acc inhibitors
- heteroatomo
- heterocicles
- dislipidemia
- hyperlipidemia
- Prior art date
Links
- 229940121373 acetyl-coa carboxylase inhibitor Drugs 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pretreatment Of Seeds And Plants (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361821828P | 2013-05-10 | 2013-05-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2015003315A1 true CL2015003315A1 (es) | 2016-07-15 |
Family
ID=51867753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2015003315A CL2015003315A1 (es) | 2013-05-10 | 2015-11-10 | Inhibidores de acc y usos de los mismos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10208063B2 (enExample) |
| EP (1) | EP2994139B1 (enExample) |
| JP (1) | JP6434498B2 (enExample) |
| KR (1) | KR20160006762A (enExample) |
| CN (1) | CN105358154A (enExample) |
| AR (1) | AR096242A1 (enExample) |
| AU (1) | AU2014262638A1 (enExample) |
| BR (1) | BR112015028152A2 (enExample) |
| CA (1) | CA2911932A1 (enExample) |
| CL (1) | CL2015003315A1 (enExample) |
| EA (1) | EA030942B1 (enExample) |
| HK (2) | HK1221661A1 (enExample) |
| MX (1) | MX2015015422A (enExample) |
| WO (1) | WO2014182945A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA030958B1 (ru) | 2013-05-10 | 2018-10-31 | Джилид Аполло, Ллс | Ингибиторы акк и их применение |
| US9988399B2 (en) | 2013-05-10 | 2018-06-05 | Gilead Apollo, Llc | Bicyclic compounds as ACC inhibitors and uses thereof |
| EA201591962A1 (ru) | 2013-05-10 | 2016-06-30 | Нимбус Аполло, Инк. | Ингибиторы акк и их применение |
| JPWO2015056782A1 (ja) | 2013-10-17 | 2017-03-09 | 塩野義製薬株式会社 | 新規アルキレン誘導体 |
| JP6668253B2 (ja) * | 2014-11-26 | 2020-03-18 | 武田薬品工業株式会社 | 二環性化合物 |
| BR112017014341A2 (pt) | 2015-01-09 | 2018-03-27 | Gilead Apollo, Llc | método e sistema para tratamento, estabilização, ou redução da gravidade ou progressão de uma doença de fígado gorduroso não alcoólica, e, composição. |
| AR106472A1 (es) | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
| US20170166583A1 (en) | 2015-11-25 | 2017-06-15 | Gilead Apollo, Llc | Ester acc inhibitors and uses thereof |
| PT3380479T (pt) | 2015-11-25 | 2023-03-13 | Gilead Apollo Llc | Inhibidores de triazol acc e seus usos |
| US20170166582A1 (en) | 2015-11-25 | 2017-06-15 | Gilead Apollo, Llc | Pyrazole acc inhibitors and uses thereof |
| US20170166585A1 (en) | 2015-11-25 | 2017-06-15 | Gilead Apollo, Llc | Pesticidal compositions and uses thereof |
| CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| WO2018171699A1 (zh) * | 2017-03-24 | 2018-09-27 | 浙江海正药业股份有限公司 | 氰基取代的杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| US11225473B2 (en) | 2019-01-15 | 2022-01-18 | Gilead Sciences, Inc. | FXR (NR1H4) modulating compounds |
| AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
| EP4058144A1 (en) | 2019-11-15 | 2022-09-21 | Gilead Sciences, Inc. | Triazole carbamate pyridyl sulfonamides as lpa receptor antagonists and uses thereof |
| ES2960703T3 (es) | 2019-12-05 | 2024-03-06 | Zhangzhou Pien Tze Huang Pharm | Forma cristalina del compuesto de tieno[2,3-c]piridazina-4(1H)-ona, método de preparación de la misma y uso de la misma |
| ES2965380T3 (es) * | 2019-12-05 | 2024-04-15 | Zhangzhou Pien Tze Huang Pharm | Forma cristalina como inhibidor de ACC1 y ACC2, y método de preparación de la misma y uso de la misma |
| US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
| TWI838626B (zh) | 2020-06-03 | 2024-04-11 | 美商基利科學股份有限公司 | Lpa受體拮抗劑及其用途 |
| US11702407B2 (en) | 2020-06-03 | 2023-07-18 | Gilead Sciences, Inc. | LPA receptor antagonists and uses thereof |
| CN117295717A (zh) | 2021-05-11 | 2023-12-26 | 吉利德科学公司 | Lpa受体拮抗剂及其用途 |
| JP7691522B2 (ja) | 2021-05-13 | 2025-06-11 | ギリアード サイエンシーズ， インコーポレイテッド | Ｌｐａ受容体アンタゴニスト及びそれらの使用 |
| US11939318B2 (en) | 2021-12-08 | 2024-03-26 | Gilead Sciences, Inc. | LPA receptor antagonists and uses thereof |
| CN116267361B (zh) * | 2023-05-10 | 2025-02-25 | 沈阳农业大学 | 一种防治十字花科作物根肿病的方法 |
| CN118127051B (zh) * | 2024-02-06 | 2024-10-29 | 河北农业大学 | 一种StGh93p1基因及其编码蛋白在防治玉米大斑病中的应用 |
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-
2014
- 2014-05-08 BR BR112015028152A patent/BR112015028152A2/pt not_active Application Discontinuation
- 2014-05-08 EP EP14794757.6A patent/EP2994139B1/en not_active Not-in-force
- 2014-05-08 CN CN201480036127.7A patent/CN105358154A/zh active Pending
- 2014-05-08 US US14/890,320 patent/US10208063B2/en active Active
- 2014-05-08 AU AU2014262638A patent/AU2014262638A1/en not_active Abandoned
- 2014-05-08 CA CA2911932A patent/CA2911932A1/en not_active Abandoned
- 2014-05-08 HK HK16109919.1A patent/HK1221661A1/zh unknown
- 2014-05-08 EA EA201591960A patent/EA030942B1/ru not_active IP Right Cessation
- 2014-05-08 WO PCT/US2014/037363 patent/WO2014182945A1/en not_active Ceased
- 2014-05-08 HK HK16109587.2A patent/HK1221411A1/zh unknown
- 2014-05-08 MX MX2015015422A patent/MX2015015422A/es unknown
- 2014-05-08 JP JP2016513083A patent/JP6434498B2/ja active Active
- 2014-05-08 KR KR1020157035039A patent/KR20160006762A/ko not_active Withdrawn
- 2014-05-09 AR ARP140101889A patent/AR096242A1/es unknown
-
2015
- 2015-11-10 CL CL2015003315A patent/CL2015003315A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014262638A1 (en) | 2015-11-26 |
| MX2015015422A (es) | 2016-06-21 |
| CA2911932A1 (en) | 2014-11-13 |
| EA030942B1 (ru) | 2018-10-31 |
| US10208063B2 (en) | 2019-02-19 |
| JP2016520063A (ja) | 2016-07-11 |
| EA201591960A1 (ru) | 2016-06-30 |
| AR096242A1 (es) | 2015-12-16 |
| HK1221411A1 (zh) | 2017-06-02 |
| US20160108061A1 (en) | 2016-04-21 |
| EP2994139A1 (en) | 2016-03-16 |
| WO2014182945A1 (en) | 2014-11-13 |
| KR20160006762A (ko) | 2016-01-19 |
| BR112015028152A2 (pt) | 2017-07-25 |
| EP2994139B1 (en) | 2019-04-10 |
| EP2994139A4 (en) | 2016-11-30 |
| HK1221661A1 (zh) | 2017-06-09 |
| CN105358154A (zh) | 2016-02-24 |
| JP6434498B2 (ja) | 2018-12-05 |
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