HK1221661A1 - Acc抑制剂和其用途 - Google Patents

Acc抑制剂和其用途 Download PDF

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Publication number
HK1221661A1
HK1221661A1 HK16109919.1A HK16109919A HK1221661A1 HK 1221661 A1 HK1221661 A1 HK 1221661A1 HK 16109919 A HK16109919 A HK 16109919A HK 1221661 A1 HK1221661 A1 HK 1221661A1
Authority
HK
Hong Kong
Prior art keywords
acc
subject
inhibitors
acc inhibitors
pyrimidindione
Prior art date
Application number
HK16109919.1A
Other languages
English (en)
Chinese (zh)
Inventor
Jeremy Robert Greenwood
Geraldine C. Harriman
George Borg
Craig E. Masse
Original Assignee
Gilead Apollo, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51867753&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1221661(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Apollo, Llc filed Critical Gilead Apollo, Llc
Publication of HK1221661A1 publication Critical patent/HK1221661A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
HK16109919.1A 2013-05-10 2014-05-08 Acc抑制剂和其用途 HK1221661A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361821828P 2013-05-10 2013-05-10
US61/821,828 2013-05-10
PCT/US2014/037363 WO2014182945A1 (en) 2013-05-10 2014-05-08 Acc inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
HK1221661A1 true HK1221661A1 (zh) 2017-06-09

Family

ID=51867753

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16109919.1A HK1221661A1 (zh) 2013-05-10 2014-05-08 Acc抑制剂和其用途
HK16109587.2A HK1221411A1 (zh) 2013-05-10 2014-05-08 Acc抑制剂和其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16109587.2A HK1221411A1 (zh) 2013-05-10 2014-05-08 Acc抑制剂和其用途

Country Status (14)

Country Link
US (1) US10208063B2 (enExample)
EP (1) EP2994139B1 (enExample)
JP (1) JP6434498B2 (enExample)
KR (1) KR20160006762A (enExample)
CN (1) CN105358154A (enExample)
AR (1) AR096242A1 (enExample)
AU (1) AU2014262638A1 (enExample)
BR (1) BR112015028152A2 (enExample)
CA (1) CA2911932A1 (enExample)
CL (1) CL2015003315A1 (enExample)
EA (1) EA030942B1 (enExample)
HK (2) HK1221661A1 (enExample)
MX (1) MX2015015422A (enExample)
WO (1) WO2014182945A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160005364A (ko) 2013-05-10 2016-01-14 님버스 아폴로, 인코포레이티드 Acc 억제제 및 이의 용도
HK1221420A1 (zh) 2013-05-10 2017-06-02 Gilead Apollo, Inc. Acc抑制剂和其用途
MX2015015417A (es) 2013-05-10 2016-06-21 Nimbus Apollo Inc Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos.
EP3059225A4 (en) 2013-10-17 2017-09-06 Shionogi & Co., Ltd. Novel alkylene derivative
CA2968935C (en) 2014-11-26 2023-03-07 Takeda Pharmaceutical Company Limited Bicyclic compound having an acetyl-coa carboxylase (acc) inhibitory activity
JP2018501276A (ja) * 2015-01-09 2018-01-18 ギリアド アポロ， エルエルシー 非アルコール性脂肪肝疾患の処置のためのａｃｃ阻害剤併用療法
AR106472A1 (es) 2015-10-26 2018-01-17 Gilead Apollo Llc Inhibidores de acc y usos de los mismos
SI3379933T1 (sl) 2015-11-25 2023-07-31 Gilead Apollo, Llc Fungicidni sestavki, ki vsebujejo derivate 2,4-diokso-1,4-dihidrotieno (2,3-d)pirimidina
MX2018006288A (es) 2015-11-25 2018-09-07 Gilead Apollo Llc Inhibidores de acc tipo ester y usos de los mismos.
US20170166582A1 (en) 2015-11-25 2017-06-15 Gilead Apollo, Llc Pyrazole acc inhibitors and uses thereof
AU2016361428A1 (en) 2015-11-25 2018-05-24 Gilead Apollo, Llc Triazole ACC inhibitors and uses thereof
WO2018171698A1 (zh) * 2017-03-24 2018-09-27 浙江海正药业股份有限公司 杂芳基并嘧啶酮类衍生物及其制备方法和用途
CN110431144B (zh) * 2017-03-24 2022-08-05 浙江海正药业股份有限公司 氰基取代的杂芳基并嘧啶酮类衍生物及其制备方法和用途
WO2020150136A1 (en) 2019-01-15 2020-07-23 Gilead Sciences, Inc. Fxr (nr1h4) modulating compounds
AR119594A1 (es) 2019-08-09 2021-12-29 Gilead Sciences Inc Derivados de tienopirimidina como inhibidores acc y usos de los mismos
EP4058144A1 (en) 2019-11-15 2022-09-21 Gilead Sciences, Inc. Triazole carbamate pyridyl sulfonamides as lpa receptor antagonists and uses thereof
WO2021110135A1 (zh) * 2019-12-05 2021-06-10 漳州片仔癀药业股份有限公司 作为acc1和acc2抑制剂的晶型及其制备方法和应用
WO2021110138A1 (zh) * 2019-12-05 2021-06-10 漳州片仔癀药业股份有限公司 噻吩并[2,3-c]哒嗪-4(1H)-酮类化合物的晶型及其制备方法和应用
US11478533B2 (en) 2020-04-27 2022-10-25 Novo Nordisk A/S Semaglutide for use in medicine
TWI838626B (zh) 2020-06-03 2024-04-11 美商基利科學股份有限公司 Lpa受體拮抗劑及其用途
AU2021282986B2 (en) 2020-06-03 2024-03-07 Gilead Sciences, Inc. LPA receptor antagonists and uses thereof
AU2022273631B2 (en) 2021-05-11 2025-04-17 Gilead Sciences, Inc. Lpa receptor antagonists and uses thereof
KR20240007233A (ko) 2021-05-13 2024-01-16 길리애드 사이언시즈, 인코포레이티드 Lpa 수용체 길항제 및 이의 용도
JP7709612B2 (ja) 2021-12-08 2025-07-16 ギリアード サイエンシーズ， インコーポレイテッド Ｌｐａ受容体アンタゴニスト及びそれらの使用
CN116267361B (zh) * 2023-05-10 2025-02-25 沈阳农业大学 一种防治十字花科作物根肿病的方法
CN118127051B (zh) * 2024-02-06 2024-10-29 河北农业大学 一种StGh93p1基因及其编码蛋白在防治玉米大斑病中的应用

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US3325503A (en) 1965-02-18 1967-06-13 Diamond Alkali Co Polychloro derivatives of mono- and dicyano pyridines and a method for their preparation
US3296272A (en) 1965-04-01 1967-01-03 Dow Chemical Co Sulfinyl- and sulfonylpyridines
FR1453897A (fr) 1965-06-16 1966-07-22 Dérivés du thiophène et de thiéno pyridazines
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
US5304732A (en) 1984-03-06 1994-04-19 Mgi Pharma, Inc. Herbicide resistance in plants
GB8524663D0 (en) 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives
FR2629098B1 (fr) 1988-03-23 1990-08-10 Rhone Poulenc Agrochimie Gene chimerique de resistance herbicide
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
DE69034081T2 (de) 1989-03-24 2004-02-12 Syngenta Participations Ag Krankheitsresistente transgene Pflanze
ZW13690A1 (en) 1989-08-30 1990-11-21 Aeci Ltd Active ingredient dosage device
JPH0747582B2 (ja) 1989-12-11 1995-05-24 杏林製薬株式会社 キナゾリン―３―アルカン酸誘導体とその塩およびその製造法
EP0519937B1 (en) 1990-03-12 1994-12-28 E.I. Du Pont De Nemours And Company Water-dispersible or water-soluble pesticide granules from heat-activated binders
EP0536330B1 (en) 1990-06-25 2002-02-27 Monsanto Technology LLC Glyphosate tolerant plants
EP0480679B1 (en) 1990-10-11 1996-09-18 Sumitomo Chemical Company Limited Pesticidal composition
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US6069298A (en) 1993-02-05 2000-05-30 Regents Of The University Of Minnesota Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants
US6303181B1 (en) 1993-05-17 2001-10-16 Electrochemicals Inc. Direct metallization process employing a cationic conditioner and a binder
US5530195A (en) 1994-06-10 1996-06-25 Ciba-Geigy Corporation Bacillus thuringiensis gene encoding a toxin active against insects
US5773704A (en) 1996-04-29 1998-06-30 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Herbicide resistant rice
ES2274546T3 (es) 1996-07-17 2007-05-16 Michigan State University Plantas de remolacha azucarera resistentes al herbicida de imidazolinona.
US5773702A (en) 1996-07-17 1998-06-30 Board Of Trustees Operating Michigan State University Imidazolinone herbicide resistant sugar beet plants
DE19650197A1 (de) 1996-12-04 1998-06-10 Bayer Ag 3-Thiocarbamoylpyrazol-Derivate
TW460476B (en) 1997-04-14 2001-10-21 American Cyanamid Co Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US6420605B1 (en) 1997-09-18 2002-07-16 Basf Aktiengesellschaft Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides
DE19750012A1 (de) 1997-11-12 1999-05-20 Bayer Ag Isothiazolcarbonsäureamide
BR9813376A (pt) 1997-12-04 2001-06-19 Dow Agrosciences Llc Composição fungicidas e métodos e compostos para a preparação das mesmas
GB9817623D0 (en) 1998-08-13 1998-10-07 Glaxo Group Ltd Pharmaceutical compounds
US6348643B1 (en) 1998-10-29 2002-02-19 American Cyanamid Company DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use
IL143157A0 (en) 1998-11-17 2002-04-21 Kumiai Chemical Industry Co Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural bactericides
JP3417862B2 (ja) 1999-02-02 2003-06-16 新東工業株式会社 酸化チタン光触媒高担持シリカゲルおよびその製造方法
US6586617B1 (en) 1999-04-28 2003-07-01 Sumitomo Chemical Takeda Agro Company, Limited Sulfonamide derivatives
DE10021412A1 (de) 1999-12-13 2001-06-21 Bayer Ag Fungizide Wirkstoffkombinationen
ATE290785T1 (de) 2000-01-25 2005-04-15 Syngenta Participations Ag Herbizide zusammensetzung
US6376548B1 (en) 2000-01-28 2002-04-23 Rohm And Haas Company Enhanced propertied pesticides
AU2001259206B2 (en) 2000-04-28 2006-05-25 Basf Aktiengesellschaft Use of the maize x112 mutant ahas 2 gene and imidazolinone herbicides for selection of transgenic monocots, maize, rice and wheat plants resistant to the imidazolinone herbicides
JP2004506432A (ja) 2000-08-25 2004-03-04 シンジェンタ・パティシペーションズ・アクチェンゲゼルシャフト Ｂａｃｉｌｌｕｓｔｈｕｒｉｎｇｉｅｎｓｉｓ殺虫性結晶タンパク質由来の新規殺虫性毒素
EP1322614A2 (en) 2000-09-18 2003-07-02 E. I. du Pont de Nemours and Company Pyridinyl amides and imides for use as fungicides
AU2002228640B2 (en) 2000-11-17 2005-11-10 Dow Agrosciences Llc Compounds having fungicidal activity and processes to make and use same
US6548738B2 (en) 2000-12-26 2003-04-15 Research Development Foundation ACC2-knockout mice and uses thereof
JP5034142B2 (ja) 2001-04-20 2012-09-26 住友化学株式会社 植物病害防除剤組成物
DE10136065A1 (de) 2001-07-25 2003-02-13 Bayer Cropscience Ag Pyrazolylcarboxanilide
FR2828196A1 (fr) 2001-08-03 2003-02-07 Aventis Cropscience Sa Derives de chromone a action fongicide, procede de preparation et application dans le domaine de l'agriculture
AR034760A1 (es) 2001-08-09 2004-03-17 Northwest Plant Breeding Company Plantas de trigo que tienen resistencia aumentada a herbicidas de imidazolinona
ES2377623T3 (es) 2001-08-09 2012-03-29 University Of Saskatchewan Plantas de trigo con resistencia incrementada a herbicidas de imidazolinona.
CA2456314C (en) 2001-08-09 2012-11-13 University Of Saskatchewan Wheat plants having increased resistance to imidazolinone herbicides
ES2330089T3 (es) 2001-08-17 2009-12-04 Mitsui Chemicals Agro, Inc. Derivado de 3-fenoxi-4-piridazinol y composicion herbicida que lo contiene.
US7230167B2 (en) 2001-08-31 2007-06-12 Syngenta Participations Ag Modified Cry3A toxins and nucleic acid sequences coding therefor
US7304070B2 (en) 2001-11-09 2007-12-04 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
US6977300B2 (en) 2001-11-09 2005-12-20 Cv Therapeutics, Inc. A2B adenosine receptor antagonists
AU2002361696A1 (en) 2001-12-17 2003-06-30 Syngenta Participations Ag Novel corn event
WO2003053145A1 (en) 2001-12-21 2003-07-03 Nissan Chemical Industries, Ltd. Bactericidal composition
TWI327462B (en) 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
DE10204390A1 (de) 2002-02-04 2003-08-14 Bayer Cropscience Ag Disubstituierte Thiazolylcarboxanilide
HK1079785B (zh) 2002-03-05 2007-08-10 辛根塔参与股份公司 邻环丙基-n-甲酰苯胺及其作为杀菌剂的用途
PL374007A1 (en) 2002-06-06 2005-09-19 Eisai Co, Ltd. Novel fused imidazole derivative
EP2329708B1 (en) 2002-07-10 2016-10-19 The Department of Agriculture, Western Australia Wheat plants having increased resistance to imidazolinone herbicides
GB0227966D0 (en) 2002-11-29 2003-01-08 Syngenta Participations Ag Organic Compounds
ES2324472T3 (es) 2003-01-06 2009-08-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Herbicidas que inhiben la accion de acetil-coa carboxilasa en vegetales para su uso como pesticidas.
WO2004083193A1 (ja) 2003-03-17 2004-09-30 Sumitomo Chemical Company, Limited アミド化合物およびこれを含有する殺菌剤組成物
WO2004098520A2 (en) 2003-05-01 2004-11-18 Irm Llc Compounds and compositions as protein kinase inhibitors
ES2389767T3 (es) 2003-05-28 2012-10-31 Basf Se Plantas de trigo que tienen mayor tolerancia a herbicidas de imidazolinona
US7230161B2 (en) * 2003-06-23 2007-06-12 Pioneer Hi-Bred International, Inc. Engineering single-gene-controlled staygreen potential into plants utilizing ACC synthase from maize
MXPA06002155A (es) 2003-08-29 2007-01-25 Inst Nac De Technologia Agrope Plantas de arroz que tienen una tolerancia incrementada a los herbicidas de imidazolinona.
TWI355894B (en) 2003-12-19 2012-01-11 Du Pont Herbicidal pyrimidines
ES2347664T3 (es) 2004-03-10 2010-11-03 Basf Se 5,6-dialquil-7-aminotriazolopirimidinas, el procedimiento para su obtencion y su utilizacion para combatir hongos perjudiciales, asi como los productos que las contienen.
AP2006003778A0 (en) 2004-03-10 2006-10-31 Basf Ag 5,6-Dialkyl-7-amino-triazolopyrimidines, method for their production, their use for controlling pat hogenic fungi and agents containing said compounds
MXPA06014019A (es) 2004-06-03 2007-02-08 Du Pont Mezclas fungicidas de compuestos de amidinilfenilo.
WO2005123689A1 (de) 2004-06-18 2005-12-29 Basf Aktiengesellschaft 1-methyl-3-trifluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
EP1761498A1 (de) 2004-06-18 2007-03-14 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
US7947691B2 (en) 2004-07-21 2011-05-24 Athersys, Inc. Cyclic n-hydroxy imides as inhibitors of flap endonuclease and uses thereof
GB0418048D0 (en) 2004-08-12 2004-09-15 Syngenta Participations Ag Method for protecting useful plants or plant propagation material
JP2006131559A (ja) 2004-11-05 2006-05-25 Takeda Chem Ind Ltd 含窒素複素環化合物
AU2006215624A1 (en) 2005-02-16 2006-08-24 Basf Aktiengesellschaft 5-alkoxyalkyl-6-alkyl-7-amino-azolopyrimidines, method for their production, their use for controlling pathogenic fungi and agents containing said substances
DE102005007160A1 (de) 2005-02-16 2006-08-24 Basf Ag Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen
DE102005009458A1 (de) 2005-03-02 2006-09-07 Bayer Cropscience Ag Pyrazolylcarboxanilide
WO2007017262A1 (en) 2005-08-10 2007-02-15 Smithkline Beecham Corporation Xanthine derivatives as selective hm74a agonists
KR101350071B1 (ko) 2006-01-13 2014-01-14 다우 아그로사이언시즈 엘엘씨 6-(다-치환 아릴)-4-아미노피콜리네이트 및 그의제초제로서의 용도
WO2007090624A2 (en) 2006-02-09 2007-08-16 Syngenta Participations Ag A method of protecting a plant propagation material, a plant, and/or plant organs
CA2641766A1 (en) 2006-02-15 2007-08-23 Abbott Laboratories Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome
US20070208040A1 (en) 2006-03-02 2007-09-06 Elfatih Elzein A2a adenosine receptor antagonists
CA2658821C (en) 2006-07-25 2014-10-21 Cephalon, Inc. Pyridizinone derivatives and uses thereof to treat diseases, disorders and/or conditions that may be mediated or modulated by inhibition of h3 receptors
TW200823225A (en) * 2006-11-01 2008-06-01 Astrazeneca Ab New compounds
PE20081559A1 (es) 2007-01-12 2008-11-20 Merck & Co Inc DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA
WO2008103354A2 (en) 2007-02-20 2008-08-28 Cropsolution, Inc. Modulators of acetyl-coenzyme a carboxylase and methods of use thereof
CN101687883B (zh) 2007-05-25 2012-05-23 沃泰克斯药物股份有限公司 囊性纤维化跨膜传导调节因子的调节剂
CN101481380B (zh) 2008-01-08 2012-10-17 浙江医药股份有限公司新昌制药厂 噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途
US8431581B2 (en) 2008-07-02 2013-04-30 Avexa Limited Imidazopyrimidines and uses thereof
US20110244059A1 (en) * 2008-08-20 2011-10-06 The University Of Medicine And Dentistry Of New Jersey Inhibiting obesity progression by inhibiting adipocyte differentiation with a pre-adipocyte autophagy inhibitor
JP5535931B2 (ja) * 2008-10-27 2014-07-02 武田薬品工業株式会社 二環性化合物
US20100113473A1 (en) * 2008-10-30 2010-05-06 Player Mark R Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor
WO2010127212A1 (en) 2009-04-30 2010-11-04 Forest Laboratories Holdings Limited Inhibitors of acetyl-coa carboxylase
US8697739B2 (en) * 2010-07-29 2014-04-15 Novartis Ag Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
AR084032A1 (es) 2010-11-30 2013-04-17 Takeda Pharmaceutical Compuesto biciclico
ME02312B (me) 2011-04-22 2016-06-20 Pfizer DERIVATI PIRAZOLOSPIROKETONA, NAMIJENJENI UPOTREBI KAO INHIBITORI ACETIL-CoA-KARBOKSILAZE
JPWO2013035827A1 (ja) 2011-09-09 2015-03-23 塩野義製薬株式会社 新規オレフィン誘導体
US20130116241A1 (en) 2011-11-09 2013-05-09 Abbvie Inc. Novel inhibitor compounds of phosphodiesterase type 10a
BR112014011351B1 (pt) 2011-11-11 2021-02-17 Gilead Apollo, Llc. inibidores de acc e usos dos mesmos
KR20160005364A (ko) 2013-05-10 2016-01-14 님버스 아폴로, 인코포레이티드 Acc 억제제 및 이의 용도
HK1221420A1 (zh) 2013-05-10 2017-06-02 Gilead Apollo, Inc. Acc抑制剂和其用途
MX2015015417A (es) 2013-05-10 2016-06-21 Nimbus Apollo Inc Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos.

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EA030942B1 (ru) 2018-10-31
MX2015015422A (es) 2016-06-21
JP6434498B2 (ja) 2018-12-05
AU2014262638A1 (en) 2015-11-26
US10208063B2 (en) 2019-02-19
EP2994139B1 (en) 2019-04-10
US20160108061A1 (en) 2016-04-21
HK1221411A1 (zh) 2017-06-02
JP2016520063A (ja) 2016-07-11
KR20160006762A (ko) 2016-01-19
CL2015003315A1 (es) 2016-07-15
WO2014182945A1 (en) 2014-11-13
AR096242A1 (es) 2015-12-16
EP2994139A4 (en) 2016-11-30
BR112015028152A2 (pt) 2017-07-25
EP2994139A1 (en) 2016-03-16
CA2911932A1 (en) 2014-11-13
EA201591960A1 (ru) 2016-06-30

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