CL2015002311A1 - Derivado de piridina monocíclico - Google Patents
Derivado de piridina monocíclicoInfo
- Publication number
- CL2015002311A1 CL2015002311A1 CL2015002311A CL2015002311A CL2015002311A1 CL 2015002311 A1 CL2015002311 A1 CL 2015002311A1 CL 2015002311 A CL2015002311 A CL 2015002311A CL 2015002311 A CL2015002311 A CL 2015002311A CL 2015002311 A1 CL2015002311 A1 CL 2015002311A1
- Authority
- CL
- Chile
- Prior art keywords
- pyridine derivative
- monocyclic pyridine
- monocyclic
- derivative
- ilcarbonil
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361766922P | 2013-02-20 | 2013-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2015002311A1 true CL2015002311A1 (es) | 2016-02-05 |
Family
ID=51351646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2015002311A CL2015002311A1 (es) | 2013-02-20 | 2015-08-18 | Derivado de piridina monocíclico |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8933099B2 (hr) |
| EP (1) | EP2960238B1 (hr) |
| JP (2) | JP5600229B1 (hr) |
| KR (1) | KR102050128B1 (hr) |
| CN (1) | CN105073730B (hr) |
| AR (1) | AR094812A1 (hr) |
| AU (1) | AU2014219811B2 (hr) |
| BR (1) | BR112015019790B1 (hr) |
| CA (1) | CA2901585C (hr) |
| CL (1) | CL2015002311A1 (hr) |
| CY (1) | CY1119220T1 (hr) |
| DK (1) | DK2960238T3 (hr) |
| ES (1) | ES2628495T3 (hr) |
| HK (1) | HK1215949A1 (hr) |
| HR (1) | HRP20170873T1 (hr) |
| HU (1) | HUE032931T2 (hr) |
| IL (1) | IL240623B (hr) |
| JO (1) | JO3261B1 (hr) |
| LT (1) | LT2960238T (hr) |
| ME (1) | ME02755B (hr) |
| MX (1) | MX361870B (hr) |
| MY (1) | MY178760A (hr) |
| NZ (1) | NZ711101A (hr) |
| PE (1) | PE20151509A1 (hr) |
| PH (1) | PH12015501813A1 (hr) |
| PL (1) | PL2960238T3 (hr) |
| PT (1) | PT2960238T (hr) |
| RS (1) | RS56064B1 (hr) |
| RU (1) | RU2645352C2 (hr) |
| SG (1) | SG11201506488WA (hr) |
| SI (1) | SI2960238T1 (hr) |
| TW (4) | TWI672296B (hr) |
| UA (1) | UA116794C2 (hr) |
| WO (1) | WO2014129477A1 (hr) |
| ZA (1) | ZA201505941B (hr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201700703XA (en) | 2014-08-18 | 2017-03-30 | Eisai R&D Man Co Ltd | Salt of monocyclic pyridine derivative and crystal thereof |
| BR112017016392B1 (pt) * | 2015-03-25 | 2023-02-23 | National Cancer Center | Agente terapêutico para câncer do ducto biliar |
| CN115177619A (zh) * | 2015-12-17 | 2022-10-14 | 卫材R&D管理有限公司 | 用于乳腺癌的治疗剂 |
| CN107098884A (zh) * | 2016-02-19 | 2017-08-29 | 中国科学院上海药物研究所 | 一类取代的氨基吡啶类化合物及其制备和用途 |
| WO2019073998A1 (en) * | 2017-10-12 | 2019-04-18 | Eisai R&D Management Co., Ltd. | PHARMACEUTICAL COMPOSITION COMPRISING A TYPICAL KINASE FGFR SELECTIVE INHIBITOR |
| SG11202007591RA (en) | 2018-03-28 | 2020-09-29 | Eisai R&D Man Co Ltd | Therapeutic agent for hepatocellular carcinoma |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| JP2023500906A (ja) | 2019-11-08 | 2023-01-11 | インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） | キナーゼ阻害剤に対する獲得抵抗性を有するがんの処置方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| CA3180128A1 (en) | 2020-04-17 | 2021-10-21 | Eisai R&D Management Co., Ltd. | Breast cancer therapeutic agent |
| KR20230047056A (ko) | 2020-07-31 | 2023-04-06 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 유방암 치료제 |
| US20230330081A1 (en) | 2020-10-28 | 2023-10-19 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumors |
| IL310339A (en) | 2021-08-31 | 2024-03-01 | Eisai R&D Man Co Ltd | A method for the production of a monocyclic pyridine derivative |
| IL310338A (en) | 2021-08-31 | 2024-03-01 | Eisai R&D Man Co Ltd | Production method for a synthetic intermediate of a monocyclic pyridine derivative |
| CN116768856A (zh) * | 2022-03-18 | 2023-09-19 | 上海润石医药科技有限公司 | 一种取代的氨基六元氮杂环类化合物的盐及其晶型、制备方法和应用 |
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| EP1415987B1 (en) | 2000-10-20 | 2007-02-28 | Eisai R&D Management Co., Ltd. | Nitrogenous aromatic ring compounds as anti cancer agents |
| EP1375465A4 (en) | 2001-04-03 | 2006-01-11 | Eisai Co Ltd | CYCLOOCTANON DERIVATIVE AND CYCLODECANON DERIVATIVE AND THEIR USE |
| US20030187026A1 (en) * | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| WO2004020434A1 (ja) * | 2002-08-30 | 2004-03-11 | Eisai Co., Ltd. | 含窒素芳香環誘導体 |
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| EP1615928A1 (en) | 2003-04-10 | 2006-01-18 | F.Hoffmann-La Roche Ag | Pyrimido compounds |
| US20050256154A1 (en) | 2004-05-04 | 2005-11-17 | Kin-Chun Luk | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides |
| GB0512324D0 (en) | 2005-06-16 | 2005-07-27 | Novartis Ag | Organic compounds |
| FR2883286B1 (fr) | 2005-03-16 | 2008-10-03 | Sanofi Aventis Sa | NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT |
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| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
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| US20100130796A1 (en) | 2007-06-25 | 2010-05-27 | Combes David J | Heater suitable for use in a preconcentrator device |
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| CL2008003675A1 (es) * | 2007-12-13 | 2009-03-20 | Wyeth Corp | Compuestos derivados de 5-alquil o alquenil 3-cianopiridinas, procedimiento de preparacion, composicion farmaceutica, util para reducir la actividad incrementada de una enzima en un mamifero, en donde dicha enzima es una proteina quinasa, destinado al tratamiento de la inflamacion, asma, colitis, esclerosis multiple, soriasis, artritis reumatoide. |
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| JP5739820B2 (ja) | 2008-12-30 | 2015-06-24 | アークル インコーポレイテッド | 置換５，６−ジヒドロ−６−フェニルベンゾ［ｆ］イソキノリン−２−アミン化合物 |
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| FR2947546B1 (fr) | 2009-07-03 | 2011-07-01 | Sanofi Aventis | Derives de pyrazoles, leur preparation et leur application en therapeutique |
| BR112012008094A2 (pt) | 2009-08-07 | 2020-08-18 | Chugai Seiyaku Kabushiki Kaisha | derivado de aminopirazol, seu uso, composição farmacêutica que o compreende, agentes para inibir a atividade de fgfr e para prevenir ou tratar câncer |
| KR20120101367A (ko) | 2009-10-30 | 2012-09-13 | 노파르티스 아게 | 3-（2,6-디클로로-3,5-디메톡시-페닐）-1-｛6-［4-（4-에틸-피페라진-1-일）-페닐아미노］-피리미딘-4-일｝-1-메틸-우레아의 ｎ-옥시드 |
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| TWI628176B (zh) | 2013-04-04 | 2018-07-01 | 奧利安公司 | 蛋白質激酶抑制劑 |
-
2014
- 2014-02-17 AR ARP140100495A patent/AR094812A1/es active IP Right Grant
- 2014-02-18 TW TW107134522A patent/TWI672296B/zh active
- 2014-02-18 TW TW103105419A patent/TWI641602B/zh active
- 2014-02-18 ES ES14754294.8T patent/ES2628495T3/es active Active
- 2014-02-18 SG SG11201506488WA patent/SG11201506488WA/en unknown
- 2014-02-18 RS RS20170596A patent/RS56064B1/sr unknown
- 2014-02-18 JO JOP/2014/0039A patent/JO3261B1/ar active
- 2014-02-18 CA CA2901585A patent/CA2901585C/en active Active
- 2014-02-18 MY MYPI2015702696A patent/MY178760A/en unknown
- 2014-02-18 JP JP2014526292A patent/JP5600229B1/ja active Active
- 2014-02-18 PE PE2015001748A patent/PE20151509A1/es active IP Right Grant
- 2014-02-18 UA UAA201508149A patent/UA116794C2/uk unknown
- 2014-02-18 KR KR1020157022252A patent/KR102050128B1/ko active IP Right Grant
- 2014-02-18 TW TW107134526A patent/TWI672139B/zh active
- 2014-02-18 CN CN201480009370.XA patent/CN105073730B/zh active Active
- 2014-02-18 NZ NZ711101A patent/NZ711101A/en unknown
- 2014-02-18 EP EP14754294.8A patent/EP2960238B1/en active Active
- 2014-02-18 SI SI201430247A patent/SI2960238T1/sl unknown
- 2014-02-18 PL PL14754294T patent/PL2960238T3/pl unknown
- 2014-02-18 DK DK14754294.8T patent/DK2960238T3/en active
- 2014-02-18 RU RU2015134558A patent/RU2645352C2/ru active
- 2014-02-18 BR BR112015019790-6A patent/BR112015019790B1/pt active IP Right Grant
- 2014-02-18 AU AU2014219811A patent/AU2014219811B2/en active Active
- 2014-02-18 HU HUE14754294A patent/HUE032931T2/en unknown
- 2014-02-18 MX MX2015010698A patent/MX361870B/es active IP Right Grant
- 2014-02-18 PT PT147542948T patent/PT2960238T/pt unknown
- 2014-02-18 LT LTEP14754294.8T patent/LT2960238T/lt unknown
- 2014-02-18 WO PCT/JP2014/053819 patent/WO2014129477A1/ja active Application Filing
- 2014-02-18 TW TW107134529A patent/TWI672140B/zh active
- 2014-02-18 ME MEP-2017-130A patent/ME02755B/me unknown
- 2014-02-19 US US14/183,864 patent/US8933099B2/en active Active
- 2014-08-14 JP JP2014165311A patent/JP2014237707A/ja active Pending
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2015
- 2015-08-17 IL IL240623A patent/IL240623B/en active IP Right Grant
- 2015-08-18 ZA ZA2015/05941A patent/ZA201505941B/en unknown
- 2015-08-18 PH PH12015501813A patent/PH12015501813A1/en unknown
- 2015-08-18 CL CL2015002311A patent/CL2015002311A1/es unknown
-
2016
- 2016-04-06 HK HK16103911.2A patent/HK1215949A1/zh unknown
-
2017
- 2017-06-07 HR HRP20170873TT patent/HRP20170873T1/hr unknown
- 2017-06-15 CY CY20171100631T patent/CY1119220T1/el unknown
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