PL2960238T3 - Pochodna monocyklicznej pirydyny - Google Patents

Pochodna monocyklicznej pirydyny

Info

Publication number
PL2960238T3
PL2960238T3 PL14754294T PL14754294T PL2960238T3 PL 2960238 T3 PL2960238 T3 PL 2960238T3 PL 14754294 T PL14754294 T PL 14754294T PL 14754294 T PL14754294 T PL 14754294T PL 2960238 T3 PL2960238 T3 PL 2960238T3
Authority
PL
Poland
Prior art keywords
pyridine derivative
monocyclic pyridine
monocyclic
derivative
pyridine
Prior art date
Application number
PL14754294T
Other languages
English (en)
Inventor
Setsuo Funasaka
Toshimi Okada
Keigo Tanaka
Satoshi Nagao
Isao Ohashi
Yoshinobu Yamane
Yusuke Nakatani
Yuki KAROJI
Original Assignee
Eisai R&D Management Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co., Ltd. filed Critical Eisai R&D Management Co., Ltd.
Publication of PL2960238T3 publication Critical patent/PL2960238T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL14754294T 2013-02-20 2014-02-18 Pochodna monocyklicznej pirydyny PL2960238T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361766922P 2013-02-20 2013-02-20

Publications (1)

Publication Number Publication Date
PL2960238T3 true PL2960238T3 (pl) 2017-09-29

Family

ID=51351646

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14754294T PL2960238T3 (pl) 2013-02-20 2014-02-18 Pochodna monocyklicznej pirydyny

Country Status (35)

Country Link
US (1) US8933099B2 (pl)
EP (1) EP2960238B1 (pl)
JP (2) JP5600229B1 (pl)
KR (1) KR102050128B1 (pl)
CN (1) CN105073730B (pl)
AR (1) AR094812A1 (pl)
AU (1) AU2014219811B2 (pl)
BR (1) BR112015019790B1 (pl)
CA (1) CA2901585C (pl)
CL (1) CL2015002311A1 (pl)
CY (1) CY1119220T1 (pl)
DK (1) DK2960238T3 (pl)
ES (1) ES2628495T3 (pl)
HR (1) HRP20170873T1 (pl)
HU (1) HUE032931T2 (pl)
IL (1) IL240623B (pl)
JO (1) JO3261B1 (pl)
LT (1) LT2960238T (pl)
ME (1) ME02755B (pl)
MX (1) MX361870B (pl)
MY (1) MY178760A (pl)
NZ (1) NZ711101A (pl)
PE (1) PE20151509A1 (pl)
PH (1) PH12015501813A1 (pl)
PL (1) PL2960238T3 (pl)
PT (1) PT2960238T (pl)
RS (1) RS56064B1 (pl)
RU (1) RU2645352C2 (pl)
SG (1) SG11201506488WA (pl)
SI (1) SI2960238T1 (pl)
SM (1) SMT201700288T1 (pl)
TW (4) TWI672140B (pl)
UA (1) UA116794C2 (pl)
WO (1) WO2014129477A1 (pl)
ZA (1) ZA201505941B (pl)

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US20200297711A1 (en) * 2017-10-12 2020-09-24 Eisai R&D Management Co., Ltd. Pharmaceutical composition comprising fgfr selective tyrosine kinase inhibitor
JPWO2019189241A1 (ja) 2018-03-28 2021-03-18 エーザイ・アール・アンド・ディー・マネジメント株式会社 肝細胞癌治療剤
EP3942045A1 (en) 2019-03-21 2022-01-26 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
EP4054579A1 (en) 2019-11-08 2022-09-14 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
WO2021210636A1 (ja) 2020-04-17 2021-10-21 エーザイ・アール・アンド・ディー・マネジメント株式会社 乳がん治療剤
CA3185174A1 (en) 2020-07-31 2022-02-03 Eisai R&D Management Co., Ltd. Therapeutic agent for breast cancer
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CN117715902A (zh) * 2021-08-31 2024-03-15 卫材R&D管理有限公司 单环吡啶衍生物的制造方法
JP2023099778A (ja) * 2021-08-31 2023-07-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 単環ピリジン誘導体の製造方法
WO2023032872A1 (ja) 2021-08-31 2023-03-09 エーザイ・アール・アンド・ディー・マネジメント株式会社 単環ピリジン誘導体の合成中間体の製造方法
JP2023099776A (ja) * 2021-08-31 2023-07-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 単環ピリジン誘導体の合成中間体の製造方法
JP7802200B2 (ja) * 2022-03-18 2026-01-19 上▲海▼▲潤▼石医▲薬▼科技有限公司 置換のアミノ6員窒素複素環式化合物の塩及びその結晶形、製造方法と応用
WO2025061013A1 (zh) * 2023-09-18 2025-03-27 上海润石医药科技有限公司 包含杂芳基氧基萘类化合物的药物组合物及其制备方法和应用
TW202606671A (zh) * 2024-06-27 2026-02-16 日商衛材R&D企管股份有限公司 用於預測患有腫瘤的人類受試者的響應可能性之方法

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Also Published As

Publication number Publication date
NZ711101A (en) 2018-08-31
WO2014129477A1 (ja) 2014-08-28
TW201902889A (zh) 2019-01-16
TWI672140B (zh) 2019-09-21
US20140235614A1 (en) 2014-08-21
JP5600229B1 (ja) 2014-10-01
ME02755B (me) 2018-01-20
PE20151509A1 (es) 2015-10-18
PT2960238T (pt) 2017-06-05
LT2960238T (lt) 2017-07-10
TWI672296B (zh) 2019-09-21
MX2015010698A (es) 2016-04-11
TW201900169A (zh) 2019-01-01
JP2014237707A (ja) 2014-12-18
BR112015019790A2 (pt) 2017-07-18
RU2015134558A (ru) 2017-03-24
HRP20170873T1 (hr) 2017-09-08
AU2014219811A1 (en) 2015-09-03
TWI672139B (zh) 2019-09-21
BR112015019790B1 (pt) 2020-12-01
DK2960238T3 (en) 2017-06-26
SMT201700288T1 (it) 2017-07-18
AR094812A1 (es) 2015-08-26
TWI641602B (zh) 2018-11-21
SG11201506488WA (en) 2015-09-29
SI2960238T1 (sl) 2017-07-31
CA2901585A1 (en) 2014-08-28
MY178760A (en) 2020-10-20
IL240623A0 (en) 2015-10-29
ZA201505941B (en) 2016-07-27
EP2960238A4 (en) 2016-08-17
EP2960238B1 (en) 2017-04-05
HUE032931T2 (en) 2017-11-28
RU2645352C2 (ru) 2018-02-21
KR102050128B1 (ko) 2019-11-28
UA116794C2 (uk) 2018-05-10
PH12015501813A1 (en) 2015-12-07
CN105073730B (zh) 2017-10-13
CN105073730A (zh) 2015-11-18
AU2014219811B2 (en) 2017-09-28
JO3261B1 (ar) 2018-09-16
US8933099B2 (en) 2015-01-13
HK1215949A1 (en) 2016-09-30
IL240623B (en) 2019-03-31
KR20150118151A (ko) 2015-10-21
TW201439085A (zh) 2014-10-16
MX361870B (es) 2018-12-18
TW201900168A (zh) 2019-01-01
CL2015002311A1 (es) 2016-02-05
RS56064B1 (sr) 2017-10-31
JPWO2014129477A1 (ja) 2017-02-02
ES2628495T3 (es) 2017-08-03
CY1119220T1 (el) 2018-02-14
EP2960238A1 (en) 2015-12-30
CA2901585C (en) 2019-09-24

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