CL2014003337A1 - Compuestos macrociclicos, inhibidores de virus flaviviridae; composicion farmaceutica que los comprende; metodo para proporcionar inmunomodulacion; y metodo de tratamiento de una infeccion viral por flaviviridae seleccionada de una infeccion por virus de hepatitis b, virus de hepatitis c, dengue, y fiebre amarilla, entre otras. - Google Patents
Compuestos macrociclicos, inhibidores de virus flaviviridae; composicion farmaceutica que los comprende; metodo para proporcionar inmunomodulacion; y metodo de tratamiento de una infeccion viral por flaviviridae seleccionada de una infeccion por virus de hepatitis b, virus de hepatitis c, dengue, y fiebre amarilla, entre otras.Info
- Publication number
- CL2014003337A1 CL2014003337A1 CL2014003337A CL2014003337A CL2014003337A1 CL 2014003337 A1 CL2014003337 A1 CL 2014003337A1 CL 2014003337 A CL2014003337 A CL 2014003337A CL 2014003337 A CL2014003337 A CL 2014003337A CL 2014003337 A1 CL2014003337 A1 CL 2014003337A1
- Authority
- CL
- Chile
- Prior art keywords
- virus
- hepatitis
- flaviviridae
- infection
- dengue
- Prior art date
Links
- 241000710781 Flaviviridae Species 0.000 title 2
- 208000001490 Dengue Diseases 0.000 title 1
- 206010012310 Dengue fever Diseases 0.000 title 1
- 241000711549 Hepacivirus C Species 0.000 title 1
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 208000036142 Viral infection Diseases 0.000 title 1
- 208000003152 Yellow Fever Diseases 0.000 title 1
- 208000025729 dengue disease Diseases 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000002678 macrocyclic compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/504—Pyridazines; Hydrogenated pyridazines forming part of bridged ring systems
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- C—CHEMISTRY; METALLURGY
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D498/18—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/18—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Chemical & Material Sciences (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261657562P | 2012-06-08 | 2012-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014003337A1 true CL2014003337A1 (es) | 2015-07-10 |
Family
ID=48626704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014003337A CL2014003337A1 (es) | 2012-06-08 | 2014-12-05 | Compuestos macrociclicos, inhibidores de virus flaviviridae; composicion farmaceutica que los comprende; metodo para proporcionar inmunomodulacion; y metodo de tratamiento de una infeccion viral por flaviviridae seleccionada de una infeccion por virus de hepatitis b, virus de hepatitis c, dengue, y fiebre amarilla, entre otras. |
Country Status (33)
Families Citing this family (89)
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| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
| SI2861604T1 (sl) | 2012-06-08 | 2017-05-31 | Gilead Sciences, Inc. | Makrociklični inhibitorji flavivirusov |
| US9233974B2 (en) | 2012-12-21 | 2016-01-12 | Gilead Sciences, Inc. | Antiviral compounds |
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| US20150064253A1 (en) | 2013-08-27 | 2015-03-05 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
| WO2015084741A2 (en) | 2013-12-02 | 2015-06-11 | Gilead Pharmasset Llc | Methods of treating hepatitis c virus infection in subjects with cirrhosis |
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| ES2669208T3 (es) | 2014-01-06 | 2018-05-24 | Bristol-Myers Squibb Company | Derivados de pirrolidinilsulfona y su uso como moduladores de ROR gamma |
| SG11201705069YA (en) | 2014-12-26 | 2017-07-28 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
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| EP3355930A4 (en) | 2015-10-01 | 2019-03-06 | Warp Drive Bio, Inc. | METHOD AND REAGENTS FOR THE ANALYSIS OF PROTEIN-PROTEIN INTERFACES |
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