CL2014001154A1 - Compuestos derivados antibioticos de 2-oxo-oxazolidin-3,5-diilo de formula i; composicion farmaceutica; uso para la prevencion o tratamiento de una infeccion bacteriana. - Google Patents
Compuestos derivados antibioticos de 2-oxo-oxazolidin-3,5-diilo de formula i; composicion farmaceutica; uso para la prevencion o tratamiento de una infeccion bacteriana.Info
- Publication number
- CL2014001154A1 CL2014001154A1 CL2014001154A CL2014001154A CL2014001154A1 CL 2014001154 A1 CL2014001154 A1 CL 2014001154A1 CL 2014001154 A CL2014001154 A CL 2014001154A CL 2014001154 A CL2014001154 A CL 2014001154A CL 2014001154 A1 CL2014001154 A1 CL 2014001154A1
- Authority
- CL
- Chile
- Prior art keywords
- oxazolidin
- diyl
- oxo
- prevention
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2011054968 | 2011-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014001154A1 true CL2014001154A1 (es) | 2014-09-12 |
Family
ID=47258051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014001154A CL2014001154A1 (es) | 2011-11-08 | 2014-04-30 | Compuestos derivados antibioticos de 2-oxo-oxazolidin-3,5-diilo de formula i; composicion farmaceutica; uso para la prevencion o tratamiento de una infeccion bacteriana. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9079922B2 (es) |
| EP (1) | EP2776431B1 (es) |
| JP (1) | JP6030146B2 (es) |
| KR (1) | KR20140096337A (es) |
| AR (1) | AR088691A1 (es) |
| AU (1) | AU2012335207B2 (es) |
| BR (1) | BR112014011064A8 (es) |
| CA (1) | CA2854264A1 (es) |
| CL (1) | CL2014001154A1 (es) |
| ES (1) | ES2581056T3 (es) |
| HK (1) | HK1202288A1 (es) |
| IL (1) | IL232463A0 (es) |
| IN (1) | IN2014CN04126A (es) |
| MX (1) | MX344529B (es) |
| PL (1) | PL2776431T3 (es) |
| RU (1) | RU2616609C2 (es) |
| SG (1) | SG11201401710PA (es) |
| TW (1) | TWI594996B (es) |
| WO (1) | WO2013068948A1 (es) |
| ZA (1) | ZA201404176B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2344495T1 (sl) | 2008-10-07 | 2015-03-31 | Actelion Pharmaceuticals Ltd. | Spojine tricikličnega oksazolidinonskega antibiotika |
| BR112015026261A8 (pt) | 2013-04-16 | 2017-12-26 | Actelion Pharmaceuticals Ltd | Derivados biaromáticos antibacterianos |
| AR096135A1 (es) | 2013-05-02 | 2015-12-09 | Actelion Pharmaceuticals Ltd | Derivados de la quinolona |
| AR102256A1 (es) | 2014-10-15 | 2017-02-15 | Actelion Pharmaceuticals Ltd | Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi |
| MA41168A (fr) | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
| MA41169A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Composés antibactériens à large spectre d'activité |
| CA3012569A1 (en) * | 2016-02-08 | 2017-08-17 | Redx Pharma Plc | Antibacterial compounds |
| CA3012583A1 (en) | 2016-02-08 | 2017-08-17 | Redx Pharma Plc | Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds |
| GB201602235D0 (en) * | 2016-02-08 | 2016-03-23 | Redx Pharma Plc | Antibacterial compounds |
| US10640488B2 (en) | 2016-06-08 | 2020-05-05 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Antibacterial compounds |
| TW201833120A (zh) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
| US10912780B2 (en) | 2017-06-08 | 2021-02-09 | Bugworks Research, Inc. | Heterocyclic compounds useful as anti-bacterial agents and method for production thereof |
| CN111527093B (zh) * | 2017-11-29 | 2023-06-09 | 巴格沃克斯研究有限公司 | 抗菌杂环化合物及其合成 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149104A (en) | 1961-01-03 | 1964-09-15 | Sterling Drug Inc | 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters |
| DE2362553A1 (de) | 1972-12-18 | 1974-06-20 | Dainippon Pharmaceutical Co | Neue piperazinderivate |
| SE444566B (sv) | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| GB1598915A (en) | 1977-09-20 | 1981-09-23 | Bellon Labor Sa Roger | 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them |
| CS274601B2 (en) | 1983-07-27 | 1991-09-15 | Dainippon Pharmaceutical Co | Method of 1,8-naphthyridine derivative production |
| JPS62205060A (ja) | 1986-03-04 | 1987-09-09 | Kyorin Pharmaceut Co Ltd | ８位置換キノロンカルボン酸誘導体 |
| DK164287A (da) | 1986-03-31 | 1987-10-01 | Sankyo Co | Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse |
| JP2631854B2 (ja) | 1987-12-23 | 1997-07-16 | 藤本製薬株式会社 | 新規な１，８−ナフチリジン誘導体 |
| DE4301246A1 (de) | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
| EP1553093A1 (en) | 2002-06-28 | 2005-07-13 | Kaneka Corporation | Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for the synthesis thereof and process for preparation of the intermediates |
| BRPI0409955A (pt) * | 2003-04-30 | 2006-04-25 | Morphochem Ag Komb Chemie | uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções |
| NZ547382A (en) * | 2003-12-18 | 2009-11-27 | Morphochem Ag Komb Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| AU2005279050A1 (en) * | 2004-07-30 | 2006-03-09 | Centre National De La Recherche Scientifique (Cnrs) | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, and the synthesis and uses thereof as antibacterial agents |
| CA2578081A1 (en) | 2004-09-01 | 2006-03-09 | Ubitrak Inc. | System for gaming chip identification and counting |
| US20090156577A1 (en) | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| WO2007118130A2 (en) | 2006-04-06 | 2007-10-18 | Glaxo Group Limited | Antibacterial agents |
| MY148847A (en) * | 2006-11-10 | 2013-06-14 | Actelion Pharmaceuticals Ltd | 5-hydroxymethyl-oxazolidin-2-one derivatives |
| CL2008001002A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| CL2008001003A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| RU2492169C2 (ru) * | 2007-12-18 | 2013-09-10 | Актелион Фармасьютиклз Лтд | Производные 5-аминоциклилметилоксазолидин-2-она |
| US8349826B2 (en) * | 2008-02-22 | 2013-01-08 | Actelion Pharmaceuticals Ltd. | Oxazolidinone derivatives |
| SI2344495T1 (sl) | 2008-10-07 | 2015-03-31 | Actelion Pharmaceuticals Ltd. | Spojine tricikličnega oksazolidinonskega antibiotika |
| EP2346862B1 (en) * | 2008-10-10 | 2012-09-12 | Actelion Pharmaceuticals Ltd. | 2-benzothiophenyl-and 2-naphthyl-0xaz0lidin0nes and their azaisostere analogues as antibacterial agents |
| BRPI0920870A2 (pt) | 2008-10-10 | 2018-06-26 | Actelion Pharmaceuticals Ltd | antibióticos de oxazolidinila. |
| TW201121965A (en) | 2009-09-28 | 2011-07-01 | Lg Life Sciences Ltd | Use of a quinolone derivative containing 7-(4-aminomethyl-3-oxime)pyrrolidine group that is capable of inducing granulocyte colony stimulating factor for treatment of neutropenia and recovery of hematopoiesis |
| CN101792443A (zh) | 2010-03-09 | 2010-08-04 | 北京欧凯纳斯科技有限公司 | 氟代喹诺酮衍生物及其制备方法和用途 |
-
2012
- 2012-11-07 KR KR1020147014957A patent/KR20140096337A/ko active IP Right Grant
- 2012-11-07 ES ES12791863.9T patent/ES2581056T3/es active Active
- 2012-11-07 PL PL12791863.9T patent/PL2776431T3/pl unknown
- 2012-11-07 BR BR112014011064A patent/BR112014011064A8/pt not_active Application Discontinuation
- 2012-11-07 AU AU2012335207A patent/AU2012335207B2/en not_active Ceased
- 2012-11-07 MX MX2014005637A patent/MX344529B/es active IP Right Grant
- 2012-11-07 JP JP2014540612A patent/JP6030146B2/ja not_active Expired - Fee Related
- 2012-11-07 WO PCT/IB2012/056236 patent/WO2013068948A1/en active Application Filing
- 2012-11-07 IN IN4126CHN2014 patent/IN2014CN04126A/en unknown
- 2012-11-07 SG SG11201401710PA patent/SG11201401710PA/en unknown
- 2012-11-07 EP EP12791863.9A patent/EP2776431B1/en not_active Not-in-force
- 2012-11-07 CA CA2854264A patent/CA2854264A1/en not_active Abandoned
- 2012-11-07 TW TW101141423A patent/TWI594996B/zh not_active IP Right Cessation
- 2012-11-07 RU RU2014123109A patent/RU2616609C2/ru not_active IP Right Cessation
- 2012-11-07 AR ARP120104192A patent/AR088691A1/es unknown
- 2012-11-07 US US14/356,896 patent/US9079922B2/en not_active Expired - Fee Related
-
2014
- 2014-04-30 CL CL2014001154A patent/CL2014001154A1/es unknown
- 2014-05-05 IL IL232463A patent/IL232463A0/en unknown
- 2014-06-06 ZA ZA2014/04176A patent/ZA201404176B/en unknown
-
2015
- 2015-03-16 HK HK15102622.5A patent/HK1202288A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140096337A (ko) | 2014-08-05 |
| HK1202288A1 (en) | 2015-09-25 |
| BR112014011064A8 (pt) | 2017-12-26 |
| RU2014123109A (ru) | 2015-12-20 |
| ZA201404176B (en) | 2016-05-25 |
| CA2854264A1 (en) | 2013-05-16 |
| PL2776431T3 (pl) | 2016-11-30 |
| AU2012335207B2 (en) | 2017-05-25 |
| BR112014011064A2 (pt) | 2017-06-13 |
| AR088691A1 (es) | 2014-06-25 |
| MX2014005637A (es) | 2014-06-23 |
| SG11201401710PA (en) | 2014-09-26 |
| WO2013068948A1 (en) | 2013-05-16 |
| CN103917539A (zh) | 2014-07-09 |
| MX344529B (es) | 2016-12-19 |
| JP2014532754A (ja) | 2014-12-08 |
| TWI594996B (zh) | 2017-08-11 |
| TW201326166A (zh) | 2013-07-01 |
| RU2616609C2 (ru) | 2017-04-18 |
| US20150051188A1 (en) | 2015-02-19 |
| AU2012335207A1 (en) | 2014-07-03 |
| JP6030146B2 (ja) | 2016-11-24 |
| EP2776431A1 (en) | 2014-09-17 |
| US9079922B2 (en) | 2015-07-14 |
| ES2581056T3 (es) | 2016-08-31 |
| EP2776431B1 (en) | 2016-05-04 |
| IN2014CN04126A (es) | 2015-07-10 |
| IL232463A0 (en) | 2014-06-30 |
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