IN2014CN04126A - - Google Patents
Download PDFInfo
- Publication number
- IN2014CN04126A IN2014CN04126A IN4126CHN2014A IN2014CN04126A IN 2014CN04126 A IN2014CN04126 A IN 2014CN04126A IN 4126CHN2014 A IN4126CHN2014 A IN 4126CHN2014A IN 2014CN04126 A IN2014CN04126 A IN 2014CN04126A
- Authority
- IN
- India
- Prior art keywords
- attachment
- group
- point
- compounds
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Abstract
1a1b1a1b 1a" "1b213133534413The invention relates to antibacterial compounds of formula I (Fornula I) (I) wherein R represents H or carboxy and R represents H or R and R represent together either the group * C(0) NH S or the group * C(OH)=N S wherein "*" represents the point of attachment of R and represents the point of attachment of R; R represents H (C C)alkyl hydroxy (CC)alkyl benzyl or (C C)cycloalkyl; R represents H or halogen; U represents N or CR; wherein R is H or (C C)alkoxy; A represents CH B represents NH and m represents 1 or 2 and n represents 1 or 2; or A represents N B is absent m represents 2 and n represents 2; Y represents CH or N; and Q represents O or S; and salts of such compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2011054968 | 2011-11-08 | ||
| PCT/IB2012/056236 WO2013068948A1 (en) | 2011-11-08 | 2012-11-07 | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04126A true IN2014CN04126A (en) | 2015-07-10 |
Family
ID=47258051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4126CHN2014 IN2014CN04126A (en) | 2011-11-08 | 2012-11-07 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9079922B2 (en) |
| EP (1) | EP2776431B1 (en) |
| JP (1) | JP6030146B2 (en) |
| KR (1) | KR20140096337A (en) |
| AR (1) | AR088691A1 (en) |
| AU (1) | AU2012335207B2 (en) |
| BR (1) | BR112014011064A8 (en) |
| CA (1) | CA2854264A1 (en) |
| CL (1) | CL2014001154A1 (en) |
| ES (1) | ES2581056T3 (en) |
| HK (1) | HK1202288A1 (en) |
| IL (1) | IL232463A0 (en) |
| IN (1) | IN2014CN04126A (en) |
| MX (1) | MX344529B (en) |
| PL (1) | PL2776431T3 (en) |
| RU (1) | RU2616609C2 (en) |
| SG (1) | SG11201401710PA (en) |
| TW (1) | TWI594996B (en) |
| WO (1) | WO2013068948A1 (en) |
| ZA (1) | ZA201404176B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104151316B (en) | 2008-10-07 | 2016-06-15 | 埃科特莱茵药品有限公司 | Tricyclazole alkanone Antibiotique composition |
| ES2640482T3 (en) | 2013-04-16 | 2017-11-03 | Idorsia Pharmaceuticals Ltd | Antibacterial biaromatic derivatives |
| AR096135A1 (en) | 2013-05-02 | 2015-12-09 | Actelion Pharmaceuticals Ltd | DERIVATIVES OF QUINOLONA |
| AR102256A1 (en) | 2014-10-15 | 2017-02-15 | Actelion Pharmaceuticals Ltd | ANTIBACTERIAL BASIC BIAROMATIC DERIVATIVES WITH REPLACEMENT OF AMINOALCOXI |
| MA41168A (en) | 2014-12-17 | 2017-10-24 | Acraf | NEW ANTIBACTERIAL COMPOUNDS |
| MA41169A (en) * | 2014-12-17 | 2017-10-24 | Acraf | WIDE-SPECTRUM ANTIBACTERIAL COMPOUNDS |
| AU2017218556A1 (en) | 2016-02-08 | 2018-08-09 | Redx Pharma Plc | Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds |
| GB201602235D0 (en) * | 2016-02-08 | 2016-03-23 | Redx Pharma Plc | Antibacterial compounds |
| EP3414246A1 (en) * | 2016-02-08 | 2018-12-19 | Redx Pharma PLC | Antibacterial compounds |
| LT3468975T (en) | 2016-06-08 | 2020-08-10 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | New antibacterial compounds |
| TW201833120A (en) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | Aryloxazolidinone antibiotic compounds |
| ES2942761T3 (en) | 2017-06-08 | 2023-06-06 | Bugworks Res Inc | Heterocyclic compounds useful as antibacterial agents and method for the production thereof |
| JP7390728B2 (en) | 2017-11-29 | 2023-12-04 | バグワークス・リサーチ・インコーポレイテッド | Antibacterial heterocyclic compounds and their synthesis |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149104A (en) | 1961-01-03 | 1964-09-15 | Sterling Drug Inc | 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters |
| HU168497B (en) | 1972-12-18 | 1976-05-28 | ||
| SE444566B (en) | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-DIALKYLAMINE-6-HALOGEN-4-OXO-1,4-DIHYDROQINOLINE-3-CARBOXYLIC ACID, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATION OF THEREOF |
| GB1598915A (en) | 1977-09-20 | 1981-09-23 | Bellon Labor Sa Roger | 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them |
| CS274601B2 (en) | 1983-07-27 | 1991-09-15 | Dainippon Pharmaceutical Co | Method of 1,8-naphthyridine derivative production |
| JPS62205060A (en) | 1986-03-04 | 1987-09-09 | Kyorin Pharmaceut Co Ltd | 8-substituted quinolonecarboxylic acid derivative |
| FI871419A (en) | 1986-03-31 | 1987-10-01 | Sankyo Co | QUINOLIN-3-CARBOXYL SYRADERIVES, DERAS FRAMSTAELLNING OCH ANVAENDNING. |
| JP2631854B2 (en) | 1987-12-23 | 1997-07-16 | 藤本製薬株式会社 | Novel 1,8-naphthyridine derivative |
| DE4301246A1 (en) | 1993-01-19 | 1994-07-21 | Bayer Ag | Quinolone and naphthyridonecarboxylic acid derivatives |
| AU2003244235A1 (en) | 2002-06-28 | 2004-01-19 | Kaneka Corporation | Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for the synthesis thereof and process for preparation of the intermediates |
| US20070155714A1 (en) * | 2003-04-30 | 2007-07-05 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections |
| PL1709044T5 (en) * | 2003-12-18 | 2014-03-31 | Morphochem Aktiengesellschaft Fuer Komb Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| CA2572442A1 (en) | 2004-07-30 | 2006-03-09 | Palumed S.A. | Hybrid qa molecules wherein q is an aminoquinoline and a is an antibiotic residue, their synthesis and their uses as antibacterial agent |
| WO2006024171A1 (en) | 2004-09-01 | 2006-03-09 | Ubitrak Inc. | System for gaming chip identification and counting |
| US20090156577A1 (en) | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| US7709496B2 (en) | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Antibacterial agents |
| WO2008056335A1 (en) * | 2006-11-10 | 2008-05-15 | Actelion Pharmaceuticals Ltd | 5-hydroxymethyl-oxazolidin-2-one derivatives |
| CL2008001003A1 (en) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | COMPOUNDS DERIVED FROM OXAZOLIDINONA; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO PREPARE A MEDICINAL PRODUCT TO TREAT A BACTERIAL INFECTION. |
| CL2008001002A1 (en) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | COMPOUNDS DERIVED FROM OXAZOLIDINONA; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO PREPARE A MEDICINAL PRODUCT TO TREAT A BACTERIAL INFECTION. |
| KR101578234B1 (en) * | 2007-12-18 | 2015-12-16 | 액테리온 파마슈티칼 리미티드 | 5-aminocyclylmethyl-oxazolidin-2-one derivatives |
| CA2713187C (en) * | 2008-02-22 | 2016-06-07 | Actelion Pharmaceuticals Ltd | Oxazolidinone derivatives |
| CN104151316B (en) | 2008-10-07 | 2016-06-15 | 埃科特莱茵药品有限公司 | Tricyclazole alkanone Antibiotique composition |
| TWI436999B (en) * | 2008-10-10 | 2014-05-11 | Actelion Pharmaceuticals Ltd | Oxazolidinyl antibiotics |
| US20110195949A1 (en) * | 2008-10-10 | 2011-08-11 | Actelion Pharmaceuticals Ltd. | 2-benzothiophenyl- and 2-naphthyl-oxazolidinones and their azaisostere analogues as antibacterial agents |
| TW201121965A (en) | 2009-09-28 | 2011-07-01 | Lg Life Sciences Ltd | Use of a quinolone derivative containing 7-(4-aminomethyl-3-oxime)pyrrolidine group that is capable of inducing granulocyte colony stimulating factor for treatment of neutropenia and recovery of hematopoiesis |
| CN101792443A (en) | 2010-03-09 | 2010-08-04 | 北京欧凯纳斯科技有限公司 | Fluoro-carbostyril derivative as well as preparation method and application thereof |
-
2012
- 2012-11-07 WO PCT/IB2012/056236 patent/WO2013068948A1/en active Application Filing
- 2012-11-07 SG SG11201401710PA patent/SG11201401710PA/en unknown
- 2012-11-07 KR KR1020147014957A patent/KR20140096337A/en active IP Right Grant
- 2012-11-07 JP JP2014540612A patent/JP6030146B2/en not_active Expired - Fee Related
- 2012-11-07 MX MX2014005637A patent/MX344529B/en active IP Right Grant
- 2012-11-07 BR BR112014011064A patent/BR112014011064A8/en not_active Application Discontinuation
- 2012-11-07 PL PL12791863.9T patent/PL2776431T3/en unknown
- 2012-11-07 CA CA2854264A patent/CA2854264A1/en not_active Abandoned
- 2012-11-07 US US14/356,896 patent/US9079922B2/en not_active Expired - Fee Related
- 2012-11-07 AR ARP120104192A patent/AR088691A1/en unknown
- 2012-11-07 IN IN4126CHN2014 patent/IN2014CN04126A/en unknown
- 2012-11-07 RU RU2014123109A patent/RU2616609C2/en not_active IP Right Cessation
- 2012-11-07 ES ES12791863.9T patent/ES2581056T3/en active Active
- 2012-11-07 TW TW101141423A patent/TWI594996B/en not_active IP Right Cessation
- 2012-11-07 EP EP12791863.9A patent/EP2776431B1/en not_active Not-in-force
- 2012-11-07 AU AU2012335207A patent/AU2012335207B2/en not_active Ceased
-
2014
- 2014-04-30 CL CL2014001154A patent/CL2014001154A1/en unknown
- 2014-05-05 IL IL232463A patent/IL232463A0/en unknown
- 2014-06-06 ZA ZA2014/04176A patent/ZA201404176B/en unknown
-
2015
- 2015-03-16 HK HK15102622.5A patent/HK1202288A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014123109A (en) | 2015-12-20 |
| RU2616609C2 (en) | 2017-04-18 |
| WO2013068948A1 (en) | 2013-05-16 |
| TW201326166A (en) | 2013-07-01 |
| MX344529B (en) | 2016-12-19 |
| TWI594996B (en) | 2017-08-11 |
| US9079922B2 (en) | 2015-07-14 |
| US20150051188A1 (en) | 2015-02-19 |
| AR088691A1 (en) | 2014-06-25 |
| ZA201404176B (en) | 2016-05-25 |
| CN103917539A (en) | 2014-07-09 |
| CA2854264A1 (en) | 2013-05-16 |
| BR112014011064A2 (en) | 2017-06-13 |
| EP2776431B1 (en) | 2016-05-04 |
| CL2014001154A1 (en) | 2014-09-12 |
| JP2014532754A (en) | 2014-12-08 |
| PL2776431T3 (en) | 2016-11-30 |
| JP6030146B2 (en) | 2016-11-24 |
| SG11201401710PA (en) | 2014-09-26 |
| HK1202288A1 (en) | 2015-09-25 |
| BR112014011064A8 (en) | 2017-12-26 |
| IL232463A0 (en) | 2014-06-30 |
| KR20140096337A (en) | 2014-08-05 |
| MX2014005637A (en) | 2014-06-23 |
| EP2776431A1 (en) | 2014-09-17 |
| AU2012335207A1 (en) | 2014-07-03 |
| AU2012335207B2 (en) | 2017-05-25 |
| ES2581056T3 (en) | 2016-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014CN04126A (en) | ||
| PH12017501192A1 (en) | Certain amino-pyridazines, compositions thereof, and methods of their use | |
| AU2012313888A8 (en) | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH | |
| MA40301B1 (en) | Indolecarboxamide compounds useful as kinase inhibitors | |
| EA201201378A1 (en) | DETERMINED AMINOPYRIMIDINES, COMPOSITIONS ON THEIR BASIS AND METHODS OF THEIR USE | |
| JO3317B1 (en) | Tetrahydropyrrolothiazine compounds | |
| MY146638A (en) | Insecticidal aryl isoxazoline derivatives | |
| EA201290800A1 (en) | Heterocyclic Compound | |
| MY172860A (en) | Dimethyl-benzoic acid compounds | |
| EP2575815A4 (en) | Glycine transporter-1 inhibitors, methods of making them, and uses thereof | |
| BR112014031616A2 (en) | phenoxyethyl piperidine compounds | |
| IN2014DN07996A (en) | ||
| JO3143B1 (en) | Tetrahydropyrrolothiazine compounds | |
| MY160392A (en) | Triptolide prodrugs | |
| MY160321A (en) | Pesticidal composition and its use | |
| BR112014026305A2 (en) | quinazolidinedione derivative | |
| BR112015026967A2 (en) | phenoxyethyl dihydro-1h-isoquinoline compounds | |
| MY160882A (en) | Biocidal composition and method | |
| EP2602254A4 (en) | Heterocyclic compound | |
| NZ605804A (en) | New aminopyrazoloquinazolines | |
| IN2012DN03343A (en) | ||
| TR201818771T4 (en) | Compounds for Use in the Treatment of Cognitive Disorders | |
| IN2014CN02036A (en) | ||
| IN2012DN03104A (en) | ||
| GB201020397D0 (en) | Compounds |