CL2013003796A1 - Proceso de separacion cromatografico para recuperar producto de acido graso (pufa) en lecho movil real o simulado para producir pufa altamente purificado a partir de mezcla de alimentación. - Google Patents

Proceso de separacion cromatografico para recuperar producto de acido graso (pufa) en lecho movil real o simulado para producir pufa altamente purificado a partir de mezcla de alimentación.

Info

Publication number
CL2013003796A1
CL2013003796A1 CL2013003796A CL2013003796A CL2013003796A1 CL 2013003796 A1 CL2013003796 A1 CL 2013003796A1 CL 2013003796 A CL2013003796 A CL 2013003796A CL 2013003796 A CL2013003796 A CL 2013003796A CL 2013003796 A1 CL2013003796 A1 CL 2013003796A1
Authority
CL
Chile
Prior art keywords
zone
product
puff
fatty acid
separation process
Prior art date
Application number
CL2013003796A
Other languages
English (en)
Inventor
Adam Kelliher
Angus Morrison
Anil Oroskar
Rema Rakesh Vikraman Nair
Abhilesh Agarwal
Original Assignee
Basf Pharma Callanish Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Pharma Callanish Ltd filed Critical Basf Pharma Callanish Ltd
Publication of CL2013003796A1 publication Critical patent/CL2013003796A1/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/185—Simulated moving beds characterized by the components to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/10—Refining fats or fatty oils by adsorption
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
    • C11B7/0008—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
    • C11B7/0008—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents
    • C11B7/0033—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents in solvents containing other heteroatoms in their molecule
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/005—Splitting up mixtures of fatty acids into their constituents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/007—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids using organic solvents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Sustainable Development (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

LA PRESENTE INVENCIÓN PROVEE UN PROCESO DE SEPARACIÓN CROMATOGRÁFICA, CON EL FIN DE RECUPERAR UN PRODUCTO DEL ÁCIDO GRASO POLIINSATURADO (PUFA), A PARTIR DE UNA MEZCLA DE ALIMENTACIÓN, CUYO PROCESO COMPRENDE LA INTRODUCCIÓN DE LA MEZCLA DE ALIMENTACIÓN A UN APARATO DE CROMATOGRAFIA EN LECHO MÓVIL REAL O SIMULADO, QUE TIENE UNA PLURALIDAD DE COLUMNAS DE CROMATOGRAFÍA ENLAZADAS CONTENIENDO, COMO ELUYENTE, UN SOLVENTE ORGÁNICO ACUOSO, DONDE EL APARATO TIENE UNA PLURALIDAD DE ZONAS COMPRENDIENDO AL MENOS UNA PRIMERA ZONA Y UNA SEGUNDA ZONA, TENIENDO CADA ZONA UNA CORRIENTE DE) EXTRACTO Y UNA CORRIENTE DEL REFINADO, A PARTIR DE LA CUAL PUEDE SER RECOLECTADO LIQUIDO DESDE DICHA PLURALIDAD DE COLUMNAS DE CROMATOGRAFÍA ENLAZADAS, Y DONDE (A) UNA CORRIENTE DEL REFINADO CONTENIENDO EL PRODUCTO DEL PUFA, JUNTO CON LOS COMPONENTES MÁS POLARES, ES RECOLECTADA DESDE UNA COLUMNA EN LA PRIMERA ZONA E INTRODUCIDA A UNA COLUMNA NO ADYACENTE EN LA SEGUNDA ZONA, Y/O (B) UNA CORRIENTE DEL EXTRACTO CONTENIENDO EL PRODUCTO DEL RUFA, JUNTO CON LOS COMPONENTES MENOS POLARES, ES RECOLECTADA DESDE UNA COLUMNA EN LA SEGUNDA ZONA E INTRODUCIDA A UNA COLUMNA NO ADYACENTE EN LA PRIMERA ZONA, SIENDO DICHO PRODUCTO DEL PUFA SEPARADO DESDE DIFERENTES COMPONENTES DE LA MEZCLA DE ALIMENTACIÓN EN CADA ZONA, Y DONDE EL SOLVENTE ORGÁNICO ACUOSO ES DISTINTO AL ALCOHOL ACUOSO.        
CL2013003796A 2011-07-06 2013-12-30 Proceso de separacion cromatografico para recuperar producto de acido graso (pufa) en lecho movil real o simulado para producir pufa altamente purificado a partir de mezcla de alimentación. CL2013003796A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1111601.9A GB201111601D0 (en) 2011-07-06 2011-07-06 New process

Publications (1)

Publication Number Publication Date
CL2013003796A1 true CL2013003796A1 (es) 2014-07-04

Family

ID=44544346

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013003796A CL2013003796A1 (es) 2011-07-06 2013-12-30 Proceso de separacion cromatografico para recuperar producto de acido graso (pufa) en lecho movil real o simulado para producir pufa altamente purificado a partir de mezcla de alimentación.

Country Status (13)

Country Link
US (1) US9370730B2 (es)
EP (1) EP2613858B1 (es)
JP (2) JP6153519B2 (es)
KR (1) KR101594722B1 (es)
CN (1) CN103764242B (es)
AU (1) AU2012280065B2 (es)
BR (1) BR112014000163A2 (es)
CA (1) CA2815296C (es)
CL (1) CL2013003796A1 (es)
ES (1) ES2536911T3 (es)
GB (1) GB201111601D0 (es)
PE (1) PE20142016A1 (es)
WO (1) WO2013005046A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2519332B1 (en) 2009-12-30 2014-03-05 BASF Pharma (Callanish) Limited Simulated moving bed chromatographic separation process for the purification of polyunsaturated fatty acids
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
CN109679768A (zh) * 2013-05-07 2019-04-26 诺瓦塞普集团 用于生产高度纯化的多不饱和脂肪酸的色谱方法
EP2883860B1 (fr) 2013-12-11 2016-08-24 Novasep Process Procédé chromatographique de production d'acides gras polyinsaturés
WO2015104464A1 (fr) 2014-01-07 2015-07-16 Novasep Process Procédé de purification d'acides aminés aromatiques
WO2016036757A1 (en) * 2014-09-02 2016-03-10 INVISTA Technologies S.á.r.l. Purification of long chain diacids
WO2016164748A1 (en) 2015-04-08 2016-10-13 Invista North America S.A.R.L. Materials and methods for the selective recovery of monovalent products from aqueous solutions using continuous ion exchange
US10265642B2 (en) * 2015-04-10 2019-04-23 Invista North America S.A.R.L. Process for separation of diamines and/or omega-aminoacids from a feed fixture
TWI648393B (zh) * 2017-08-15 2019-01-21 喬璞科技有限公司 純化不飽和脂肪酸以及純化亞麻酸的方法
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
WO2020060970A1 (en) 2018-09-18 2020-03-26 Invista North America S.A.R.L. Systems and methods for recovering amines and their derivates from aqueous mixtures
EP3839497B1 (en) * 2018-11-16 2023-03-29 Organo Corporation Chromatographic separation method using simulated moving-bed technique, and chromatographic separation system using simulated moving-bed technique
CN112169373B (zh) * 2019-07-05 2022-03-11 中国石油化工股份有限公司 一种模拟移动床吸附分离目标产物的方法
CN113831244A (zh) * 2020-06-24 2021-12-24 北京创新通恒科技有限公司 一种提纯高纯EPA-ee分离设备及工艺方法
AU2022413641A1 (en) 2021-12-17 2024-07-04 Basf Se Chromatographic separation process for efficient purification of polyunsaturated fatty acids
CN115073292B (zh) * 2022-07-01 2023-10-03 江苏汉邦科技股份有限公司 一种二十碳五烯酸乙酯的制备方法

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US571930A (en) * 1896-11-24 Tension device for wire fences
US2985589A (en) 1957-05-22 1961-05-23 Universal Oil Prod Co Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets
US3761533A (en) 1970-07-23 1973-09-25 Toray Industries Separation process of components of feed mixture utilizing solid sorbent
US3706812A (en) 1970-12-07 1972-12-19 Universal Oil Prod Co Fluid-solid contacting apparatus
US3696107A (en) 1971-05-27 1972-10-03 Richard W Neuzil Improved hydrocarbon separation process
US4048111A (en) 1975-06-12 1977-09-13 Uop Inc. Method for manufacturing an adsorbent useful for olefin separation
US4036745A (en) 1975-09-24 1977-07-19 Uop Inc. Process for separating normal and isoparaffins
US4049688A (en) 1976-08-02 1977-09-20 Uop Inc. Process for separating esters of fatty acids by selective adsorption
US4048205A (en) 1976-08-02 1977-09-13 Uop Inc. Process for separating an ester of a monoethanoid fatty acid
US4313015A (en) 1980-02-07 1982-01-26 Uop Inc. Separation process
US4353838A (en) 1981-02-13 1982-10-12 Uop Inc. Process for separating a monoethanoid fatty acid
US4353839A (en) 1981-02-25 1982-10-12 Uop Inc. Process for separating saturated fatty acids
US4524030A (en) 1981-04-10 1985-06-18 Uop Inc. Process for separating fatty acids
US4511514A (en) 1981-04-10 1985-04-16 Uop Inc. Process for separating oleic acid from linoleic acid
US4522761A (en) 1981-04-10 1985-06-11 Uop Inc. Process for separating fatty acids from rosin acids
US4519952A (en) 1981-04-10 1985-05-28 Uop Inc. Process for separating fatty acids from unsaponifiables
IN158368B (es) 1981-04-10 1986-11-01 Uop Inc
US4404145A (en) 1981-04-10 1983-09-13 Uop Inc. Process for separating fatty acids from rosin acids
US4329280A (en) 1981-04-10 1982-05-11 Uop Inc. Process for separating esters of fatty and rosin acids
US4486618A (en) 1981-07-30 1984-12-04 Uop Inc. Process for separating C6 olefin hydrocarbons
JPS5888339U (ja) 1981-12-10 1983-06-15 株式会社　カネノ製作所 不透明シ−ト入り物品収容具
JPS58109444U (ja) 1982-01-20 1983-07-26 ミサワホ−ム株式会社 収塵装置
US4560675A (en) 1982-08-13 1985-12-24 Uop Inc. Adsorbent for separating fatty acids from rosin acids
US4495106A (en) 1982-08-13 1985-01-22 Uop Inc. Adsorbent and process for separating fatty acids from rosin acids
US4521343A (en) 1983-02-04 1985-06-04 Uop Inc. Process for separating fatty acids from rosin acids with phosphorus modified alumina molecular sieve
US4433195A (en) 1983-03-02 1984-02-21 Uop Inc. Separation of trans- and cis-olefins
US4524029A (en) 1983-09-22 1985-06-18 Uop Inc. Process for separating fatty acids
JPS60208940A (ja) 1984-03-31 1985-10-21 Nippon Zeon Co Ltd 長鎮不飽和脂肪酸化合物の分離精製法
US4764276A (en) 1984-07-30 1988-08-16 Advanced Separation Technologies Incorporated Device for continuous contacting of fluids and solids
US4605783A (en) 1985-03-21 1986-08-12 Uop Inc. Process for separating monoterpenes
JPH0317755Y2 (es) 1985-05-24 1991-04-15
NO157302C (no) 1985-12-19 1988-02-24 Norsk Hydro As Fremgangsmaate for fremstilling av et fiskeoljekonsentrat.
JPS6388159U (es) 1986-11-27 1988-06-08
US4720579A (en) 1986-12-18 1988-01-19 Uop Inc. Separation of citric acid from fermentation broth with a neutral polymeric adsorbent
US5068419A (en) 1986-12-18 1991-11-26 Uop Separation of an organic acid from a fermentation broth with an anionic polymeric adsorbent
US4882065A (en) 1987-12-11 1989-11-21 Uop Purification of sterols with activated carbon as adsorbent and chlorobenzene as desorbent
JPH0692595B2 (ja) 1988-02-01 1994-11-16 鐘淵化学工業株式会社 脂肪酸とトリグリセリドの分離方法
US4961881A (en) 1988-02-17 1990-10-09 Uop Process for separating triglycerides and regenerating absorbent used in said separation process
GB8819110D0 (en) 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
US4902829A (en) 1988-11-16 1990-02-20 Uop Process for the adsorptive separation of hydroxy paraffinic dicarboxylic acids from olefinic dicarboxylic acids
US5068418A (en) 1989-05-08 1991-11-26 Uop Separation of lactic acid from fermentation broth with an anionic polymeric absorbent
FR2651148B1 (fr) 1989-08-28 1992-05-07 Inst Francais Du Petrole Procede continu et dispositif de separation chromatographique d'un melange d'au moins trois constituants en trois effluents purifies au moyen de deux solvants.
FR2651149B1 (fr) 1989-08-28 1992-06-05 Inst Francais Du Petrole Procede continu et dispositif de separation chromatographique d'un melange d'au moins trois constituants en trois effluents purifies au moyen d'un seul solvant a deux temperatures et/ou a deux pressions differentes.
US5069883A (en) 1989-10-20 1991-12-03 Progress Water Technologies Corp. Device for continuous contacting of liquids and solids
US5225580A (en) 1990-08-16 1993-07-06 Uop Process for separating fatty acids and triglycerides
US5179219A (en) 1990-11-19 1993-01-12 Uop Process for separating fatty acids and triglycerides
JPH07106281B2 (ja) 1991-01-16 1995-11-15 綜研化学株式会社 多成分混合物の分離精製方法及び装置
JPH07500771A (ja) 1992-04-29 1995-01-26 アンスティテュ フランセ デュ ペトロール 圧縮ガス、超臨界流体、または臨界未満液体の存在下における、模擬移動床での混合物の分別方法および装置
JP3025590B2 (ja) 1992-10-14 2000-03-27 エーザイ株式会社 粗製物の精製法
US5719302A (en) * 1993-04-29 1998-02-17 Pronova A.S Processes for chromatographic fractionation of fatty acids and their derivatives
GB9404483D0 (en) 1994-03-08 1994-04-20 Norsk Hydro As Refining marine oil compositions
JPH08218091A (ja) * 1995-02-17 1996-08-27 Maruha Corp 高純度の高度不飽和脂肪酸およびその誘導体の製造方法
DE59610489D1 (de) 1995-08-17 2003-07-10 Hoffmann La Roche Chromatographie-Verfahren
FR2740451B1 (fr) 1995-10-27 1998-01-16 Seripharm Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
JPH09157684A (ja) 1995-12-08 1997-06-17 Chlorine Eng Corp Ltd 高度不飽和脂肪酸エステルの精製方法
US5917068A (en) 1995-12-29 1999-06-29 Eastman Chemical Company Polyunsaturated fatty acid and fatty acid ester mixtures free of sterols and phosphorus compounds
FR2754731B1 (fr) 1996-10-18 1999-07-02 Novasep Sa Perfectionnement aux procedes d'enrichissement d'isomeres optiques par lit mobile simule
GB9701705D0 (en) 1997-01-28 1997-03-19 Norsk Hydro As Purifying polyunsatured fatty acid glycerides
AU6043598A (en) * 1997-01-29 1998-08-18 Amalgamated Research, Inc. Method of displacement chromatography
JPH10310555A (ja) 1997-05-12 1998-11-24 Y M Shii:Kk 多価不飽和脂肪酸エステルの分離精製方法
US6063284A (en) 1997-05-15 2000-05-16 Em Industries, Inc. Single column closed-loop recycling with periodic intra-profile injection
FR2764822B1 (fr) 1997-06-19 1999-08-13 Novasep Methode pour optimiser le fonctionnement d'un systeme de separation des constituants d'un melange
FR2766385B1 (fr) 1997-07-24 1999-09-03 Novasep Procede pour le controle de la pression dans un systeme de separation a lit mobile simule
US5840181A (en) 1997-10-14 1998-11-24 Uop Llc Chromatographic separation of fatty acids using ultrahydrophobic silicalite
US6350890B1 (en) 1998-07-22 2002-02-26 Axiva Gmbh Method for obtaining fatty acids from biomass by combined in/situ extraction, reaction and chromatography using compressed gases
FR2781388B1 (fr) 1998-07-24 2000-08-25 Inst Francais Du Petrole Dispositif de regulation en continu de la composition d'un melange de composants et systeme de separation de constituants incorporant ce dispositif d'analyse
US6413419B1 (en) 1998-10-29 2002-07-02 Institut Francais Du Petrole Process and device for separation with variable-length chromatographic
DK1128881T3 (da) 1998-10-29 2005-10-03 Inst Francais Du Petrole Fremgangsmåde til adskillelse med kromatografiske områder med variabel længde
FR2785196B1 (fr) 1998-10-29 2000-12-15 Inst Francais Du Petrole Procede et dispositif de separation avec des zones chromatographiques a longueur variable
IT1308613B1 (it) 1999-02-17 2002-01-09 Pharmacia & Upjohn Spa Acidi grassi essenziali nella prevenzione di eventi cardiovascolari.
NO312973B1 (no) 1999-02-17 2002-07-22 Norsk Hydro As Lipase-katalysert forestring av marine oljer
JP2000280663A (ja) 1999-03-30 2000-10-10 Dainippon Printing Co Ltd Ｉｄカードおよびその判別方法
CA2311974A1 (en) 1999-06-28 2000-12-28 Nisshin Flour Milling Co., Ltd. Processes of selectively separating and purifying eicosapentaenoic and docosahexaenoic acids or their esters
WO2001033210A1 (fr) 1999-11-02 2001-05-10 Daicel Chemical Industries, Ltd Dispositif de simulation d'un lit mobile
JP4170542B2 (ja) 1999-11-18 2008-10-22 日油株式会社 高度不飽和脂肪酸誘導体の製造方法及び高純度エイコサペンタエン酸誘導体
CA2290885A1 (fr) 1999-12-02 2001-06-02 Universite De Sherbrooke Methode pour la transformation des tissus du loup marin
DK1106602T3 (da) 1999-12-09 2008-11-03 Archer Daniels Midland Co Kromatografisk simulated moving bed-oprensning af aminosyrer
WO2001050884A1 (en) 2000-01-14 2001-07-19 Baldur Hjaltason Marine lipid composition for feeding aquatic organisms
ES2324975T3 (es) 2000-01-14 2009-08-21 Epax As Metodo para el cultivo de organismos presa ricos en adh para especies acuaticas.
WO2001087452A2 (en) * 2000-05-16 2001-11-22 Purdue Research Foundation Standing wave design of single and tandem simulated moving beds for resolving multicomponent mixtures
AU2001274836A1 (en) 2000-05-16 2001-11-26 Purdue Research Foundation Standing wave design of a nine-zone smb for the recovery of a solute with intermediate affinity in a ternary mixture
WO2001087924A2 (en) 2000-05-16 2001-11-22 Purdue Research Foundation Insulin purification using simulated moving bed technology
ATE305810T1 (de) 2000-05-22 2005-10-15 Pro Aparts Investimentos E Con Fettsäure enthaltende pharmazeutische zusammensetzung die wenigstens 80 gew. epa und dha enthält
FR2810897B1 (fr) 2000-06-28 2002-10-11 Novasep Procede et dispositif de separation en lit mobile simule d'au moins un constituant dans des colonnes ayant un rapport longueur sur diametre approprie
FR2823134B1 (fr) 2001-04-10 2003-09-19 Novasep Dispositif de protection du lit chromatographique dans les colonnes chromatographiques a compression axiale dynamique
FI20010977A (fi) 2001-05-09 2002-11-10 Danisco Sweeteners Oy Kromatografinen erotusmenetelmä
US20030216543A1 (en) 2001-05-16 2003-11-20 Wang Nien-Hwa Linda Insulin purification using simulated moving bed technology
DE10151155A1 (de) 2001-10-19 2003-05-08 Nutrinova Gmbh Native PUFA-Triglyceridmischungen mit einem hohen Gehalt an mehrfach ungesättigten Fettsäuren sowie Verfahren zu deren Herstellung und deren Verwendung
FR2836230B1 (fr) 2002-02-15 2004-04-23 Novasep Protection du lit chromatographique dans les dispositifs de chromatographie a compression axiale dynamique
FR2836396B1 (fr) 2002-02-22 2004-06-18 Novasep Procede et dispositif de chromatographie avec recuperation de solvant
EP2295529B2 (en) 2002-07-11 2022-05-18 Basf As Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use
SE0202188D0 (sv) 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
KR100481663B1 (ko) 2002-09-24 2005-04-08 김희찬 중기공성 백금을 포함하는 바이오센서 및 이를 이용한글루코스 농도 측정방법
DK1549753T3 (da) 2002-10-11 2010-10-18 Nippon Suisan Kaisha Ltd Fremgangsmåde til fremstilling af mikrobielt fedt eller olie med nedsat uforsæbeligt stofindhold
FR2846252B1 (fr) 2002-10-29 2005-07-01 Novasep Procede et dispositif de chromatographie integrant une etape de concentration
NO319194B1 (no) 2002-11-14 2005-06-27 Pronova Biocare As Lipase-katalysert forestringsfremgangsmate av marine oljer
US7114844B2 (en) 2003-03-03 2006-10-03 Spx Corporation Aeration apparatus and method
ITMI20032247A1 (it) 2003-11-19 2005-05-20 Tiberio Bruzzese Interazione di derivati polari di composti insaturi con substrati inorganici
US6979402B1 (en) 2003-12-19 2005-12-27 Uop Llc Miniature actual moving bed assembly
CN103357199B (zh) 2003-12-30 2019-02-01 帝斯曼知识产权资产管理有限公司 脱气方法
MY150129A (en) 2004-04-09 2013-11-29 Archer Daniels Midland Co Method of preparing fatty acid alkyl esters from waste or recycled fatty acid stock
US20060086667A1 (en) 2004-09-13 2006-04-27 Cephalon, Inc., U.S. Corporation Methods for the separation of enantiomeric sulfinylacetamides
FR2889077B1 (fr) 2005-07-26 2007-10-12 Novasep Soc Par Actions Simpli Procede et dispositif de separation chromatographique de fractions d'un melange
ITMI20051560A1 (it) 2005-08-10 2007-02-11 Tiberio Bruzzese Composizione di acidi grassi n-3 con elevata concentrazione di epa e-o dha e contenente acidi grassi n-6
PE20070482A1 (es) 2005-08-26 2007-06-08 Ocean Nutrition Canada Ltd Metodo para remover y/o reducir esteroles a partir de aceites
US7544293B2 (en) 2005-09-26 2009-06-09 Semba Inc. Valve and process for interrupted continuous flow chromatography
BRPI0620310B1 (pt) 2005-12-16 2017-12-05 Archer-Daniels-Midland Company A method for preparing a composition enriched in compounds containing unsaturated carbon chains by simulated moving bed chromatography using an adsorbent containing silver ions
US7828978B2 (en) 2006-01-11 2010-11-09 Doug Geier Simultaneous synthesis and purification of a fatty acid monoester biodiesel fuel
FR2897277B1 (fr) 2006-02-10 2008-04-18 Novasep Soc Par Actions Simpli Procede et dispositif de separation.
FR2897238A1 (fr) 2006-02-15 2007-08-17 Novasep Soc Par Actions Simpli Procede de purification de la thaumatine
FR2898064A1 (fr) 2006-03-03 2007-09-07 Novasep Soc Par Actions Simpli Dispositif de chromatographie modulaire
FR2898283B1 (fr) 2006-03-08 2011-07-15 Novasep Procede et dispositif de separation de fractions d'un melange.
DK2006389T3 (en) 2006-04-13 2017-08-28 Nippon Suisan Kaisha Ltd Process for preparing concentrated polyunsaturated fatty acid oil
WO2008149177A2 (en) 2006-05-05 2008-12-11 Natural Asa Marine lipid compositions and uses thereof
WO2007144476A1 (fr) 2006-06-16 2007-12-21 Groupe Novasep Procede de separation sequence multicolonnes
WO2007147554A2 (en) 2006-06-19 2007-12-27 K.D. Pharma Bexbach Gmbh Improved cromatography process for recovering a substance or a group of substances from a mixture
US8877465B2 (en) 2006-07-05 2014-11-04 Photonz Corporation Limited Production of ultrapure EPA and polar lipids from largely heterotrophic culture
WO2008025887A1 (fr) 2006-08-28 2008-03-06 Novasep Procede d'enrichissement d'un ou plusieurs composes d'un melange utilisant une phase mobile liquide contenant un gaz
FR2911793B1 (fr) 2007-01-26 2010-07-30 Novasep Procede de separation par chromatographie
DE502007004854D1 (de) 2007-04-17 2010-10-07 Max Planck Gesellschaft Verfahren und Vorrichtung zur chromatographischen Trennung von Komponenten mit teilweiser Rückführung von Gemischfraktionen
US7901581B2 (en) * 2007-06-15 2011-03-08 Ge Healthcare Bio-Sciences Ab Chromatography method
CA2692355C (en) 2007-06-29 2018-09-11 Martek Biosciences Corporation Production and purification of esters of polyunsaturated fatty acids
US20100197785A1 (en) 2007-07-25 2010-08-05 Epax As Omega-3 fatty acid fortified composition
FR2919200B1 (fr) 2007-07-27 2009-10-30 Novasep Procede de cristallisation en continu
EP2172558B1 (en) 2007-07-30 2017-07-19 Nippon Suisan Kaisha, Ltd. Method for production of epa-enriched oil and dha-enriched oil
US20100331559A1 (en) 2008-02-21 2010-12-30 Dow Global Technologies Inc. Separation of natural oil-derived aldehydes or hydroxy methyl esters using process chromatography
FR2929533B1 (fr) 2008-04-03 2010-04-30 Novasep Procede de separation multicolonnes a gradient.
KR101357298B1 (ko) 2008-06-20 2014-01-28 에이케이 앤 엠엔 바이오팜 주식회사 오메가-3계 고도불포화 지방산의 고순도 정제방법
WO2010018422A1 (en) 2008-08-14 2010-02-18 Novasep Process for the enrichment of isotopes
CN110538148A (zh) 2009-03-09 2019-12-06 巴斯夫股份公司 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途
EP2519332B1 (en) 2009-12-30 2014-03-05 BASF Pharma (Callanish) Limited Simulated moving bed chromatographic separation process for the purification of polyunsaturated fatty acids
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process

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GB201111601D0 (en) 2011-08-24
EP2613858A1 (en) 2013-07-17
WO2013005046A1 (en) 2013-01-10
KR101594722B1 (ko) 2016-02-16
JP2014518312A (ja) 2014-07-28
PE20142016A1 (es) 2014-12-30
BR112014000163A2 (pt) 2017-02-07
EP2613858B1 (en) 2015-03-18
AU2012280065B2 (en) 2015-07-09
CN103764242B (zh) 2015-07-15
CA2815296C (en) 2015-02-10
JP2017020031A (ja) 2017-01-26
US20140194636A1 (en) 2014-07-10
US9370730B2 (en) 2016-06-21
AU2012280065A1 (en) 2013-05-09
ES2536911T3 (es) 2015-05-29
CN103764242A (zh) 2014-04-30
CA2815296A1 (en) 2013-01-10
KR20140034920A (ko) 2014-03-20

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