CL2013000580A1 - Metodo de regeneracion o reparacion muscular que comprende administrar un antagonista del receptor de acido retinoico gama (rary); metodo para la induccion o estimulacion de diferenciacion miogenica de celulas madre; composicion que comprende celulas madre mesenquimales; composicion farmaceutica; kit. - Google Patents

Metodo de regeneracion o reparacion muscular que comprende administrar un antagonista del receptor de acido retinoico gama (rary); metodo para la induccion o estimulacion de diferenciacion miogenica de celulas madre; composicion que comprende celulas madre mesenquimales; composicion farmaceutica; kit.

Info

Publication number
CL2013000580A1
CL2013000580A1 CL2013000580A CL2013000580A CL2013000580A1 CL 2013000580 A1 CL2013000580 A1 CL 2013000580A1 CL 2013000580 A CL2013000580 A CL 2013000580A CL 2013000580 A CL2013000580 A CL 2013000580A CL 2013000580 A1 CL2013000580 A1 CL 2013000580A1
Authority
CL
Chile
Prior art keywords
stem cells
composition
rary
stimulation
administering
Prior art date
Application number
CL2013000580A
Other languages
English (en)
Spanish (es)
Inventor
Masahiro Iwamoto
Maurizio Pacifici
Original Assignee
Univ Jefferson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45773490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013000580(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Jefferson filed Critical Univ Jefferson
Publication of CL2013000580A1 publication Critical patent/CL2013000580A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CL2013000580A 2010-09-01 2013-02-28 Metodo de regeneracion o reparacion muscular que comprende administrar un antagonista del receptor de acido retinoico gama (rary); metodo para la induccion o estimulacion de diferenciacion miogenica de celulas madre; composicion que comprende celulas madre mesenquimales; composicion farmaceutica; kit. CL2013000580A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37899610P 2010-09-01 2010-09-01

Publications (1)

Publication Number Publication Date
CL2013000580A1 true CL2013000580A1 (es) 2013-07-12

Family

ID=45773490

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013000580A CL2013000580A1 (es) 2010-09-01 2013-02-28 Metodo de regeneracion o reparacion muscular que comprende administrar un antagonista del receptor de acido retinoico gama (rary); metodo para la induccion o estimulacion de diferenciacion miogenica de celulas madre; composicion que comprende celulas madre mesenquimales; composicion farmaceutica; kit.

Country Status (20)

Country Link
US (6) US9789074B2 (enExample)
EP (3) EP4066826B1 (enExample)
JP (1) JP5986570B2 (enExample)
CN (2) CN111773213B (enExample)
AU (1) AU2011296080B2 (enExample)
BR (1) BR112013004685B1 (enExample)
CA (1) CA2809374C (enExample)
CL (1) CL2013000580A1 (enExample)
CO (1) CO6680694A2 (enExample)
DK (2) DK3721880T3 (enExample)
EA (1) EA026251B1 (enExample)
ES (3) ES2823234T3 (enExample)
HU (2) HUE051664T2 (enExample)
IL (1) IL224973B (enExample)
MX (2) MX361414B (enExample)
NZ (1) NZ607547A (enExample)
PL (2) PL3721880T3 (enExample)
PT (1) PT2613776T (enExample)
WO (1) WO2012030919A2 (enExample)
ZA (1) ZA201301536B (enExample)

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US11963964B2 (en) 2011-06-16 2024-04-23 President And Fellows Of Harvard College Small molecules for mouse satellite cell proliferation
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US9784665B1 (en) * 2014-12-29 2017-10-10 Flagship Biosciences, Inc. Methods for quantitative assessment of muscle fibers in muscular dystrophy
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CA3025854A1 (en) 2016-06-08 2017-12-14 Clementia Pharmaceuticals Inc. Methods for treating heterotopic ossification
EP3541380B1 (en) 2016-11-16 2021-12-15 Clementia Pharmaceuticals Inc. Methods for treating multiple osteochondroma (mo)
CA3019069A1 (en) * 2018-04-02 2019-10-02 Hubit Genomix, Inc. Prophylactic and/or therapeutic drug for diabetic nephropathy
US11135236B2 (en) * 2018-04-10 2021-10-05 Northwestern University Retinoic acid receptor gamma agonists to attenuate anthracycline-induced cardiotoxicity
GB201907647D0 (en) * 2019-05-30 2019-07-17 King S College London Therapeutic methods
FR3112684B1 (fr) * 2020-07-24 2022-08-12 Univ Grenoble Alpes Composés pour le traitement de l’hémophilie
CN116891497B (zh) * 2022-04-02 2025-12-16 上海旭成医药科技有限公司 视黄酸受体激动剂、其制备方法、中间体、药物组合物和应用
US20250367183A1 (en) * 2022-06-16 2025-12-04 Institute Of Zoology, Chinese Academy Of Sciences Substance for promoting regeneration and repair of organs of mammals and use thereof

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Also Published As

Publication number Publication date
DK3721880T3 (da) 2022-05-09
US20140303223A1 (en) 2014-10-09
US20200069620A1 (en) 2020-03-05
CA2809374C (en) 2021-02-23
ZA201301536B (en) 2015-06-24
US20250108022A1 (en) 2025-04-03
US20180000762A1 (en) 2018-01-04
MX2018015032A (es) 2021-12-08
CN111773213A (zh) 2020-10-16
CO6680694A2 (es) 2013-05-31
US12023312B2 (en) 2024-07-02
ES2975123T3 (es) 2024-07-03
PT2613776T (pt) 2020-10-21
CN103200937B (zh) 2020-07-03
WO2012030919A3 (en) 2012-07-05
PL2613776T3 (pl) 2021-01-11
US10292954B2 (en) 2019-05-21
PL3721880T3 (pl) 2022-05-23
US11433039B2 (en) 2022-09-06
AU2011296080A1 (en) 2013-03-14
ES2823234T3 (es) 2021-05-06
BR112013004685A2 (pt) 2019-04-24
DK2613776T3 (da) 2020-10-19
EP4066826A1 (en) 2022-10-05
AU2011296080B2 (en) 2014-12-04
IL224973B (en) 2018-06-28
EP2613776A2 (en) 2013-07-17
CA2809374A1 (en) 2012-03-08
EP4066826C0 (en) 2024-03-06
CN103200937A (zh) 2013-07-10
US20140363402A1 (en) 2014-12-11
US9789074B2 (en) 2017-10-17
BR112013004685B1 (pt) 2021-09-21
NZ607547A (en) 2015-06-26
JP2013536855A (ja) 2013-09-26
EP2613776A4 (en) 2014-03-12
EP2613776B1 (en) 2020-07-29
MX361414B (es) 2018-12-05
EA026251B1 (ru) 2017-03-31
EP3721880A1 (en) 2020-10-14
HUE059024T2 (hu) 2022-10-28
US20230201146A1 (en) 2023-06-29
MX2013002275A (es) 2013-05-22
HUE051664T2 (hu) 2021-03-29
EA201370051A1 (ru) 2014-03-31
JP5986570B2 (ja) 2016-09-06
WO2012030919A2 (en) 2012-03-08
EP3721880B1 (en) 2022-02-02
CN111773213B (zh) 2023-02-24
EP4066826B1 (en) 2024-03-06
US9314439B2 (en) 2016-04-19
ES2912593T3 (es) 2022-05-26

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