CL2011000792A1 - Acido nucleico aislado que codifica mutante del factor de crecimiento de fibroblastos 21 (fgf21); vector; celula huesped; fgf21 mutante; proceso de produccion; composicion farmaceutica que lo comprende; y metodo para tratar un trastorno metabolico. - Google Patents
Acido nucleico aislado que codifica mutante del factor de crecimiento de fibroblastos 21 (fgf21); vector; celula huesped; fgf21 mutante; proceso de produccion; composicion farmaceutica que lo comprende; y metodo para tratar un trastorno metabolico.Info
- Publication number
- CL2011000792A1 CL2011000792A1 CL2011000792A CL2011000792A CL2011000792A1 CL 2011000792 A1 CL2011000792 A1 CL 2011000792A1 CL 2011000792 A CL2011000792 A CL 2011000792A CL 2011000792 A CL2011000792 A CL 2011000792A CL 2011000792 A1 CL2011000792 A1 CL 2011000792A1
- Authority
- CL
- Chile
- Prior art keywords
- fgf21
- mutant
- treat
- vector
- nucleic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000018233 Fibroblast Growth Factor Human genes 0.000 title abstract 2
- 108050007372 Fibroblast Growth Factor Proteins 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 title abstract 2
- 229940126864 fibroblast growth factor Drugs 0.000 title abstract 2
- 208000030159 metabolic disease Diseases 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000003973 Fibroblast growth factor 21 Human genes 0.000 title 2
- 108090000376 Fibroblast growth factor 21 Proteins 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19576108P | 2008-10-10 | 2008-10-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011000792A1 true CL2011000792A1 (es) | 2011-08-26 |
Family
ID=41571715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011000792A CL2011000792A1 (es) | 2008-10-10 | 2011-04-08 | Acido nucleico aislado que codifica mutante del factor de crecimiento de fibroblastos 21 (fgf21); vector; celula huesped; fgf21 mutante; proceso de produccion; composicion farmaceutica que lo comprende; y metodo para tratar un trastorno metabolico. |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9279013B2 (enExample) |
| EP (1) | EP2358749B1 (enExample) |
| JP (2) | JP5878757B2 (enExample) |
| KR (1) | KR101651703B1 (enExample) |
| CN (1) | CN102625811B (enExample) |
| AU (1) | AU2009302318A1 (enExample) |
| CA (1) | CA2739615C (enExample) |
| CL (1) | CL2011000792A1 (enExample) |
| CO (1) | CO6362020A2 (enExample) |
| CR (1) | CR20110245A (enExample) |
| EA (2) | EA032727B1 (enExample) |
| IL (1) | IL212061A0 (enExample) |
| MA (1) | MA32771B1 (enExample) |
| MX (1) | MX341149B (enExample) |
| NZ (1) | NZ592009A (enExample) |
| PE (1) | PE20120021A1 (enExample) |
| SG (1) | SG195542A1 (enExample) |
| TN (1) | TN2011000161A1 (enExample) |
| UA (1) | UA105016C2 (enExample) |
| WO (1) | WO2010042747A2 (enExample) |
| ZA (1) | ZA201103356B (enExample) |
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| US20110195077A1 (en) * | 2010-01-29 | 2011-08-11 | Novartis Ag | Methods and compositions using fgf23 fusion ppolypeptides |
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- 2009-10-08 CA CA2739615A patent/CA2739615C/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2011003788A (es) | 2011-08-03 |
| NZ592009A (en) | 2012-11-30 |
| JP2012504965A (ja) | 2012-03-01 |
| WO2010042747A3 (en) | 2010-06-17 |
| EP2358749B1 (en) | 2018-07-18 |
| UA105016C2 (uk) | 2014-04-10 |
| CN102625811B (zh) | 2016-09-21 |
| MA32771B1 (fr) | 2011-11-01 |
| SG195542A1 (en) | 2013-12-30 |
| EA201990619A1 (ru) | 2019-07-31 |
| EA032727B1 (ru) | 2019-07-31 |
| CA2739615A1 (en) | 2010-04-15 |
| EA201100516A1 (ru) | 2011-10-31 |
| US9279013B2 (en) | 2016-03-08 |
| PE20120021A1 (es) | 2012-02-10 |
| TN2011000161A1 (en) | 2012-12-17 |
| CA2739615C (en) | 2017-12-05 |
| EP2358749A2 (en) | 2011-08-24 |
| KR20110093790A (ko) | 2011-08-18 |
| ZA201103356B (en) | 2012-02-29 |
| US20110195895A1 (en) | 2011-08-11 |
| JP5878757B2 (ja) | 2016-03-08 |
| AU2009302318A1 (en) | 2010-04-15 |
| CR20110245A (es) | 2011-08-29 |
| MX341149B (es) | 2016-08-09 |
| CO6362020A2 (es) | 2012-01-20 |
| IL212061A0 (en) | 2011-06-30 |
| KR101651703B1 (ko) | 2016-08-26 |
| US20160244497A1 (en) | 2016-08-25 |
| JP2015165801A (ja) | 2015-09-24 |
| WO2010042747A2 (en) | 2010-04-15 |
| CN102625811A (zh) | 2012-08-01 |
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