CL2007003201A1 - Composicion farmaceutica liquida que comprende un derivado de ciclodextrina eterificada y un bencimidazol sustituido, donde el derivado de ciclodextrina se selecciona de eter de alfa, beta y gama-ciclodextrina; y uso para el tratamiento de insuficien - Google Patents
Composicion farmaceutica liquida que comprende un derivado de ciclodextrina eterificada y un bencimidazol sustituido, donde el derivado de ciclodextrina se selecciona de eter de alfa, beta y gama-ciclodextrina; y uso para el tratamiento de insuficienInfo
- Publication number
- CL2007003201A1 CL2007003201A1 CL200703201A CL2007003201A CL2007003201A1 CL 2007003201 A1 CL2007003201 A1 CL 2007003201A1 CL 200703201 A CL200703201 A CL 200703201A CL 2007003201 A CL2007003201 A CL 2007003201A CL 2007003201 A1 CL2007003201 A1 CL 2007003201A1
- Authority
- CL
- Chile
- Prior art keywords
- cyclodextrine
- derivative
- eterified
- bencimidazol
- efa
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06123567A EP1920785A1 (en) | 2006-11-07 | 2006-11-07 | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007003201A1 true CL2007003201A1 (es) | 2008-04-11 |
Family
ID=37735786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200703201A CL2007003201A1 (es) | 2006-11-07 | 2007-11-06 | Composicion farmaceutica liquida que comprende un derivado de ciclodextrina eterificada y un bencimidazol sustituido, donde el derivado de ciclodextrina se selecciona de eter de alfa, beta y gama-ciclodextrina; y uso para el tratamiento de insuficien |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US9107952B2 (es) |
| EP (3) | EP1920785A1 (es) |
| JP (1) | JP5565794B2 (es) |
| KR (1) | KR101434324B1 (es) |
| CN (3) | CN104800153A (es) |
| AR (1) | AR063587A1 (es) |
| AU (1) | AU2007316712B2 (es) |
| BR (1) | BRPI0718541B8 (es) |
| CA (1) | CA2668733C (es) |
| CL (1) | CL2007003201A1 (es) |
| CY (1) | CY1115710T1 (es) |
| DK (2) | DK2789349T3 (es) |
| ES (2) | ES2649718T3 (es) |
| HR (1) | HRP20140873T1 (es) |
| HU (1) | HUE035821T2 (es) |
| MX (1) | MX2009004767A (es) |
| NZ (1) | NZ577067A (es) |
| PL (2) | PL2789349T3 (es) |
| PT (1) | PT2089060E (es) |
| SI (1) | SI2089060T1 (es) |
| TW (1) | TWI432425B (es) |
| WO (1) | WO2008055871A1 (es) |
| ZA (1) | ZA200902085B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004011512B4 (de) | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
| US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
| EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
| KR20110089851A (ko) * | 2008-11-25 | 2011-08-09 | 베링거잉겔하임베트메디카게엠베하 | 비대 심근병증의 치료를 위한 포스포디에스테라제 타입 Ⅲ（ＰＤＥ Ⅲ） 억제제 또는 Ｃａ２＋―감작제 |
| NL1037569C2 (en) * | 2009-12-18 | 2011-06-21 | Eurovet Animal Health B V | Crystalline pimobendan, process for the preparation thereof, pharmaceutical composition and use. |
| US10052345B2 (en) | 2010-10-19 | 2018-08-21 | University Of Miami | Assays, methods and kits for predicting renal disease and personalized treatment strategies |
| EP2825159B1 (en) | 2012-03-15 | 2022-06-22 | Boehringer Ingelheim Vetmedica GmbH | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
| EP4299121A2 (en) | 2012-04-13 | 2024-01-03 | L&F Research LLC | Method of using cyclodextrin |
| WO2015007759A1 (en) * | 2013-07-19 | 2015-01-22 | Boehringer Ingelheim Vetmedica Gmbh | Etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition |
| KR102455648B1 (ko) | 2013-07-19 | 2022-10-19 | 베링거잉겔하임베트메디카게엠베하 | 보존된 에테르화된 사이클로덱스트린 유도체 함유 액체 수성 약제학적 조성물 |
| BR112016011111B1 (pt) | 2013-12-04 | 2022-11-16 | Boehringer Ingelheim Vetmedica Gmbh | Composições farmacêuticas aprimoradas de pimobendan |
| KR102429646B1 (ko) * | 2016-03-14 | 2022-08-04 | 산텐 세이야꾸 가부시키가이샤 | 메글루민 또는 그의 염을 포함하는 방부제 |
| US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
| KR101829685B1 (ko) * | 2016-07-28 | 2018-02-19 | 씨제이헬스케어 주식회사 | 안정성 및 용해도가 개선된 주사용 조성물 |
| CN106729723A (zh) * | 2016-11-21 | 2017-05-31 | 青岛农业大学 | 一种含匹莫苯丹的药物组合物及其制备方法 |
| KR102034760B1 (ko) | 2018-12-31 | 2019-10-22 | 지앤에스건설 주식회사 | 긴장시스템을 도입한 일체형 현장타설 말뚝 시공방법이 적용된 구조 |
| CN114599353A (zh) * | 2019-10-23 | 2022-06-07 | 皮埃蒙特动物健康公司 | 匹莫苯制剂及其使用方法 |
| WO2022073954A1 (en) | 2020-10-08 | 2022-04-14 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan in the anaesthesia of non-human mammals |
| KR102546153B1 (ko) | 2022-08-01 | 2023-06-20 | 함정아 | 횡방향 지지력이 증가된 교량용 말뚝 및 그 시공방법 |
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2006
- 2006-11-07 EP EP06123567A patent/EP1920785A1/en not_active Ceased
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- 2007-11-05 PT PT78222080T patent/PT2089060E/pt unknown
- 2007-11-05 BR BRPI0718541A patent/BRPI0718541B8/pt active IP Right Grant
- 2007-11-05 EP EP14171537.5A patent/EP2789349B1/en active Active
- 2007-11-05 CN CN201510090080.9A patent/CN104800153A/zh active Pending
- 2007-11-05 SI SI200731512T patent/SI2089060T1/sl unknown
- 2007-11-05 DK DK14171537.5T patent/DK2789349T3/da active
- 2007-11-05 MX MX2009004767A patent/MX2009004767A/es active IP Right Grant
- 2007-11-05 HU HUE14171537A patent/HUE035821T2/hu unknown
- 2007-11-05 ES ES14171537.5T patent/ES2649718T3/es active Active
- 2007-11-05 EP EP07822208.0A patent/EP2089060B1/en active Active
- 2007-11-05 CN CNA2007800414452A patent/CN101534864A/zh active Pending
- 2007-11-05 CN CN201510090079.6A patent/CN104688680A/zh active Pending
- 2007-11-05 CA CA2668733A patent/CA2668733C/en active Active
- 2007-11-05 JP JP2009535699A patent/JP5565794B2/ja active Active
- 2007-11-05 WO PCT/EP2007/061879 patent/WO2008055871A1/en active Application Filing
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- 2007-11-05 DK DK07822208.0T patent/DK2089060T3/da active
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