CL2007002923A1 - Metodo para el tratamiento, prevencion o manejo de una enfermedad asociada con una mutacion sin sentido tal como cancer, diabetes o enfermedad pulmonar, que consiste en administrar a un paciente una cantidad efectiva de acido 3-[5-(2-fluoro-fenil)-[1 - Google Patents

Metodo para el tratamiento, prevencion o manejo de una enfermedad asociada con una mutacion sin sentido tal como cancer, diabetes o enfermedad pulmonar, que consiste en administrar a un paciente una cantidad efectiva de acido 3-[5-(2-fluoro-fenil)-[1

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Publication number
CL2007002923A1
CL2007002923A1 CL200702923A CL2007002923A CL2007002923A1 CL 2007002923 A1 CL2007002923 A1 CL 2007002923A1 CL 200702923 A CL200702923 A CL 200702923A CL 2007002923 A CL2007002923 A CL 2007002923A CL 2007002923 A1 CL2007002923 A1 CL 2007002923A1
Authority
CL
Chile
Prior art keywords
mutation
diabetes
fluoro
cancer
managing
Prior art date
Application number
CL200702923A
Other languages
English (en)
Inventor
Hirawat Y Langdon Mille Sarnit
Original Assignee
Ptc Therapeutics Inc Soc Organ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39102963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2007002923(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ptc Therapeutics Inc Soc Organ filed Critical Ptc Therapeutics Inc Soc Organ
Publication of CL2007002923A1 publication Critical patent/CL2007002923A1/es

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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/02—Inorganic compounds
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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CL200702923A 2006-10-12 2007-10-11 Metodo para el tratamiento, prevencion o manejo de una enfermedad asociada con una mutacion sin sentido tal como cancer, diabetes o enfermedad pulmonar, que consiste en administrar a un paciente una cantidad efectiva de acido 3-[5-(2-fluoro-fenil)-[1 CL2007002923A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85145006P 2006-10-12 2006-10-12

Publications (1)

Publication Number Publication Date
CL2007002923A1 true CL2007002923A1 (es) 2008-06-06

Family

ID=39102963

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200702923A CL2007002923A1 (es) 2006-10-12 2007-10-11 Metodo para el tratamiento, prevencion o manejo de una enfermedad asociada con una mutacion sin sentido tal como cancer, diabetes o enfermedad pulmonar, que consiste en administrar a un paciente una cantidad efectiva de acido 3-[5-(2-fluoro-fenil)-[1

Country Status (24)

Country Link
US (7) US9226919B2 (es)
EP (2) EP2460520B1 (es)
JP (4) JP2010506840A (es)
KR (4) KR20090074231A (es)
CN (2) CN101553226B (es)
AU (1) AU2007308067B2 (es)
BR (2) BRPI0719276A2 (es)
CA (1) CA2675518C (es)
CL (1) CL2007002923A1 (es)
DK (1) DK2073805T3 (es)
ES (1) ES2538359T3 (es)
HK (2) HK1136214A1 (es)
HR (1) HRP20150590T1 (es)
IL (2) IL198147A (es)
MX (1) MX2009003909A (es)
NO (1) NO342061B1 (es)
PE (4) PE20080982A1 (es)
PL (1) PL2073805T3 (es)
PT (1) PT2073805E (es)
RS (1) RS54025B1 (es)
RU (1) RU2462247C2 (es)
SI (1) SI2073805T1 (es)
TW (1) TWI405570B (es)
WO (1) WO2008045566A1 (es)

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ES2624610T3 (es) 2003-04-11 2017-07-17 Ptc Therapeutics, Inc. Compuestos de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
CN101505739A (zh) * 2006-03-30 2009-08-12 Ptc医疗公司 由具有无义突变的dna生产功能蛋白的方法以及相关疾病的治疗
DK2073805T3 (da) 2006-10-12 2015-06-15 Ptc Therapeutics Inc Fremgangsmåder til dosering af en oralt aktiv 1,2,4-oxadiazol til terapi for suppression af nonsens-mutation
ES2841809T3 (es) 2011-06-03 2021-07-09 Eisai R&D Man Co Ltd Biomarcadores para pronosticar y evaluar el grado de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib
CN106455571A (zh) * 2014-03-06 2017-02-22 Ptc医疗公司 1,2,4‑噁二唑苯甲酸的药物组合物和盐
ES2926687T3 (es) 2014-08-28 2022-10-27 Eisai R&D Man Co Ltd Derivado de quinolina muy puro y método para su producción
HUE064614T2 (hu) 2015-02-25 2024-04-28 Eisai R&D Man Co Ltd Eljárás egy kinolin-származék keserû ízének elnyomására
AU2016279474B2 (en) 2015-06-16 2021-09-09 Eisai R&D Management Co., Ltd. Anticancer agent
AR106530A1 (es) 2015-10-30 2018-01-24 Ptc Therapeutics Inc Métodos para tratar epilepsia
TWI801438B (zh) 2017-10-19 2023-05-11 中國大陸商軒竹（北京）醫藥科技有限公司 抗菌胺基糖苷類似物之合成
EP3713934B1 (en) 2017-11-23 2022-04-13 Universita' degli Studi di Palermo Oxadiazole derivatives for the treatment of genetic diseases due to nonsense mutations
KR102378381B1 (ko) * 2021-08-23 2022-03-24 라이보텍(주) 넌센스-매개 mRNA 분해를 억제하기 위한 화합물
WO2022177269A1 (ko) * 2021-02-16 2022-08-25 라이보텍(주) 넌센스-매개 mrna 분해를 억제하기 위한 화합물
WO2022241030A1 (en) * 2021-05-11 2022-11-17 Regenxbio Inc. Treatment of duchenne muscular dystrophy and combinations thereof
KR102665711B1 (ko) * 2021-12-21 2024-05-14 재단법인 아산사회복지재단 Ras 활성도를 이용한 신경섬유종증 치료제에 대한 감수성 예측용 바이오마커 조성물 및 Ras 활성 억제제를 포함하는 신경섬유종증 예방 또는 치료용 약학적 조성물

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EP2460520A1 (en) 2012-06-06
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US9226919B2 (en) 2016-01-05
US20170049752A1 (en) 2017-02-23
PE20212245A1 (es) 2021-11-24
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US20170304275A1 (en) 2017-10-26
TW200820968A (en) 2008-05-16
JP2010506840A (ja) 2010-03-04
WO2008045566B1 (en) 2008-06-19
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AU2007308067A1 (en) 2008-04-17
KR20160128468A (ko) 2016-11-07
JP6129713B2 (ja) 2017-05-17
CA2675518C (en) 2017-11-14
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CA2675518A1 (en) 2008-04-17
US20080114039A1 (en) 2008-05-15
CN101553226A (zh) 2009-10-07
US9737513B2 (en) 2017-08-22
US20190099405A1 (en) 2019-04-04
SI2073805T1 (sl) 2015-10-30
PT2073805E (pt) 2015-07-13
IL198147A (en) 2016-02-29
BRPI0719276A2 (pt) 2014-04-29
JP2016029078A (ja) 2016-03-03
EP2073805B1 (en) 2015-03-04
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CN101553226B (zh) 2015-05-13
MX2009003909A (es) 2009-05-25
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KR20170100072A (ko) 2017-09-01
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WO2008045566A1 (en) 2008-04-17
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CN103211766B (zh) 2015-03-11
AU2007308067B2 (en) 2013-05-30
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JP2014058533A (ja) 2014-04-03
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US9522137B2 (en) 2016-12-20
EP2073805A1 (en) 2009-07-01
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