CH675724A5 - - Google Patents

Download PDF

Info

Publication number
CH675724A5
CH675724A5 CH206/88A CH20688A CH675724A5 CH 675724 A5 CH675724 A5 CH 675724A5 CH 206/88 A CH206/88 A CH 206/88A CH 20688 A CH20688 A CH 20688A CH 675724 A5 CH675724 A5 CH 675724A5
Authority
CH
Switzerland
Prior art keywords
formula
alk
oxidation
alkyl
group
Prior art date
Application number
CH206/88A
Other languages
German (de)
English (en)
Inventor
James P Kutney
Lewis S L Choi
Jun Nakano
Hiroki Tsukamoto
Camille A Boulet
Michael Mchugh
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of CH675724A5 publication Critical patent/CH675724A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CH206/88A 1987-01-22 1988-01-21 CH675724A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000527897A CA1341261C (fr) 1987-01-22 1987-01-22 Procede pour la synthese de 3',4'-anhydrovinblastine, de la vinblastine et de la vincristine

Publications (1)

Publication Number Publication Date
CH675724A5 true CH675724A5 (fr) 1990-10-31

Family

ID=4134803

Family Applications (1)

Application Number Title Priority Date Filing Date
CH206/88A CH675724A5 (fr) 1987-01-22 1988-01-21

Country Status (11)

Country Link
JP (1) JPH0613531B2 (fr)
CA (1) CA1341261C (fr)
CH (1) CH675724A5 (fr)
DE (1) DE3801450C2 (fr)
FR (1) FR2611202A1 (fr)
GB (1) GB2204036B (fr)
IL (1) IL85154A (fr)
IT (1) IT1215751B (fr)
NL (1) NL8800134A (fr)
SE (1) SE467874B (fr)
ZA (1) ZA88408B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
CA1341262C (fr) * 1987-08-06 2001-06-26 Camille A. Boulet Nouveau procede de synthese de 3',4'-anhydrovinblastine de la vinblastine et de la vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5037977A (en) * 1988-08-11 1991-08-06 Mitsui Petrochemical Industries Ltd. Method for production of dimeric alkaloids
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
HU209687B (en) * 1989-03-04 1994-10-28 Mitsui Petrochemical Ind Process for producing bisz-indole-alkaloids
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation
CN103936769B (zh) * 2014-04-30 2016-10-05 淮海工学院 一种制备高光学纯脱水长春碱的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (fr) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
GB1551054A (en) * 1976-03-04 1979-08-22 Atta Ur Rahman Syntheses of vinblastine vincristine and vinrosidine
FR2358412A1 (fr) * 1976-07-13 1978-02-10 Parcor Procede de preparation de la vincamine et d'alcaloides apparentes

Also Published As

Publication number Publication date
IT8819156A0 (it) 1988-01-21
GB8801296D0 (en) 1988-02-17
GB2204036B (en) 1991-03-27
GB2204036A (en) 1988-11-02
FR2611202A1 (fr) 1988-08-26
IL85154A0 (en) 1988-06-30
JPH0613531B2 (ja) 1994-02-23
SE8800170L (sv) 1988-07-23
CA1341261C (fr) 2001-06-26
SE8800170D0 (sv) 1988-01-20
FR2611202B1 (fr) 1994-08-19
JPH01131187A (ja) 1989-05-24
DE3801450C2 (de) 1999-02-25
NL8800134A (nl) 1988-08-16
IL85154A (en) 1992-08-18
ZA88408B (en) 1989-04-26
IT1215751B (it) 1990-02-22
SE467874B (sv) 1992-09-28
DE3801450A1 (de) 1988-08-18

Similar Documents

Publication Publication Date Title
Nozaki et al. Antitumour triterpenes of Maytenus diversifolia
DE2606265A1 (de) Camptothecin-derivate
DE3010544A1 (de) 1h-pyrrolo eckige klammer auf 2,1-c eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin- 2-acrylsaeureamid-verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2622894A1 (de) Verfahren zur synthese eines dimeren mit einer indoleinheit und einer dihydroindoleinheit
DE2723209A1 (de) Tetracyclische pyridin- oder pyrrolderivate
DD148517A5 (de) Verfahren zur herstellung von 6-oxodecahydrochinolinen
CH625530A5 (fr)
DD143075A5 (de) Verfahren zur herstellung von 4-desacetyl-vincaleucoblastin-c tief 3-carbonsaeurehydraziden
DE3801450C2 (de) Verfahren für die Herstellung von Dimeralkaloidverbindungen, insbesondere von 3', 4'-Dihydrovinblastin, Vinblastin und Vincristin
Baldé et al. Spermacoceine, a bis-indole alkaloid from Borreria verticillata
EP0130140B1 (fr) Bêta-carbolines, procédé pour leur préparation et leur utilisation comme médicaments
DE2155578C3 (de) Verfahren zur Herstellung von 8,9-Didehydro- 10-alkoxy-ergolenderivaten
DE1947455A1 (de) Neue 19-Hydroxy-3-aza-A-homo-steroide und ein Verfahren zu deren Herstellung
DE69330693T2 (de) Antitumor 5,8-Dihydrodiazaanthracene
Takatsu et al. The synthesis of lupin alkaloids. II. A formal synthesis of (±)-sparteine
DE3826412A1 (de) Verfahren fuer die synthese von vinblastin und vincristin
DE2453649C3 (de) Verfahren zur Herstellung von Coformycin und Zwischenprodukte zu seiner Herstellung
CH639390A5 (de) Verfahren zur herstellung von alkaloiden vom leurosin-typ.
CH617197A5 (fr)
DE1232577B (de) Verfahren zur Herstellung von delta 4,9-3-Oxo-11beta-hydroperoxy-19-nor-steroiden
DE2338838A1 (de) 9h-pyrido eckige klammer auf 3,4 eckige klammer zu indol-derivate, verfahren zu deren herstellung und deren verwendung
CH512500A (de) Verfahren zur Herstellung von Phenazin-Derivaten
Ujváry et al. Partial synthesis of 3-O-vanilloylveracevine, an insecticidal alkaloid from Schoenocaulon officinale
DE69111835T2 (de) Hydroxycarbonylderivate und Verfahren zu ihrer Herstellung.
DE1933134A1 (de) Verfahren zur Herstellung von Isochinuclidinalkaloiden

Legal Events

Date Code Title Description
PL Patent ceased