IT1215751B - Procedimento di sintesi di vinblastina e vincristina. - Google Patents

Procedimento di sintesi di vinblastina e vincristina.

Info

Publication number
IT1215751B
IT1215751B IT8819156A IT1915688A IT1215751B IT 1215751 B IT1215751 B IT 1215751B IT 8819156 A IT8819156 A IT 8819156A IT 1915688 A IT1915688 A IT 1915688A IT 1215751 B IT1215751 B IT 1215751B
Authority
IT
Italy
Prior art keywords
vinblastin
vincristine
synthesis procedure
synthesis
procedure
Prior art date
Application number
IT8819156A
Other languages
English (en)
Other versions
IT8819156A0 (it
Inventor
Camille A Boulet
James P Kutney
Michael Mchugh
Lewis S L Choi
Jun Nakano
Hiroki Tsukamoto
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of IT8819156A0 publication Critical patent/IT8819156A0/it
Application granted granted Critical
Publication of IT1215751B publication Critical patent/IT1215751B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT8819156A 1987-01-22 1988-01-21 Procedimento di sintesi di vinblastina e vincristina. IT1215751B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000527897A CA1341261C (en) 1987-01-22 1987-01-22 Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Publications (2)

Publication Number Publication Date
IT8819156A0 IT8819156A0 (it) 1988-01-21
IT1215751B true IT1215751B (it) 1990-02-22

Family

ID=4134803

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8819156A IT1215751B (it) 1987-01-22 1988-01-21 Procedimento di sintesi di vinblastina e vincristina.

Country Status (11)

Country Link
JP (1) JPH0613531B2 (it)
CA (1) CA1341261C (it)
CH (1) CH675724A5 (it)
DE (1) DE3801450C2 (it)
FR (1) FR2611202A1 (it)
GB (1) GB2204036B (it)
IL (1) IL85154A (it)
IT (1) IT1215751B (it)
NL (1) NL8800134A (it)
SE (1) SE467874B (it)
ZA (1) ZA88408B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341262C (en) * 1987-08-06 2001-06-26 Camille A. Boulet A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5037977A (en) * 1988-08-11 1991-08-06 Mitsui Petrochemical Industries Ltd. Method for production of dimeric alkaloids
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
HU209687B (en) * 1989-03-04 1994-10-28 Mitsui Petrochemical Ind Process for producing bisz-indole-alkaloids
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation
CN103936769B (zh) * 2014-04-30 2016-10-05 淮海工学院 一种制备高光学纯脱水长春碱的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (it) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
GB1551054A (en) * 1976-03-04 1979-08-22 Atta Ur Rahman Syntheses of vinblastine vincristine and vinrosidine
FR2358412A1 (fr) * 1976-07-13 1978-02-10 Parcor Procede de preparation de la vincamine et d'alcaloides apparentes

Also Published As

Publication number Publication date
NL8800134A (nl) 1988-08-16
FR2611202A1 (fr) 1988-08-26
SE8800170L (sv) 1988-07-23
JPH01131187A (ja) 1989-05-24
FR2611202B1 (it) 1994-08-19
CA1341261C (en) 2001-06-26
IT8819156A0 (it) 1988-01-21
GB8801296D0 (en) 1988-02-17
IL85154A (en) 1992-08-18
DE3801450A1 (de) 1988-08-18
SE467874B (sv) 1992-09-28
CH675724A5 (it) 1990-10-31
IL85154A0 (en) 1988-06-30
GB2204036B (en) 1991-03-27
JPH0613531B2 (ja) 1994-02-23
GB2204036A (en) 1988-11-02
DE3801450C2 (de) 1999-02-25
ZA88408B (en) 1989-04-26
SE8800170D0 (sv) 1988-01-20

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Effective date: 19970131