SE8800170L - Framstellning av vinblastin och vinkristin - Google Patents

Framstellning av vinblastin och vinkristin

Info

Publication number
SE8800170L
SE8800170L SE8800170A SE8800170A SE8800170L SE 8800170 L SE8800170 L SE 8800170L SE 8800170 A SE8800170 A SE 8800170A SE 8800170 A SE8800170 A SE 8800170A SE 8800170 L SE8800170 L SE 8800170L
Authority
SE
Sweden
Prior art keywords
wine
iminium intermediate
vincristine
vinblastine
blast
Prior art date
Application number
SE8800170A
Other languages
English (en)
Other versions
SE8800170D0 (sv
SE467874B (sv
Inventor
J P Kutney
L S L Choi
J Nakano
H Tsukamoto
C A Boulet
M Mchugh
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of SE8800170D0 publication Critical patent/SE8800170D0/sv
Publication of SE8800170L publication Critical patent/SE8800170L/sv
Publication of SE467874B publication Critical patent/SE467874B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE8800170A 1987-01-22 1988-01-20 Framstaellning av vinblastin och vinkristin SE467874B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000527897A CA1341261C (en) 1987-01-22 1987-01-22 Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Publications (3)

Publication Number Publication Date
SE8800170D0 SE8800170D0 (sv) 1988-01-20
SE8800170L true SE8800170L (sv) 1988-07-23
SE467874B SE467874B (sv) 1992-09-28

Family

ID=4134803

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8800170A SE467874B (sv) 1987-01-22 1988-01-20 Framstaellning av vinblastin och vinkristin

Country Status (11)

Country Link
JP (1) JPH0613531B2 (sv)
CA (1) CA1341261C (sv)
CH (1) CH675724A5 (sv)
DE (1) DE3801450C2 (sv)
FR (1) FR2611202A1 (sv)
GB (1) GB2204036B (sv)
IL (1) IL85154A (sv)
IT (1) IT1215751B (sv)
NL (1) NL8800134A (sv)
SE (1) SE467874B (sv)
ZA (1) ZA88408B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
CA1341262C (en) * 1987-08-06 2001-06-26 Camille A. Boulet A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5037977A (en) * 1988-08-11 1991-08-06 Mitsui Petrochemical Industries Ltd. Method for production of dimeric alkaloids
HU209687B (en) * 1989-03-04 1994-10-28 Mitsui Petrochemical Ind Process for producing bisz-indole-alkaloids
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation
CN103936769B (zh) * 2014-04-30 2016-10-05 淮海工学院 一种制备高光学纯脱水长春碱的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (sv) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
GB1551054A (en) * 1976-03-04 1979-08-22 Atta Ur Rahman Syntheses of vinblastine vincristine and vinrosidine
FR2358412A1 (fr) * 1976-07-13 1978-02-10 Parcor Procede de preparation de la vincamine et d'alcaloides apparentes

Also Published As

Publication number Publication date
JPH0613531B2 (ja) 1994-02-23
IT1215751B (it) 1990-02-22
NL8800134A (nl) 1988-08-16
DE3801450A1 (de) 1988-08-18
IT8819156A0 (it) 1988-01-21
JPH01131187A (ja) 1989-05-24
SE8800170D0 (sv) 1988-01-20
GB8801296D0 (en) 1988-02-17
SE467874B (sv) 1992-09-28
GB2204036B (en) 1991-03-27
CA1341261C (en) 2001-06-26
ZA88408B (en) 1989-04-26
IL85154A0 (en) 1988-06-30
IL85154A (en) 1992-08-18
FR2611202B1 (sv) 1994-08-19
FR2611202A1 (fr) 1988-08-26
DE3801450C2 (de) 1999-02-25
CH675724A5 (sv) 1990-10-31
GB2204036A (en) 1988-11-02

Similar Documents

Publication Publication Date Title
Dolphin Porphyrinogens and porphodimethenes, intermediates in the synthesis of meso‐tetraphenylporphins from pyrroles and benzaldehyde
Govindachari et al. Alkaloids of Mappia foetida
US4144237A (en) Synthetic vinblastine and vincristine derivatives
Ban et al. Novel photoisomerization of 1-acylindoles to 3-acylindolenines. General entry to the total synthesis of Strychnos and Aspidosperma alkaloids
Cosulich et al. Crystal and molecular structure of LL-S88. alpha., an antiviral epidithiapiperazinedione derivative from Aspergillus terreus
SE8800170D0 (sv) Framstellning av vinblastin och vinkristin
DE3376323D1 (en) Process for producing beta-carboline derivatives
ES8503685A1 (es) Un procedimiento para preparar derivados de pirazolo (3,4-b) piridina
Marcelis et al. Inverse electron demand diels-alder reactions of 5-nitropyrimidine with enamines. synthesis of 3-nitropyridine derivatives
Van Tamelen et al. The biogenetic-type total synthesis of ajmaline
IL76353A0 (en) Preparation of 4-phenylpyrrole derivatives
Polz et al. Biotransformation of ajmaline in plant cell cultures of rauwolfia serpentina benth.: The new indole alkaloids raumacline and N (b)-methylraumacline.
KURIHARA et al. Reactions of ethyl 3-ethoxymethylene-2, 4-dioxovalerate and ethyl ethoxymethyleneoxaloacetate with indole analogs
Güller et al. Synthesis of aristotelia-type alkaloids. Part X. Biomimetic transformation of synthetic (+)-aristoteline into (−)-alloaristoteline.
Kozyrev et al. LiOH promoted allomerization of pyropheophorbide a. A convenient synthesis of 13 2-oxopyropheophorbide a and its unusual enolization
Badger et al. 842. Porphyrins. Part I. Intramolecular hydrogen bonding in pyrromethenes and porphyrins
SE8802813L (sv) Saett att framstaella vinblastin och vinkristin
Coppola Novel heterocycles. I. Synthesis and reactions of 6, 7‐dihydro‐1H, 3H, 5H‐pyrido [3, 2, l‐ij][3, 1] benzoxazine‐1, 3‐dione
IE870199L (en) Heterocyclic compounds and their production.
EP0354778A3 (en) Method for production of dimeric alkaloids
GB1459908A (en) Process for the preparation of tropane alkaloids
GB1514337A (en) Process for the preparation of vincamine and other indole alkaloids
Ahmad et al. Cohirsine-A novel Isoquinolone alkaloid from Cocculus hirsutus
Bonjoch et al. A stereoselective total synthesis of dasycarpidan alkaloids:(±)-dasycarpidone,(±)-dasycarpidol and (±)-nordasycarpidone
Danieli et al. A new tryptophan derived alkaloid from Evodia rutaecarpa (Juss.) Benth. et Hook

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8800170-6

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8800170-6

Format of ref document f/p: F