GB2204036B - Process for the synthesis of vinblastine and vincristine - Google Patents

Process for the synthesis of vinblastine and vincristine

Info

Publication number
GB2204036B
GB2204036B GB8801296A GB8801296A GB2204036B GB 2204036 B GB2204036 B GB 2204036B GB 8801296 A GB8801296 A GB 8801296A GB 8801296 A GB8801296 A GB 8801296A GB 2204036 B GB2204036 B GB 2204036B
Authority
GB
United Kingdom
Prior art keywords
vinblastine
vincristine
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8801296A
Other versions
GB8801296D0 (en
GB2204036A (en
Inventor
James P Kutney
Lewis S L Choi
Jun Nakano
Hiroki Tsukamoto
Camille A Boulet
Michael Mchugh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of GB8801296D0 publication Critical patent/GB8801296D0/en
Publication of GB2204036A publication Critical patent/GB2204036A/en
Application granted granted Critical
Publication of GB2204036B publication Critical patent/GB2204036B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
GB8801296A 1987-01-22 1988-01-21 Process for the synthesis of vinblastine and vincristine Expired - Lifetime GB2204036B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000527897A CA1341261C (en) 1987-01-22 1987-01-22 Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Publications (3)

Publication Number Publication Date
GB8801296D0 GB8801296D0 (en) 1988-02-17
GB2204036A GB2204036A (en) 1988-11-02
GB2204036B true GB2204036B (en) 1991-03-27

Family

ID=4134803

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8801296A Expired - Lifetime GB2204036B (en) 1987-01-22 1988-01-21 Process for the synthesis of vinblastine and vincristine

Country Status (11)

Country Link
JP (1) JPH0613531B2 (en)
CA (1) CA1341261C (en)
CH (1) CH675724A5 (en)
DE (1) DE3801450C2 (en)
FR (1) FR2611202A1 (en)
GB (1) GB2204036B (en)
IL (1) IL85154A (en)
IT (1) IT1215751B (en)
NL (1) NL8800134A (en)
SE (1) SE467874B (en)
ZA (1) ZA88408B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341262C (en) * 1987-08-06 2001-06-26 Camille A. Boulet A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5037977A (en) * 1988-08-11 1991-08-06 Mitsui Petrochemical Industries Ltd. Method for production of dimeric alkaloids
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
HU209687B (en) * 1989-03-04 1994-10-28 Mitsui Petrochemical Ind Process for producing bisz-indole-alkaloids
FR2779146B1 (en) * 1998-06-02 2002-01-18 Roowin NOVEL VINCA-ALKALOIDE DERIVATIVES AND PREPARATION METHODS
CN103936769B (en) * 2014-04-30 2016-10-05 淮海工学院 A kind of method preparing high optical voidness F 81097

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (en) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
GB1551054A (en) * 1976-03-04 1979-08-22 Atta Ur Rahman Syntheses of vinblastine vincristine and vinrosidine
FR2358412A1 (en) * 1976-07-13 1978-02-10 Parcor PROCESS FOR THE PREPARATION OF VINCAMINE AND RELATED ALKALOIDS

Also Published As

Publication number Publication date
NL8800134A (en) 1988-08-16
FR2611202A1 (en) 1988-08-26
SE8800170L (en) 1988-07-23
JPH01131187A (en) 1989-05-24
FR2611202B1 (en) 1994-08-19
CA1341261C (en) 2001-06-26
IT8819156A0 (en) 1988-01-21
GB8801296D0 (en) 1988-02-17
IL85154A (en) 1992-08-18
DE3801450A1 (en) 1988-08-18
SE467874B (en) 1992-09-28
CH675724A5 (en) 1990-10-31
IT1215751B (en) 1990-02-22
IL85154A0 (en) 1988-06-30
JPH0613531B2 (en) 1994-02-23
GB2204036A (en) 1988-11-02
DE3801450C2 (en) 1999-02-25
ZA88408B (en) 1989-04-26
SE8800170D0 (en) 1988-01-20

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20000121