CH674363A5 - - Google Patents

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Publication number
CH674363A5
CH674363A5 CH4345/87A CH434587A CH674363A5 CH 674363 A5 CH674363 A5 CH 674363A5 CH 4345/87 A CH4345/87 A CH 4345/87A CH 434587 A CH434587 A CH 434587A CH 674363 A5 CH674363 A5 CH 674363A5
Authority
CH
Switzerland
Prior art keywords
formula
compounds
compound
compounds according
salts
Prior art date
Application number
CH4345/87A
Other languages
German (de)
English (en)
Inventor
George William Holland
Hans Maag
Perry Rosen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH674363A5 publication Critical patent/CH674363A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
CH4345/87A 1986-12-01 1987-11-06 CH674363A5 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93652286A 1986-12-01 1986-12-01

Publications (1)

Publication Number Publication Date
CH674363A5 true CH674363A5 (ko) 1990-05-31

Family

ID=25468757

Family Applications (1)

Application Number Title Priority Date Filing Date
CH4345/87A CH674363A5 (ko) 1986-12-01 1987-11-06

Country Status (14)

Country Link
JP (1) JPS63145275A (ko)
AT (1) AT391697B (ko)
AU (1) AU597128B2 (ko)
BE (1) BE1001271A5 (ko)
CH (1) CH674363A5 (ko)
DE (1) DE3740595A1 (ko)
DK (1) DK627787A (ko)
FR (1) FR2607501A1 (ko)
GB (1) GB2198130B (ko)
IT (1) IT1223390B (ko)
NL (1) NL8702855A (ko)
NZ (1) NZ222723A (ko)
SE (1) SE8704770L (ko)
ZA (1) ZA878947B (ko)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2088856B (en) * 1980-10-27 1984-06-27 Chinoin Gyogyszer Es Vegyeszet 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
EP0054795B1 (en) * 1980-12-09 1987-07-15 Teijin Limited Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
US4558142A (en) * 1981-03-11 1985-12-10 Hoffmann-La Roche Inc. 7-Fluoro-prostacyclin analogs
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
JPS5867682A (ja) * 1981-10-16 1983-04-22 Teijin Ltd フルオロpgi↓2類の製法
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd 7−フルオロプロスタグランジン類の製造方法
US4634782A (en) * 1985-06-24 1987-01-06 Hoffmann-La Roche Inc. 7-fluoro-dihydro PGI compounds

Also Published As

Publication number Publication date
AU597128B2 (en) 1990-05-24
SE8704770L (sv) 1988-06-02
IT1223390B (it) 1990-09-19
GB2198130B (en) 1990-08-08
BE1001271A5 (fr) 1989-09-12
NZ222723A (en) 1990-11-27
GB8727991D0 (en) 1988-01-06
AU8190787A (en) 1988-06-02
FR2607501A1 (fr) 1988-06-03
JPS63145275A (ja) 1988-06-17
ATA313887A (de) 1990-05-15
IT8722814A0 (it) 1987-11-30
DK627787D0 (da) 1987-11-30
DK627787A (da) 1988-06-02
NL8702855A (nl) 1988-07-01
DE3740595A1 (de) 1988-06-16
AT391697B (de) 1990-11-12
SE8704770D0 (sv) 1987-11-30
GB2198130A (en) 1988-06-08
ZA878947B (en) 1988-06-01

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PL Patent ceased