CH655719A5 - Derives de piperazine ou leurs sels, procede de production et ces derives et un medicament ameliorant la circulation cerebrale. - Google Patents

Derives de piperazine ou leurs sels, procede de production et ces derives et un medicament ameliorant la circulation cerebrale. Download PDF

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Publication number
CH655719A5
CH655719A5 CH3953/83A CH395383A CH655719A5 CH 655719 A5 CH655719 A5 CH 655719A5 CH 3953/83 A CH3953/83 A CH 3953/83A CH 395383 A CH395383 A CH 395383A CH 655719 A5 CH655719 A5 CH 655719A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
group containing
lower alkoxy
group
hydrogen atom
Prior art date
Application number
CH3953/83A
Other languages
English (en)
French (fr)
Inventor
Mitsuo Masaki
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of CH655719A5 publication Critical patent/CH655719A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH3953/83A 1982-12-02 1983-07-19 Derives de piperazine ou leurs sels, procede de production et ces derives et un medicament ameliorant la circulation cerebrale. CH655719A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57212036A JPS59101475A (ja) 1982-12-02 1982-12-02 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤

Publications (1)

Publication Number Publication Date
CH655719A5 true CH655719A5 (fr) 1986-05-15

Family

ID=16615802

Family Applications (1)

Application Number Title Priority Date Filing Date
CH3953/83A CH655719A5 (fr) 1982-12-02 1983-07-19 Derives de piperazine ou leurs sels, procede de production et ces derives et un medicament ameliorant la circulation cerebrale.

Country Status (11)

Country Link
US (1) US4528194A (en, 2012)
JP (1) JPS59101475A (en, 2012)
KR (1) KR900003277B1 (en, 2012)
BR (1) BR8304319A (en, 2012)
CH (1) CH655719A5 (en, 2012)
DE (1) DE3326148A1 (en, 2012)
ES (2) ES8604911A1 (en, 2012)
FR (1) FR2541275B1 (en, 2012)
GB (2) GB8318683D0 (en, 2012)
IT (1) IT1162913B (en, 2012)
SE (1) SE464707B (en, 2012)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424685A1 (de) * 1984-07-05 1986-02-06 Beiersdorf Ag, 2000 Hamburg Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPS61161272A (ja) * 1985-01-11 1986-07-21 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
JPH08776B2 (ja) * 1986-08-20 1996-01-10 日本ケミフア株式会社 脳細胞保護作用を有する医薬組成物
US4978666A (en) * 1988-08-05 1990-12-18 Nippon Chemiphar Co., Ltd. Optically active piperazine derivative
JP2679872B2 (ja) * 1989-04-28 1997-11-19 明治製菓株式会社 Ｎ−置換ピペラジン誘導体を含む脳機能障害改善剤
WO1990013539A1 (en) * 1989-04-28 1990-11-15 Meiji Seika Kaisha, Ltd. New n-substituted piperazine derivatives and drug for improving functional disorder of brain
DE4108527A1 (de) * 1991-03-15 1992-09-17 Basf Ag Neue 1-(4-cyano-4-aryl-cyclohexyl)piperazine, ihre herstellung und verwendung
DE4404249C2 (de) * 1994-02-10 2001-10-18 Basf Ag Substituierte Cycloalkyl-piperazinyl-ethanol, ihre Herstellung und diese enthaltende Arzneimittel
KR100472086B1 (ko) * 2001-11-23 2005-02-21 한국화학연구원 항산화 활성을 갖는 3,5-디알콕시-4-히드록시페닐기로치환된 피페라진 유도체, 그의 제조방법 및 이를 포함하는약학적 조성물
US8186436B2 (en) * 2009-09-10 2012-05-29 Warren Carlos Thermal insulating packer fluid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131192C (en, 2012) * 1965-06-16
FR2081579B1 (en, 2012) * 1970-03-18 1973-04-06 Delalande Sa
FR2163358A1 (en) * 1971-12-15 1973-07-27 Synthelabo Phenylalkanolamine derivs - with effects on the smooth musculature
NL7306771A (en, 2012) * 1972-06-02 1973-12-04
JPS504087A (en, 2012) * 1973-05-17 1975-01-16

Also Published As

Publication number Publication date
DE3326148C2 (en, 2012) 1989-11-16
JPH0254832B2 (en, 2012) 1990-11-22
KR900003277B1 (ko) 1990-05-12
GB2131016B (en) 1985-11-20
IT1162913B (it) 1987-04-01
IT8367776A0 (it) 1983-07-19
JPS59101475A (ja) 1984-06-12
ES8603449A1 (es) 1986-01-01
DE3326148A1 (de) 1984-06-07
ES543397A0 (es) 1986-01-01
SE8304071L (sv) 1984-06-03
GB8318683D0 (en) 1983-08-10
GB8319317D0 (en) 1983-08-17
US4528194A (en) 1985-07-09
ES8604911A1 (es) 1986-03-16
SE8304071D0 (sv) 1983-07-20
BR8304319A (pt) 1984-11-06
KR840006983A (ko) 1984-12-04
GB2131016A (en) 1984-06-13
ES524283A0 (es) 1986-03-16
FR2541275B1 (fr) 1986-02-07
FR2541275A1 (fr) 1984-08-24
SE464707B (sv) 1991-06-03

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PL Patent ceased