CH644113A5 - N-substituted 2,6-dimethylmorpholine compounds - Google Patents

N-substituted 2,6-dimethylmorpholine compounds Download PDF

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Publication number
CH644113A5
CH644113A5 CH756079A CH756079A CH644113A5 CH 644113 A5 CH644113 A5 CH 644113A5 CH 756079 A CH756079 A CH 756079A CH 756079 A CH756079 A CH 756079A CH 644113 A5 CH644113 A5 CH 644113A5
Authority
CH
Switzerland
Prior art keywords
formula
compounds
acid
salts
preparation
Prior art date
Application number
CH756079A
Other languages
German (de)
English (en)
Inventor
Albert Dr Pfiffner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH756079A priority Critical patent/CH644113A5/de
Priority to ZW157/80A priority patent/ZW15780A1/xx
Priority to IT23283/80A priority patent/IT1220970B/it
Priority to YU1754/80A priority patent/YU43475B/xx
Priority to SI8011754A priority patent/SI8011754A8/sl
Priority to CA356,038A priority patent/CA1128943A/en
Priority to AR281915A priority patent/AR225318A1/es
Priority to BR8004705A priority patent/BR8004705A/pt
Priority to CS816797A priority patent/CS227329B2/cs
Priority to CS805307A priority patent/CS227310B2/cs
Priority to CU8035298A priority patent/CU35298A/es
Priority to FI802418A priority patent/FI69455C/fi
Priority to PH24406A priority patent/PH15480A/en
Priority to EP80104656A priority patent/EP0024334B1/de
Priority to DE19803029966 priority patent/DE3029966A1/de
Priority to AT80104656T priority patent/ATE4206T1/de
Priority to DE8080104656T priority patent/DE3064267D1/de
Priority to DE1993175077 priority patent/DE19375077I2/de
Priority to NL8004537A priority patent/NL8004537A/nl
Priority to IL60813A priority patent/IL60813A/xx
Priority to NZ194628A priority patent/NZ194628A/en
Priority to AU61321/80A priority patent/AU530398B2/en
Priority to ZA00804866A priority patent/ZA804866B/xx
Priority to GR62680A priority patent/GR69944B/el
Priority to MC801466A priority patent/MC1345A1/xx
Priority to LU82713A priority patent/LU82713A1/de
Priority to FR8017977A priority patent/FR2463767B1/fr
Priority to PT71708A priority patent/PT71708B/pt
Priority to NO802453A priority patent/NO153176C/no
Priority to GB8026709A priority patent/GB2056454B/en
Priority to DK355180A priority patent/DK150509C/da
Priority to JP11185280A priority patent/JPS5677269A/ja
Priority to SE8005784A priority patent/SE447730B/sv
Priority to HU802034A priority patent/HU182189B/hu
Priority to IE1729/80A priority patent/IE52642B1/en
Priority to KR1019800003239A priority patent/KR840001472B1/ko
Priority to ES494314A priority patent/ES494314A0/es
Priority to ES499956A priority patent/ES499956A0/es
Priority to ES499957A priority patent/ES499957A0/es
Priority to ES499955A priority patent/ES499955A0/es
Priority to CS816796A priority patent/CS227328B2/cs
Publication of CH644113A5 publication Critical patent/CH644113A5/de
Priority to MY272/85A priority patent/MY8500272A/xx
Priority to CS914020A priority patent/CS402091A3/cs
Priority to MX9203269A priority patent/MX9203269A/es
Priority to HRP-1754/80A priority patent/HRP930340B1/xx
Priority to BG98580A priority patent/BG60798B2/bg
Priority to NO1994009C priority patent/NO1994009I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH756079A 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds CH644113A5 (en)

Priority Applications (47)

Application Number Priority Date Filing Date Title
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds
ZW157/80A ZW15780A1 (en) 1979-08-17 1980-07-07 Heterocyclic compounds
IT23283/80A IT1220970B (it) 1979-08-17 1980-07-07 Composti eteterociclici ad azione fungicida particolare per la lotta contro la candida albicans
YU1754/80A YU43475B (en) 1979-08-17 1980-07-08 Process for producing morpholine derivatives
SI8011754A SI8011754A8 (sl) 1979-08-17 1980-07-08 Postopek za proizvodnjo derivatov morfolina
CA356,038A CA1128943A (en) 1979-08-17 1980-07-11 Morpholine derivatives
AR281915A AR225318A1 (es) 1979-08-17 1980-07-25 Procedimiento para preparar fenil-propil-morfolinas sustituidas
BR8004705A BR8004705A (pt) 1979-08-17 1980-07-28 Compostos heterociclicos, processo para manufactura de tais compostos, preparacao farmaceutica e uso dos compostos
CS816797A CS227329B2 (cs) 1979-08-17 1980-07-29 Způsob výroby derivátů morfolinu
CS805307A CS227310B2 (en) 1979-08-17 1980-07-29 Method of preparing morpholine derivatives
CU8035298A CU35298A (en) 1979-08-17 1980-07-30 Heterocyclic compounds
FI802418A FI69455C (fi) 1979-08-17 1980-08-01 Foerfarande foer framstaellning av cis-2,6-dimetylmorfolinderivat med fungicid verkan
PH24406A PH15480A (en) 1979-08-17 1980-08-05 Heterocyclic compounds
EP80104656A EP0024334B1 (de) 1979-08-17 1980-08-07 Neue Morpholinderivate, Verfahren zu deren Herstellung, diese Derivate enthaltende pharmazeutische Präparate
DE19803029966 DE3029966A1 (de) 1979-08-17 1980-08-07 Heterocyclische verbindungen
AT80104656T ATE4206T1 (de) 1979-08-17 1980-08-07 Neue morpholinderivate, verfahren zu deren herstellung, diese derivate enthaltende pharmazeutische praeparate.
DE8080104656T DE3064267D1 (en) 1979-08-17 1980-08-07 Morpholine derivatives, process for their production, pharmaceutical preparations containing these derivatives
DE1993175077 DE19375077I2 (de) 1979-08-17 1980-08-07 Neue Morpholinderivate Verfahren zu deren Herstellung diese Derivate enthaltende pharmazeutische Praeparate
NL8004537A NL8004537A (nl) 1979-08-17 1980-08-08 Heterocyclische verbindingen.
IL60813A IL60813A (en) 1979-08-17 1980-08-11 Cis-4-(3-p-(tert-amyl-phenyl and alpha,alpha-dimethyl-benzyl-phenyl)-2-methylpropyl)-2,6-dimethyl-morpholines,their preparation and pharmaceutical compositions containing them
NZ194628A NZ194628A (en) 1979-08-17 1980-08-11 Cis-4-(3-p-(tert-amyl or alpha,alpha-dimethylbenzyl)phenyl-2-methylpropyl)-2,6-dimethylmorpholines
AU61321/80A AU530398B2 (en) 1979-08-17 1980-08-11 N-substituted-2,6-dimethylmorpholine derivatives
ZA00804866A ZA804866B (en) 1979-08-17 1980-08-11 Heterocyclic compounds
GR62680A GR69944B (ru) 1979-08-17 1980-08-14
MC801466A MC1345A1 (fr) 1979-08-17 1980-08-14 Procede pour la preparation de composes heterocycliques
LU82713A LU82713A1 (de) 1979-08-17 1980-08-14 Heterocyclische verbindungen
FR8017977A FR2463767B1 (fr) 1979-08-17 1980-08-14 Nouveaux derives de cis-4-(3-phenyl-2-methyl-propyl)-2,6-dimethyl-morpholine, leur procede de preparation et medicaments les contenant
PT71708A PT71708B (en) 1979-08-17 1980-08-14 Process for preparing phenyl-propyl-morpholinic substituted compounds
NO802453A NO153176C (no) 1979-08-17 1980-08-15 Analogifremgangsmaate ved fremstilling av den terapeutisk virksomme cis-isomer av morfolinderivater.
GB8026709A GB2056454B (en) 1979-08-17 1980-08-15 2,6 - dimethyl morpholine derivatives
DK355180A DK150509C (da) 1979-08-17 1980-08-15 Analogifremgangsmaade til fremstilling af cis-4-(3-phenyl-2-methyl-propyl)-2,6-dimethylmorpholiner
JP11185280A JPS5677269A (en) 1979-08-17 1980-08-15 Heterocyclic compound
SE8005784A SE447730B (sv) 1979-08-17 1980-08-15 Morfolinderivat, forfarande for framstellning derav samt farmaceutiska preparat innehallande sadana foreningar till anvendning som antimykotika
HU802034A HU182189B (en) 1979-08-17 1980-08-15 Process for preparing morpholine compounds
IE1729/80A IE52642B1 (en) 1979-08-17 1980-08-15 Morpholine derivatives,process for preparing them and use of said morpholine derivatives in pharmaceutical preparations
ES494314A ES494314A0 (es) 1979-08-17 1980-08-16 Un procedimiento para la preparacion de compuestos heteroci-clicos
KR1019800003239A KR840001472B1 (ko) 1979-08-17 1980-08-16 모르폴린 유도체의 제조방법
ES499956A ES499956A0 (es) 1979-08-17 1981-03-02 Un procedimiento para la preparacion de compuestos heteroci-clicos
ES499957A ES499957A0 (es) 1979-08-17 1981-03-02 Un procedimiento para la preparacion de compuestos heteroci-clicos
ES499955A ES499955A0 (es) 1979-08-17 1981-03-02 Un procedimiento para la preparacion de compuestos heteroci-clicos
CS816796A CS227328B2 (cs) 1979-08-17 1981-09-15 Způsob výroby derivátů morfolinu
MY272/85A MY8500272A (en) 1979-08-17 1985-12-30 Substituted-phenyl propyl morpholines
CS914020A CS402091A3 (en) 1979-08-17 1991-12-23 Morpholine derivatives and pharmaceuticals based thereon
MX9203269A MX9203269A (es) 1979-08-17 1992-06-24 Compuestos heterociclicos y composiciones farmaceuticas que los contienen.
HRP-1754/80A HRP930340B1 (en) 1979-08-17 1993-03-12 Process for the preparation of morpholine derivatives
BG98580A BG60798B2 (bg) 1979-08-17 1994-02-25 Нови морфолинови производни,метод за тяхното получаване, фармацевтични средства,съдържащи тези производни,и използването им като антимикотици
NO1994009C NO1994009I1 (no) 1979-08-17 1994-08-03 Amorolfin/ cis-4-(3-(4-(1,1-dimetylpropyl)-fenyl)-2-metylpropyl-2,6-dimetylmorfolin.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds

Publications (1)

Publication Number Publication Date
CH644113A5 true CH644113A5 (en) 1984-07-13

Family

ID=4327075

Family Applications (1)

Application Number Title Priority Date Filing Date
CH756079A CH644113A5 (en) 1979-08-17 1979-08-17 N-substituted 2,6-dimethylmorpholine compounds

Country Status (10)

Country Link
JP (1) JPS5677269A (ru)
KR (1) KR840001472B1 (ru)
BR (1) BR8004705A (ru)
CH (1) CH644113A5 (ru)
CS (3) CS227310B2 (ru)
ES (2) ES499956A0 (ru)
GR (1) GR69944B (ru)
MX (1) MX9203269A (ru)
NO (1) NO1994009I1 (ru)
ZA (1) ZA804866B (ru)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354187B (de) * 1976-11-22 1979-12-27 Hoffmann La Roche Fungizides mittel
DE2656747C2 (de) * 1976-12-15 1984-07-05 Basf Ag, 6700 Ludwigshafen Morpholinderivate
JPS6236516A (ja) * 1985-08-12 1987-02-17 Matsushita Electric Ind Co Ltd 角速度センサ

Also Published As

Publication number Publication date
MX9203269A (es) 1992-07-01
JPH0248553B2 (ru) 1990-10-25
CS227310B2 (en) 1984-04-16
BR8004705A (pt) 1981-04-28
CS227329B2 (cs) 1984-04-16
ES8201561A1 (es) 1982-01-01
JPS5677269A (en) 1981-06-25
ES8201562A1 (es) 1982-01-01
NO1994009I1 (no) 1994-08-03
CS227328B2 (cs) 1984-04-16
ZA804866B (en) 1981-08-26
KR840001472B1 (ko) 1984-09-28
ES499956A0 (es) 1982-01-01
GR69944B (ru) 1982-07-21
KR830003448A (ko) 1983-06-20
ES499955A0 (es) 1982-01-01

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PL Patent ceased