CH642259A5 - Galenische zubereitungen fuer orale applikation von ergotalkaloiden. - Google Patents
Galenische zubereitungen fuer orale applikation von ergotalkaloiden. Download PDFInfo
- Publication number
- CH642259A5 CH642259A5 CH626380A CH626380A CH642259A5 CH 642259 A5 CH642259 A5 CH 642259A5 CH 626380 A CH626380 A CH 626380A CH 626380 A CH626380 A CH 626380A CH 642259 A5 CH642259 A5 CH 642259A5
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation according
- core
- coating
- cores
- sterol ether
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1301978 | 1978-12-21 | ||
| CH1302178 | 1978-12-21 | ||
| CH56679 | 1979-01-19 | ||
| CH56779 | 1979-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH642259A5 true CH642259A5 (de) | 1984-04-13 |
Family
ID=27427929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH626380A CH642259A5 (de) | 1978-12-21 | 1979-12-12 | Galenische zubereitungen fuer orale applikation von ergotalkaloiden. |
Country Status (23)
| Country | Link |
|---|---|
| AT (1) | AT372279B (fr) |
| AU (1) | AU534051B2 (fr) |
| CA (1) | CA1139222A (fr) |
| CH (1) | CH642259A5 (fr) |
| CY (1) | CY1330A (fr) |
| DE (1) | DE2950154A1 (fr) |
| DK (1) | DK154607C (fr) |
| FI (1) | FI793888A (fr) |
| FR (1) | FR2444463A1 (fr) |
| GB (1) | GB2038181B (fr) |
| HK (1) | HK37986A (fr) |
| HU (1) | HU182577B (fr) |
| IE (1) | IE49323B1 (fr) |
| IL (1) | IL59003A (fr) |
| IT (1) | IT1164029B (fr) |
| KE (1) | KE3617D (fr) |
| MY (1) | MY8500129A (fr) |
| NL (1) | NL187229C (fr) |
| NZ (1) | NZ192457A (fr) |
| PH (1) | PH25178A (fr) |
| PT (1) | PT70614A (fr) |
| SE (1) | SE442265B (fr) |
| WO (1) | WO1980001242A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3264867D1 (en) * | 1981-04-27 | 1985-08-29 | Haessle Ab | New pharmaceutical preparation |
| US4366145A (en) * | 1981-06-24 | 1982-12-28 | Sandoz, Inc. | Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation |
| HU192050B (en) * | 1983-04-22 | 1987-05-28 | Sandoz Ag | Process for production of medical preparative containing co-dergocrin and one piridin-dicarbonic acid diesthertype calcium-antagonist |
| DE3413955A1 (de) * | 1983-04-22 | 1984-10-25 | Sandoz-Patent-GmbH, 7850 Lörrach | Pharmazeutisches praeparat enthaltend co-dergocrine und einen calcium-antagonisten |
| NL194389C (nl) * | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
| GB8426922D0 (en) * | 1984-10-24 | 1984-11-28 | Sandoz Ltd | Galenic formulation |
| AT388101B (de) * | 1985-02-05 | 1989-05-10 | Sandoz Ag | Verfahren zur herstellung einer pharmazeutischen zusammensetzung zur oralen verabreichung mit kontrollierter wirkstofffreisetzung |
| CN1003978B (zh) * | 1987-09-05 | 1989-04-26 | 广州陈李济药厂 | 一种补脾益肠丸的制备工艺 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3432593A (en) * | 1963-09-18 | 1969-03-11 | Key Pharm Inc | Delayed and sustained release type pharmaceutical preparation |
| DE2528257C2 (de) * | 1974-07-04 | 1986-02-13 | Sandoz-Patent-GmbH, 7850 Lörrach | Neue galenische Zubereitung |
| DE2546577B2 (de) * | 1975-10-17 | 1981-04-02 | Sandoz-Patent-GmbH, 7850 Lörrach | Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden |
-
1979
- 1979-12-12 WO PCT/CH1979/000160 patent/WO1980001242A1/fr unknown
- 1979-12-12 DK DK529879A patent/DK154607C/da not_active IP Right Cessation
- 1979-12-12 FI FI793888A patent/FI793888A/fi not_active Application Discontinuation
- 1979-12-12 CH CH626380A patent/CH642259A5/de not_active IP Right Cessation
- 1979-12-12 SE SE7910227A patent/SE442265B/sv not_active IP Right Cessation
- 1979-12-13 DE DE19792950154 patent/DE2950154A1/de active Granted
- 1979-12-18 NL NLAANVRAGE7909105,A patent/NL187229C/xx not_active IP Right Cessation
- 1979-12-19 IL IL59003A patent/IL59003A/xx unknown
- 1979-12-19 PH PH23436A patent/PH25178A/en unknown
- 1979-12-19 IE IE2471/79A patent/IE49323B1/en unknown
- 1979-12-19 NZ NZ192457A patent/NZ192457A/xx unknown
- 1979-12-19 GB GB7943633A patent/GB2038181B/en not_active Expired
- 1979-12-19 PT PT70614A patent/PT70614A/fr not_active IP Right Cessation
- 1979-12-19 CY CY1330A patent/CY1330A/xx unknown
- 1979-12-19 AU AU54031/79A patent/AU534051B2/en not_active Ceased
- 1979-12-19 CA CA000342212A patent/CA1139222A/fr not_active Expired
- 1979-12-20 HU HU79SA3216A patent/HU182577B/hu not_active IP Right Cessation
- 1979-12-20 FR FR7931229A patent/FR2444463A1/fr active Granted
- 1979-12-20 AT AT0803679A patent/AT372279B/de active
- 1979-12-20 IT IT51153/79A patent/IT1164029B/it active
-
1985
- 1985-12-30 MY MY129/85A patent/MY8500129A/xx unknown
-
1986
- 1986-03-18 KE KE3617BD patent/KE3617D/xx unknown
- 1986-05-22 HK HK379/86A patent/HK37986A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY8500129A (en) | 1985-12-31 |
| DK529879A (da) | 1980-06-22 |
| IL59003A (en) | 1982-12-31 |
| NL7909105A (nl) | 1980-06-24 |
| GB2038181A (en) | 1980-07-23 |
| IE49323B1 (en) | 1985-09-18 |
| NL187229C (nl) | 1991-07-16 |
| SE442265B (sv) | 1985-12-16 |
| IT7951153A0 (it) | 1979-12-20 |
| CY1330A (en) | 1986-06-27 |
| GB2038181B (en) | 1983-05-11 |
| AU534051B2 (en) | 1984-01-05 |
| WO1980001242A1 (fr) | 1980-06-26 |
| PT70614A (fr) | 1980-01-01 |
| AT372279B (de) | 1983-09-26 |
| FR2444463A1 (fr) | 1980-07-18 |
| DE2950154C2 (fr) | 1989-05-11 |
| FR2444463B1 (fr) | 1983-02-25 |
| NZ192457A (en) | 1983-06-17 |
| IE792471L (en) | 1980-06-21 |
| CA1139222A (fr) | 1983-01-11 |
| AU5403179A (en) | 1980-06-26 |
| DK154607C (da) | 1989-06-05 |
| SE7910227L (sv) | 1980-06-22 |
| DE2950154A1 (de) | 1980-07-10 |
| HK37986A (en) | 1986-05-30 |
| HU182577B (en) | 1984-02-28 |
| DK154607B (da) | 1988-12-05 |
| IT1164029B (it) | 1987-04-08 |
| KE3617D (en) | 1986-04-18 |
| ATA803679A (de) | 1983-02-15 |
| PH25178A (en) | 1991-03-27 |
| FI793888A (fi) | 1980-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SPCF | Supplementary protection certificate filed |
Free format text: IKS 46123/850619 |
|
| SPCF | Supplementary protection certificate filed |
Free format text: IKS 46123/850619, 951214 |
|
| SPCW | Supplementary protection certificate withdrawn |
Free format text: IKS 46123/19850619, 19951214 |
|
| PFA | Name/firm changed |
Owner name: SANDOZ AG TRANSFER- NOVARTIS AG |
|
| PL | Patent ceased |