CH630098A5 - Process for the preparation of derivatives of 9-chloroprednisolone - Google Patents
Process for the preparation of derivatives of 9-chloroprednisolone Download PDFInfo
- Publication number
- CH630098A5 CH630098A5 CH1199177A CH1199177A CH630098A5 CH 630098 A5 CH630098 A5 CH 630098A5 CH 1199177 A CH1199177 A CH 1199177A CH 1199177 A CH1199177 A CH 1199177A CH 630098 A5 CH630098 A5 CH 630098A5
- Authority
- CH
- Switzerland
- Prior art keywords
- dione
- hydroxy
- chloro
- pregnadiene
- butyryloxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2645105A DE2645105C2 (de) | 1976-10-04 | 1976-10-04 | Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat |
| DE19772742982 DE2742982C2 (de) | 1977-09-21 | 1977-09-21 | 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH630098A5 true CH630098A5 (en) | 1982-05-28 |
Family
ID=25770978
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1199177A CH630098A5 (en) | 1976-10-04 | 1977-09-30 | Process for the preparation of derivatives of 9-chloroprednisolone |
| CH579381A CH632278A5 (en) | 1976-10-04 | 1981-09-08 | Process for the preparation of novel derivatives of 9-chloroprednisolone |
| CH579281A CH632772A5 (en) | 1976-10-04 | 1981-09-08 | Process for preparing novel derivatives of 9-chloroprednisolone |
| CH579481A CH631997A5 (en) | 1976-10-04 | 1981-09-08 | Process for the preparation of novel derivatives of 9-chloro-prednisolone |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH579381A CH632278A5 (en) | 1976-10-04 | 1981-09-08 | Process for the preparation of novel derivatives of 9-chloroprednisolone |
| CH579281A CH632772A5 (en) | 1976-10-04 | 1981-09-08 | Process for preparing novel derivatives of 9-chloroprednisolone |
| CH579481A CH631997A5 (en) | 1976-10-04 | 1981-09-08 | Process for the preparation of novel derivatives of 9-chloro-prednisolone |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5359654A (pt) |
| AT (1) | AT358202B (pt) |
| CH (4) | CH630098A5 (pt) |
| DK (1) | DK438277A (pt) |
| ES (1) | ES462887A1 (pt) |
| FI (1) | FI58645C (pt) |
| FR (1) | FR2366313A1 (pt) |
| GB (1) | GB1594852A (pt) |
| GR (1) | GR73041B (pt) |
| HU (1) | HU179593B (pt) |
| IE (1) | IE45877B1 (pt) |
| IL (1) | IL53030A (pt) |
| IT (1) | IT1113623B (pt) |
| LU (1) | LU78223A1 (pt) |
| NL (1) | NL7710869A (pt) |
| NO (1) | NO148597C (pt) |
| NZ (1) | NZ185295A (pt) |
| PL (1) | PL110392B1 (pt) |
| PT (1) | PT67109B (pt) |
| SE (1) | SE431655B (pt) |
| SU (2) | SU743581A3 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2853785A1 (de) * | 1978-12-11 | 1980-06-19 | Schering Ag | Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung |
| JPH0374245A (ja) * | 1989-08-12 | 1991-03-28 | Mk Seiko Co Ltd | 洗車機 |
| CN106038476B (zh) | 2010-03-26 | 2020-04-17 | 盖尔德马研究及发展公司 | 安全和有效治疗红斑的改进的方法和组合物 |
| WO2013057579A2 (en) | 2011-10-19 | 2013-04-25 | Galderma Pharma S.A. | Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors |
| CN106632561A (zh) * | 2016-12-16 | 2017-05-10 | 广州仁恒医药科技股份有限公司 | 一种二氟泼尼酯的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH429716A (de) * | 1961-06-24 | 1967-02-15 | Vismara Francesco Spa | Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden |
| DE2055221A1 (en) * | 1970-11-10 | 1972-05-18 | Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) | 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride |
-
1977
- 1977-09-29 NZ NZ185295A patent/NZ185295A/xx unknown
- 1977-09-30 CH CH1199177A patent/CH630098A5/de not_active IP Right Cessation
- 1977-09-30 PL PL1977201161A patent/PL110392B1/pl unknown
- 1977-09-30 IL IL53030A patent/IL53030A/xx unknown
- 1977-10-03 IT IT28201/77A patent/IT1113623B/it active
- 1977-10-03 LU LU78223A patent/LU78223A1/xx unknown
- 1977-10-03 GR GR54473A patent/GR73041B/el unknown
- 1977-10-03 HU HU77SCHE624A patent/HU179593B/hu unknown
- 1977-10-03 GB GB40924/77A patent/GB1594852A/en not_active Expired
- 1977-10-03 PT PT67109A patent/PT67109B/pt unknown
- 1977-10-03 AT AT703577A patent/AT358202B/de not_active IP Right Cessation
- 1977-10-03 SE SE7711039A patent/SE431655B/xx not_active IP Right Cessation
- 1977-10-03 IE IE2011/77A patent/IE45877B1/en unknown
- 1977-10-03 NO NO773362A patent/NO148597C/no unknown
- 1977-10-04 ES ES462887A patent/ES462887A1/es not_active Expired
- 1977-10-04 DK DK438277A patent/DK438277A/da not_active Application Discontinuation
- 1977-10-04 NL NL7710869A patent/NL7710869A/xx not_active Application Discontinuation
- 1977-10-04 FR FR7729740A patent/FR2366313A1/fr active Granted
- 1977-10-04 JP JP11940077A patent/JPS5359654A/ja active Granted
- 1977-10-04 FI FI772922A patent/FI58645C/fi not_active IP Right Cessation
- 1977-10-04 SU SU772526300A patent/SU743581A3/ru active
-
1978
- 1978-10-13 SU SU782672298A patent/SU751327A3/ru active
-
1981
- 1981-09-08 CH CH579381A patent/CH632278A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579281A patent/CH632772A5/de not_active IP Right Cessation
- 1981-09-08 CH CH579481A patent/CH631997A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE45877B1 (en) | 1982-12-15 |
| PL201161A1 (pl) | 1979-01-29 |
| IT1113623B (it) | 1986-01-20 |
| FI58645B (fi) | 1980-11-28 |
| FI58645C (fi) | 1981-03-10 |
| SE7711039L (sv) | 1978-04-05 |
| CH632278A5 (en) | 1982-09-30 |
| GR73041B (pt) | 1984-01-26 |
| NO148597B (no) | 1983-08-01 |
| DK438277A (da) | 1978-04-05 |
| FR2366313A1 (fr) | 1978-04-28 |
| JPS5359654A (en) | 1978-05-29 |
| ATA703577A (de) | 1980-01-15 |
| NO773362L (no) | 1978-04-05 |
| AT358202B (de) | 1980-08-25 |
| JPS6129960B2 (pt) | 1986-07-10 |
| PL110392B1 (en) | 1980-07-31 |
| FI772922A (fi) | 1978-04-05 |
| LU78223A1 (pt) | 1978-02-01 |
| IE45877L (en) | 1978-04-04 |
| SU743581A3 (ru) | 1980-06-25 |
| NO148597C (no) | 1983-11-09 |
| ES462887A1 (es) | 1978-12-16 |
| PT67109A (de) | 1977-11-01 |
| GB1594852A (en) | 1981-08-05 |
| NL7710869A (nl) | 1978-04-06 |
| FR2366313B1 (pt) | 1980-02-01 |
| IL53030A0 (en) | 1977-11-30 |
| IL53030A (en) | 1982-11-30 |
| HU179593B (en) | 1982-11-29 |
| SE431655B (sv) | 1984-02-20 |
| SU751327A3 (ru) | 1980-07-23 |
| CH631997A5 (en) | 1982-09-15 |
| PT67109B (de) | 1979-03-14 |
| NZ185295A (en) | 1980-04-28 |
| CH632772A5 (en) | 1982-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |