CH628902A5 - Verfahren zur herstellung von 7-beta-(2-oxyimino-2-arylacetamido)-cephalosporinen. - Google Patents

Verfahren zur herstellung von 7-beta-(2-oxyimino-2-arylacetamido)-cephalosporinen. Download PDF

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Publication number
CH628902A5
CH628902A5 CH853477A CH853477A CH628902A5 CH 628902 A5 CH628902 A5 CH 628902A5 CH 853477 A CH853477 A CH 853477A CH 853477 A CH853477 A CH 853477A CH 628902 A5 CH628902 A5 CH 628902A5
Authority
CH
Switzerland
Prior art keywords
group
general formula
acid
mol
solution
Prior art date
Application number
CH853477A
Other languages
German (de)
English (en)
Inventor
George Lawrence Dunn
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of CH628902A5 publication Critical patent/CH628902A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH853477A 1976-07-12 1977-07-11 Verfahren zur herstellung von 7-beta-(2-oxyimino-2-arylacetamido)-cephalosporinen. CH628902A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/704,160 US4066762A (en) 1976-07-12 1976-07-12 Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
CH628902A5 true CH628902A5 (de) 1982-03-31

Family

ID=24828339

Family Applications (1)

Application Number Title Priority Date Filing Date
CH853477A CH628902A5 (de) 1976-07-12 1977-07-11 Verfahren zur herstellung von 7-beta-(2-oxyimino-2-arylacetamido)-cephalosporinen.

Country Status (25)

Country Link
US (1) US4066762A (es)
JP (1) JPS539792A (es)
AR (1) AR218454A1 (es)
AT (1) AT359187B (es)
AU (1) AU506092B2 (es)
BE (1) BE856636A (es)
CA (1) CA1120924A (es)
CH (1) CH628902A5 (es)
DE (1) DE2730377A1 (es)
DK (1) DK304977A (es)
ES (1) ES460595A1 (es)
FI (1) FI63586C (es)
FR (1) FR2361404A1 (es)
GB (1) GB1589094A (es)
HU (1) HU179586B (es)
IE (1) IE45452B1 (es)
IL (1) IL52466A (es)
LU (1) LU77711A1 (es)
MX (1) MX4972E (es)
NL (1) NL7707694A (es)
NO (1) NO152007C (es)
PH (1) PH13412A (es)
PT (1) PT66766B (es)
SE (1) SE437833B (es)
ZA (1) ZA773457B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171368A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4171433A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
IL50546A (en) * 1975-10-30 1980-07-31 Smithkline Corp 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
DE2760484C2 (es) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
US4101656A (en) * 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS55133385A (en) * 1979-04-03 1980-10-17 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, and remedy and preventive against microbism
SE434638B (sv) * 1980-06-06 1984-08-06 Lekemedelsfabriken Medica Ab Nya terapeutiska verdefulla taurinderivat och deras framstellning
US4308267A (en) * 1980-07-03 1981-12-29 Smithkline Corporation 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins
JPH0529868Y2 (es) * 1987-02-10 1993-07-30
JPS63134725U (es) * 1987-02-26 1988-09-05
EP2530073A4 (en) * 2010-01-27 2014-10-08 Mitsubishi Rayon Co NEW CHAIN TRANSFER AND EMULSION POLYMERIZATION THEREWITH

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL173169C (nl) * 1969-10-27 1983-12-16 Fujisawa Pharmaceutical Co Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking en werkwijze voor het bereiden van het daarvoor benodigde cephalosporinederivaat.
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
US3966717A (en) * 1971-05-14 1976-06-29 Glaxo Laboratories Limited 7-β-Acylamido-3-carbamoyloxymethylceph-3-em-4-carboxylic acids and salts thereof
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US3974153A (en) * 1971-05-14 1976-08-10 Glaxo Laboratories Limited 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
US3812110A (en) * 1972-02-24 1974-05-21 Squibb & Sons Inc 7-(1,4-cyclohexadienyl-acylamino)cephalosporins
AR207752A1 (es) * 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co Procedimiento para obtener acidos 7-amino-sustituido-3-tiometilsustituido-3-cefem-4-carboxilicos
IE42144B1 (en) * 1973-12-21 1980-06-18 Glaxo Lab Ltd Improvements in or relating to antibiotics
BE832725A (fr) * 1974-09-03 1976-02-25 Nouveaux composes meterocycliques et composition pharmaceutique les contenant
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
IE44607B1 (en) * 1975-03-18 1982-01-27 Smithkline Corp Cephalosporin compounds

Also Published As

Publication number Publication date
AU506092B2 (en) 1979-12-13
MX4972E (es) 1983-01-26
GB1589094A (en) 1981-05-07
HU179586B (en) 1982-11-29
NO152007C (no) 1985-07-17
DE2730377A1 (de) 1978-01-19
NO152007B (no) 1985-04-09
FI63586B (fi) 1983-03-31
IE45452L (en) 1978-01-12
IE45452B1 (en) 1982-08-25
JPS539792A (en) 1978-01-28
SE7708048L (sv) 1978-01-13
SE437833B (sv) 1985-03-18
AT359187B (de) 1980-10-27
PT66766B (en) 1978-12-15
FI772147A (es) 1978-01-13
LU77711A1 (es) 1977-10-05
BE856636A (fr) 1978-01-09
FR2361404A1 (fr) 1978-03-10
ATA495577A (de) 1980-03-15
AU2694177A (en) 1979-01-18
CA1120924A (en) 1982-03-30
JPS6156239B2 (es) 1986-12-01
PT66766A (en) 1977-08-01
ES460595A1 (es) 1978-05-01
NL7707694A (nl) 1978-01-16
DK304977A (da) 1978-01-13
IL52466A0 (en) 1977-10-31
US4066762A (en) 1978-01-03
FI63586C (fi) 1983-07-11
AR218454A1 (es) 1980-06-13
PH13412A (en) 1980-03-28
FR2361404B1 (es) 1980-11-28
ZA773457B (en) 1978-04-26
NO772431L (no) 1978-01-13
IL52466A (en) 1980-06-30

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