IL52466A - 7(2-acyl-2-hydroxyiminoacetamido)-3-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

7(2-acyl-2-hydroxyiminoacetamido)-3-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL52466A
IL52466A IL52466A IL5246677A IL52466A IL 52466 A IL52466 A IL 52466A IL 52466 A IL52466 A IL 52466A IL 5246677 A IL5246677 A IL 5246677A IL 52466 A IL52466 A IL 52466A
Authority
IL
Israel
Prior art keywords
hydroxyiminoacetamido
ylthiomethyl
cephem
tetrazol
acyl
Prior art date
Application number
IL52466A
Other languages
English (en)
Other versions
IL52466A0 (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of IL52466A0 publication Critical patent/IL52466A0/xx
Publication of IL52466A publication Critical patent/IL52466A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL52466A 1976-07-12 1977-07-06 7(2-acyl-2-hydroxyiminoacetamido)-3-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL52466A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/704,160 US4066762A (en) 1976-07-12 1976-07-12 Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Publications (2)

Publication Number Publication Date
IL52466A0 IL52466A0 (en) 1977-10-31
IL52466A true IL52466A (en) 1980-06-30

Family

ID=24828339

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52466A IL52466A (en) 1976-07-12 1977-07-06 7(2-acyl-2-hydroxyiminoacetamido)-3-tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US4066762A (es)
JP (1) JPS539792A (es)
AR (1) AR218454A1 (es)
AT (1) AT359187B (es)
AU (1) AU506092B2 (es)
BE (1) BE856636A (es)
CA (1) CA1120924A (es)
CH (1) CH628902A5 (es)
DE (1) DE2730377A1 (es)
DK (1) DK304977A (es)
ES (1) ES460595A1 (es)
FI (1) FI63586C (es)
FR (1) FR2361404A1 (es)
GB (1) GB1589094A (es)
HU (1) HU179586B (es)
IE (1) IE45452B1 (es)
IL (1) IL52466A (es)
LU (1) LU77711A1 (es)
MX (1) MX4972E (es)
NL (1) NL7707694A (es)
NO (1) NO152007C (es)
PH (1) PH13412A (es)
PT (1) PT66766B (es)
SE (1) SE437833B (es)
ZA (1) ZA773457B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171368A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4171433A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins
IL50546A (en) * 1975-10-30 1980-07-31 Smithkline Corp 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
DE2760484C2 (es) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
US4101656A (en) * 1976-07-12 1978-07-18 Smithkline Corporation 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS55133385A (en) * 1979-04-03 1980-10-17 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, and remedy and preventive against microbism
SE434638B (sv) * 1980-06-06 1984-08-06 Lekemedelsfabriken Medica Ab Nya terapeutiska verdefulla taurinderivat och deras framstellning
US4308267A (en) * 1980-07-03 1981-12-29 Smithkline Corporation 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins
JPH0529868Y2 (es) * 1987-02-10 1993-07-30
JPS63134725U (es) * 1987-02-26 1988-09-05
WO2011093401A1 (ja) 2010-01-27 2011-08-04 三菱レイヨン株式会社 新規連鎖移動剤及びそれを用いた乳化重合

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL173169C (nl) * 1969-10-27 1983-12-16 Fujisawa Pharmaceutical Co Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking en werkwijze voor het bereiden van het daarvoor benodigde cephalosporinederivaat.
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US3966717A (en) * 1971-05-14 1976-06-29 Glaxo Laboratories Limited 7-β-Acylamido-3-carbamoyloxymethylceph-3-em-4-carboxylic acids and salts thereof
US3974153A (en) * 1971-05-14 1976-08-10 Glaxo Laboratories Limited 7-Hydrocarbonoxy imino-acetamido-3-carbamoyloxy methylceph-3-em-4 carboxylic acids
US3812110A (en) * 1972-02-24 1974-05-21 Squibb & Sons Inc 7-(1,4-cyclohexadienyl-acylamino)cephalosporins
AR207752A1 (es) * 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co Procedimiento para obtener acidos 7-amino-sustituido-3-tiometilsustituido-3-cefem-4-carboxilicos
CH617703A5 (en) * 1973-12-21 1980-06-13 Glaxo Operations Ltd Process for the preparation of the syn-isomer or of a mixture of syn- and anti-isomers of novel antibiotically active 7 beta -acylamino-ceph-3-em-4-carboxylic acids
BE832725A (fr) * 1974-09-03 1976-02-25 Nouveaux composes meterocycliques et composition pharmaceutique les contenant
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
JPS51115493A (en) * 1975-03-18 1976-10-12 Smithkline Corp Novel cephalosporine compound

Also Published As

Publication number Publication date
HU179586B (en) 1982-11-29
NO152007B (no) 1985-04-09
US4066762A (en) 1978-01-03
ES460595A1 (es) 1978-05-01
FR2361404A1 (fr) 1978-03-10
SE7708048L (sv) 1978-01-13
ZA773457B (en) 1978-04-26
FR2361404B1 (es) 1980-11-28
DE2730377A1 (de) 1978-01-19
AU506092B2 (en) 1979-12-13
JPS6156239B2 (es) 1986-12-01
ATA495577A (de) 1980-03-15
CA1120924A (en) 1982-03-30
BE856636A (fr) 1978-01-09
LU77711A1 (es) 1977-10-05
CH628902A5 (de) 1982-03-31
PT66766A (en) 1977-08-01
FI772147A (es) 1978-01-13
MX4972E (es) 1983-01-26
AU2694177A (en) 1979-01-18
FI63586C (fi) 1983-07-11
NL7707694A (nl) 1978-01-16
DK304977A (da) 1978-01-13
SE437833B (sv) 1985-03-18
AT359187B (de) 1980-10-27
IL52466A0 (en) 1977-10-31
AR218454A1 (es) 1980-06-13
IE45452B1 (en) 1982-08-25
JPS539792A (en) 1978-01-28
NO772431L (no) 1978-01-13
GB1589094A (en) 1981-05-07
FI63586B (fi) 1983-03-31
NO152007C (no) 1985-07-17
IE45452L (en) 1978-01-12
PH13412A (en) 1980-03-28
PT66766B (en) 1978-12-15

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