CH619969A5 - Process for the preparation of new halogenated derivatives of the 16alpha-methylpregnane series - Google Patents

Process for the preparation of new halogenated derivatives of the 16alpha-methylpregnane series Download PDF

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Publication number
CH619969A5
CH619969A5 CH264177A CH264177A CH619969A5 CH 619969 A5 CH619969 A5 CH 619969A5 CH 264177 A CH264177 A CH 264177A CH 264177 A CH264177 A CH 264177A CH 619969 A5 CH619969 A5 CH 619969A5
Authority
CH
Switzerland
Prior art keywords
compounds
formula
prepared
atom
chlorine atom
Prior art date
Application number
CH264177A
Other languages
English (en)
French (fr)
Inventor
Jean Georges Teutsch
Germain Costerousse
Roger Deraedt
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of CH619969A5 publication Critical patent/CH619969A5/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH264177A 1976-03-02 1977-03-02 Process for the preparation of new halogenated derivatives of the 16alpha-methylpregnane series CH619969A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7605854A FR2342738A1 (fr) 1976-03-02 1976-03-02 Nouveaux derives halogenes de la serie du 16a-methyl pregnane

Publications (1)

Publication Number Publication Date
CH619969A5 true CH619969A5 (en) 1980-10-31

Family

ID=9169832

Family Applications (1)

Application Number Title Priority Date Filing Date
CH264177A CH619969A5 (en) 1976-03-02 1977-03-02 Process for the preparation of new halogenated derivatives of the 16alpha-methylpregnane series

Country Status (16)

Country Link
JP (1) JPS52106855A (ja)
AT (1) AT355237B (ja)
AU (1) AU509948B2 (ja)
BE (1) BE851944A (ja)
CA (1) CA1082170A (ja)
CH (1) CH619969A5 (ja)
DE (1) DE2709078C2 (ja)
DK (1) DK156401C (ja)
FR (1) FR2342738A1 (ja)
GB (1) GB1530975A (ja)
IE (1) IE44866B1 (ja)
LU (1) LU76867A1 (ja)
NL (1) NL7702166A (ja)
PT (1) PT66261B (ja)
SE (1) SE7702250L (ja)
ZA (1) ZA771078B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462443A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament
FR2533928A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB928302A (en) * 1958-06-20 1963-06-12 Scherico Ltd í¸-pregnene compounds
US3049554A (en) * 1959-06-01 1962-08-14 Schering Corp 9, 11-dihalogeno-3, 20-diketopregnanes and processes for their manufacture

Also Published As

Publication number Publication date
AT355237B (de) 1980-02-25
PT66261B (fr) 1979-01-17
NL7702166A (nl) 1977-09-06
DK88277A (da) 1977-09-03
CA1082170A (fr) 1980-07-22
IE44866L (en) 1977-09-02
IE44866B1 (en) 1982-04-21
GB1530975A (en) 1978-11-01
SE7702250L (sv) 1977-09-03
DK156401B (da) 1989-08-14
FR2342738A1 (fr) 1977-09-30
JPS6150960B2 (ja) 1986-11-06
DE2709078C2 (de) 1986-09-11
FR2342738B1 (ja) 1979-10-12
DK156401C (da) 1990-01-08
PT66261A (fr) 1977-04-01
LU76867A1 (ja) 1977-09-26
AU509948B2 (en) 1980-06-05
ZA771078B (en) 1978-04-26
ATA136577A (de) 1979-07-15
DE2709078A1 (de) 1977-09-08
AU2280877A (en) 1978-09-07
JPS52106855A (en) 1977-09-07
BE851944A (fr) 1977-09-01

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