CH618686A5 - - Google Patents

Download PDF

Info

Publication number
CH618686A5
CH618686A5 CH831576A CH831576A CH618686A5 CH 618686 A5 CH618686 A5 CH 618686A5 CH 831576 A CH831576 A CH 831576A CH 831576 A CH831576 A CH 831576A CH 618686 A5 CH618686 A5 CH 618686A5
Authority
CH
Switzerland
Prior art keywords
lofepramine
hydrochloride
acetate
solvent
propyl
Prior art date
Application number
CH831576A
Other languages
German (de)
English (en)
Inventor
Edgar Eriksoo
Sten Sture Kelfve
Original Assignee
Leo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Ab filed Critical Leo Ab
Publication of CH618686A5 publication Critical patent/CH618686A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH831576A 1975-07-03 1976-06-29 CH618686A5 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28145/75A GB1497306A (en) 1975-07-03 1975-07-03 Preparation of lofepramine and its hydrochloride

Publications (1)

Publication Number Publication Date
CH618686A5 true CH618686A5 (nl) 1980-08-15

Family

ID=10270996

Family Applications (1)

Application Number Title Priority Date Filing Date
CH831576A CH618686A5 (nl) 1975-07-03 1976-06-29

Country Status (10)

Country Link
US (1) US4172074A (nl)
JP (1) JPS6014030B2 (nl)
BE (1) BE843691A (nl)
CA (1) CA1079274A (nl)
CH (1) CH618686A5 (nl)
DE (1) DE2628558A1 (nl)
FR (1) FR2316234A1 (nl)
GB (1) GB1497306A (nl)
IE (1) IE43255B1 (nl)
SE (1) SE7607565L (nl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4108119A1 (de) * 1991-03-13 1992-09-17 Jellalabad Ltd Verfahren zur herstellung von 4'-chlor-2-((3-(10,11-dihydro-5h-dibenz(b,f)azepin-5-yl)propyl) methylaminno) acetophenon und seiner salze, die stabilisierungseiner salze, hierbei erhaeltliche produkte und pharmmazeutische zubereitungen, die diese enthalten
SK281932B6 (sk) * 1994-10-05 2001-09-11 Cari Loder Použitie kombinácie tricyklického antidepresíva alebo inhibítora monoaminooxidázy s aminokyselinovou zlúčeninou indukujúcou neurotransmiter
GB2308065B (en) * 1994-10-05 1999-01-13 Cari Loder Treatment of multiple sclerosis (MS) and other demyelinating conditions
ES2515092T3 (es) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión
WO2006038084A1 (en) * 2004-10-01 2006-04-13 Neurocure Ltd Use of pharmaceutical compositions of lofepramine for the treatment of adhd, cfs, fm and depression
CA2614289A1 (en) 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008083204A2 (en) * 2006-12-28 2008-07-10 Braincells, Inc. Modulation of neurogenesis by melatoninergic ligands
WO2008086483A2 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation of neurogenesis with use of modafinil
WO2009128058A1 (en) 2008-04-18 2009-10-22 UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al Psycho-pharmaceuticals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1177525A (en) * 1967-04-13 1970-01-14 Leo Ab New Heterocyclic Aminoketones of Therapeutic Interest

Also Published As

Publication number Publication date
US4172074A (en) 1979-10-23
DE2628558A1 (de) 1977-01-20
JPS527982A (en) 1977-01-21
BE843691A (fr) 1977-01-03
GB1497306A (en) 1978-01-05
CA1079274A (en) 1980-06-10
JPS6014030B2 (ja) 1985-04-11
FR2316234B1 (nl) 1979-06-08
FR2316234A1 (fr) 1977-01-28
DE2628558C2 (nl) 1989-11-16
IE43255B1 (en) 1981-01-14
SE7607565L (sv) 1977-01-04
IE43255L (en) 1977-01-03

Similar Documents

Publication Publication Date Title
DE2628558C2 (nl)
DE1962757C3 (de) Evomonosid-Derivate, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
DE2404946C3 (de) Verfahren zur Herstellung von 7alpha-Acylthio-Steroidspirolactonen
DE2318767C3 (de) Triamcinolon-Derivat, Verfahren zu seiner Herstellung und dieses enthaltende Arzneimittel
DE1912941C3 (de) 1 -Phenyl^-amino-e-methoxypyridaziniumsalze
DE3026602A1 (de) 14-oxo-15-halogen-e-homoeburnanderivate, verfahren zur herstellung derselben und von 14-oxo-15-hydroxyimino-e-homoeburnanderivaten und die ersteren enthaltende arzneimittel
DE1695212B2 (de) Verfahren zur Herstellung von Iodininderivaten
AT326638B (de) Verfahren zur herstellung von n(beta-diäthylaminoäthyl) -4-amino-5-chlor-2-methoxybenzamid
DE1960130A1 (de) Neue Verfahren zur Herstellung von N-(Diaethylaminoaethyl)-4-amino-5-chloro-2-methoxybenzamid
DE2331044A1 (de) Diphenylmethan-derivate und verfahren zu deren herstellung
DE2236005C3 (de) Dibenzo- eckige Klammer auf d,f eckige Klammer zu -dioxepin- eckige Klammer auf 1,3 eckige Klammer zu -derivate und deren pharmakologisch verträgliche Salze, sowie Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE1092932B (de) Verfahren zur Herstellung amoebicid wirksamer N-Dichloracet-oxy-anilid-Ester
DE2166662A1 (de) Tricyclische derivate von aliphatischen omega-alkoholen und verfahren zu ihrer herstellung
DE2403682C3 (de) S-Methyl-Z-phenyl-S-benzothiazolln-esslgsäure-Verbindungen und Verfahren zu ihrer Herstellung
DE1929237A1 (de) Verfahren zur Herstellung von N-Acyl-3,4-epoxy-pyrrolidin-Derivaten
DE2218190C3 (nl)
DE1002347C2 (de) Verfahren zur Herstellung von in 4(5)-Stellung ungesaettigten 2-Jodsteroid-3-ketonen bzw. Steroid-3-ketonen
EP0150411A1 (de) Verfahren zur Herstellung substituierter Chinazolin-2.4(1H.3H)-dione
AT239226B (de) Verfahren zur Herstellung von neuen, substituierten 2-Oxo-tetrahydrochinolinen
AT209007B (de) Verfahren zur Herstellung von 9 α-Halogen-4-pregnen-16 α, 17 α,21-triol-3, 11, 20-trionen und ihren Estern
DE3511149A1 (de) Verfahren zur herstellung von 2,2-bis-halogenmethylpenam-derivaten
DE1966212A1 (de) Neue Verfahren zur Herstellung von N-(Diaethylaminoaethyl)-4-amino-5-chloro-2-methoxybenzamid
DE3431009A1 (de) Verfahren zur herstellung von 6-demethyl-6-desoxy-6-methylen-5-oxytetracyclin und dessen 11a-chlorderivat
DE1145617B (de) Verfahren zur Herstellung von Trialkoxybenzoesaeureestern des 3-Chlor-10-{3-[4-(ª‰-oxyaethyl)-piperazino]-propyl}-phenthiazins
DE2023048A1 (de) Verfahren zur Herstellung von 4,5 alpha-Oxido-bufa-dienolid-3-[rhamnosido-2',3'-dialkylorthocarbonaten]

Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: PHARMACIA BIOSYSTEMS AB

PUE Assignment

Owner name: PHARMACIA AKTIEBOLAG

PL Patent ceased