CH441276A - Verfahren zur Herstellung des neuen 3,5-Bis-trifluormethyl-4'-nitro-thiocarbanilids - Google Patents
Verfahren zur Herstellung des neuen 3,5-Bis-trifluormethyl-4'-nitro-thiocarbanilidsInfo
- Publication number
- CH441276A CH441276A CH1689365A CH1689365A CH441276A CH 441276 A CH441276 A CH 441276A CH 1689365 A CH1689365 A CH 1689365A CH 1689365 A CH1689365 A CH 1689365A CH 441276 A CH441276 A CH 441276A
- Authority
- CH
- Switzerland
- Prior art keywords
- bis
- trifluoromethyl
- new
- preparation
- nitro
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 7
- 238000002360 preparation method Methods 0.000 title claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 10
- FXOSSGVJGGNASE-UHFFFAOYSA-N 1-isothiocyanato-3,5-bis(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=CC(N=C=S)=CC(C(F)(F)F)=C1 FXOSSGVJGGNASE-UHFFFAOYSA-N 0.000 claims description 3
- TYMLOMAKGOJONV-UHFFFAOYSA-N 4-nitroaniline Chemical compound NC1=CC=C([N+]([O-])=O)C=C1 TYMLOMAKGOJONV-UHFFFAOYSA-N 0.000 claims description 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 2
- 125000003277 amino group Chemical group 0.000 claims description 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N aminothiocarboxamide Natural products NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims description 2
- 238000009833 condensation Methods 0.000 claims description 2
- 230000005494 condensation Effects 0.000 claims description 2
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 3
- 241000242722 Cestoda Species 0.000 description 2
- 241000242711 Fasciola hepatica Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 241000244160 Echinococcus Species 0.000 description 1
- 241000545744 Hirudinea Species 0.000 description 1
- 241000404582 Hymenolepis <angiosperm> Species 0.000 description 1
- 241001137878 Moniezia Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000000507 anthelmentic effect Effects 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012050 conventional carrier Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 208000006275 fascioliasis Diseases 0.000 description 1
- 206010016235 fasciolopsiasis Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1288563 | 1965-01-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH441276A true CH441276A (de) | 1967-08-15 |
Family
ID=10012913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1689365A CH441276A (de) | 1965-01-05 | 1965-01-15 | Verfahren zur Herstellung des neuen 3,5-Bis-trifluormethyl-4'-nitro-thiocarbanilids |
Country Status (6)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3235815A1 (de) * | 2016-04-19 | 2017-10-25 | Philipps-Universität Marburg | Wirkstoffe gegen parasitäre helminthen |
-
1965
- 1965-01-15 CH CH1689365A patent/CH441276A/de unknown
- 1965-12-10 AT AT1112265A patent/AT256876B/de active
-
1966
- 1966-01-04 NL NL6600056A patent/NL6600056A/xx unknown
- 1966-01-04 BE BE674718D patent/BE674718A/xx unknown
- 1966-01-04 OA OA52308A patent/OA01886A/xx unknown
- 1966-03-17 FR FR53792A patent/FR5534M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR5534M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-11-13 |
| AT256876B (de) | 1967-09-11 |
| NL6600056A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-07-06 |
| BE674718A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-07-04 |
| OA01886A (fr) | 1970-02-04 |
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