CA3082380C - Recombinant cells comprisng exogenous .delta.6 desaturase and methods for producing oil containing unsaturated fatty acids - Google Patents

Recombinant cells comprisng exogenous .delta.6 desaturase and methods for producing oil containing unsaturated fatty acids

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Publication number
CA3082380C
CA3082380C CA3082380A CA3082380A CA3082380C CA 3082380 C CA3082380 C CA 3082380C CA 3082380 A CA3082380 A CA 3082380A CA 3082380 A CA3082380 A CA 3082380A CA 3082380 C CA3082380 C CA 3082380C
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Prior art keywords
cell
desaturase
plant
seq
fatty acid
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CA3082380A
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English (en)
French (fr)
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CA3082380A1 (en
Inventor
Anne Maree Mackenzie
Qing Liu
Pushkar Shrestha
Peter David Nichols
Susan Irene Ellis Blackburn
Maged Peter Mansour
Stanley Suresh Robert
Dion Matthew Frederick Frampton
Xue-Rong Zhou
Surinder Pal Singh
Craig Christopher Wood
James Robertson Petrie
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Commonwealth Scientific and Industrial Research Organisation
Grains Research and Development Corporation
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Priority to CA3082380A priority Critical patent/CA3082380C/en
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
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Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO347177B1 (no) 2003-08-01 2023-06-19 Basf Plant Science Gmbh Fremgangsmåte for fremstilling av flerumettede fettsyrer i transgene organismer
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
CA3056110C (en) 2004-04-22 2020-07-14 Surinder Pal Singh Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
WO2008006171A1 (en) 2006-07-14 2008-01-17 Commonwealth Scientific And Industrial Research Organisation Altering the fatty acid composition of rice
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
WO2009129582A1 (en) * 2008-04-25 2009-10-29 Commonwealth Scientific Industrial Research Organisation Polypeptides and methods for producing triacylglycerols comprising modified fatty acids
CA2722276A1 (en) * 2008-04-25 2009-10-29 Commonwealth Scientific Industrial Research Organisation Recombinant cells and methods for hydroxylating fatty acids
WO2010009500A1 (en) 2008-07-21 2010-01-28 Commonwealth Scientific And Industrial Research Organisation Improved vegetable oils and uses therefor
CN102202498B (zh) 2008-07-21 2016-09-07 澳大利亚联邦科学与工业研究组织 改良的棉籽油及应用
DK2358882T3 (da) * 2008-11-18 2017-11-06 Commw Scient Ind Res Org Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer
CA3161358A1 (en) * 2009-07-17 2011-01-20 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
CA2804025C (en) 2010-06-28 2023-02-21 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids
EP2630235B1 (en) * 2010-10-21 2017-04-05 BASF Plant Science Company GmbH Novel fatty acid desaturases, elongases, elongation components and uses therof
RU2556375C1 (ru) * 2011-08-04 2015-07-10 Сантори Холдингз Лимитед Белок, обладающий активностью в отношении стимуляции элонгации цепей жирных кислот, кодирующий его ген и их применение
CA2860416C (en) 2011-12-27 2024-04-30 Commonwealth Scientific And Industrial Research Organisation Production of dihydrosterculic acid and derivatives thereof
PH12014501474B1 (en) 2011-12-27 2024-01-19 Nuseed Global Innovation Ltd Processes for producing lipids
EP2798065B1 (en) 2011-12-27 2019-06-05 Commonwealth Scientific and Industrial Research Organisation Simultaneous gene silencing and supressing gene silencing in the same cell
US8809026B2 (en) 2011-12-27 2014-08-19 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
US11639507B2 (en) 2011-12-27 2023-05-02 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
AU2013246661B2 (en) * 2012-04-12 2018-12-20 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
HK1207938A1 (en) 2012-04-25 2016-02-19 Commonwealth Scientific And Industrial Research Organisation High oleic acid oils
US8946460B2 (en) 2012-06-15 2015-02-03 Commonwealth Scientific And Industrial Research Organisation Process for producing polyunsaturated fatty acids in an esterified form
US20140090108A1 (en) * 2012-09-18 2014-03-27 Freydoun Garabagi Vectors and Methods For Enhancing Recombinant Protein Expression in Plants
GB201217524D0 (en) * 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
CN102978177B (zh) * 2012-11-09 2015-06-03 浙江工业大学 冬虫夏草合成代谢二十碳五烯酸的△-5-脱氢酶、基因及应用
CN103173445B (zh) * 2013-04-15 2014-07-30 南京江辉生物科技有限公司 一种欧米伽3的合成基因、含有合成基因的大肠菌及其构建方法
RU2016100762A (ru) * 2013-06-14 2017-07-20 Джей.Ар. СИМПЛОТ КОМПАНИ Продукция белка в растениях
US11718577B2 (en) 2013-12-18 2023-08-08 Commonwealth Scientific And Industrial Research Organisation Lipid compositions comprising triacylglycerol with long-chain polyunsaturated fatty acids
WO2015196250A1 (en) 2014-06-27 2015-12-30 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid
KR102386838B1 (ko) 2013-12-18 2022-04-15 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 장쇄 다중불포화 지방산을 포함하는 지질
CN113980730B (zh) * 2014-06-27 2025-05-27 联邦科学技术研究组织 包含二十二碳五烯酸的提取的植物脂质
EA037184B1 (ru) * 2014-06-27 2021-02-16 Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн Липид, содержащий докозапентаеновую кислоту
MY204560A (en) 2014-07-07 2024-09-04 Nuseed Global Innovation Ltd Process for producing industrial products from plant lipids
WO2016075326A2 (en) 2014-11-14 2016-05-19 Basf Plant Science Company Gmbh Materials and methods for pufa production, and pufa-containing compositions
US20180122021A1 (en) * 2015-03-03 2018-05-03 Uop Llc Chemical refinery performance optimization
JP2019129705A (ja) 2016-03-31 2019-08-08 日本たばこ産業株式会社 植物に物質を導入する方法
WO2017191165A1 (en) * 2016-05-03 2017-11-09 Lonza Ltd Modulation of lipid metabolism for protein production
AR109245A1 (es) * 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
EP3462902A4 (en) 2016-06-01 2020-03-04 Cargill, Incorporated FISH FOOD PREPARED FROM OLEAGINOUS PLANTS PRODUCING OMEGA-3 FATTY ACIDS
US10563218B2 (en) * 2016-06-16 2020-02-18 Nuseed Pty Ltd Inbred transgenic canola line NS-B50027-4 and seeds thereof
WO2018039740A1 (en) 2016-09-02 2018-03-08 Commonwealth Scientific And Industrial Research Organisation Plants with modified traits
EP3516066A1 (en) 2016-09-23 2019-07-31 Wake Forest University Modified microorganisms as sustainable sources of omega-3 polyunsaturated fatty acid production
IL268466B2 (en) 2017-02-06 2025-07-01 Commw Scient Ind Res Org Expression of nitrogenase polypeptides in plant cells
US11913006B2 (en) 2018-03-16 2024-02-27 Nuseed Global Innovation Ltd. Plants producing modified levels of medium chain fatty acids
CN108220167A (zh) * 2018-04-10 2018-06-29 中盐工程技术研究院有限公司 盐藻纯化分离方法及微藻纯化分离方法
JP7089603B2 (ja) 2018-06-11 2022-06-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 眼疾患を治療するための脱メチル化
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586641A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
EP3586643A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
KR102932345B1 (ko) 2019-03-08 2026-02-27 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 식물 세포에서 니트로게나제 폴리펩티드의 발현
US10916099B2 (en) * 2019-06-04 2021-02-09 Igt Gaming system and method with guaranteed symbol generation
US10896579B2 (en) * 2019-06-04 2021-01-19 Igt Gaming system and method with dynamically determined guaranteed awards
CN110218777B (zh) * 2019-06-14 2023-05-16 苏州天合优才生物科技有限公司 Pcr预混液
AU2020370081A1 (en) * 2019-10-25 2022-06-02 Nuseed Pty Ltd. Enriched polyunsaturated fatty acid compositions
WO2022015699A1 (en) * 2020-07-14 2022-01-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods to produce very long chain fatty acids
EP4289957A4 (en) 2021-02-05 2024-12-25 Nissui Corporation ULTRA-LONG CHAIN POLYUNSATURATED FATTY ACID COMPOSITION
AU2022419399A1 (en) * 2021-12-20 2024-06-27 Commonwealth Scientific And Industrial Research Organisation Plants for producing cannabinoids
JP7809524B2 (ja) * 2022-01-11 2026-02-02 花王株式会社 脂質の製造方法
CN119614625A (zh) * 2025-02-17 2025-03-14 中国热带农业科学院三亚研究院 芜菁皱缩病毒蛋白p38在调控拟南芥双链结合蛋白上的应用

Family Cites Families (258)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
WO1984002913A1 (en) 1983-01-17 1984-08-02 Monsanto Co Chimeric genes suitable for expression in plant cells
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
ATE100141T1 (de) 1984-03-06 1994-01-15 Mgi Pharma Inc Herbizide resistenz in pflanzen.
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
CA1338902C (en) 1986-02-27 1997-02-11 Howard M. Goodman Plant cells resistant to herbicidal glutamine synthetase inhibitors
MA20977A1 (fr) 1986-05-19 1987-12-31 Ciba Geigy Ag Plantes tolerant les herbicides contenant le gene de gluthathione S-Transferase
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5177010A (en) 1986-06-30 1993-01-05 University Of Toledo Process for transforming corn and the products thereof
SE455438B (sv) 1986-11-24 1988-07-11 Aga Ab Sett att senka en brennares flamtemperatur samt brennare med munstycken for oxygen resp brensle
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
CN87100603A (zh) 1987-01-21 1988-08-10 昂科公司 抗黑素瘤疫苗
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5932479A (en) 1988-09-26 1999-08-03 Auburn University Genetic engineering of plant chloroplasts
HU218465B (hu) 1989-08-09 2000-09-28 Dekalb Genetics Corporation Eljárások és kompozíciók stabilan transzformált, termő egyszikű növények és sejtjeik előállítására
EP0472712B1 (en) 1990-03-16 2001-09-12 Calgene LLC Novel sequences preferentially expressed in early seed development and methods related thereto
US5877402A (en) 1990-05-01 1999-03-02 Rutgers, The State University Of New Jersey DNA constructs and methods for stably transforming plastids of multicellular plants and expressing recombinant proteins therein
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US7135614B1 (en) 1990-08-30 2006-11-14 Cargill, Incorporated Brassica or helianthus plants having mutant delta-12 or delta-15 sequences
US5861187A (en) 1990-08-30 1999-01-19 Cargill, Incorporated Oil from canola seed with altered fatty acid profiles and a method of producing oil
US5518908A (en) 1991-09-23 1996-05-21 Monsanto Company Method of controlling insects
US6355861B1 (en) 1991-10-10 2002-03-12 Rhone-Poulenc Agrochimie Production of gamma linolenic acid by a Δ6-desaturase
US6683232B1 (en) 1991-10-10 2004-01-27 Rhone-Poulenc Agrochimie Production of γ linolenic acid by a Δ6-desaturase
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
CA2124673C (en) 1991-12-04 2008-08-05 John Browse Fatty acid desaturase genes from plants
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
US5683898A (en) 1992-05-15 1997-11-04 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
EP0594868A4 (en) 1992-05-15 1997-01-02 Sagami Chem Res Gene which codes for eicosapentaenoic acid synthetase group and process for producing eicosapentaenoic acid
US5798259A (en) 1992-05-15 1998-08-25 Sagami Chemical Research Center Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid
US6872872B1 (en) 1992-11-17 2005-03-29 E. I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
EP0688160B1 (en) 1993-03-11 1998-05-13 National Research Council Of Canada Enhanced regeneration system for cereals
CA2092588C (en) 1993-03-26 2008-07-08 Narender S. Nehra Enhanced regeneration system for cereals
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
GB9515941D0 (en) 1995-08-03 1995-10-04 Zeneca Ltd DNA constructs
US5939288A (en) 1995-06-07 1999-08-17 Iowa State University Research Foundation, Inc. Plant secretory signal peptides and nectarins
US6342658B1 (en) 1995-12-14 2002-01-29 Cargill, Incorporated Fatty acid desaturases and mutant sequences thereof
US7541519B2 (en) 1995-12-14 2009-06-02 Cargill, Incorporated Fatty acid desaturases and mutant sequences thereof
AU1293297A (en) 1995-12-14 1997-07-03 Cargill Incorporated Plants having mutant sequences that confer altered fatty acid profiles
CZ86798A3 (cs) 1996-06-21 1999-03-17 Monsanto Company Fertilní transgenní rostlina pšenice, způsob její přípravy, buňky a semena této rostliny
EP0913473A4 (en) 1996-07-10 2000-12-06 Sagami Chem Res METHOD FOR PRODUCING EICOSAPENTIC ACID BY GENETIC RECOMBINATION
US7109392B1 (en) 1996-10-09 2006-09-19 Cargill, Incorporated Methods for increasing oleic acid content in seeds from transgenic plants containing a mutant delta 12 desaturase
WO1998018952A1 (en) 1996-10-30 1998-05-07 Nippon Suisan Kaisha, Ltd. Process for producing fats containing highly unsaturated fatty acids containing selectively concentrated docosahexaenoic acid
US6194167B1 (en) 1997-02-18 2001-02-27 Washington State University Research Foundation ω-3 fatty acid desaturase
ATE408701T1 (de) 1997-03-04 2008-10-15 Suntory Ltd Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6075183A (en) 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
EP1598422B1 (en) 1997-04-11 2013-01-02 Calgene LLC Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US7589253B2 (en) 1997-04-15 2009-09-15 Commonwealth Scientific And Industrial Research Organisation Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism
US6235529B1 (en) 1997-04-29 2001-05-22 The Regents Of The University Of California Compositions and methods for plant transformation and regeneration
CA2283422A1 (en) 1997-06-04 1998-12-10 Calgene, Llc Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
WO1998056239A1 (en) 1997-06-12 1998-12-17 Cargill, Incorporated Fatty acid desaturases and mutant sequences thereof
AU8583798A (en) 1997-07-23 1999-02-16 Centro De Investigacion Y De Estudios Avanzados Del I.P.N. Improved plastid transformation of higher plants and production of trans genic plants with herbicide resistance
ATE417924T1 (de) 1997-09-12 2009-01-15 Commw Scient Ind Res Org Regulation der genexpression in pflanzen
DE69836552T3 (de) 1997-09-30 2014-10-09 The Regents Of The University Of California Herstellung von proteinen in pflanzensamen
EP1037837A4 (en) 1997-10-01 2004-03-10 Busse Bros Inc MACHINING SYSTEM FOR CONTAINERS
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
CA2315297A1 (en) 1997-12-23 1999-07-08 University Of Bristol Desaturase
US20030152983A1 (en) 1997-12-23 2003-08-14 University Of Bristol Desaturase
US6100447A (en) 1998-02-12 2000-08-08 Applied Phytologics, Inc. Method of barley transformation
US6838594B1 (en) 1998-03-20 2005-01-04 E. I. Du Pont De Nemours And Company Limnanthes oil genes
BR9908381A (pt) 1998-03-20 2002-06-11 Du Pont Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdio, processo de alteração do nìvel de expressão de uma enzima, método de produção de um ácido graxo dessaturado, semente, óleo, método de produção de óleo de semente, método de obtenção de um fragmento de ácido nucléico e produto
US6492108B1 (en) 1998-03-26 2002-12-10 Incyte Genomics, Inc. Delta-6 desaturase homologs
CA2329159A1 (en) 1998-05-29 1999-12-02 Bruce Kelder Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
DE69937050T2 (de) 1998-06-12 2008-05-29 Calgene Llc, Davis Polyungesättigte fettsäuren in pflanzen
AU4564399A (en) 1998-06-12 1999-12-30 Abbott Laboratories Polyunsaturated fatty acids in plants
BR9913382A (pt) 1998-08-20 2001-09-25 Du Pont Fragmentos de ácido nucléico isolados codificadores de uma enzima modificadora de ácidos graxos vegetais associada com a formação de uniões duplas conjugadas, genes quiméricos, células hospedeiras transformadas, sementes, óleos, métodos de alteração do nìvel de ácidos graxos com uniões duplas conjugadas em uma célula hospedeira, métodos de produção de óleo de sementes contendo ácidos graxos com uniões duplas conjugadas nas sementes de plantas, métodos de produção de enzimas modificadoras de ácidos graxos associadas com a formação de uniões duplas conjugadas, métodos de isolamento de fragmentos de ácidos nucléicos e seus subfragmentos funcionalmente equivalentes codificadores de uma enzima modificadora de ácidos graxos vegetais associada a formação de uniões duplas conjugadas, alimento animal, métodos de aprimoramento da qualidade de carcaça de um animal e complemento
AU5785199A (en) 1998-08-24 2000-03-14 Rutgers, The State University Of New Jersey Synthetic fatty acid desaturase gene for expression in plants
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
US6913916B1 (en) 1998-09-02 2005-07-05 Abbott Laboratories Elongase genes and uses thereof
US6677145B2 (en) 1998-09-02 2004-01-13 Abbott Laboratories Elongase genes and uses thereof
US20030163845A1 (en) 1998-09-02 2003-08-28 Pradip Mukerji Elongase genes and uses thereof
AU6503699A (en) 1998-10-05 2000-04-26 Abbott Laboratories Altered fatty acid biosynthesis in insect cells using delta five desaturase
WO2000020602A2 (en) 1998-10-05 2000-04-13 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
JP2002527051A (ja) 1998-10-09 2002-08-27 メルク エンド カムパニー インコーポレーテッド デルタ6脂肪酸デサチュラーゼ
JP4182192B2 (ja) 1998-11-26 2008-11-19 独立行政法人産業技術総合研究所 イコサペンタエン酸及び/又はドコサヘキサエン酸の生合成に関与する酵素群をコードする遺伝子
US6864077B1 (en) 1998-12-03 2005-03-08 Edgar B. Cahoon Membrane-bound desaturases
JP2001095588A (ja) 1998-12-04 2001-04-10 Research Institute Of Innovative Technology For The Earth 緑藻のω3脂肪酸不飽和化酵素遺伝子及びその利用
US6825017B1 (en) 1998-12-07 2004-11-30 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7271315B2 (en) 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US20070244192A1 (en) 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
EP1159435A1 (en) * 1999-03-05 2001-12-05 Monsanto Technology LLC Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
EP1035207A1 (en) 1999-03-09 2000-09-13 MultiGene Biotech GmbH cDNA molecules of the members of gene family encoding human fatty acid desaturases and their use in diagnosis and therapy
WO2000055330A1 (en) 1999-03-18 2000-09-21 The University Of Bristol Polysaturated fatty acid (pufa) elongase from caenorhabditis elegans
AU776447B2 (en) 1999-06-07 2004-09-09 Basf Plant Science Gmbh Delta6-acetylenase and delta6-desaturase from ceratodon purpureus
CA2378423A1 (en) 1999-07-06 2001-01-11 Basf Plant Science Gmbh Plants expressing .delta.6-desaturase genes and oils from these plants containing pufas and method for producing unsaturated fatty acids
AU6091600A (en) 1999-07-12 2001-01-30 Ohio University Mammalian cells expressing desaturases and elongases
US7070970B2 (en) 1999-08-23 2006-07-04 Abbott Laboratories Elongase genes and uses thereof
US7531718B2 (en) 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
CN1378602A (zh) 1999-08-26 2002-11-06 卡尔根尼有限公司 含修饰的多不饱和脂肪酸的植物
US7067722B2 (en) 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
AU7285300A (en) 1999-09-10 2001-04-17 Celanese Ventures Gmbh Nucleic acid which is obtained from tetrahymena and which codes for a delta-6-desaturase, the production thereof and use
FR2798391B1 (fr) 1999-09-15 2001-12-14 Inst Nat Sante Rech Med Enzyme thyroidienne nadph oxydase, acide nucleique codant pour cette enzyme et leurs applications
DE19950589A1 (de) 1999-10-20 2001-05-23 Gvs Ges Fuer Erwerb Und Verwer Elongasepromotoren für gewebespezifische Expression von Transgenen in Pflanzen
JP4221476B2 (ja) 1999-11-19 2009-02-12 独立行政法人産業技術総合研究所 イコサペンタエン酸生合成遺伝子群をクローニングしたプラスミド及びイコサペンタエン酸を産生するラン藻
ATE460490T1 (de) * 1999-11-22 2010-03-15 Plant Bioscience Ltd Erhöhte expression von transgenen durch co- exprimierung mit einen suppressor der post- transkriptionelle genabschaltung (ptgs)
AU1499601A (en) 1999-11-25 2001-06-04 Basf Plant Science Gmbh Moss genes from physcomitrella patents encoding proteins involved in the synthesis of polyunsaturated fatty acids and lipids
JP2001169780A (ja) 1999-12-15 2001-06-26 Natl Inst Of Advanced Industrial Science & Technology Meti ドコサヘキサエン酸生産細菌の遺伝子
GB9929897D0 (en) 1999-12-18 2000-02-09 Slabas Antoni R Improvements in or relating to conjugated fatty acids and related compounds
US20030172398A1 (en) 1999-12-21 2003-09-11 Browse John A. Novel delta-12 desaturase and methods of using it for synthesis of polyunsaturated fatty acids
US7544859B2 (en) 2000-02-09 2009-06-09 Basf Aktiengesellschaft Elongase gene and method for producing multiple-unsaturated fatty acids
US20040157221A9 (en) 2000-03-07 2004-08-12 Millennium Pharmaceuticals, Inc. Novel 25869, 25934, 26335, 50365, 21117, 38692, 46508, 16816, 16839, 49937, 49931 and 49933 molecules and uses therefor
US7411054B2 (en) 2000-03-07 2008-08-12 Millennium Pharmaceuticals, Inc. 25869, 25934, 26335, 50365, 21117, 38692, 46508, 16816, 16839, 49937, 49931 and 49933 molecules and uses therefor
US6686185B1 (en) 2000-03-07 2004-02-03 Millennium Pharmaceuticals, Inc. 25934, a novel fatty acid desaturase and uses therefor
US6492577B1 (en) 2000-03-16 2002-12-10 The Regents Of The University Of California Leafy cotyledon2 genes and their uses
EP1268818A2 (en) 2000-03-24 2003-01-02 Millennium Pharmaceuticals, Inc. 18221, dual specificity phosphatase and uses thereof
CA2301158A1 (en) 2000-03-24 2001-09-24 Stephen J. Allen Screening methods for compounds useful for modulating lipid metabolism in disease
WO2001075069A1 (en) 2000-03-31 2001-10-11 Idemitsu Petrochemical Co., Ltd. Process for producing lipids and lipid-secreting microorganisms
ATE476514T1 (de) 2000-04-18 2010-08-15 Commw Scient Ind Res Org Verfahren zur modifizierung des baumwollölgehaltes
AU2001266579A1 (en) 2000-05-16 2001-11-26 Dario B. Crosetto Method and apparatus for anatomical and functional medical imaging
US7091005B2 (en) 2000-05-16 2006-08-15 Merck & Co., Inc. Gene responsible for Stargardt-like dominant macular dystrophy
EP1404820A2 (en) 2000-05-19 2004-04-07 Millennium Pharmaceuticals, Inc. 50365, a hexokinase family member and uses therefor
WO2001092489A2 (en) 2000-05-26 2001-12-06 Washington State University Research Foundation Palmitate desaturase gene
WO2001096363A1 (en) 2000-06-12 2001-12-20 Boyce Thompson Institute For Plant Research Fatty acid desaturase gene and protein for modulating activation of defense signaling pathways in plants
AU7007701A (en) 2000-06-23 2002-01-08 Millennium Pharm Inc 46508, a novel human peptidyl-trna hydrolase family member and uses thereof
AU2001271732A1 (en) 2000-06-29 2002-01-14 Millennium Pharmaceuticals, Inc. 25869, a human carboxylesterase and uses thereof
EP1354049A2 (en) 2000-07-17 2003-10-22 Millenium Pharmaceuticals, Inc. 16816 and 16839, human phospholipase c molecules and uses therefor
GB0316629D0 (en) 2003-07-16 2003-08-20 Univ York Transgenic cell
AU2001286621A1 (en) 2000-08-21 2002-03-04 Millennium Pharmaceuticals, Inc. Human transporter family members and uses thereof
EP1322767B1 (en) 2000-09-26 2008-07-23 Xenon Pharmaceuticals Inc. Methods and compositions employing a stearoyl-coa desaturase-hscd5
DK1911837T3 (da) 2000-09-28 2011-08-29 Bioriginal Food & Science Corp FAD5-2 fedtsyredesaturasefamiliemedlem og anvendelser deraf
JP2004513662A (ja) 2000-11-29 2004-05-13 キセノン ジェネティックス インコーポレイテッド ヒトエロンガーゼ遺伝子、その使用およびそれを調節する化合物
DE10102338A1 (de) 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
DE10102337A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte
US6635451B2 (en) 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
AU2002309482B2 (en) 2001-01-25 2007-08-30 Abbott Laboratories Desaturase genes and uses thereof
DE10106660A1 (de) 2001-02-12 2002-08-29 Celanese Ventures Gmbh Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
WO2002081702A1 (fr) 2001-04-05 2002-10-17 Idemitsu Technofine Co., Ltd. Genes de desaturase en position $g(d)6 d'acide gras, plasmides et transformants contenant ces genes
JP4157382B2 (ja) 2001-04-11 2008-10-01 ローベルト ボツシユ ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 振動減衰式のハンドグリップを備えた手持ち工作機械
TWI426127B (zh) 2001-04-16 2014-02-11 Dsm智慧財產有限公司 多不飽和脂肪酸(pufa)聚乙醯合成酶系統及其用途(三)
TWI377253B (en) 2001-04-16 2012-11-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US20030082754A1 (en) 2001-05-04 2003-05-01 Pradip Mukerji Delta4 - desaturase genes and uses thereof
US7045683B2 (en) 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
EP1392623A4 (en) * 2001-05-14 2005-05-04 Martek Biosciences Corp PREPARATION AND USE OF A POLAR LIPID RICH FRACTION CONTAINING HIGHLY UNSATURATED OMEGA-3 AND / OR OMEGA-6 FATTY ACIDS FROM MICROBES, SEEDS OF GENETICALLY MODIFIED PLANTS AND MARINE ORGANISMS
EP1423521B1 (en) 2001-06-06 2008-08-13 Bioriginal Food & Science Corp. Flax (linum usitatissimum l.) seed-specific sequences
DE10134660A1 (de) 2001-07-20 2003-02-06 Basf Plant Science Gmbh Fettsäure-Desaturase-Gene aus Granatapfel und Verfahren zur Herstellung von ungesättigten Fettsäuren
US20050089879A1 (en) 2001-07-31 2005-04-28 Ivo Feussner Method for producing arachidonic acid in transgenic organisms
US6875595B2 (en) 2001-09-13 2005-04-05 Divergence, Inc. Nematode fatty acid desaturase-like sequences
JP2003116566A (ja) 2001-10-12 2003-04-22 Osamu Suzuki n−3系ドコサペンタエン酸の製造方法
EP1472357B1 (de) 2002-01-30 2009-12-16 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren mittels eines neuen elongase-gens
US7211656B2 (en) 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
US7700833B2 (en) 2002-03-01 2010-04-20 Cornell University Process for the production of unsaturated fatty acids
US7705202B2 (en) 2002-03-16 2010-04-27 The University Of York Transgenic plants expressing enzymes involved in fatty acid biosynthesis
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
MXPA04011613A (es) 2002-05-22 2005-03-07 Monsanto Technology Llc Desaturasas de acido graso de hongos.
AU2003258496A1 (en) 2002-07-03 2004-01-23 Basf Plant Science Gmbh Method for the production of conjugated polyunsaturated fatty acids comprising at least two double bonds in plants
CN1675802A (zh) 2002-08-19 2005-09-28 安德森电工产品公司 用于电连接器的手柄锁定系统及其方法
EP1576166B1 (en) 2002-12-19 2014-10-15 University Of Bristol Novel method for the production of polyunsaturated fatty acids
GB0229578D0 (en) * 2002-12-19 2003-01-22 Univ Bristol Novel method for the production of polyunsaturated fatty acids
US8084074B2 (en) 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
BRPI0407138A (pt) 2003-02-27 2006-01-10 Basf Plant Science Gmbh Sequência de ácido nucleico isolada, sequência de aminoácido, construção de gene, vetor, organismo transgênico não humano, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeo, ou um ácido graxo poliinsaturado ou uma fração dos mesmos, composições de óleo, de lipìdeos, ou de ácido graxo, e, uso do óleo, lipìdeos ou ácidos graxos ou de composições de óleo, de lipìdeos ou de ácido graxo
AU2004225838B2 (en) 2003-03-31 2009-11-05 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
DE10315026A1 (de) 2003-04-02 2004-10-14 Bioplanta Arzneimittel Gmbh Zusammensetzungen enthaltend omega-3-fettsäurehaltige Öle und Pflanzenextrakte
EP1613744B1 (de) 2003-04-08 2015-09-09 BASF Plant Science GmbH Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
WO2004092367A1 (en) 2003-04-16 2004-10-28 Basf Plant Science Gmbh Use of genes for increasing the oil content in plants
US8313911B2 (en) 2003-05-07 2012-11-20 E I Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) * 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7238482B2 (en) 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US20110059496A1 (en) 2003-06-25 2011-03-10 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
US7267976B2 (en) 2003-07-02 2007-09-11 E.I. Du Pont De Nemours And Company Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
NO347177B1 (no) 2003-08-01 2023-06-19 Basf Plant Science Gmbh Fremgangsmåte for fremstilling av flerumettede fettsyrer i transgene organismer
CA2881252C (en) 2003-08-21 2017-02-28 Monsanto Technology Llc Soybean oil having 5 to 50% sda and less than 10% gla
CA2542574C (en) * 2003-11-12 2014-03-18 E. I. Du Pont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
US7504259B2 (en) 2003-11-12 2009-03-17 E. I. Du Pont De Nemours And Company Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
MY140210A (en) 2003-12-22 2009-11-30 Suntory Holdings Ltd Marchantiales-derived unsaturated fatty acid synthetase genes and use of the same
EP1918367B1 (en) 2004-02-17 2011-07-06 The University of York Desaturase Enzymes
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
CA2559360A1 (en) 2004-02-27 2005-09-09 Basf Plant Science Gmbh Method for producing c18, c20 and c22 polyunsaturated fatty acids in transgenic plants
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
US7217956B2 (en) 2004-03-29 2007-05-15 Articulated Technologies, Llc. Light active sheet material
DE102004017369A1 (de) 2004-04-08 2005-11-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Screeningverfahren zur Identifizierung von PUFA-PKS in Proben
DE102004017370A1 (de) 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
EP1734947B1 (en) 2004-04-16 2015-04-15 Monsanto Technology, LLC Expression of fatty acid desaturases in corn
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
CN101018862B (zh) * 2004-04-22 2013-10-09 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
CA3056110C (en) 2004-04-22 2020-07-14 Surinder Pal Singh Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
AU2005235627B2 (en) 2004-04-22 2011-07-07 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
WO2005118814A2 (en) 2004-06-04 2005-12-15 Fluxome Sciences A/S Metabolically engineered cells for the production of polyunsaturated fatty acids
EP1758991B1 (en) 2004-06-25 2013-01-16 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
DE102004060340A1 (de) * 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
US7270315B2 (en) 2004-09-28 2007-09-18 Amt International, Inc. Exchange column, perforated tray assembly
GB0421937D0 (en) 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
US7192762B2 (en) 2004-11-04 2007-03-20 E. I. Du Pont De Nemours And Company Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7273746B2 (en) 2004-11-04 2007-09-25 E.I. Dupont De Nemours And Company Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7189559B2 (en) 2004-11-04 2007-03-13 E. I. Du Pont De Nemours And Company Mortierella alpina lysophosphatidic acid acyltransferase homolog for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US7198937B2 (en) 2004-11-04 2007-04-03 E. I. Du Pont De Nemours And Company Mortierella alpina diacylglycerol acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
US8685679B2 (en) 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
US20060094102A1 (en) 2004-11-04 2006-05-04 Zhixiong Xue Ammonium transporter promoter for gene expression in oleaginous yeast
WO2006064317A1 (en) 2004-12-14 2006-06-22 Avestha Gengraine Technologies Pvt. Ltd. Recombinant production docosahexaenoic acid (dha) in yeast
DE102004062294A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
DE102004063326A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
WO2006135866A2 (en) 2005-06-10 2006-12-21 Martek Biosciences Corporation Pufa polyketide synthase systems and uses thereof
WO2007005882A2 (en) * 2005-07-05 2007-01-11 North Carolina State University Methods and compositions for expressing proteins in plants
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
CA2624661C (en) 2005-11-23 2015-06-30 E.I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US8222488B2 (en) * 2006-02-03 2012-07-17 Texas A&M University System Enhancing expression of value-added genes by transgenic expression of tombusvirus-based P19 gene mutants
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
WO2007106903A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
KR101515044B1 (ko) 2006-05-29 2015-05-19 아이콘 제네틱스 지엠비에이치 식물 바이러스 기반 유도성 발현 시스템
JP4230494B2 (ja) 2006-06-06 2009-02-25 日立建機株式会社 電気駆動ダンプトラックの駆動システム
US8003853B2 (en) * 2006-07-11 2011-08-23 Bioriginal Food & Science Corp. Fatty acid desaturases and uses thereof
DE102006034313A1 (de) 2006-07-21 2008-01-24 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure
CA2659993C (en) 2006-08-24 2016-01-05 Basf Plant Science Gmbh Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
ES2531391T3 (es) * 2006-10-06 2015-03-13 Basf Plant Science Gmbh Delta-5 desaturasas y procedimiento para la preparación de ácidos grasos poliinsaturados en organismos transgénicos no humanos
US8916361B2 (en) 2006-11-17 2014-12-23 Abbott Laboratories Elongase gene and uses thereof
US7709239B2 (en) 2006-12-07 2010-05-04 E.I. Du Pont De Nemours And Company Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids
WO2008104559A1 (de) * 2007-02-27 2008-09-04 Norddeutsche Pflanzenzucht Verfahren zur herstellung von mehrfach ungesättigten fettsäuren in transgenen organismen
BRPI0808577A2 (pt) 2007-04-03 2019-09-24 E.I. Du Pont De Nemours And Company multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeo
US7794701B2 (en) 2007-04-16 2010-09-14 E.I. Du Pont De Nemours And Company Δ-9 elongases and their use in making polyunsaturated fatty acids
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
EP2176433B1 (de) 2007-07-31 2011-10-12 BASF Plant Science GmbH Desaturasen und verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
EP2176416B1 (de) 2007-07-31 2016-03-16 BASF Plant Science GmbH Elongasen und verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen organismen
US8119784B2 (en) 2008-04-02 2012-02-21 E. I. Du Pont De Nemours And Company Delta-4 desaturase and its use in making polyunsaturated fatty acids
EP2271223A2 (de) 2008-04-25 2011-01-12 BASF Plant Science GmbH Pflanzensamenöl
WO2009129582A1 (en) 2008-04-25 2009-10-29 Commonwealth Scientific Industrial Research Organisation Polypeptides and methods for producing triacylglycerols comprising modified fatty acids
CN102066564B (zh) 2008-04-30 2015-02-11 罗特哈姆斯泰德研究有限公司 去饱和酶和在转基因生物中产生多不饱和脂肪酸的方法
US8901374B2 (en) 2008-06-03 2014-12-02 Basf Plant Science Gmbh Fatty acid dehydratases and uses thereof
US8168858B2 (en) 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
CA2729496C (en) 2008-07-01 2018-02-13 Basf Plant Science Gmbh Promoters from brassica napus for seed specific gene expression
WO2010009500A1 (en) 2008-07-21 2010-01-28 Commonwealth Scientific And Industrial Research Organisation Improved vegetable oils and uses therefor
CN102202498B (zh) 2008-07-21 2016-09-07 澳大利亚联邦科学与工业研究组织 改良的棉籽油及应用
EP2331695B1 (en) 2008-08-26 2014-07-23 BASF Plant Science GmbH Nucleic acids encoding desaturases and modified plant oil
CA2737595C (en) 2008-10-14 2017-09-12 Monsanto Technology Llc Utilization of fatty acid desaturases from hemiselmis spp.
DK2358882T3 (da) * 2008-11-18 2017-11-06 Commw Scient Ind Res Org Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer
AU2009326129B2 (en) 2008-12-12 2016-05-12 Basf Plant Science Gmbh Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
CA2760326A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
US8188335B2 (en) 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
CA3161358A1 (en) 2009-07-17 2011-01-20 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
AU2010288482A1 (en) 2009-08-31 2012-04-12 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis
CA2804025C (en) 2010-06-28 2023-02-21 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids
US9311457B1 (en) 2011-11-02 2016-04-12 Google Inc. Platform for cloud application software
US8946460B2 (en) 2012-06-15 2015-02-03 Commonwealth Scientific And Industrial Research Organisation Process for producing polyunsaturated fatty acids in an esterified form
KR102386838B1 (ko) 2013-12-18 2022-04-15 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 장쇄 다중불포화 지방산을 포함하는 지질
WO2015196250A1 (en) 2014-06-27 2015-12-30 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid

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