CA3031170A1 - Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer - Google Patents

Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer Download PDF

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Publication number
CA3031170A1
CA3031170A1 CA3031170A CA3031170A CA3031170A1 CA 3031170 A1 CA3031170 A1 CA 3031170A1 CA 3031170 A CA3031170 A CA 3031170A CA 3031170 A CA3031170 A CA 3031170A CA 3031170 A1 CA3031170 A1 CA 3031170A1
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Prior art keywords
complex
seq
peptide
epitopes
amino acid
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Pending
Application number
CA3031170A
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English (en)
French (fr)
Inventor
Madiha DEROUAZI
Elodie BELNOUE
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Amal Therapeutics SA
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Amal Therapeutics SA
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Publication of CA3031170A1 publication Critical patent/CA3031170A1/en
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/0005Vertebrate antigens
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    • A61K39/00119Melanoma antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/34Antigenic peptides
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  • Epidemiology (AREA)
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  • Oncology (AREA)
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  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Developmental Biology & Embryology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Genetics & Genomics (AREA)
CA3031170A 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer Pending CA3031170A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2016/072475 2016-09-21
EP2016072475 2016-09-21
PCT/EP2017/073954 WO2018055060A1 (en) 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer

Publications (1)

Publication Number Publication Date
CA3031170A1 true CA3031170A1 (en) 2018-03-29

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ID=60037562

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3031170A Pending CA3031170A1 (en) 2016-09-21 2017-09-21 Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer

Country Status (15)

Country Link
US (3) US20190255165A1 (enExample)
EP (1) EP3515476B1 (enExample)
JP (1) JP7346291B2 (enExample)
KR (2) KR20190057345A (enExample)
CN (1) CN109963585B (enExample)
AU (1) AU2017331949B2 (enExample)
CA (1) CA3031170A1 (enExample)
CL (3) CL2019000694A1 (enExample)
DK (1) DK3515476T3 (enExample)
ES (1) ES2983085T3 (enExample)
HU (1) HUE067838T2 (enExample)
IL (1) IL265479B (enExample)
MX (1) MX2019002968A (enExample)
PL (1) PL3515476T3 (enExample)
WO (1) WO2018055060A1 (enExample)

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US20180133327A1 (en) 2015-03-16 2018-05-17 Amal Therapeutics Sa Cell Penetrating Peptides and Complexes Comprising the Same
RU2769314C1 (ru) 2016-03-16 2022-03-30 Амаль Терапьютикс Са Комбинация модулятора иммунных контрольных точек и комплекса, содержащего проникающий в клетку пептид, карго-молекулу и пептидный агонист tlr, для применения в медицине
HUE067838T2 (hu) * 2016-09-21 2024-11-28 Amal Therapeutics Sa Egy sejtpenetráló peptidet, egy multiepitópot és egy TLR peptidagonistát tartalmazó fúzió rák kezelésére
BR112019020853A2 (pt) 2017-04-04 2020-05-12 Avidea Technologies, Inc. Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune
US12121573B2 (en) 2019-07-14 2024-10-22 Tianxin Wang Methods and agents including STING agonist to treat tumor
US11945850B2 (en) 2018-09-17 2024-04-02 Immatics Biotechnologies Gmbh B*44 restricted peptides for use in immunotherapy against cancers and related methods
CA3141084A1 (en) * 2019-06-12 2020-12-17 Vikram JUNEJA Neoantigen compositions and uses thereof
CN110448689A (zh) * 2019-08-06 2019-11-15 太仓美诺恒康生物技术有限公司 mRNA疫苗及其试剂盒、应用
WO2021102215A1 (en) * 2019-11-22 2021-05-27 The University Of North Carolina At Chapel Hill Methods and compositions for increasing transduction efficiency with cell membrane fusion proteins
EP3827840A1 (en) * 2019-11-29 2021-06-02 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Teipp peptide variant and uses thereof
WO2021236658A1 (en) 2020-05-19 2021-11-25 Boehringer Ingelheim International Gmbh Binding molecules for the treatment of cancer
MX2023002884A (es) * 2020-09-14 2023-03-31 Boehringer Ingelheim Int Vacuna heterologa de estimulo primario.
WO2022079175A1 (en) * 2020-10-14 2022-04-21 Boehringer Ingelheim International Gmbh Combination of a sting agonist and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist
CN113480666B (zh) * 2021-08-13 2024-01-26 郑州伊美诺生物技术有限公司 Ca153融合蛋白及其制备方法和ca153检测质控品或校准品
CN113786481A (zh) * 2021-09-27 2021-12-14 深圳市中佳生物医疗科技有限公司 一种抗肿瘤疫苗及其制备方法
MX2024011238A (es) * 2022-03-16 2024-09-19 Boehringer Ingelheim Int Antigenos tumorales, compuestos que comprenden los antigenos tumorales kras, tpx2 o aurka y usos de los mismos.
KR102823824B1 (ko) 2022-08-10 2025-06-24 강원대학교산학협력단 Pde5 억제제 특이적 결합 도메인, 재조합 단백질 및 이의 용도
KR102886457B1 (ko) 2022-10-14 2025-11-18 강원대학교산학협력단 mTOR 억제제 특이적 결합 도메인, 재조합 단백질 및 이의 용도
GB202216453D0 (en) * 2022-11-04 2022-12-21 Lisziewicz Julianna Identification of antigens which induce t-cell responses
WO2024196664A1 (en) * 2023-03-17 2024-09-26 University Of Washington Dna vaccine targeting overexpressed antigens in colorectal cancer
JP7723457B2 (ja) * 2023-07-03 2025-08-14 メスキュージェナシス株式会社 細胞膜透過性を有するペプチドおよびそのスクリーニング方法

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