CA3022722A1 - Pi3k protein kinase modulators - Google Patents

Pi3k protein kinase modulators Download PDF

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Publication number
CA3022722A1
CA3022722A1 CA3022722A CA3022722A CA3022722A1 CA 3022722 A1 CA3022722 A1 CA 3022722A1 CA 3022722 A CA3022722 A CA 3022722A CA 3022722 A CA3022722 A CA 3022722A CA 3022722 A1 CA3022722 A1 CA 3022722A1
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Canada
Prior art keywords
chromen
substituted
amino
fluorophenyl
unsubstituted
Prior art date
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Abandoned
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CA3022722A
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English (en)
French (fr)
Inventor
Meyyappan Muthuppalaniappan
Srikant Viswanadha
Govindarajulu Babu
Swaroop Kumar VAKKALANKA
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Rhizen Pharmaceuticals AG
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Rhizen Pharmaceuticals AG
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Publication of CA3022722A1 publication Critical patent/CA3022722A1/en
Abandoned legal-status Critical Current

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    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
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    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
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