CA3022673A1 - Tau immunotherapy - Google Patents
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- CA3022673A1 CA3022673A1 CA3022673A CA3022673A CA3022673A1 CA 3022673 A1 CA3022673 A1 CA 3022673A1 CA 3022673 A CA3022673 A CA 3022673A CA 3022673 A CA3022673 A CA 3022673A CA 3022673 A1 CA3022673 A1 CA 3022673A1
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/567—Framework region [FR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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US201662330786P | 2016-05-02 | 2016-05-02 | |
US62/330,786 | 2016-05-02 | ||
PCT/IB2017/052543 WO2017191559A1 (en) | 2016-05-02 | 2017-05-02 | Tau immunotherapy |
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CA3022673A1 true CA3022673A1 (en) | 2017-11-09 |
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CA3022673A Pending CA3022673A1 (en) | 2016-05-02 | 2017-05-02 | Tau immunotherapy |
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US (3) | US10752679B2 (zh) |
EP (1) | EP3452507B1 (zh) |
JP (2) | JP7170316B2 (zh) |
KR (1) | KR102506091B1 (zh) |
CN (1) | CN109415432B (zh) |
CA (1) | CA3022673A1 (zh) |
DK (1) | DK3452507T3 (zh) |
ES (1) | ES2933491T3 (zh) |
FI (1) | FI3452507T3 (zh) |
HU (1) | HUE060258T2 (zh) |
PL (1) | PL3452507T3 (zh) |
PT (1) | PT3452507T (zh) |
WO (1) | WO2017191559A1 (zh) |
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WO2014165271A2 (en) | 2013-03-13 | 2014-10-09 | Neotope Biosciences Limited | Tau immunotherapy |
WO2017191560A1 (en) | 2016-05-02 | 2017-11-09 | Prothena Biosciences Limited | Antibodies recognizing tau |
JP7170316B2 (ja) * | 2016-05-02 | 2022-11-14 | プロセナ バイオサイエンシーズ リミテッド | タウ免疫療法 |
MY197413A (en) | 2016-05-02 | 2023-06-16 | Prothena Biosciences Ltd | Antibodies recognizing tau |
MA47499A (fr) | 2017-02-17 | 2019-12-25 | Denali Therapeutics Inc | Anticorps anti-tau et leurs procédés d'utilisation |
WO2018204546A2 (en) | 2017-05-02 | 2018-11-08 | Prothena Biosciences Limited | Antibodies recognizing tau |
BR112021016947A2 (pt) | 2019-03-03 | 2021-11-03 | Prothena Biosciences Ltd | Anticorpos que reconhecem tau |
EP3966227A1 (en) | 2019-05-07 | 2022-03-16 | Voyager Therapeutics, Inc. | Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation |
KR20220034733A (ko) * | 2019-05-27 | 2022-03-18 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 타우의 입체형태-특이적 에피토프, 이에 대한 항체 및 이와 관련된 방법 |
TW202208409A (zh) | 2020-05-19 | 2022-03-01 | 愛爾蘭商歐薩爾普羅席納有限公司 | 用於治療阿茲海默症之多抗原決定基疫苗 |
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KR102506091B1 (ko) | 2023-03-07 |
JP2022116136A (ja) | 2022-08-09 |
CN109415432B (zh) | 2022-07-08 |
HUE060258T2 (hu) | 2023-02-28 |
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