CA2975452C - Pressure-sensitive adhesives for transdermal drug delivery - Google Patents

Pressure-sensitive adhesives for transdermal drug delivery Download PDF

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Publication number
CA2975452C
CA2975452C CA2975452A CA2975452A CA2975452C CA 2975452 C CA2975452 C CA 2975452C CA 2975452 A CA2975452 A CA 2975452A CA 2975452 A CA2975452 A CA 2975452A CA 2975452 C CA2975452 C CA 2975452C
Authority
CA
Canada
Prior art keywords
monomers
skin
psa
drug delivery
mimicking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2975452A
Other languages
English (en)
French (fr)
Other versions
CA2975452A1 (en
Inventor
Jilin Zhang
Jun Liao
Puchun Liu
Steven Dinh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noven Pharmaceuticals Inc
Original Assignee
Noven Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharmaceuticals Inc filed Critical Noven Pharmaceuticals Inc
Publication of CA2975452A1 publication Critical patent/CA2975452A1/en
Application granted granted Critical
Publication of CA2975452C publication Critical patent/CA2975452C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/24—Homopolymers or copolymers of amides or imides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Adhesive Tapes (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Laminated Bodies (AREA)
CA2975452A 2015-02-06 2016-02-05 Pressure-sensitive adhesives for transdermal drug delivery Active CA2975452C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562112982P 2015-02-06 2015-02-06
US62/112,982 2015-02-06
PCT/US2016/016696 WO2016127020A1 (en) 2015-02-06 2016-02-05 Pressure-sensitive adhesives for transdermal drug delivery

Publications (2)

Publication Number Publication Date
CA2975452A1 CA2975452A1 (en) 2016-08-11
CA2975452C true CA2975452C (en) 2024-03-12

Family

ID=55436165

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2975452A Active CA2975452C (en) 2015-02-06 2016-02-05 Pressure-sensitive adhesives for transdermal drug delivery

Country Status (13)

Country Link
US (1) US10406115B2 (https=)
EP (1) EP3253840B1 (https=)
JP (2) JP6807848B2 (https=)
KR (1) KR102565565B1 (https=)
CN (1) CN107532050B (https=)
AU (1) AU2016215180B2 (https=)
CA (1) CA2975452C (https=)
ES (1) ES2748352T3 (https=)
HK (1) HK1248265B (https=)
MX (1) MX371044B (https=)
PH (1) PH12017501371B1 (https=)
TW (1) TWI689321B (https=)
WO (1) WO2016127020A1 (https=)

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EP3253840B1 (en) 2015-02-06 2019-07-31 Noven Pharmaceuticals, INC. Pressure-sensitive adhesives for transdermal drug delivery
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
EP3506889A1 (en) * 2016-08-03 2019-07-10 Noven Pharmaceuticals, INC. Pressure-sensitive adhesives for transdermal drug delivery
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
JP2019183078A (ja) * 2018-04-17 2019-10-24 日立化成株式会社 粘着剤
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
CN114207073B (zh) * 2019-07-30 2023-12-05 日东电工株式会社 粘合剂组合物、粘合剂层及粘合片
JP7802011B2 (ja) * 2020-05-04 2026-01-19 ビーブイダブリュ インベスト エージー 膨潤を介して対象表面に接着する接着装置
CA3203042A1 (en) 2021-01-07 2022-07-14 Deboprosad MONDAL Amphetamine carbamate compounds and methods
TW202241397A (zh) 2021-01-07 2022-11-01 美商諾芬藥品公司 含低量胺基甲酸鹽之經皮安非他命組合物
CN116139287A (zh) * 2023-02-23 2023-05-23 杭州创剂医药科技有限公司 含羟苯基聚丙烯酸酯的压敏胶基质及其制备方法
US12514756B1 (en) 2024-10-08 2026-01-06 Covidien Lp Dermal patch and systems, kits, and methods associated therewith

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Also Published As

Publication number Publication date
KR102565565B1 (ko) 2023-08-09
HK1248265B (en) 2020-04-03
WO2016127020A1 (en) 2016-08-11
CA2975452A1 (en) 2016-08-11
EP3253840A1 (en) 2017-12-13
JP2018510926A (ja) 2018-04-19
CN107532050A (zh) 2018-01-02
TWI689321B (zh) 2020-04-01
PH12017501371B1 (en) 2022-10-26
US10406115B2 (en) 2019-09-10
US20160228383A1 (en) 2016-08-11
AU2016215180B2 (en) 2020-01-02
AU2016215180A1 (en) 2017-08-17
JP2021073324A (ja) 2021-05-13
MX371044B (es) 2020-01-13
PH12017501371A1 (en) 2017-12-18
CN107532050B (zh) 2021-03-02
ES2748352T3 (es) 2020-03-16
JP6807848B2 (ja) 2021-01-06
MX2017010000A (es) 2018-02-19
KR20170113636A (ko) 2017-10-12
EP3253840B1 (en) 2019-07-31
TW201634064A (zh) 2016-10-01

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