CA2942776C - Polyneucleotide cassette and expression vector for expression of a gene in cone cells using truncated m-opsin promoter - Google Patents
Polyneucleotide cassette and expression vector for expression of a gene in cone cells using truncated m-opsin promoter Download PDFInfo
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- CA2942776C CA2942776C CA2942776A CA2942776A CA2942776C CA 2942776 C CA2942776 C CA 2942776C CA 2942776 A CA2942776 A CA 2942776A CA 2942776 A CA2942776 A CA 2942776A CA 2942776 C CA2942776 C CA 2942776C
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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Landscapes
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (5)
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| US201461954330P | 2014-03-17 | 2014-03-17 | |
| US61/954,330 | 2014-03-17 | ||
| US201562127185P | 2015-03-02 | 2015-03-02 | |
| US62/127,185 | 2015-03-02 | ||
| PCT/US2015/021087 WO2015142941A1 (en) | 2014-03-17 | 2015-03-17 | Compositions and methods for enhanced gene expression in cone cells |
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| CA2942776A1 CA2942776A1 (en) | 2015-09-24 |
| CA2942776C true CA2942776C (en) | 2023-01-24 |
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| CA2942776A Active CA2942776C (en) | 2014-03-17 | 2015-03-17 | Polyneucleotide cassette and expression vector for expression of a gene in cone cells using truncated m-opsin promoter |
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| US (3) | US10000741B2 (OSRAM) |
| EP (2) | EP3119798B1 (OSRAM) |
| JP (4) | JP6689249B2 (OSRAM) |
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| CN (2) | CN106414474B (OSRAM) |
| AU (3) | AU2015231439B2 (OSRAM) |
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| ES (2) | ES3042252T3 (OSRAM) |
| IL (2) | IL259321B2 (OSRAM) |
| SG (2) | SG10201810150UA (OSRAM) |
| WO (1) | WO2015142941A1 (OSRAM) |
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| US20120172419A1 (en) | 2009-09-15 | 2012-07-05 | Medical College Of Wisconsin Research Foundation Inc. | Reagents and methods for modulating cone photoreceptor activity |
| SMT202400520T1 (it) | 2011-04-22 | 2025-01-14 | Univ California | Virioni di virus adeno-associato con capside variante e relativi metodi di utilizzo |
| TWI698240B (zh) | 2012-05-15 | 2020-07-11 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| CN105247044B (zh) | 2013-05-31 | 2021-05-07 | 加利福尼亚大学董事会 | 腺相关病毒变体及其使用方法 |
| CN106414474B (zh) | 2014-03-17 | 2021-01-15 | 阿德夫拉姆生物技术股份有限公司 | 用于视锥细胞中增强的基因表达的组合物和方法 |
| CA2978068C (en) * | 2015-03-02 | 2024-05-28 | Adverum Biotechnologies, Inc. | Compositions and methods for intravitreal delivery of polynucleotides to retinal cones |
| ES2900486T3 (es) * | 2015-12-03 | 2022-03-17 | Friedrich Miescher Institute For Biomedical Res | SynP160, un promotor para la expresión específica de genes en los fotorreceptores de los bastones |
| CA3006952A1 (en) | 2015-12-03 | 2017-06-08 | Friedrich Miescher Institute For Biomedical Research | Synp161, a promoter for the specific expression of genes in rod photoreceptors |
| MX2018007230A (es) | 2015-12-14 | 2018-11-09 | Univ Pennsylvania | Terapia genica para trastornos oculares. |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
| CN107287239B (zh) * | 2016-04-11 | 2020-09-22 | 厦门继景生物技术有限责任公司 | 一种用于视网膜色素变性的基因治疗载体及药物 |
| CA3022600A1 (en) * | 2016-04-29 | 2017-11-02 | Adverum Biotechnologies, Inc. | Evasion of neutralizing antibodies by a recombinant adeno-associated virus |
| WO2017205739A1 (en) | 2016-05-26 | 2017-11-30 | University Of Iowa Research Foundation | cis AND trans REQUIREMENTS FOR TERMINAL RESOLUTION OF HUMAN BOCAVIRUS 1 |
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