CA2909270A1 - Highly active nucleoside derivative for the treatment of hcv - Google Patents
Highly active nucleoside derivative for the treatment of hcvInfo
- Publication number
- CA2909270A1 CA2909270A1 CA2909270A CA2909270A CA2909270A1 CA 2909270 A1 CA2909270 A1 CA 2909270A1 CA 2909270 A CA2909270 A CA 2909270A CA 2909270 A CA2909270 A CA 2909270A CA 2909270 A1 CA2909270 A1 CA 2909270A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- compound
- nucleoside
- salt
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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| US201361811464P | 2013-04-12 | 2013-04-12 | |
| US61/811,464 | 2013-04-12 | ||
| PCT/US2014/034018 WO2014169278A1 (en) | 2013-04-12 | 2014-04-14 | Highly active nucleoside derivative for the treatment of hcv |
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| CA2909270A1 true CA2909270A1 (en) | 2014-10-16 |
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| CA2909273A Abandoned CA2909273A1 (en) | 2013-04-12 | 2014-04-14 | Deuterated nucleoside prodrugs useful for treating hcv |
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| DK2480559T3 (da) | 2009-09-21 | 2013-08-05 | Gilead Sciences Inc | Fremgangsmåder og mellemprodukter til fremstillingen af 1'-cyano-carbanukleosid-analoger |
| MA34470B1 (fr) | 2010-07-22 | 2013-08-01 | Gilead Sciences Inc | Procédés et composés pour traiter des infections à virus paramyxoviridae |
| PL2861611T3 (pl) | 2012-05-25 | 2017-08-31 | Janssen Sciences Ireland Uc | Nukleozydy uracylowe spirooksetanu |
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-
2014
- 2014-04-14 CA CA2909270A patent/CA2909270A1/en not_active Abandoned
- 2014-04-14 BR BR112015025766A patent/BR112015025766A2/pt not_active Application Discontinuation
- 2014-04-14 JP JP2016507703A patent/JP2016522172A/ja active Pending
- 2014-04-14 WO PCT/US2014/034021 patent/WO2014169280A2/en not_active Ceased
- 2014-04-14 KR KR1020157032200A patent/KR20160003700A/ko not_active Withdrawn
- 2014-04-14 BR BR112015025716A patent/BR112015025716A2/pt not_active IP Right Cessation
- 2014-04-14 AU AU2014250762A patent/AU2014250762A1/en not_active Abandoned
- 2014-04-14 CA CA2909273A patent/CA2909273A1/en not_active Abandoned
- 2014-04-14 KR KR1020157032206A patent/KR20160002896A/ko not_active Withdrawn
- 2014-04-14 US US14/252,290 patent/US9447132B2/en not_active Expired - Fee Related
- 2014-04-14 WO PCT/US2014/034018 patent/WO2014169278A1/en not_active Ceased
- 2014-04-14 RU RU2015148006A patent/RU2015148006A/ru not_active Application Discontinuation
- 2014-04-14 CN CN201480033503.7A patent/CN105377868A/zh active Pending
- 2014-04-14 CN CN201480033500.3A patent/CN105705511A/zh active Pending
- 2014-04-14 ES ES14722955.3T patent/ES2623287T3/es active Active
- 2014-04-14 RU RU2015148010A patent/RU2015148010A/ru not_active Application Discontinuation
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- 2014-04-14 AU AU2014250764A patent/AU2014250764A1/en not_active Abandoned
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- 2014-04-14 EP EP14724944.5A patent/EP2984098A2/en not_active Withdrawn
Also Published As
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| CA2909273A1 (en) | 2014-10-16 |
| EP2984097B1 (en) | 2017-03-29 |
| AU2014250764A1 (en) | 2015-10-29 |
| EP2984098A2 (en) | 2016-02-17 |
| US9447132B2 (en) | 2016-09-20 |
| KR20160002896A (ko) | 2016-01-08 |
| RU2015148010A3 (enExample) | 2018-04-28 |
| BR112015025716A2 (pt) | 2017-07-18 |
| ES2623287T3 (es) | 2017-07-10 |
| AU2014250762A1 (en) | 2015-10-29 |
| RU2015148006A (ru) | 2017-05-18 |
| KR20160003700A (ko) | 2016-01-11 |
| RU2015148006A3 (enExample) | 2018-08-01 |
| EP2984097A1 (en) | 2016-02-17 |
| WO2014169280A2 (en) | 2014-10-16 |
| WO2014169278A1 (en) | 2014-10-16 |
| RU2015148010A (ru) | 2017-05-15 |
| JP2016518359A (ja) | 2016-06-23 |
| CN105705511A (zh) | 2016-06-22 |
| CN105377868A (zh) | 2016-03-02 |
| US20140309189A1 (en) | 2014-10-16 |
| BR112015025766A2 (pt) | 2017-10-17 |
| WO2014169280A3 (en) | 2014-12-18 |
| JP2016522172A (ja) | 2016-07-28 |
| US20140309164A1 (en) | 2014-10-16 |
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