CA2882088C - Compounds for the treatment of paramoxyvirus viral infections - Google Patents

Compounds for the treatment of paramoxyvirus viral infections Download PDF

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Publication number
CA2882088C
CA2882088C CA2882088A CA2882088A CA2882088C CA 2882088 C CA2882088 C CA 2882088C CA 2882088 A CA2882088 A CA 2882088A CA 2882088 A CA2882088 A CA 2882088A CA 2882088 C CA2882088 C CA 2882088C
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optionally substituted
compound
pharmaceutically acceptable
acceptable salt
alkyl
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CA2882088A
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French (fr)
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CA2882088A1 (en
Inventor
Guangyi Wang
Leonid Beigelman
Anh Truong
Carmela NAPOLITANO
Daniele Andreotti
Haiying He
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Janssen Biopharma Inc
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Janssen Biopharma Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
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    • A61K31/16—Amides, e.g. hydroxamic acids
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
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ES2779748T3 (es) 2020-08-19
WO2014031784A1 (en) 2014-02-27
AU2013305759A2 (en) 2015-03-26
CA2882088A1 (en) 2014-02-27
PH12015500355B1 (en) 2015-04-20
AU2013305759A1 (en) 2015-03-26
JP2015531769A (ja) 2015-11-05
AU2013305759C1 (en) 2018-01-18
PH12015500355A1 (en) 2015-04-20
MX2015002231A (es) 2015-07-17
CN104736530A (zh) 2015-06-24
AU2013305759B2 (en) 2017-09-28
US20170283429A1 (en) 2017-10-05
ZA201501018B (en) 2019-07-31
US20220396581A1 (en) 2022-12-15
JP6243908B2 (ja) 2017-12-06
US11014935B2 (en) 2021-05-25
EP2888240B1 (en) 2020-01-15
BR112015003376A2 (pt) 2017-07-04
BR112015003376A8 (pt) 2018-01-23
NZ704666A (en) 2018-05-25
IL237275A0 (en) 2015-04-30
EP2888240A4 (en) 2016-04-27
SG11201501036RA (en) 2015-03-30
EP2888240A1 (en) 2015-07-01
HK1211589A1 (en) 2016-05-27

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