CA2878587A1 - Immunoglobulin constructs comprising selective pairing of the light and heavy chains - Google Patents
Immunoglobulin constructs comprising selective pairing of the light and heavy chains Download PDFInfo
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- CA2878587A1 CA2878587A1 CA2878587A CA2878587A CA2878587A1 CA 2878587 A1 CA2878587 A1 CA 2878587A1 CA 2878587 A CA2878587 A CA 2878587A CA 2878587 A CA2878587 A CA 2878587A CA 2878587 A1 CA2878587 A1 CA 2878587A1
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- polypeptide
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- immunoglobulin construct
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Landscapes
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| US201261674820P | 2012-07-23 | 2012-07-23 | |
| US61/674,820 | 2012-07-23 | ||
| US201361857652P | 2013-07-23 | 2013-07-23 | |
| PCT/US2013/051747 WO2014018572A2 (en) | 2012-07-23 | 2013-07-23 | Immunoglobulin constructs comprising selective pairing of the light and heavy chains |
| US61/857,652 | 2013-07-23 |
Publications (1)
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| CA2878587A1 true CA2878587A1 (en) | 2014-01-30 |
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| CA2878587A Abandoned CA2878587A1 (en) | 2012-07-23 | 2013-07-23 | Immunoglobulin constructs comprising selective pairing of the light and heavy chains |
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| US (1) | US20140072581A1 (enExample) |
| JP (1) | JP2015531751A (enExample) |
| CN (1) | CN104640561A (enExample) |
| AU (1) | AU2013293092A1 (enExample) |
| CA (1) | CA2878587A1 (enExample) |
| IN (1) | IN2015DN01299A (enExample) |
| WO (1) | WO2014018572A2 (enExample) |
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| US9023352B2 (en) | 2007-02-20 | 2015-05-05 | Tufts University | Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein |
| WO2011028952A1 (en) | 2009-09-02 | 2011-03-10 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| CN105585630B (zh) | 2010-07-29 | 2020-09-15 | Xencor公司 | 具有修改的等电点的抗体 |
| PL2635607T3 (pl) | 2010-11-05 | 2020-05-18 | Zymeworks Inc. | Projekt stabilnego przeciwciała heterodimerowego z mutacjami w domenie FC |
| AU2012222833B2 (en) | 2011-03-03 | 2017-03-16 | Zymeworks Inc. | Multivalent heteromultimer scaffold design and constructs |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| US10851178B2 (en) | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| HRP20211773T1 (hr) | 2011-11-04 | 2022-03-04 | Zymeworks Inc. | Stabilna heterodimerni dizajn antitijela s mutacijama u fc domeni |
| WO2014004586A1 (en) | 2012-06-25 | 2014-01-03 | Zymeworks Inc. | Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells |
| CN104768571B (zh) | 2012-07-13 | 2018-11-09 | 酵活有限公司 | 多价异多聚体支架设计和构建体 |
| CA2889951C (en) * | 2012-11-02 | 2023-04-18 | Zymeworks Inc. | Crystal structures of heterodimeric fc domains |
| US9914785B2 (en) | 2012-11-28 | 2018-03-13 | Zymeworks Inc. | Engineered immunoglobulin heavy chain-light chain pairs and uses thereof |
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- 2013-07-23 AU AU2013293092A patent/AU2013293092A1/en not_active Abandoned
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| WO2014018572A3 (en) | 2014-03-27 |
| CN104640561A (zh) | 2015-05-20 |
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