CA2873457A1 - Clinical diagnostic system including instrument and cartridge - Google Patents

Clinical diagnostic system including instrument and cartridge Download PDF

Info

Publication number
CA2873457A1
CA2873457A1 CA2873457A CA2873457A CA2873457A1 CA 2873457 A1 CA2873457 A1 CA 2873457A1 CA 2873457 A CA2873457 A CA 2873457A CA 2873457 A CA2873457 A CA 2873457A CA 2873457 A1 CA2873457 A1 CA 2873457A1
Authority
CA
Canada
Prior art keywords
cartridge
sample
fluidic
diagnostic
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2873457A
Other languages
English (en)
French (fr)
Inventor
Richard Alan COOK
Sang Cho
Charles Quentin Davis
Kevin E. DORSEY
Jason Charles Harley
Jonathan Leland
Rober Krikor Matikyan
Sjef Otten
Jeffrey Howard PETERMAN
Brian B. THOMAS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Defined Diagnostics LLC
Original Assignee
Wellstat Diagnostics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/067041 external-priority patent/WO2013082273A1/en
Application filed by Wellstat Diagnostics LLC filed Critical Wellstat Diagnostics LLC
Publication of CA2873457A1 publication Critical patent/CA2873457A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/06—Control using electricity
    • F04B49/065—Control using electricity and making use of computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/04—Packaging single articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/10—Other safety measures
    • F04B49/106—Responsive to pumped volume
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B1/00—Details of electric heating devices
    • H05B1/02—Automatic switching arrangements specially adapted to apparatus ; Control of heating devices
    • H05B1/0227—Applications
    • H05B1/023—Industrial applications
    • H05B1/025—For medical applications
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/10—Means to control humidity and/or other gases
    • B01L2300/105—Means to control humidity and/or other gases using desiccants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Computer Hardware Design (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Plasma & Fusion (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2873457A 2012-05-15 2013-05-15 Clinical diagnostic system including instrument and cartridge Abandoned CA2873457A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261647272P 2012-05-15 2012-05-15
US61/647,272 2012-05-15
PCT/US2012/067041 WO2013082273A1 (en) 2011-11-30 2012-11-29 Filtration module
USPCT/US2012/067041 2012-11-29
US13/844,527 2013-03-15
US13/844,527 US9075042B2 (en) 2012-05-15 2013-03-15 Diagnostic systems and cartridges
US13/844,450 2013-03-15
US13/844,450 US9081001B2 (en) 2012-05-15 2013-03-15 Diagnostic systems and instruments
PCT/US2013/041252 WO2013173524A2 (en) 2012-05-15 2013-05-15 Clinical diagnostic system including instrument and cartridge

Publications (1)

Publication Number Publication Date
CA2873457A1 true CA2873457A1 (en) 2013-11-21

Family

ID=49621757

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2873457A Abandoned CA2873457A1 (en) 2012-05-15 2013-05-15 Clinical diagnostic system including instrument and cartridge
CA2873459A Abandoned CA2873459A1 (en) 2012-05-15 2013-05-15 Clinical diagnostic systems

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2873459A Abandoned CA2873459A1 (en) 2012-05-15 2013-05-15 Clinical diagnostic systems

Country Status (7)

Country Link
US (3) US9075042B2 (enExample)
EP (2) EP2852834A4 (enExample)
JP (2) JP2015516583A (enExample)
CN (2) CN104427929A (enExample)
AU (2) AU2013262815B2 (enExample)
CA (2) CA2873457A1 (enExample)
WO (2) WO2013173524A2 (enExample)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
EP2527814A1 (en) * 2011-04-27 2012-11-28 Koninklijke Philips Electronics N.V. Sensor system with an exchangeable cartridge and a reader
CN107277956B (zh) 2011-12-28 2021-02-05 雅培制药有限公司 利用感应加热来减少生物携带的方法和设备
CN104411406B (zh) * 2012-03-16 2017-05-31 统计诊断与创新有限公司 具有集成传送模块的测试盒
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9675973B2 (en) * 2012-06-14 2017-06-13 Paratus Diagnostics, LLC Specimen delivery apparatus
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
KR101439790B1 (ko) * 2013-09-12 2014-09-12 유승국 진단 키트 제조 장치 및 이에 의해 제조된 진단 키트
EP3077076A4 (en) * 2013-12-04 2017-09-20 Pocared Diagnostics Ltd Filter arrangement with slider valve and method for using the same
FI125449B (en) * 2013-12-18 2015-10-15 Thermo Fisher Scientific Oy Electronic pipette
NL2012023C2 (en) * 2013-12-24 2015-06-26 Micronit Microfluidics Bv Device and method for measuring a volume of a liquid and method and device for calibrating a liquid dispensing system.
US9827567B2 (en) * 2014-04-22 2017-11-28 Nanosphere, Inc. Diagnostic cartridges having flexible seals
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
WO2016089477A1 (en) * 2014-10-16 2016-06-09 Cepheid Biosecurity screening system and method
JP6927879B2 (ja) * 2015-01-14 2021-09-01 ピクセル メディカル テクノロジーズ リミテッド 試料流体分析用の使い捨てカートリッジ
US10088398B2 (en) 2015-02-11 2018-10-02 Emd Millipore Corporation Stirred cell and method of using same
US9901668B2 (en) 2015-03-17 2018-02-27 Fenwal, Inc. Indicating to a medical device performance of an operation by another medical device
CA2984345C (en) * 2015-04-30 2019-11-12 Vpi Engineering, Inc. Method and system for calibrating gamma radiation flux levels in a solid state gamma radiation detection system
EP3088887B1 (de) * 2015-05-01 2017-08-16 CTC Analytics AG Vorrichtung zur extraktion flüchtiger komponenten
USD804653S1 (en) 2015-06-12 2017-12-05 Emd Millipore Corporation Pressure vessel
CN105092329B (zh) * 2015-07-31 2018-06-26 青岛市妇女儿童医院 医学检验样品辅助处理器
KR101810942B1 (ko) * 2015-09-04 2018-01-25 (주)나노엔텍 샘플 전처리 시스템 및 그 제어방법
ES2912965T3 (es) 2015-09-09 2022-05-30 Drawbridge Health Inc Dispositivos para la recopilación, estabilización y conservación de muestras
WO2017045088A1 (zh) * 2015-09-15 2017-03-23 薛迎风 全自动枸橼酸局部抗凝机
CN108367290B (zh) 2015-10-01 2021-06-04 伯克利之光生命科技公司 井孔板培养器
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
CN107850610B (zh) * 2015-10-16 2021-02-26 深圳迈瑞生物医疗电子股份有限公司 一种样本测试申请方法、装置及样本分析仪
KR102577994B1 (ko) * 2015-11-03 2023-09-13 프리시젼바이오 주식회사 유체 시료 검사기기
SG11201803655SA (en) * 2015-11-04 2018-05-30 Nitto Denko Corp Apparatus and system for biofluid sample dispensing and/or assay
WO2017096284A1 (en) * 2015-12-03 2017-06-08 Ca Casyso Ag Blood testing system and method
US9682378B1 (en) 2015-12-08 2017-06-20 Paratus Diagnostics, LLC Mating adaptor for coupling a point-of-care diagnostic cartridge to a computing device
US10436781B2 (en) 2016-01-27 2019-10-08 Paratus Diagnostics, LLC Point-of-care diagnostic cartridge having a digital micro-fluidic testing substrate
JP6690655B2 (ja) * 2016-02-02 2020-04-28 コニカミノルタ株式会社 送液方法、ならびにこれを行う検出システムおよび検出装置
WO2017138670A1 (ko) * 2016-02-11 2017-08-17 (주)타스컴 생체 측정 시스템
BR112018072252B1 (pt) * 2016-04-29 2023-04-25 Baebies, Inc Cartucho bioquímico para triagem de recém-nascidos
US11493474B2 (en) * 2016-07-01 2022-11-08 Tubitak Mobile hand-held device with reusable biosensor cartridge
US10072962B2 (en) 2016-07-05 2018-09-11 Ecolab Usa Inc. Liquid out-of-product alarm system and method
WO2018102781A1 (en) * 2016-12-01 2018-06-07 Berkeley Lights, Inc. Well-plate incubator
CN110291843B (zh) 2016-12-22 2022-06-28 雅培制药有限公司 用于减少生物遗留的感应加热系统及其控制方法
CN210383905U (zh) 2017-01-10 2020-04-24 集联健康有限公司 一种用于从受试者收集流体样品的装置以及运输套筒
USD819225S1 (en) * 2017-01-19 2018-05-29 Life Technologies Corporation Capillary electrophoresis instrument
WO2018140485A1 (en) 2017-01-26 2018-08-02 Counsyl, Inc. Reagent delivery and waste management system
US9719892B1 (en) 2017-01-30 2017-08-01 Paratus Diagnostic, Llc Processing device for processing a highly viscous sample
US10508976B1 (en) * 2017-03-31 2019-12-17 Advanced Micro Instruments, Inc. Gas sampling device and method
JP6710850B1 (ja) 2017-04-20 2020-06-17 バイオフルイディカ、インコーポレイテッド 液体サンプルからバイオマーカーを単離するための流体密封性フローシステム
US10677709B2 (en) * 2017-04-28 2020-06-09 Becton, Dickinson And Company Particle detection cartridges, systems thereof and methods for using the same
US11077444B2 (en) * 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
WO2019025224A1 (en) * 2017-08-01 2019-02-07 Roche Diagnostics Gmbh METHOD OF MONITORING ANALYTE DETECTION OPERATION IN A LIQUID SAMPLE
CA3070832A1 (en) 2017-08-02 2019-02-07 Pocared Diagnostics Ltd. Processor filter arrangement that includes method and apparatus to remove waste fluid through a filter
EP3444033B1 (en) 2017-08-18 2020-01-08 CTC Analytics AG Cartridge for chemical or biological assays
CN108281178A (zh) * 2018-02-12 2018-07-13 深圳迎凯生物科技有限公司 体外诊断设备参数更新的方法及装置
JP1613139S (enExample) * 2018-03-13 2021-09-06
JP2019174318A (ja) * 2018-03-29 2019-10-10 株式会社日立ハイテクノロジーズ 分注装置、分注方法
US11541396B2 (en) * 2018-03-30 2023-01-03 Idexx Laboratories, Inc. Point-of-care diagnostic systems and containers for same
USD876961S1 (en) 2018-03-30 2020-03-03 Idexx Laboratories, Inc. Container
USD876960S1 (en) 2018-03-30 2020-03-03 Idexx Laboratories, Inc. Container
US11358148B2 (en) 2018-03-30 2022-06-14 Idexx Laboratories, Inc. Point-of-care diagnostic systems and containers for same
US11007526B2 (en) * 2018-07-06 2021-05-18 Qorvo Us, Inc. Capless sample well port for a cartridge
US11541385B2 (en) * 2018-07-06 2023-01-03 Qorvo Us, Inc. Methods of measuring hematocrit in fluidic channels including conductivity sensor
US11459604B2 (en) 2018-07-12 2022-10-04 Luminex Corporation Systems and methods for performing variable sample preparation and analysis processes
WO2020106556A1 (en) 2018-11-20 2020-05-28 Xatek, Inc. Dielectric spectroscopy sensing apparaus and method of use
CN113474662A (zh) * 2018-12-28 2021-10-01 贝克曼库尔特有限公司 临床分析仪自动化系统诊断
CA3125901A1 (en) * 2019-01-07 2020-07-16 1866402 Ontario Limited Blood separation and analysis device and methods
JP7261617B2 (ja) * 2019-03-04 2023-04-20 株式会社日立ハイテク 自動分析装置
USD975312S1 (en) 2020-02-14 2023-01-10 Beckman Coulter, Inc. Reagent cartridge
CN111449688B (zh) * 2020-04-13 2022-07-08 西安交通大学医学院第一附属医院 一种早期胃肠道肿瘤的诊断仪
EP4164795A4 (en) 2020-06-12 2024-01-24 BioFluidica, Inc. DUAL-DEPTH THERMOPLASTIC MICROFLUIDIC DEVICE AND ASSOCIATED SYSTEMS AND METHODS
DE102020210416A1 (de) * 2020-08-17 2022-02-17 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Aufbereitungsvorrichtung und Verfahren zum Betreiben einer mikrofluidischen Aufbereitungsvorrichtung
GB2600103B (en) * 2020-10-19 2024-01-10 Quantumdx Group Ltd Integrated thermal conditioning and PCR in a molecular POC diagnostic system
CN117120842A (zh) * 2021-04-01 2023-11-24 美国西门子医学诊断股份有限公司 具有分类能力的诊断仪器及其分类方法
US12383906B2 (en) 2021-06-14 2025-08-12 University Of Washington Device and method for detection of pathogens
US11919004B2 (en) * 2021-08-30 2024-03-05 Wisconsin Alumni Research Foundation One-step sample extraction cassette and method for point-of-care molecular testing
CN114994023B (zh) * 2022-05-10 2025-05-16 南京理工大学 一种基于天然染料的电化学发光体系的构建方法及应用
CN115356335A (zh) * 2022-09-05 2022-11-18 广西电网有限责任公司来宾供电局 一种气体检测管自动检测仪
KR102548277B1 (ko) * 2022-11-15 2023-06-29 주식회사 위즈바이오솔루션 분자진단용 카트리지 및 상기 카트리지를 갖는 분자진단장치
WO2024107950A2 (en) * 2022-11-16 2024-05-23 Siemens Healthcare Diagnostics Inc. Devices and methods for transporting samples in diagnostic laboratory systems
KR102758657B1 (ko) * 2022-11-17 2025-01-22 엔트온(주) 유체분석기
AT526065B1 (de) * 2022-12-20 2023-11-15 Georg Hagleitner Hans Verfahren zum Kalibrieren eines Fördergeräts, Verfahren zum Dosieren und Dosiervorrichtung
US20240314479A1 (en) * 2023-03-14 2024-09-19 Apple Inc. Embedded waterproof membrane
NL2034868B1 (en) * 2023-05-19 2024-12-03 Metin Holding B V Device and method for draining blood from a sample tube and a needle for use in such device
WO2025164600A1 (ja) * 2024-01-30 2025-08-07 東ソー株式会社 免疫反応試薬、その製造方法及び免疫反応試薬キット
CN118335585B (zh) * 2024-06-11 2024-09-27 中微半导体设备(上海)股份有限公司 一种下电极组件和等离子处理装置
CN119199107B (zh) * 2024-11-27 2025-03-07 成都医芯华源生物科技有限公司 一种荧光免疫层析的定量检测装置

Family Cites Families (428)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705100A (en) 1970-08-25 1972-12-05 Amicon Corp Blood fractionating process and apparatus for carrying out same
US4212742A (en) 1978-05-25 1980-07-15 United States Of America Filtration apparatus for separating blood cell-containing liquid suspensions
US4225410A (en) 1978-12-04 1980-09-30 Technicon Instruments Corporation Integrated array of electrochemical sensors
US4228015A (en) 1979-01-29 1980-10-14 Baxter Travenol Laboratories, Inc. Plasma treatment apparatus
US4301414A (en) 1979-10-29 1981-11-17 United States Surgical Corporation Disposable sample card and method of making same
US4301412A (en) 1979-10-29 1981-11-17 United States Surgical Corporation Liquid conductivity measuring system and sample cards therefor
US4381775A (en) 1980-02-05 1983-05-03 Takeda Chemical Industries, Ltd. Method for low pressure filtration of plasma from blood
DE3171592D1 (en) 1980-09-25 1985-09-05 Terumo Corp Plasma separator
US4436610A (en) 1980-12-15 1984-03-13 Transidyne General Corporation Apparatus for measuring electrochemical activity
US4397725A (en) 1980-12-15 1983-08-09 Transidyne General Corp. Apparatus for measuring electrochemical activity
US4336121A (en) 1980-12-15 1982-06-22 Transidyne General Corporation Apparatus for measuring electrochemical activity
SE8102772L (sv) 1981-05-04 1982-11-05 Sven Staffan Folestad Forfarande for laserinducerad fluoriscensdetektering och anordning for genomforande av forfarandet
NL8202703A (nl) 1981-10-01 1983-05-02 Cobe Lab Werkwijze en inrichting voor het afscheiden van vloeistoffiltraten, die vrij zijn van deeltjes groter dan een voorafbepaalde afmeting, uit vloeistofmengsels van de deeltjes.
US4540492A (en) 1981-11-16 1985-09-10 Millipore Corporation Method and apparatus for treating whole blood
US4820129A (en) 1982-06-08 1989-04-11 Altex Scientific, Inc. Pressure measurement in fluid pump systems
DE3473512D1 (en) 1983-04-15 1988-09-22 Agency Science & Tech Chemical manipulator
US4735718A (en) 1983-05-04 1988-04-05 Millipore Corporation Multilayer membrane separator
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5221605A (en) 1984-10-31 1993-06-22 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US4786394A (en) 1985-08-29 1988-11-22 Diamond Sensor Systems, Inc. Apparatus for chemical measurement of blood characteristics
US4799393A (en) 1985-09-03 1989-01-24 Technicon Instruments Corporation Combined closed and open tube sampling apparatus and method
US4675300A (en) 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
US6316607B1 (en) 1986-04-30 2001-11-13 Igen International, Inc. Electrochemiluminescent assays
US6165729A (en) 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US6881536B1 (en) 1986-04-30 2005-04-19 Bioveris Corporation Particle based electrochemiluminescent assays
US5770459A (en) 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
WO1987006706A1 (en) 1986-04-30 1987-11-05 Igen, Inc. Electrochemiluminescent assays
US5147806A (en) 1988-04-29 1992-09-15 Igen, Inc. Method and apparatus for conducting electrochemiluminescence measurements
US6271041B1 (en) 1986-04-30 2001-08-07 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5635347A (en) 1986-04-30 1997-06-03 Igen, Inc. Rapid assays for amplification products
US6451225B1 (en) 1986-04-30 2002-09-17 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5591581A (en) 1986-04-30 1997-01-07 Igen, Inc. Electrochemiluminescent rhenium moieties and methods for their use
US4965049A (en) 1986-07-11 1990-10-23 Beckman Instruments, Inc. Modular analyzer system
DE3627814A1 (de) 1986-08-16 1988-02-25 Fresenius Ag Vorrichtung zur bestimmung des haematokrit
US4762594A (en) 1987-01-29 1988-08-09 Medtest Systems, Inc. Apparatus and methods for sensing fluid components
US4833087A (en) 1987-02-27 1989-05-23 Eastman Kodak Company Disposable container configured to produce uniform signal
US5935779A (en) 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5074977A (en) 1987-05-05 1991-12-24 The Washington Technology Center Digital biosensors and method of using same
US4929426A (en) 1987-11-02 1990-05-29 Biologix, Inc. Portable blood chemistry measuring apparatus
DK163194C (da) 1988-12-22 1992-06-22 Radiometer As Fremgangsmaade ved fotometrisk in vitro bestemmelse af en blodgasparameter i en blodproeve
US5298224A (en) 1988-01-14 1994-03-29 Novo Nordisk A/S Apparatus for determination of the coagulation time of a blood sample
AU3342689A (en) 1988-03-24 1989-10-16 Igen Incorporated Luminescent chimeric proteins
US5093268A (en) 1988-04-28 1992-03-03 Igen, Inc. Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena
US6702986B1 (en) 1988-04-29 2004-03-09 Igen International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US4887458A (en) 1988-09-21 1989-12-19 Separation Techology, Inc. Hematocrit reader apparatus and method
US5962218A (en) 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5068088A (en) 1988-11-03 1991-11-26 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5705402A (en) 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5798083A (en) 1988-11-03 1998-08-25 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration and chemiluminescence detection
US6448091B1 (en) 1988-11-03 2002-09-10 Igen International, Inc. Method and apparatus for improved luminescence assays using particle concentration chemiluminescence detection
US5061445A (en) 1988-11-03 1991-10-29 Igen, Inc. Apparatus for conducting measurements of electrochemiluminescent phenomena
US5779976A (en) 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5247243A (en) 1988-11-03 1993-09-21 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
US5746974A (en) 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
CA2002083C (en) 1988-11-03 2001-01-09 Haresh P. Shah Enhanced electrochemiluminescence
US5296191A (en) 1988-11-03 1994-03-22 Igen, Inc. Method and apparatus for conducting electrochemiluminescent measurements
JP2685544B2 (ja) 1988-11-11 1997-12-03 株式会社日立製作所 血液フィルタおよび血液検査方法並びに血液検査装置
US5139328A (en) 1989-05-24 1992-08-18 Separation Technology, Inc. Noncontact hematocrit reader apparatus and method
US5133937A (en) * 1989-06-01 1992-07-28 Iniziative Marittime, 1991 S.R.L. Analysis system having a removable reaction cartridge and temperature control
US5324457A (en) 1989-10-02 1994-06-28 Board Of Regents, The University Of Tx System Devices and methods for generating electrogenerated chemiluminescence
US5328822A (en) 1990-04-23 1994-07-12 Solid State Farms, Inc. Apparatus and method for sedimentation based blood analysis
US5143084A (en) 1990-05-24 1992-09-01 Spacelabs, Inc. Disposable cartridge for sampling and analyzing body fluids
US5130254A (en) 1990-05-25 1992-07-14 E. I. Du Pont De Nemours And Company Method for pipetting liquid from a sealed container
US5208163A (en) 1990-08-06 1993-05-04 Miles Inc. Self-metering fluid analysis device
US5096582A (en) 1990-09-25 1992-03-17 Millipore Corporation Tangential flow filtration apparatus
ZA92804B (en) 1991-02-06 1992-12-30 Igen Inc Methods and apparatus for improved luminescence assays
US5139685A (en) 1991-03-26 1992-08-18 Gds Technology, Inc. Blood separation filter assembly and method
US5155039A (en) 1991-07-22 1992-10-13 Chrisope Technologies, Inc. Apparatus for methods for preserving, transporting storing, re-hydrating and delivering viable micro-organisms
CA2074671A1 (en) 1991-11-04 1993-05-05 Thomas Bormann Device and method for separating plasma from a biological fluid
ZA929351B (en) 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
ZA929319B (en) 1991-12-11 1993-05-24 Igen Inc Method for exponential amplification of nucleic acid by a single unpaired primer.
DE69224285T2 (de) 1991-12-13 1998-07-23 Dade Int Inc Verfahren zum reinigen pipetten in einem fluessigkeitanalyseapparat
DK203191D0 (da) 1991-12-19 1991-12-19 Novo Nordisk As Fremgangsmaade og apparat til bestemmelse af relevante blodparametre
US5223219A (en) 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US5405510A (en) 1992-05-18 1995-04-11 Ppg Industries, Inc. Portable analyte measuring system for multiple fluid samples
US5223718A (en) 1992-08-10 1993-06-29 Alcor, Inc. Method and apparatus for quantifying thermal oxidation tester tube deposits
US5279797A (en) 1992-10-05 1994-01-18 Avl Scientific Corporation Disposable liquid reagent cartridge and receptacle therefor
US5316730A (en) 1992-12-07 1994-05-31 Xylum Corporation Disposable cartridge for investigating physical properties of blood
US5500187A (en) 1992-12-08 1996-03-19 Westinghouse Electric Corporation Disposable optical agglutination assay device and method for use
US5302348A (en) 1992-12-10 1994-04-12 Itc Corporation Blood coagulation time test apparatus and method
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
AU6245694A (en) 1993-02-25 1994-09-14 Diametrics Medical, Inc. Portable immediate response medical analyzer
WO1994019683A1 (en) 1993-02-25 1994-09-01 Diametrics Medical, Inc. Disposable electrochemical measurement cartridge
US5466416A (en) 1993-05-14 1995-11-14 Ghaed; Ali Apparatus and methods for carrying out electrochemiluminescence test measurements
GB9311988D0 (en) 1993-06-10 1993-07-28 Pall Corp Device and method for separating plasma from a blood product
US5821399A (en) 1993-07-16 1998-10-13 I-Stat Corporation Automatic test parameters compensation of a real time fluid analysis sensing device
US5522255A (en) 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
CA2172248C (en) 1993-09-22 2003-12-30 John Kenten Self-sustained sequence replication electrochemiluminescent nucleic acid assay
US5558838A (en) 1993-09-29 1996-09-24 Becton Dickinson And Company Sample preparation apparatus
US5416026A (en) 1993-10-04 1995-05-16 I-Stat Corporation Method for detecting the change in an analyte due to hemolysis in a fluid sample
CA2175056A1 (en) 1993-10-28 1995-05-04 Imants R. Lauks Fluid sample collection and introduction device
ATE226726T1 (de) 1994-05-19 2002-11-15 Troell Martha T Verfahren und vorrichtung zur sammlung, lagerung und echtzeitanalyse von blut und anderen körperflüssigkeiten
US5602037A (en) 1994-06-30 1997-02-11 Dade International, Inc. Combination reagent holding and test device
US5888826A (en) 1994-06-30 1999-03-30 Dade Behring Inc. Combination reagent holding and test device
FR2723735B1 (fr) 1994-08-18 1996-10-31 Abx Sa Boitier a branchement automatique pour distribution de reactifs dans un appareil notamment un analyseur hematologique.
US5786141A (en) * 1994-08-26 1998-07-28 Bard; Allen J. Electrogenerated chemiluminescence labels for analysis and/or referencing
US5627041A (en) 1994-09-02 1997-05-06 Biometric Imaging, Inc. Disposable cartridge for an assay of a biological sample
US5504011A (en) 1994-10-21 1996-04-02 International Technidyne Corporation Portable test apparatus and associated method of performing a blood coagulation test
US5744367A (en) 1994-11-10 1998-04-28 Igen International, Inc. Magnetic particle based electrochemiluminescent detection apparatus and method
US5728352A (en) 1994-11-14 1998-03-17 Advanced Care Products Disposable electronic diagnostic instrument
US5527710A (en) 1994-12-02 1996-06-18 Igen, Inc. Rate measurements of biomolecular reactions using electrochemiluminescence
US5643713A (en) 1995-06-07 1997-07-01 Liang; Pam Electrochemiluminescent monitoring of compounds
US6316180B1 (en) 1995-01-04 2001-11-13 Igen International, Inc. Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays
US20010003647A1 (en) 1995-06-07 2001-06-14 Ji Sun Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same
US6852502B1 (en) 1995-06-06 2005-02-08 Bioveris Corporation Electrochemiluminescent enzyme biosensors
US5641623A (en) 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
WO1996021154A1 (en) 1995-01-06 1996-07-11 Igen, Inc. Electrogenerated chemiluminescence through enhanced particle luminescence
US5610075A (en) 1995-01-17 1997-03-11 Stahl-Rees; Marianne Competitive electrochemiluminescence assays for endotoxins using a ruthenium label
CN1192097C (zh) * 1995-03-10 2005-03-09 梅索磅秤技术有限公司 多阵列、多特异性的电化学发光检验
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
WO1996033411A1 (en) 1995-04-18 1996-10-24 Igen, Inc. Electrochemiluminescence of rare earth metal chelates
WO1996035697A1 (en) 1995-05-08 1996-11-14 Igen, Inc. Electrochemiluminescent metal chelate labels and means for detection
US5679519A (en) 1995-05-09 1997-10-21 Oprandy; John J. Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
ES2268706T3 (es) 1995-05-09 2007-03-16 Beckman Coulter, Inc. Dispositivos y procedimientos para separar componentes celulares de la sangre de la porcion liquida de la sangre.
AU5920696A (en) 1995-05-18 1996-11-29 Igen, Inc. Method for derivitizing electrodes and assay methods using s uch derivitized electrodes
US5599447A (en) 1995-06-06 1997-02-04 Millipore Investment Holdings Limited Manifold apparatus for tangential flow filtration apparatus
CA2223027A1 (en) 1995-06-07 1996-12-19 Igen, Inc. Electrochemiluminescent enzyme immunoassay
US6099760A (en) 1995-06-07 2000-08-08 Igen, Inc. Hydrogen peroxide based ECL
WO1996041155A1 (en) 1995-06-07 1996-12-19 Igen, Inc. An improved electrochemiluminescence method
WO1996041177A1 (en) 1995-06-07 1996-12-19 Igen, Inc. Simultaneous assay method using lanthanide chelates as the luminophore for multiple labels
EP0871539B1 (en) 1995-06-16 2002-02-20 University of Washington Tangential flow planar microfabricated fluid filter
US5629209A (en) 1995-10-19 1997-05-13 Braun, Sr.; Walter J. Method and apparatus for detecting viscosity changes in fluids
US5981294A (en) 1995-11-29 1999-11-09 Metrika, Inc. Device for blood separation in a diagnostic device
US5736404A (en) 1995-12-27 1998-04-07 Zia Yassinzadeh Flow detection appartus and method
US5743861A (en) 1996-01-23 1998-04-28 Abbott Laboratories Blood collection device
US5804400A (en) 1996-02-05 1998-09-08 Igen International, Inc. Electrochemiluminescent assay
US5851488A (en) 1996-02-29 1998-12-22 Biocircuits Corporation Apparatus for automatic electro-optical chemical assay determination
US5824217A (en) 1996-03-27 1998-10-20 Millipore Corporation Membrane filtration apparatus
US5948684A (en) * 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6399023B1 (en) 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
US6193864B1 (en) 1996-05-16 2001-02-27 Sendx Medical, Inc. Locking sensor cartridge with integral fluid ports, electrical connections, and pump tube
US5980830A (en) 1996-05-20 1999-11-09 Sendx Medical, Inc. Portable modular blood analyzer with simplified fluid handling sequence
US5885533A (en) 1996-05-20 1999-03-23 Sendx Medical, Inc. Integral fluid and waste container for blood analyzer
US6112888A (en) 1996-06-28 2000-09-05 W. R. Grace & Co.-Conn. Non-reclosable packages containing desiccant matrix
US6391265B1 (en) 1996-08-26 2002-05-21 Biosite Diagnostics, Inc. Devices incorporating filters for filtering fluid samples
EP0939891A1 (en) 1996-11-15 1999-09-08 BioChem Immunosystems (U.S.), Inc. Open vial aspirator and probe washer
US5856172A (en) 1997-01-03 1999-01-05 Quality Technologies, Llc Preservation of microorganisms in a vial with a cap comprising an immobilized desiccant
US6146838A (en) 1997-03-18 2000-11-14 Igen International, Inc. Detecting water-borne parasites using electrochemiluminescence
US5747666A (en) 1997-03-26 1998-05-05 Willis; John P. Point-of-care analyzer module
US5968329A (en) 1997-05-06 1999-10-19 Diametrics Medical, Inc. Interchangeable multiple test system for portable analyzer
US7314711B2 (en) 1997-05-23 2008-01-01 Bioveris Corporation Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers
US6613583B1 (en) 1997-06-27 2003-09-02 Igen International, Inc. Electrochemiluminescent label based on multimetallic assemblies
US6071748A (en) 1997-07-16 2000-06-06 Ljl Biosystems, Inc. Light detection device
US5983734A (en) 1997-07-21 1999-11-16 Medica Corporation Modular automated diagnostic analysis apparatus with a self cleaning sample input port, an improved fluid selection port, and an improved reagent pack
US6066243A (en) 1997-07-22 2000-05-23 Diametrics Medical, Inc. Portable immediate response medical analyzer having multiple testing modules
US6082185A (en) 1997-07-25 2000-07-04 Research International, Inc. Disposable fluidic circuit cards
US5827481A (en) 1997-07-31 1998-10-27 Hewlett-Packard Company Cartridge system for effecting sample acquisition and introduction
US5919711A (en) 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
SE9703302D0 (sv) 1997-09-10 1997-09-10 Vincenzo Vassarotti Filtration cell for tangential flow filtration and filtration system making use of such cell
US6016712A (en) 1997-09-18 2000-01-25 Accumetrics Device for receiving and processing a sample
US6413783B1 (en) 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
EP1179585B1 (en) 1997-12-24 2008-07-09 Cepheid Device and method for lysis
US6635418B2 (en) 1998-02-13 2003-10-21 Igen International, Inc. Assay methods for nucleic acid in a sample
US6929953B1 (en) 1998-03-07 2005-08-16 Robert A. Levine Apparatus for analyzing biologic fluids
US6200531B1 (en) 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
CA2320296A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
EP0962773A1 (en) * 1998-06-03 1999-12-08 Mark Howard Jones Electrochemical based assay processes instrument and labels
CN1143134C (zh) 1998-06-24 2004-03-24 陈氏有限责任公司 流体样本测试系统及化验方法
US6312896B1 (en) 1998-09-17 2001-11-06 Igen Inaternational, Inc. Assays for measuring nucleic acid binding proteins and enzyme activities
US6214552B1 (en) 1998-09-17 2001-04-10 Igen International, Inc. Assays for measuring nucleic acid damaging activities
CA2254223A1 (en) 1998-11-16 2000-05-16 Biophys, Inc. Device and method for analyzing a biologic sample
US6217744B1 (en) 1998-12-18 2001-04-17 Peter Crosby Devices for testing fluid
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US6475372B1 (en) 2000-02-02 2002-11-05 Lifescan, Inc. Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations
EP1208189B1 (en) 1999-05-28 2004-10-06 Cepheid Device and method for analysing liquid samples
US6818185B1 (en) 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US6398956B1 (en) 1999-05-28 2002-06-04 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
US7288195B2 (en) 1999-05-28 2007-10-30 Bio/Data Corporation Method and apparatus for directly sampling a fluid for microfiltration
ATE333938T1 (de) * 1999-05-28 2006-08-15 Cepheid Patrone zum durchführen einer chemischen reaktion
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
KR100675698B1 (ko) * 1999-08-06 2007-02-01 써모 바이오스타, 인크. 완전한 샘플 처리 능력을 포함하는 자동화된 진료 검출 시스템
US6495104B1 (en) 1999-08-19 2002-12-17 Caliper Technologies Corp. Indicator components for microfluidic systems
US6824663B1 (en) 1999-08-27 2004-11-30 Aclara Biosciences, Inc. Efficient compound distribution in microfluidic devices
CA2382143C (en) 1999-09-03 2005-10-18 Roche Diagnostics Corporation Method, reagent and test cartridge for determining clotting time
US6534137B1 (en) 1999-10-12 2003-03-18 Cryovac, Inc. Two-component, heat-sealable films
US6319719B1 (en) 1999-10-28 2001-11-20 Roche Diagnostics Corporation Capillary hematocrit separation structure and method
US6750053B1 (en) 1999-11-15 2004-06-15 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
US6406672B1 (en) 2000-01-28 2002-06-18 Roche Diagnostics Plasma retention structure providing internal flow
US6438498B1 (en) 2000-02-10 2002-08-20 I-Stat Corporation System, method and computer implemented process for assaying coagulation in fluid samples
CN1310980A (zh) * 2000-02-29 2001-09-05 迪亚西斯公司 处理各种体液的方法和设备
US6379969B1 (en) 2000-03-02 2002-04-30 Agilent Technologies, Inc. Optical sensor for sensing multiple analytes
IL151477A0 (en) 2000-03-09 2003-04-10 Clinical Analysis Corp Medical diagnostic system
JP4733331B2 (ja) 2000-03-14 2011-07-27 マイクロニックス、インコーポレーテッド マイクロ流動体分析用デバイス
US6541262B1 (en) 2000-04-28 2003-04-01 Medtronic, Inc. Method and device for testing a sample of fresh whole blood
US8383043B2 (en) 2004-05-14 2013-02-26 Honeywell International Inc. Analyzer system
US7641856B2 (en) 2004-05-14 2010-01-05 Honeywell International Inc. Portable sample analyzer with removable cartridge
US7471394B2 (en) 2000-08-02 2008-12-30 Honeywell International Inc. Optical detection system with polarizing beamsplitter
US8071051B2 (en) 2004-05-14 2011-12-06 Honeywell International Inc. Portable sample analyzer cartridge
US7978329B2 (en) 2000-08-02 2011-07-12 Honeywell International Inc. Portable scattering and fluorescence cytometer
US6554788B1 (en) 2000-06-02 2003-04-29 Cobe Cardiovascular, Inc. Hematocrit sampling system
US7630063B2 (en) 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US7004184B2 (en) 2000-07-24 2006-02-28 The Reagents Of The University Of Michigan Compositions and methods for liquid metering in microchannels
US7277166B2 (en) 2000-08-02 2007-10-02 Honeywell International Inc. Cytometer analysis cartridge optical configuration
US7061595B2 (en) 2000-08-02 2006-06-13 Honeywell International Inc. Miniaturized flow controller with closed loop regulation
AU2001288025A1 (en) 2000-09-05 2002-03-22 Biosight Ltd. Peptide conjugated anti-cancer prodrugs
DE10046173C2 (de) 2000-09-08 2003-04-03 Inst Chemo Biosensorik Vorrichtung und Verfahren zur Separation von ungelösten Bestandteilen aus biologischen Flüssigkeiten
US20020045243A1 (en) * 2000-09-15 2002-04-18 Laska Ronald C. Fluid cartridge and method
US20020155033A1 (en) 2000-10-06 2002-10-24 Protasis Corporation Fluid Separate conduit cartridge
US6559096B1 (en) 2000-10-18 2003-05-06 Nanopore, Inc. Desiccant composition
DK1201304T3 (da) 2000-10-25 2006-11-13 Boehringer Ingelheim Micropart Mikrostruktureret platform til undersögelse af en væske
US20020098116A1 (en) 2000-12-13 2002-07-25 Fuji Photo Film Co., Ltd. Biochemical analysis system, and biochemical analysis element cartridge
US6613286B2 (en) 2000-12-21 2003-09-02 Walter J. Braun, Sr. Apparatus for testing liquid/reagent mixtures
BR0207095A (pt) 2001-02-12 2004-01-20 Immunivest Corp Método para vedar uma câmara para evitar aprisionamento de ar em um lìquido de teste, sistema de vedação para vedar uma câmara de teste para evitar aprisionamento de ar em lìquido inserido para o interior da câmara, e, cartucho que contém uma câmara de teste para utilização em aparelho para realizar análise óptica de espécimes de lìquido por meio de observação óptica
US6949377B2 (en) 2001-03-05 2005-09-27 Ho Winston Z Chemiluminescence-based microfluidic biochip
US6613280B2 (en) 2001-03-20 2003-09-02 Therox, Inc. Disposable cartridge for producing gas-enriched fluids
US20020143297A1 (en) 2001-03-30 2002-10-03 Becton, Dickinson And Company Adaptor for use with point-of-care testing cartridge
JP2003098181A (ja) * 2001-05-15 2003-04-03 Sysmex Corp 測定ユニットとそれに用いる回転バルブ
DE10130428B4 (de) 2001-06-23 2005-12-22 Boehringer Ingelheim Microparts Gmbh Verfahren zum flächenartigen Verbinden von Körpern
US20030029254A1 (en) 2001-06-26 2003-02-13 Hvidtfeldt Kristian J. Blood analyzer
US6880384B2 (en) 2001-06-26 2005-04-19 Radiometer Medical A/S Blood analyzer, blood sample handler, and method for handling a blood sample
US6808939B2 (en) 2001-06-29 2004-10-26 Igen International, Inc. ECL labels having improved non-specific binding properties, methods of using and kits containing the same
DK1412725T3 (en) 2001-06-29 2019-03-25 Meso Scale Technologies Llc Multi-well plates for LUMINESCENSE TEST MEASUREMENTS
WO2003023360A2 (en) * 2001-09-10 2003-03-20 Meso Scale Technologies, Llc Methods and apparatus for conducting multiple measurements on a sample
AU2002324947B2 (en) 2001-09-10 2007-11-15 Meso Scale Technologies, Llc. Assay buffer, compositions containing the same, and methods of using the same
ATE553835T1 (de) 2001-09-20 2012-05-15 Emd Millipore Corp Filtermodul
US20030073089A1 (en) 2001-10-16 2003-04-17 Mauze Ganapati R. Companion cartridge for disposable diagnostic sensing platforms
SE521252C2 (sv) 2001-11-21 2003-10-14 Boule Medical Ab Engångsapparat för användning vid blodprov och instrument för användning med apparaten
EP1317960A1 (en) 2001-12-06 2003-06-11 PamGene B.V. System and method for analyzing a blood sample and disposable cartridge for use in this system or method
SE0104443D0 (sv) 2001-12-28 2001-12-28 Hemocue Ab Analysis method and cuvette therefor
US7419821B2 (en) 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US7235213B2 (en) 2002-03-25 2007-06-26 Farallon Medical, Inc. System for performing blood coagulation assays and measuring blood clotting times
JP2003287532A (ja) 2002-03-28 2003-10-10 Fuji Photo Film Co Ltd 血液検査ユニット
JP3808393B2 (ja) 2002-03-28 2006-08-09 富士写真フイルム株式会社 血液検査ユニットおよび血液検査装置
GB2387130A (en) 2002-04-04 2003-10-08 Fluid Technologies Plc Hollow fibre filter membrane unit with microorganism detector, and associated usage
EP1495333A4 (en) 2002-04-17 2009-03-04 Biosafe Medical Technologies I METHOD AND DEVICE FOR HEMATOKRIT MEASUREMENT
US7285425B2 (en) 2002-05-14 2007-10-23 Siemens Medical Solutions Diagnostics Assay test system for regulating temperature
US20030224523A1 (en) 2002-05-30 2003-12-04 Thornberg John Herbert Cartridge arrangement, fluid analyzer arrangement, and methods
AU2003232169B8 (en) 2002-06-11 2008-05-08 Koninklijke Philips Electronics N.V. A disposable cartridge for characterizing particles suspended in a liquid
AU2003249350A1 (en) 2002-06-20 2004-01-06 Igen International, Inc Electrochemiluminescence flow cell and flow cell components
US20040096368A1 (en) 2002-06-28 2004-05-20 Igen International, Inc. Assay systems and components
US7569393B2 (en) 2002-06-28 2009-08-04 International Technidyne Corporation Analytical test cartridge; and, methods
DE60324738D1 (de) 2002-07-18 2009-01-02 Panasonic Corp Messvorrichtung mit einem Biosensor
US6794877B2 (en) 2002-07-31 2004-09-21 International Technidyne Corporation Apparatus and method for analytical determinations
US20070166725A1 (en) 2006-01-18 2007-07-19 The Regents Of The University Of California Multiplexed diagnostic platform for point-of care pathogen detection
US20040086872A1 (en) 2002-10-31 2004-05-06 Childers Winthrop D. Microfluidic system for analysis of nucleic acids
US7932098B2 (en) 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
SE524730C2 (sv) 2002-11-20 2004-09-21 Boule Medical Ab Blodprovsapparat
US7011794B2 (en) 2002-11-25 2006-03-14 Immunivest Corporation Upon a cartridge for containing a specimen sample for optical analysis
DE10257004A1 (de) 2002-12-06 2004-06-17 Steag Microparts Gmbh Vorrichtung zur parallelen Dosierung von Flüssigkeiten
US7422903B2 (en) 2002-12-11 2008-09-09 Instrumentation Laboratory Company Multi-analyte reference solutions
CN102620959B (zh) 2002-12-26 2015-12-16 梅索磅秤技术有限公司 检定盒及其使用方法
US20040176704A1 (en) 2003-03-04 2004-09-09 Stevens Timothy A Collection device adapted to accept cartridge for point of care system
DE602004024769D1 (de) 2003-03-17 2010-02-04 Charles River Lab Inc Methoden und zusammensetzungen für den nachweis mikrobieller verunreinigungen
USD499035S1 (en) 2003-05-01 2004-11-30 Bioveris Corporation Detection apparatus
US7247488B2 (en) 2003-05-06 2007-07-24 Medtronic, Inc. Method and kit for testing a multi-channel blood assay cartridge
US20040228765A1 (en) 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US20040228766A1 (en) 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
USD494589S1 (en) 2003-05-29 2004-08-17 Bioveris Corporation Detection device
AU2004250141A1 (en) 2003-06-13 2004-12-29 Applera Corporation Electrochemiluminescence electrode
US7247487B2 (en) 2003-06-18 2007-07-24 Ortho-Clinical Diagnostics Reducing working fluid dilution in liquid systems
DE10330804A1 (de) 2003-07-08 2005-04-28 Fresenius Medical Care De Gmbh Einwegkassette
US20050014279A1 (en) 2003-07-14 2005-01-20 Nguyen Hoa Duc Method of analysis of amine by mass spectrometry
CA2479452C (en) * 2003-08-30 2008-11-04 F.Hoffmann-La Roche Ag Method and device for determining analytes in a liquid
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US7682833B2 (en) 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
US20050074900A1 (en) 2003-10-07 2005-04-07 Morgan Nicole Y. Microfluidic flow-through immunoassay for simultaneous detection of multiple proteins in a biological sample
US7981362B2 (en) 2003-11-04 2011-07-19 Meso Scale Technologies, Llc Modular assay plates, reader systems and methods for test measurements
US8158062B2 (en) 2003-11-05 2012-04-17 Chris Dykes Disposable fluid sample collection device
US7378270B2 (en) 2003-11-10 2008-05-27 Sentec Scientific, Inc. Device for analyte measurement
US7523649B2 (en) 2003-11-26 2009-04-28 Separation Technology, Inc. Method and apparatus for ultrasonic determination of hematocrit and hemoglobin concentrations
ES2340378T3 (es) 2003-12-16 2010-06-02 Dynabyte Informationssysteme Gmbh Dispositivo de cartucho para el analisis de sangre.
DE10360814A1 (de) 2003-12-23 2005-07-28 Dade Behring Marburg Gmbh Kartusche zur Funktionskontrolle einer Vorrichtung für die Untersuchung der Blutplättchenfunktion, Verfahren zur Funktionskontrolle und Verwendung einer Testflüssigkeit
WO2005065157A2 (en) * 2003-12-23 2005-07-21 Fastraq, Inc. Point of care diagnostic platform
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US7111503B2 (en) 2004-01-22 2006-09-26 Datalog Technology Inc. Sheet-form membrane sample probe, method and apparatus for fluid concentration analysis
US7781226B2 (en) 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US20060257854A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Membrane assay system including preloaded particles
US20060257941A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements
US7439069B2 (en) 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US20060257991A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US7422905B2 (en) 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US20050227370A1 (en) 2004-03-08 2005-10-13 Ramel Urs A Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays
WO2005088300A1 (en) 2004-03-16 2005-09-22 Fuji Photo Film Co., Ltd. Assay chip
KR20050096489A (ko) 2004-03-31 2005-10-06 주식회사 올메디쿠스 혈액 내 혈구를 평면상의 기판에서 특별한 전기, 자기적인장치없이 분리 및 이송할 수 있는 필터
US20050220668A1 (en) 2004-04-06 2005-10-06 Bio/Data Corporation Disposable test device with sample volume measurement and mixing methods
USD515220S1 (en) 2004-04-13 2006-02-14 Bioveris Corporation Detection apparatus
US7399637B2 (en) 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US9101302B2 (en) 2004-05-03 2015-08-11 Abbott Diabetes Care Inc. Analyte test device
US7887750B2 (en) 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
US20050250173A1 (en) 2004-05-10 2005-11-10 Davis Charles Q Detection device, components of a detection device, and methods associated therewith
US8323564B2 (en) 2004-05-14 2012-12-04 Honeywell International Inc. Portable sample analyzer system
US7438853B2 (en) 2004-05-19 2008-10-21 Jyh-Myng Zen Photoelectrocatalytic method and photoelectrochemical detector for electrochemical analysis
EP1766400B1 (en) 2004-06-03 2009-04-15 Meso Scale Technologies, LLC Methods for conducting whole blood assays
US7299081B2 (en) 2004-06-15 2007-11-20 Abbott Laboratories Analyte test device
RU2389019C2 (ru) 2004-06-24 2010-05-10 БАЙЕР ХЕЛТКЭР ЭлЭлСи Картридж и приспособление для выдачи датчиков
US7306727B2 (en) 2004-09-21 2007-12-11 Millipore Corporation Disposable tangential flow filtration device holder
WO2006034525A1 (en) 2004-09-28 2006-04-06 Cleveland Biosensors Pty Ltd Microfluidic device
US7608042B2 (en) 2004-09-29 2009-10-27 Intellidx, Inc. Blood monitoring system
CA2581709C (en) 2004-10-01 2014-06-17 Chempaq A/S A method for calibrating a particle counting apparatus
US7704730B2 (en) 2004-10-14 2010-04-27 Meso Scale Technologies, Llc Multiplexed assay methods
CN100534619C (zh) 2004-10-15 2009-09-02 西门子公司 对可通过导管进入测量室中的液态测量样品进行电化学测量的方法和相应的布置
CA2584466A1 (en) 2004-10-18 2006-04-27 Bioveris Corporation Systems and methods for obtaining, storing, processing and utilizing immunologic information of an individual or population
CN101061384A (zh) 2004-10-21 2007-10-24 拜尔保健有限公司 传感器分配装置和抽出传感器的机构
US20060094028A1 (en) 2004-11-04 2006-05-04 Welch Allyn, Inc. Rapid diagnostic assay
US20080227219A1 (en) 2004-11-17 2008-09-18 Frank Gamez Electrochemiluminescent assay
US20060275841A1 (en) 2004-12-20 2006-12-07 Martin Blankfard Assay method and apparatus with reduced sample matrix effects
US20060165558A1 (en) * 2004-12-21 2006-07-27 Thomas Witty Cartridge for diagnostic assays
JP4422623B2 (ja) * 2005-01-17 2010-02-24 株式会社日立ハイテクノロジーズ 化学分析装置および化学分析カートリッジ
US20060177883A1 (en) 2005-02-08 2006-08-10 Saladax Biomedical Inc. 5-Fluoro-uracil immunoassay
US8028566B2 (en) 2005-02-10 2011-10-04 Chempaq A/S Dual sample cartridge and method for characterizing particles in liquid
CA2597496A1 (en) 2005-02-10 2006-08-17 Chempaq A/S Dual sample cartridge and method for characterizing particles in liquid
US20060195058A1 (en) 2005-02-14 2006-08-31 Gable Jennifer H Methods and apparatus for extracting and analyzing a bodily fluid
JP2008532048A (ja) 2005-03-07 2008-08-14 ノブックス システムズ インコーポレーテッド 自動分析器
ITBO20050203A1 (it) 2005-03-30 2006-09-30 Medical Service S R L Modulo monouso,pompa peristaltica,apparecchiatura per il trattamento del sangue e sistema costituito dall'associazione del modulo monouso e dell'apparecchiatura
US8206650B2 (en) 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
CA2507323A1 (en) 2005-05-13 2006-11-13 Chromedx Inc. Diagnostic whole blood and plasma apparatus
US7595169B2 (en) 2005-04-27 2009-09-29 Accumetrics, Inc. Method for determining percent platelet aggregation
GB0508983D0 (en) 2005-05-03 2005-06-08 Oxford Gene Tech Ip Ltd Cell analyser
US8841076B2 (en) 2005-05-09 2014-09-23 Theranos, Inc. Systems and methods for conducting animal studies
ES2752000T3 (es) 2005-05-09 2020-04-02 Biofire Diagnostics Llc Análisis biológico autónomo
US20070036026A1 (en) 2005-05-16 2007-02-15 Laibinis Paul E Magnetic Particle Systems and Methods
US20060263818A1 (en) 2005-05-23 2006-11-23 Axel Scherer High throughput multi-antigen microfluidic fluorescence immunoassays
JP2006329764A (ja) * 2005-05-25 2006-12-07 Aisin Seiki Co Ltd 液体収容容器および分析装置
US8377398B2 (en) 2005-05-31 2013-02-19 The Board Of Regents Of The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
US20070116600A1 (en) 2005-06-23 2007-05-24 Kochar Manish S Detection device and methods associated therewith
WO2007002579A2 (en) 2005-06-23 2007-01-04 Bioveris Corporation Assay cartridges and methods for point of care instruments
US20100291588A1 (en) 2005-06-24 2010-11-18 The Board Of Regents Of The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
WO2007005626A1 (en) 2005-07-01 2007-01-11 Bioveris Corporation Compositions and methods for detecting, amplifying, and/or isolating nucleic acids
JP4995197B2 (ja) 2005-07-01 2012-08-08 ハネウェル・インターナショナル・インコーポレーテッド ３ｄ流体力学的集束を有する成形カートリッジ
US8361410B2 (en) 2005-07-01 2013-01-29 Honeywell International Inc. Flow metered analyzer
WO2007005973A2 (en) 2005-07-01 2007-01-11 Honeywell International, Inc. A microfluidic card for rbc analysis
US20070054293A1 (en) 2005-08-30 2007-03-08 California Institute Of Technology Microfluidic chaotic mixing systems and methods
US8007670B2 (en) 2005-09-09 2011-08-30 Tangenx Technology Corporation Laminated cassette device and methods for making same
AU2006299414A1 (en) * 2005-09-30 2007-04-12 Caliper Life Sciences, Inc. Microfluidic device for purifying a biological component using magnetic beads
EP2347825B1 (en) 2005-10-28 2016-10-19 ARKRAY, Inc. Analytical cartridge
CN101356715B (zh) 2005-12-02 2012-07-18 恩特格里公司 用于泵中的阀的排序的系统和方法
JP5030110B2 (ja) 2005-12-21 2012-09-19 サムスン エレクトロニクス カンパニー リミテッド バイオメモリディスクドライブ装置及びそれを用いた分析方法
JP2009521684A (ja) 2005-12-22 2009-06-04 ハネウェル・インターナショナル・インコーポレーテッド 携帯用サンプル分析装置のカートリッジ
US7485153B2 (en) 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
US7384549B2 (en) 2005-12-29 2008-06-10 Spf Innovations, Llc Method and apparatus for the filtration of biological solutions
CN101389947B (zh) 2005-12-29 2013-08-21 霍尼韦尔国际公司 微流格式的测定工具
WO2007106580A2 (en) * 2006-03-15 2007-09-20 Micronics, Inc. Rapid magnetic flow assays
ES2692380T3 (es) 2006-03-24 2018-12-03 Handylab, Inc. Método para realizar PCR con un cartucho con varias pistas
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
WO2007114794A1 (en) 2006-03-31 2007-10-11 Nam Trung Nguyen Active control for droplet-based microfluidics
US7822510B2 (en) 2006-05-09 2010-10-26 Advanced Liquid Logic, Inc. Systems, methods, and products for graphically illustrating and controlling a droplet actuator
US7939021B2 (en) 2007-05-09 2011-05-10 Advanced Liquid Logic, Inc. Droplet actuator analyzer with cartridge
US8137626B2 (en) 2006-05-19 2012-03-20 California Institute Of Technology Fluorescence detector, filter device and related methods
EP2035540A2 (en) * 2006-06-15 2009-03-18 Stratagene System for isolating biomolecules from a sample
US20080153078A1 (en) 2006-06-15 2008-06-26 Braman Jeffrey C System for isolating biomolecules from a sample
US8585279B2 (en) 2006-06-21 2013-11-19 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
US8870446B2 (en) 2006-06-21 2014-10-28 Spinomix S.A. Device and method for manipulating and mixing magnetic particles in a liquid medium
US8999732B2 (en) 2006-06-21 2015-04-07 Spinomix, S.A. Method for manipulating magnetic particles in a liquid medium
US9149564B2 (en) 2006-06-23 2015-10-06 The Regents Of The University Of California Articles comprising large-surface-area bio-compatible materials and methods for making and using them
US20100240022A1 (en) 2006-06-23 2010-09-23 Mcneely Michael R Reagent preparation and valving design for liquid testing
ITUD20060177A1 (it) 2006-07-14 2008-01-15 Sire Analytical Systems Srl Apparecchiatura integrata e metodo per la rilevazione di stati infiammatori presenti in un campione di sangue intero
GB0618966D0 (en) * 2006-09-26 2006-11-08 Iti Scotland Ltd Cartridge system
WO2008147382A1 (en) 2006-09-27 2008-12-04 Micronics, Inc. Integrated microfluidic assay devices and methods
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US8008034B2 (en) 2006-10-13 2011-08-30 Theranos, Inc. Reducing optical interference in a fluidic device
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8765076B2 (en) 2006-11-14 2014-07-01 Handylab, Inc. Microfluidic valve and method of making same
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
WO2008140568A2 (en) 2006-11-15 2008-11-20 Idaho Technology, Inc. High density self-contained biological analysis
US20100117666A1 (en) 2006-12-28 2010-05-13 Wada Henry G Method and System for Internal Standardization of Assays
JPWO2008096562A1 (ja) * 2007-02-06 2010-05-20 コニカミノルタエムジー株式会社 マイクロチップ検査システム、マイクロチップ、マイクロチップ検査装置及びプログラム
KR101422467B1 (ko) 2007-02-08 2014-07-24 삼성전자주식회사 미세유체 칩 내의 형광을 검출하기 위한 시스템 및 형광검출 방법
NL1033365C2 (nl) 2007-02-09 2008-08-12 Medavinci Dev B V Inrichting en werkwijze voor scheiden en analyseren van bloed.
US20100203521A1 (en) 2007-04-02 2010-08-12 Boston Medical Center Corporation Method for bacterial lysis
JP2010525322A (ja) 2007-04-20 2010-07-22 クイデル コーポレイション 統合乾燥剤付きの分析装置
EP2160604A4 (en) 2007-05-18 2014-08-27 Axela Inc CHEMICAL REACTION DEVICE HAVING INTEGRATED OPTICAL AND FLUID CONTROL ELEMENTS
JP2009013164A (ja) 2007-06-04 2009-01-22 Hitachi High-Technologies Corp 高密度リポ蛋白測定装置および分離方法
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
GB0714040D0 (en) 2007-07-19 2007-08-29 Xceleron Ltd Quantification of analytes
GB0715171D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Sample processor
JP2009042103A (ja) * 2007-08-09 2009-02-26 Sony Corp 基板、これを用いた反応処理装置並びに反応制御方法
US8835184B2 (en) 2007-09-14 2014-09-16 Biosensia Patents Limited Analysis system
US8460528B2 (en) 2007-10-17 2013-06-11 Advanced Liquid Logic Inc. Reagent storage and reconstitution for a droplet actuator
KR100907253B1 (ko) 2007-10-17 2009-07-10 한국전자통신연구원 랩온어칩 및 그 구동 방법
KR100886914B1 (ko) 2007-11-01 2009-03-09 주식회사 아이센스 혈액 분석 장치용 카트리지 및 이를 이용한 혈액 분석 장치
JP2009119386A (ja) * 2007-11-15 2009-06-04 Fujifilm Corp マイクロ流体チップおよびそれを用いた液体混合方法
US8372343B2 (en) 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
KR101608749B1 (ko) 2008-01-21 2016-04-06 삼성전자주식회사 박막 원심분리 분석 장치 및 이를 이용한 분석 방법
KR101605575B1 (ko) 2008-03-31 2016-03-22 키아겐 라케 콘스탄스 게엠베하 샘플 홀더 및 이를 이용하는 방법
JPWO2009125676A1 (ja) * 2008-04-09 2011-08-04 コニカミノルタエムジー株式会社 検査システム
JP4557266B2 (ja) 2008-04-30 2010-10-06 キヤノンアネルバ株式会社 質量分析装置及び質量分析方法
KR101102532B1 (ko) * 2008-07-10 2012-01-03 삼성전자주식회사 시약 카트리지, 시약 카트리지를 구비하는 미세유동장치, 그 제조방법, 및 이를 이용한 시료분석방법
US8021873B2 (en) 2008-07-16 2011-09-20 Boston Microfluidics Portable, point-of-care, user-initiated fluidic assay methods and systems
US8623638B2 (en) 2008-08-08 2014-01-07 Neal Solomon Intelligent multifunctional medical device apparatus and components
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
WO2010040103A1 (en) 2008-10-03 2010-04-08 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
US9383355B2 (en) 2008-10-10 2016-07-05 Rutgers, The State University Of New Jersey Methods and related devices for continuous sensing utilizing magnetic beads
US8046175B2 (en) 2008-10-13 2011-10-25 Actherm Inc Analytical strip reading apparatus and the analyical strip used therein
CN106040330B (zh) 2008-11-06 2018-09-18 皇家飞利浦电子股份有限公司 试管和用于鉴定试管的方法
DK2376226T3 (en) 2008-12-18 2018-10-15 Opko Diagnostics Llc IMPROVED REAGENT STORAGE IN MICROFLUIDIC SYSTEMS AND RELATED ARTICLES AND PROCEDURES
JP5782384B2 (ja) 2009-02-03 2015-09-24 ネットバイオ・インコーポレーテッドＮｅｔＢｉｏ， Ｉｎｃ． 未処理試料から核酸を単離するための自己完結型装置および精製方法
WO2010091264A2 (en) 2009-02-06 2010-08-12 Perkinelmer Health Sciences, Inc. Simultaneous detection of estrogen and non estrogen steroids
US8640555B2 (en) 2009-02-09 2014-02-04 Bioaccel Performance
JP5608943B2 (ja) 2009-03-31 2014-10-22 マイクロ化学技研株式会社 血漿分離装置及び方法
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
EP2419217B1 (en) 2009-04-13 2014-11-12 Micronics, Inc. Microfluidic clinical analyzer
JP2010266236A (ja) 2009-05-12 2010-11-25 Sysmex Corp 試料分析装置
EP2440672B1 (en) * 2009-06-12 2016-03-30 Micronics, Inc. Compositions and methods for dehydrated storage of on-board reagents in microfluidic devices
EP3792634A3 (en) * 2009-07-17 2021-06-02 Myriad Genetics, Inc. Method of assaying 5-fu
WO2011008972A1 (en) * 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
EP2281631B1 (en) 2009-08-07 2016-12-14 Atonomics A/S Modular microfluidic sample preparation system and method of mixing and delivering a sample fluid.
WO2011027092A1 (en) 2009-09-01 2011-03-10 F. Hoffmann-La Roche Ag Micro-fluidic structures
US20110143378A1 (en) 2009-11-12 2011-06-16 CyVek LLC. Microfluidic method and apparatus for high performance biological assays
JP5433453B2 (ja) 2010-02-08 2014-03-05 株式会社堀場製作所 液体試料分析機器
JP2011180117A (ja) 2010-02-08 2011-09-15 Horiba Ltd 分析用液体容器
JP5506440B2 (ja) 2010-02-08 2014-05-28 株式会社堀場製作所 液体試料定量器
ATE542136T1 (de) 2010-03-15 2012-02-15 Boehringer Ingelheim Int Vorrichtung und verfahren zur manipulation oder untersuchung einer flüssigen probe
US8476079B2 (en) 2010-04-30 2013-07-02 Abbott Point Of Care Inc. Reagents for reducing leukocyte interference in immunoassays
CN202256273U (zh) 2010-05-26 2012-05-30 刘晓川 便携式糖化血红蛋白仪
US20110312759A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Genetic analysis loc with reagent reservoir
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
WO2012024543A1 (en) 2010-08-18 2012-02-23 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
EP2442092A3 (en) 2010-08-23 2013-05-29 HORIBA, Ltd. Cell analysis cartridge with impedance measurement channel
JP5432862B2 (ja) 2010-08-23 2014-03-05 株式会社堀場製作所 体液分析器具
US8468680B2 (en) 2010-08-24 2013-06-25 Roche Diagnostics Operations, Inc. Biosensor test member and method for making the same
CN105911196B (zh) 2010-10-29 2019-04-23 恩姆菲舍尔科技公司 用于样品制备和分析的自动化系统的系统布局
US20120190128A1 (en) 2011-01-21 2012-07-26 Atonomics A/S Modular microfluidic sample preparation system and method of mixing and delivering a sample fluid
GB201102037D0 (en) 2011-02-07 2011-03-23 Multi Sense Technologies Ltd Microfluidics based assay device
WO2012136695A1 (en) 2011-04-06 2012-10-11 Biomagnetics Ab Device comprising rows of magnetic elements in channels and compartments
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
AU2012327218C1 (en) 2011-11-30 2015-12-24 Wellstat Diagnostics, Llc. Filtration Module
US20150047978A1 (en) 2012-03-13 2015-02-19 Piramal Enterprises Limited Biosensor having nanostructured electrodes
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
US9821312B2 (en) 2012-09-12 2017-11-21 Bio-Rad Laboratories, Inc. Integrated microfluidic system, method and kit for performing assays

Also Published As

Publication number Publication date
US9081001B2 (en) 2015-07-14
CA2873459A1 (en) 2013-11-21
AU2013262816A1 (en) 2014-12-04
US9075042B2 (en) 2015-07-07
US20130337432A1 (en) 2013-12-19
AU2013262815A1 (en) 2014-12-04
EP2849632A2 (en) 2015-03-25
WO2013173524A9 (en) 2014-01-09
CN104427929A (zh) 2015-03-18
CN104471384A (zh) 2015-03-25
EP2849632A4 (en) 2016-01-20
WO2013173525A1 (en) 2013-11-21
AU2013262815B2 (en) 2016-09-29
WO2013173524A2 (en) 2013-11-21
WO2013173524A3 (en) 2014-02-20
AU2013262816B2 (en) 2016-06-23
EP2852834A4 (en) 2016-01-20
JP2015516583A (ja) 2015-06-11
US20130315780A1 (en) 2013-11-28
JP2015522801A (ja) 2015-08-06
EP2852834A1 (en) 2015-04-01
US20150266024A1 (en) 2015-09-24

Similar Documents

Publication Publication Date Title
AU2013262815B2 (en) Clinical diagnostic system including instrument and cartridge
US9213043B2 (en) Clinical diagnostic system including instrument and cartridge
US10261041B2 (en) Integrated disposable chip cartridge system for mobile multiparameter analyses of chemical and/or biological substances
JP5127878B2 (ja) アッセイカートリッジ及び同アッセイカートリッジを用いた方法
CN102844425B (zh) 样本分析系统及其使用方法
CA3028780C (en) Assay cartridges and methods of using the same
JP4627395B2 (ja) 分析用カートリッジ及び送液制御装置
EP2810044B1 (en) Mechanical washing and measuring device for performing analyses
US20160041193A1 (en) Method for operating a system for the integrated and automated analysis of dna or protein
JPWO2001013127A1 (ja) 分析用カートリッジ及び送液制御装置
CN101262948A (zh) 基于流过阵列的液体流的测定
WO2004062804A1 (en) Microfluidic biochip with breakable seal
EP1561507A1 (en) System for characterising a fluid, microfluidic device for characterising or analysing concentration components, a method of characterising or analysing such concentrations and a measurement device
US20220357347A1 (en) Device and method to evaluate a fluid sample on a single-use multianalyte consumable
JP2009121912A (ja) マイクロチップ
US20150238954A1 (en) Fluid analysis cartridge
KR20240177093A (ko) 현장검사를 위한 휴대용 바이오칩
HK1117189B (en) Assay cartridges and methods of using the same

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20180515