ES2185704T3 - Procedimiento y aparato para la recogida, almacenamiento y analisis en tiempo real de sangre y otros fluidos corporales. - Google Patents
Procedimiento y aparato para la recogida, almacenamiento y analisis en tiempo real de sangre y otros fluidos corporales.Info
- Publication number
- ES2185704T3 ES2185704T3 ES95918455T ES95918455T ES2185704T3 ES 2185704 T3 ES2185704 T3 ES 2185704T3 ES 95918455 T ES95918455 T ES 95918455T ES 95918455 T ES95918455 T ES 95918455T ES 2185704 T3 ES2185704 T3 ES 2185704T3
- Authority
- ES
- Spain
- Prior art keywords
- fraction
- collection chamber
- sample collection
- cellular
- collection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5002—Partitioning blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
SE PRESENTA UN APARATO PARA RECOGER, SEPARAR, COMPROBAR Y ALMACENAR PEQUEÑAS CANTIDADES DE SANGRE O DE OTROS FLUIDOS CORPORALES "IN SITU". EL APARATO INCLUYE UNA CAMARA DE RECOGIDA QUE ESTA APRETADA POR UN FILTRO HECHO DE UNA LAMINA FINA DE MATERIAL FIBROSO QUE TIENE UN TAMAÑO DE PORO MEDIO INFERIOR A 3 MICRONES. EL MATERIAL FIBROSO HA SIDO TRATADO CON UNA MEZCLA QUE CONTIENE ENTRE UN 1 Y UN 40% DE PESO PARTIDO POR VOLUMEN DE CARBOHIDRATO Y ENTRE UN 0.1 Y UN 15% DE PESO PARTIDO POR VOLUMEN DE PROTEINA NO ESPECIFICA. LA MEZCLA PREFERIDA DE CARBOHIDRATO/PROTEINA COMPRENDE ALREDEDOR DE UN 10% DE MANITOL Y ALREDEDOR DE UN 6% DE ALBUMINA. LA SANGRE U OTROS FLUIDOS SE MUEVEN A TRAVES DE LA TARJETA FILTRADORA MEDIANTE ACCION CAPILAR AYUDADA POR UNA MATRIZ ABSORBENTE CON UN ALTO FACTOR DE KLEMM QUE SE APOYA EN LA TARJETA FILTRADORA. LA MATRIZ ABSORBENTE Y/O LA TARJETA FILTRADORA PUEDE TRATARSE CON UNA AMPLIA GAMA DE REACTIVOS DE ANALISIS. LA VELOCIDAD Y LA EFICIENCIA DEL PROCESO DE SEPARACION PUEDEALTERARSE MEDIANTE: (A) EL CAMBIO DE LA CONCENTRACION DE CARBOHIDRATO/PROTEINA EN LA MEZCLA; (B) LA APLICACION DE PRESION EN UN LADO DEL FILTRO; Y/O (C) VARIANDO LA DENSIDAD RELATIVA Y EL TAMAÑO DEL PORO DE LA TARJETA FILTRADORA Y DE LA MATRIZ ABSORBENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24718794A | 1994-05-19 | 1994-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2185704T3 true ES2185704T3 (es) | 2003-05-01 |
Family
ID=22933940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95918455T Expired - Lifetime ES2185704T3 (es) | 1994-05-19 | 1995-05-15 | Procedimiento y aparato para la recogida, almacenamiento y analisis en tiempo real de sangre y otros fluidos corporales. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5665238A (es) |
EP (1) | EP0760950B1 (es) |
AT (1) | ATE226726T1 (es) |
AU (1) | AU695988B2 (es) |
DE (1) | DE69528645T2 (es) |
ES (1) | ES2185704T3 (es) |
WO (1) | WO1995031720A1 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5866007A (en) * | 1994-05-19 | 1999-02-02 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Method and apparatus for the collection, storage, and real time analysis of blood and other bodily fluids |
GB9422504D0 (en) * | 1994-11-08 | 1995-01-04 | Robertson Patricia M B | Blood testing |
US5725774A (en) * | 1995-04-07 | 1998-03-10 | Lxn Corp. | Whole blood separation method and devices using the same |
FR2735702B1 (fr) * | 1995-06-22 | 1997-07-25 | Inst Textile De France | Dispositif de separation physico-chimique de constituants d'un fluide |
AUPO087196A0 (en) * | 1996-07-05 | 1996-08-01 | Belclan Pty. Limited | Blood separation module |
JP3685283B2 (ja) * | 1997-02-13 | 2005-08-17 | 富士写真フイルム株式会社 | 血漿採取具 |
EP1056381B1 (en) * | 1998-02-23 | 2004-06-02 | The Dallas Group Of America, Inc. | Fluid filter having a filter envelope formed of panels having decreasing permeabilities |
US6149579A (en) * | 1998-03-23 | 2000-11-21 | Lee; Won Ku | Semen storage container and its stopper |
IT1299176B1 (it) * | 1998-05-18 | 2000-02-29 | Ams S R L | Piastra-reattivo multiuso per analisi, in particolare per l'analisi diretta del sangue intero o di fluidi contenenti particelle o |
US6036659A (en) * | 1998-10-09 | 2000-03-14 | Flexsite Diagnostics, Inc. | Collection device for biological samples and methods of use |
JP4638986B2 (ja) | 1998-10-16 | 2011-02-23 | テルモ メディカル コーポレイション | 血液処理装置 |
US6398956B1 (en) | 1999-05-28 | 2002-06-04 | Bio/Data Corporation | Method and apparatus for directly sampling a fluid for microfiltration |
US7288195B2 (en) * | 1999-05-28 | 2007-10-30 | Bio/Data Corporation | Method and apparatus for directly sampling a fluid for microfiltration |
US6696240B1 (en) | 1999-10-26 | 2004-02-24 | Micronix, Inc. | Capillary test strip to separate particulates |
US6936473B2 (en) * | 2000-01-05 | 2005-08-30 | Leisure, Inc. | Method of preparing a biological sample for quantification |
EP1125591A1 (en) * | 2000-01-05 | 2001-08-22 | Maehata, Eisuke | Instrument and method for blood separation |
US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
JP4191051B2 (ja) * | 2002-02-27 | 2008-12-03 | 三光純薬株式会社 | 血漿又は血清分離具 |
WO2006130299A2 (en) * | 2005-05-03 | 2006-12-07 | Micronics, Inc. | Microfluidic laminar flow detection strip |
US9575084B1 (en) * | 2010-08-25 | 2017-02-21 | Thomas W. Astle | Dried specimen storage slide |
US9546935B1 (en) * | 2010-08-25 | 2017-01-17 | Thomas W. Astle | Dried specimen storage slides, systems and methods |
AU2012327218C1 (en) | 2011-11-30 | 2015-12-24 | Wellstat Diagnostics, Llc. | Filtration Module |
US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
CN106955749B (zh) * | 2017-03-19 | 2019-05-14 | 北京化工大学 | 基于微流控芯片的血浆提取装置 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3146163A (en) * | 1962-01-23 | 1964-08-25 | John H Brewer | Apparatus for separating certain components from blood |
CA1056746A (en) * | 1974-09-06 | 1979-06-19 | Chung J. Lai | Biologically active membrane material |
US4816224A (en) * | 1980-08-05 | 1989-03-28 | Boehringer Mannheim Gmbh | Device for separating plasma or serum from whole blood and analyzing the same |
JPS6138608A (ja) * | 1984-07-31 | 1986-02-24 | Fuji Photo Film Co Ltd | 全血からの血漿の分離器具および分離方法 |
US4678757A (en) * | 1985-04-11 | 1987-07-07 | Smithkline Diagnostics, Inc. | Device and method for whole blood separation and analysis |
US4829009A (en) * | 1986-02-21 | 1989-05-09 | The Regents Of The University Of California | Noise controlled immunoassays |
US5135719A (en) * | 1986-10-29 | 1992-08-04 | Biotrack, Inc. | Blood separation device comprising a filter and a capillary flow pathway exiting the filter |
DE3889479T2 (de) * | 1987-02-27 | 1994-12-22 | Eastman Kodak Co | Mit Nieder-pI-Protein beschichtete Membranstruktur und Verfahren zu ihrer Herstellung und Verwendung. |
AU626794B2 (en) * | 1987-06-05 | 1992-08-13 | National Diagnostic Products (Australia) Pty. Limited | Improvements in diagnostic test strips |
US4987085A (en) * | 1987-06-22 | 1991-01-22 | Chemtrak Inc. | Blood filtering metering device |
US4826009A (en) * | 1987-08-18 | 1989-05-02 | The Kendall Company | Container assembly |
NL8800796A (nl) * | 1988-03-29 | 1989-10-16 | X Flow Bv | Werkwijze voor de chemische analyse van bestanddelen van een lichaamsvloeistof, alsmede een testinrichting en testpakket voor een dergelijke analyse. |
US5423989A (en) * | 1988-05-19 | 1995-06-13 | Chemtrack, Inc. | Plasma forming device |
US5340539A (en) * | 1989-03-16 | 1994-08-23 | Chemtrak, Inc. | Non-instrumented cholesterol assay |
US4933092A (en) * | 1989-04-07 | 1990-06-12 | Abbott Laboratories | Methods and devices for the separation of plasma or serum from whole blood |
DE3929032C2 (de) * | 1989-09-01 | 1998-09-03 | Boehringer Mannheim Gmbh | Verfahren zur Bestimmung von HDL-Cholesterin mittels eines Schnelldiagnostikums mit integriertem Fraktionierschritt |
DE4015589A1 (de) * | 1990-05-15 | 1991-11-21 | Boehringer Mannheim Gmbh | Vorrichtung und deren verwendung zur abtrennung von plasma aus vollblut |
US5207984A (en) * | 1991-03-11 | 1993-05-04 | Miles Inc. | Blood sample collection and test device |
US5139685A (en) * | 1991-03-26 | 1992-08-18 | Gds Technology, Inc. | Blood separation filter assembly and method |
JPH05188053A (ja) * | 1992-01-10 | 1993-07-27 | Sanwa Kagaku Kenkyusho Co Ltd | 血液から血清又は血漿成分を分離する器具 |
US5460777A (en) * | 1992-03-16 | 1995-10-24 | Fuji Photo Film Co., Ltd. | Analytical element for whole blood analysis |
US5460974A (en) * | 1992-10-13 | 1995-10-24 | Miles Inc. | Method of assaying whole blood for HDL cholesterol |
-
1995
- 1995-05-15 WO PCT/AU1995/000279 patent/WO1995031720A1/en active IP Right Grant
- 1995-05-15 ES ES95918455T patent/ES2185704T3/es not_active Expired - Lifetime
- 1995-05-15 AU AU24393/95A patent/AU695988B2/en not_active Ceased
- 1995-05-15 DE DE69528645T patent/DE69528645T2/de not_active Expired - Fee Related
- 1995-05-15 EP EP95918455A patent/EP0760950B1/en not_active Expired - Lifetime
- 1995-05-15 AT AT95918455T patent/ATE226726T1/de not_active IP Right Cessation
-
1996
- 1996-01-26 US US08/605,300 patent/US5665238A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU695988B2 (en) | 1998-08-27 |
DE69528645D1 (de) | 2002-11-28 |
MX9605601A (es) | 1998-05-31 |
DE69528645T2 (de) | 2003-06-18 |
US5665238A (en) | 1997-09-09 |
AU2439395A (en) | 1995-12-05 |
EP0760950A4 (en) | 1997-07-16 |
WO1995031720A1 (en) | 1995-11-23 |
EP0760950B1 (en) | 2002-10-23 |
ATE226726T1 (de) | 2002-11-15 |
EP0760950A1 (en) | 1997-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2185704T3 (es) | Procedimiento y aparato para la recogida, almacenamiento y analisis en tiempo real de sangre y otros fluidos corporales. | |
KR910016365A (ko) | 전혈(全血)로부터 혈장 또는 혈청의 분리 및 수집을 위한 방법 및 장치, 및 시약 전달 시스템 | |
DE69636389D1 (de) | Vorrichtungen und verfahren zur abtrennung zellulärer blutkomponenten von flüssigen blutanteilen | |
Regezi et al. | Lichen planus: immunologic and morphologic identification of the submucosal infiltrate | |
ATE255956T1 (de) | Trennung und sammlung von analytenmaterial | |
ES530904A0 (es) | Procedimiento para la separacion extracorporal selectiva de precipitados de especies macromoleculares patologicas y-o toxicas | |
Stein et al. | Surface immunoglobulins and lymphocyte-specific surface antigens on leukaemic reticuloendotheliosis cells | |
EP0290921A3 (en) | Test-piece for the analysis of a liquid sample and method for its preparation | |
FR2459479B1 (fr) | Procede de separation d'une substance proteinique a partir d'une solution la contenant par filtration d'affinite et application dudit procede aux dosages enzymatiques | |
SE8600019D0 (sv) | Suspension liquid separator | |
JPS6421362A (en) | Method and apparatus for separating and testing whole blood | |
Franke et al. | Plakoglobin is a component of the filamentous subplasmalemmal coat of lens cells | |
Clement et al. | New concepts about hair identification revealed by electron microscope studies | |
GB1392304A (en) | Method for blood sample analysis | |
CA2111350A1 (en) | Method for the separation of high density lipoprotein from blood samples | |
ES2053669T3 (es) | Agente para diagnostico y procedimiento para la determinacion de apolipoproteina b. | |
AU7379687A (en) | A process for obtaining active proteins from a biologically inactive form | |
ES8501630A1 (es) | Un metodo para detectar o vigilar el estado de una condicion patologica humana que implica proteina de tejido conjuntivo. | |
Otani et al. | Leukocyte chemotaxis: a new in vivo testing technique | |
ES2110998T3 (es) | Procedimiento para la determinacion de las trombopenias. | |
ES2045952T3 (es) | Producto espumoso para el te\ido del cabello. | |
Fischl et al. | Investigation of protein fractions and haemolytic properties of wasp venom | |
Friedman et al. | Inhibition of protein synthesis by an extract of the venom sac of the oriental hornet (Vespa orientalis) | |
RU2139536C1 (ru) | Способ фиксации и концентрации клеток в электронной микроскопии | |
Teital et al. | Physicochemical Investigations of Erythrocyte Membranes |