CA2737025C - Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof - Google Patents
Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof Download PDFInfo
- Publication number
- CA2737025C CA2737025C CA2737025A CA2737025A CA2737025C CA 2737025 C CA2737025 C CA 2737025C CA 2737025 A CA2737025 A CA 2737025A CA 2737025 A CA2737025 A CA 2737025A CA 2737025 C CA2737025 C CA 2737025C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- oil
- cholesterol
- acid
- finasteride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Birds (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10071408P | 2008-09-27 | 2008-09-27 | |
| US61/100,714 | 2008-09-27 | ||
| PCT/US2009/058463 WO2010036947A2 (en) | 2008-09-27 | 2009-09-25 | Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2737025A1 CA2737025A1 (en) | 2010-04-01 |
| CA2737025C true CA2737025C (en) | 2012-09-04 |
Family
ID=42060413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2737025A Active CA2737025C (en) | 2008-09-27 | 2009-09-25 | Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9750812B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2344198B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2012504135A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2737025C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1123579T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2344198T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2834006T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20201860T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE052571T2 (cg-RX-API-DMAC7.html) |
| LT (1) | LT2344198T (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011003207A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2344198T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2344198T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2344198T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010036947A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180038574A (ko) | 2008-07-18 | 2018-04-16 | 바이오모드 컨셉츠 인코포레이티드 | 활성 성분을 방출하는 제품 |
| US9588118B2 (en) | 2010-09-24 | 2017-03-07 | Follea International | Devices for performing colorimetric assay with plucked human hair |
| US8691518B2 (en) | 2010-09-24 | 2014-04-08 | Global Life Science Partners Limited | Systems and methods for predicting response to minoxidil for the treatment of androgenetic alopecia |
| US10633688B2 (en) | 2010-09-24 | 2020-04-28 | Follea International | Systems and methods for predicting response to minoxidil for the treatment of androgenetic alopecia |
| ITMI20102165A1 (it) * | 2010-11-23 | 2012-05-24 | Medichem Srl | Composizione per il lavaggio dei capelli e del cuoio capelluto |
| PL2702982T3 (pl) * | 2011-04-25 | 2017-07-31 | Jun-Hyoung Park | Kompozycja do miejscowego stosowania do zapobiegania wypadaniu włosów i stymulowania porostu włosów |
| JP2015514683A (ja) * | 2012-02-16 | 2015-05-21 | ブライトサイド イノベーションズ,インコーポレイティド | 食品性栄養組成物および使用方法 |
| EP2844265A4 (en) * | 2012-04-25 | 2016-01-06 | Hadasit Med Res Service | POMEGRANATE OIL FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES |
| BR102012022036B1 (pt) * | 2012-08-31 | 2019-10-01 | Biolab Sanus Farmacêutica Ltda. | Nanopartícula polimérica de finasterida e minoxidil, processo de sua preparação, suspensão aquosa contendo a mesma, composição farmacêutica, e seu uso |
| BR102012022034B1 (pt) * | 2012-08-31 | 2020-02-18 | Biolab Sanus Farmacêutica Ltda. | Nanopartícula polimérica de finasterida, suspensão aquosa contendo a mesma, composição para tratamento de alopecia, processo de preparação de dita composição, e seu uso |
| US20150313829A1 (en) * | 2012-11-26 | 2015-11-05 | Roberto Queiroga Lautner | Topical formulations for the prevention and treatment of alopecia and inhibition of hair growth |
| JP6595454B2 (ja) * | 2013-05-03 | 2019-10-23 | リピドール エービー | 薬学的又は化粧学的活性成分を投与するための局部用組成物及びキャリアー |
| KR102157407B1 (ko) | 2013-08-15 | 2020-09-17 | 마리 케이 인코포레이티드 | 주름 치료를 위한 국소 피부 조성물 |
| US20150147382A1 (en) * | 2013-09-23 | 2015-05-28 | Exir Nano Sina Company | Topical liposomal compositions for delivering hydrophobic drugs and methods preparing same |
| US11660344B2 (en) | 2013-11-17 | 2023-05-30 | Medrx Co., Ltd. | Transdermal colloidal solution agent |
| CN105722502A (zh) * | 2013-11-17 | 2016-06-29 | 株式会社梅德瑞科思 | 经皮吸收胶体型液体制剂 |
| KR20240011239A (ko) | 2014-10-29 | 2024-01-25 | 삼손 클리니컬 피티와이 엘티디 | 과도한 모발 쉐딩의 검출 및 치료 |
| EP3038053B1 (en) | 2014-12-22 | 2019-11-06 | Reactive Reality GmbH | Method and system for generating garment model data |
| EP3283045B1 (en) * | 2015-04-13 | 2021-02-17 | Fountain Technologies International, LLC | One-step method for production of ultra-small lipid structures |
| EP3299012A4 (en) * | 2015-05-19 | 2018-12-26 | MEDRx Co., Ltd. | Transdermal liquid preparation |
| SG10202010303UA (en) * | 2016-04-19 | 2020-11-27 | Univ Nanyang Tech | Nanoliposomes for sustained delivery of tacrolimus for treatment of anterior segment eye diseases |
| CA3041592C (en) | 2016-10-28 | 2023-01-17 | Les Laboratoires Servier | Liposomal formulation for use in the treatment of cancer |
| GB2600652B (en) * | 2017-05-30 | 2022-11-02 | Glaxosmithkline Biologicals Sa | Novel compositions |
| WO2019010535A1 (en) * | 2017-07-12 | 2019-01-17 | Samson Clinical Pty Ltd | STIMULATION OF HAIR GROWTH AND TREATMENT OF HAIR FALL OR EXCESSIVE ALOPECIA |
| JP2021508334A (ja) * | 2017-10-27 | 2021-03-04 | トピルクス セラピューティクス インコーポレイテッド | 男性型禿頭症を含む皮膚障害を処置するための局所製剤 |
| MX390288B (es) | 2018-02-06 | 2025-03-20 | Centro Int De Cosmiatria S A P I De C V | Formulación y método para el tratamiento de la alopecia androgénica. |
| JP2022506944A (ja) * | 2018-11-08 | 2022-01-17 | ヴァーソナ セラピューティクス,インコーポレーテッド | 5-α-レダクターゼ阻害剤の局所製剤及びそれらの使用 |
| WO2020109365A1 (en) * | 2018-11-29 | 2020-06-04 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
| WO2021232054A1 (en) * | 2020-05-12 | 2021-11-18 | Chemistryrx | Compositions for treating hair loss |
| US11311556B2 (en) | 2020-05-13 | 2022-04-26 | Varsona Therapeutics, Inc. | Topical dutasteride emulsions for treating endocrine therapy-induced alopecia |
| US11850300B2 (en) | 2022-03-17 | 2023-12-26 | Rally Guide | Topical lotion composition, methods of use, and methods of preparation |
| WO2024213102A1 (en) * | 2023-04-14 | 2024-10-17 | Beijing Jitai Pharmaceutical Technology Co., Ltd. | Lipid nanoparticle compositions and uses thereof |
| WO2025037276A1 (en) * | 2023-08-16 | 2025-02-20 | Jina Pharmaceuticals Inc. | COMPOSITIONS CONTAINING mTOR INHIBITORS AND LIPIDS |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3585967D1 (de) * | 1984-03-08 | 1992-06-11 | Phares Pharma Holland | Liposombildende zusammensetzung. |
| US4663167A (en) * | 1984-04-16 | 1987-05-05 | The Board Of Regents Of The University Of Texas System | Composition and method for treatment of disseminated fungal infections in mammals |
| DE3576117D1 (de) | 1984-09-24 | 1990-04-05 | Michael Mezei | Mehrphasige pharmazeutische zusammensetzung. |
| US4897269A (en) * | 1984-09-24 | 1990-01-30 | Mezei Associates Limited | Administration of drugs with multiphase liposomal delivery system |
| US4761288A (en) * | 1984-09-24 | 1988-08-02 | Mezei Associates Limited | Multiphase liposomal drug delivery system |
| US5616334A (en) * | 1987-03-05 | 1997-04-01 | The Liposome Company, Inc. | Low toxicity drug-lipid systems |
| US6406713B1 (en) * | 1987-03-05 | 2002-06-18 | The Liposome Company, Inc. | Methods of preparing low-toxicity drug-lipid complexes |
| US5030442A (en) * | 1987-03-30 | 1991-07-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition |
| US4828837A (en) * | 1987-03-30 | 1989-05-09 | Liposome Technology, Inc. | Non-crystalline minoxidil composition, its production and application |
| DE3888994T2 (de) | 1987-04-03 | 1994-11-03 | Merck & Co Inc | Behandlung von androgener Alopecia mit 17-beta-n-mono-substituierten-carbamoyl-4-aza-5-alpha-androst-1-en-3-onen. |
| WO1989005636A1 (en) * | 1987-12-22 | 1989-06-29 | The Liposome Company, Inc. | Spontaneous vesiculation of multilamellar liposomes |
| US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
| HU208070B (en) | 1989-03-31 | 1993-08-30 | Univ California | Process for producing lipid suspension |
| WO1992003123A1 (en) | 1990-08-28 | 1992-03-05 | Liposome Technology, Inc. | Liposome alternative bilayer formulations |
| US20040175417A1 (en) * | 1990-10-19 | 2004-09-09 | Gilead Sciences, Inc. | Amphotericin B liposome preparation |
| GB9111611D0 (en) | 1991-05-30 | 1991-07-24 | Sandoz Ltd | Liposomes |
| US6733776B1 (en) * | 1992-04-02 | 2004-05-11 | Anticancer, Inc. | Method for promoting hair growth |
| US7556825B2 (en) * | 1993-04-02 | 2009-07-07 | Anticancer, Inc. | Method for promoting hair growth |
| US7083572B2 (en) * | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
| FI100692B (fi) * | 1994-05-24 | 1998-02-13 | Leiras Oy | Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä |
| US5540934A (en) * | 1994-06-22 | 1996-07-30 | Touitou; Elka | Compositions for applying active substances to or through the skin |
| US6001812A (en) * | 1995-04-28 | 1999-12-14 | Societe L'oreal S.A. | Modulating body/cranial hair growth with derivatives of the α-type melanocyte-stimulating hormone |
| JPH0971513A (ja) * | 1995-09-07 | 1997-03-18 | Taisho Pharmaceut Co Ltd | 育毛剤 |
| US5834014A (en) | 1995-10-06 | 1998-11-10 | The Regents Of The University Of Michigan | Stimulation of hair follicles |
| JP3596835B2 (ja) | 1996-08-13 | 2004-12-02 | 株式会社ノエビア | 養毛剤 |
| US6030948A (en) * | 1997-12-19 | 2000-02-29 | Mann; Morris A. | Hair regeneration compositions for treatment of alopecia and methods of application related thereto |
| US6265412B1 (en) | 1998-05-26 | 2001-07-24 | Taisho Pharmaceutical Co., Ltd. | Minoxidil compositions for external use |
| US6284234B1 (en) | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| JP4444385B2 (ja) * | 1999-02-25 | 2010-03-31 | 帝人株式会社 | リポソーム用時調製用キット |
| KR20010102370A (ko) * | 1999-03-11 | 2001-11-15 | 후지야마 아키라 | 리포좀 제제 |
| CA2309373A1 (en) * | 1999-05-27 | 2000-11-27 | Johnson & Johnson Consumer Companies, Inc. | Novel topical formulations |
| US6596266B2 (en) * | 2000-02-18 | 2003-07-22 | Natural Science, Inc. | Compositions containing minoxidil and saw palmetto for treating baldness |
| JP4780429B2 (ja) * | 2000-04-07 | 2011-09-28 | 大正製薬株式会社 | ミノキシジル含有製剤 |
| MXPA02010866A (es) | 2000-05-05 | 2003-07-14 | Wisconsin Alumni Res Found | Composiciones y metodos para proteger celulas durante la quimioterapia y radioterapia contra el cancer. |
| IN188843B (cg-RX-API-DMAC7.html) * | 2000-06-22 | 2002-11-09 | Vinod Daftary Gautam Dr | |
| EP1313479A4 (en) | 2000-07-19 | 2005-09-21 | W Roy Knowles | PREVENTION OF HAIR LOSS |
| DE10036799A1 (de) * | 2000-07-28 | 2002-02-07 | Beiersdorf Ag | Neues Mittel zur Behandlung der Haare und der Kopfhaut |
| SE0100374D0 (sv) * | 2001-02-07 | 2001-02-07 | Pharmacia Ab | Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof |
| ATE440593T1 (de) * | 2001-03-27 | 2009-09-15 | Phares Pharm Res Nv | Verfahren und zusammensetzung zur solubilisierung einer biologisch wirksamen verbindung mit geringer wasserlíslichkeit |
| JP4796260B2 (ja) * | 2001-04-05 | 2011-10-19 | 大正製薬株式会社 | ミノキシジル含有製剤 |
| US7045550B2 (en) * | 2001-08-07 | 2006-05-16 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
| US6656460B2 (en) | 2001-11-01 | 2003-12-02 | Yissum Research Development | Method and composition for dry eye treatment |
| US20050232984A1 (en) * | 2002-08-23 | 2005-10-20 | Heinrich Haas | Non-vesicular cationic lipid formulations |
| WO2004030677A1 (en) * | 2002-10-03 | 2004-04-15 | University Of Mississippi | Compositions comprising highly purified amphotericin b |
| JP2006510733A (ja) * | 2002-10-16 | 2006-03-30 | ネオファーム、インコーポレイティッド | カルジオリピン分子および合成方法 |
| JP2004155690A (ja) * | 2002-11-05 | 2004-06-03 | Shiseido Co Ltd | 養毛剤組成物 |
| US20040121003A1 (en) | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| WO2005000266A2 (en) | 2003-05-22 | 2005-01-06 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
| KR100508019B1 (ko) * | 2003-07-19 | 2005-08-17 | 한미약품 주식회사 | 고순도 1-안드로스텐 유도체의 제조 방법 |
| ITMI20032019A1 (it) * | 2003-10-17 | 2005-04-18 | Fidia Farmaceutici | Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono |
| EP1755623A4 (en) * | 2004-05-21 | 2007-10-17 | Transave Inc | TREATMENT OF LUNG DISEASES AND BEFORE A PULMONARY DISEASE |
| AU2005279878A1 (en) * | 2004-08-30 | 2006-03-09 | Theregen, Inc. | Conditioned medium comprising Wnt proteins to promote repair of damaged tissue |
| EP1804751A2 (en) | 2004-10-04 | 2007-07-11 | QLT USA, Inc. | Ocular delivery of polymeric delivery formulations |
| CN101309698A (zh) * | 2005-03-30 | 2008-11-19 | 惠氏公司 | 通过施用bmp来刺激毛发生长的方法 |
| JP2006290841A (ja) * | 2005-04-14 | 2006-10-26 | Nippon Zettoc Co Ltd | 化粧料の製造方法および化粧料 |
| DE102005026755A1 (de) * | 2005-06-09 | 2006-12-14 | Basf Ag | Herstellung von festen Lösungen schwerlöslicher Wirkstoffe durch Kurzzeitüberhitzung und schnelle Trocknung |
| WO2008038140A2 (en) * | 2006-06-07 | 2008-04-03 | Foamix Ltd. | Foamable vehicle comprising polypropylene glycol alkyl ether and pharmaceutical compositions thereof |
| PT2076244T (pt) | 2006-10-10 | 2017-03-09 | Jina Pharmaceuticals Inc | Sistemas aquosos para a preparação de compostos farmacêuticos à base de lípidos; composições, métodos e utilizações dos mesmos |
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| CN101559038B (zh) | 2009-05-21 | 2011-03-16 | 江苏黄河药业股份有限公司 | 非那雄胺的固体脂质纳米粒及其制备方法 |
-
2009
- 2009-09-25 MX MX2011003207A patent/MX2011003207A/es active IP Right Grant
- 2009-09-25 PT PT98169402T patent/PT2344198T/pt unknown
- 2009-09-25 LT LTEP09816940.2T patent/LT2344198T/lt unknown
- 2009-09-25 WO PCT/US2009/058463 patent/WO2010036947A2/en not_active Ceased
- 2009-09-25 PL PL09816940T patent/PL2344198T3/pl unknown
- 2009-09-25 SI SI200932098T patent/SI2344198T1/sl unknown
- 2009-09-25 US US13/120,127 patent/US9750812B2/en active Active
- 2009-09-25 HU HUE09816940A patent/HUE052571T2/hu unknown
- 2009-09-25 DK DK09816940.2T patent/DK2344198T3/da active
- 2009-09-25 ES ES09816940T patent/ES2834006T3/es active Active
- 2009-09-25 CA CA2737025A patent/CA2737025C/en active Active
- 2009-09-25 HR HRP20201860TT patent/HRP20201860T1/hr unknown
- 2009-09-25 JP JP2011529277A patent/JP2012504135A/ja active Pending
- 2009-09-25 EP EP09816940.2A patent/EP2344198B1/en active Active
-
2014
- 2014-06-25 JP JP2014130194A patent/JP6196943B2/ja active Active
-
2016
- 2016-09-09 JP JP2016176561A patent/JP2017048188A/ja active Pending
-
2020
- 2020-11-26 CY CY20201101126T patent/CY1123579T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1123579T1 (el) | 2022-03-24 |
| WO2010036947A2 (en) | 2010-04-01 |
| EP2344198A4 (en) | 2013-01-09 |
| JP2012504135A (ja) | 2012-02-16 |
| LT2344198T (lt) | 2021-02-25 |
| CA2737025A1 (en) | 2010-04-01 |
| JP2017048188A (ja) | 2017-03-09 |
| US20110212167A1 (en) | 2011-09-01 |
| PL2344198T3 (pl) | 2021-05-31 |
| SI2344198T1 (sl) | 2021-01-29 |
| ES2834006T3 (es) | 2021-06-16 |
| WO2010036947A3 (en) | 2010-06-10 |
| US9750812B2 (en) | 2017-09-05 |
| HRP20201860T1 (hr) | 2021-04-16 |
| DK2344198T3 (da) | 2020-11-30 |
| EP2344198B1 (en) | 2020-11-04 |
| JP6196943B2 (ja) | 2017-09-13 |
| EP2344198A2 (en) | 2011-07-20 |
| HUE052571T2 (hu) | 2021-05-28 |
| MX2011003207A (es) | 2011-11-04 |
| JP2014221784A (ja) | 2014-11-27 |
| PT2344198T (pt) | 2020-12-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2737025C (en) | Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof | |
| JP6901421B2 (ja) | 半フッ化アルカンを基礎にした局所薬学的組成物 | |
| JP3903061B2 (ja) | 薬物を含有するナノ粒子およびその製造方法、ならびに当該ナノ粒子からなる非経口投与用製剤 | |
| AU2013371101B2 (en) | Sustained-release lipid pre-concentrate of GnRH analogues and pharmaceutical composition comprising the same | |
| CN104427977B (zh) | 局部麻醉剂的储库制剂及其制备方法 | |
| EP3845247B1 (en) | Use of amino acid based nutrients and pharmaceutical composition containing the same | |
| JP2002533379A (ja) | 生体内における局所的に非侵襲性である用途のための改善された製剤 | |
| US20110135714A1 (en) | Compositions for external application, containing adenosyl cobalamin for improvement of skin diseases | |
| TW201124425A (en) | Parenteral formulations of gemcitabine derivatives | |
| JP2006524659A (ja) | ケラチノサイトの過剰増殖、特に、アトピー性皮膚炎および乾癬を特徴とする疾患を治療するためのリルゾールの使用 | |
| JPS63301824A (ja) | 極性および中性脂質混合物を含有する胃腸管保護用組成物および胃腸管保護方法 | |
| JP2001502676A (ja) | 障壁を通して活性成分を輸送するための調製物 | |
| CN102470104B (zh) | 含有dha酯的非胃肠道给药的药用组合物 | |
| CH673395A5 (cg-RX-API-DMAC7.html) | ||
| CN1213964A (zh) | 抗糖皮质激素药物 | |
| JP2937135B2 (ja) | Pge1含有凍結乾燥製剤及び製法 | |
| EP2931250A1 (en) | Gel compositions | |
| JP2514995B2 (ja) | 経皮、経粘膜による物質の吸収を促進する組成物 | |
| WO2012122493A1 (en) | Lipid based clopidogrel compositions, methods, and uses | |
| JPH05501714A (ja) | リポソーム組成物 | |
| JPH04360832A (ja) | リポソーム製剤 | |
| JPWO1998030221A1 (ja) | 点眼用ジフルプレドナート含有o/wエマルジョン組成物 | |
| CN1179721A (zh) | 新型药物制剂 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |