CA2683461A1 - Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals - Google Patents

Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals Download PDF

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Publication number
CA2683461A1
CA2683461A1 CA002683461A CA2683461A CA2683461A1 CA 2683461 A1 CA2683461 A1 CA 2683461A1 CA 002683461 A CA002683461 A CA 002683461A CA 2683461 A CA2683461 A CA 2683461A CA 2683461 A1 CA2683461 A1 CA 2683461A1
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Canada
Prior art keywords
butyl
group
denotes
case
tert
Prior art date
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Abandoned
Application number
CA002683461A
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English (en)
French (fr)
Inventor
Robert Frank
Gregor Bahrenberg
Thomas Christoph
Klaus Schiene
Jean De Vry
Derek John Saunders
Bernd Sundermann
Jeewoo Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal Gmbh
Robert Frank
Gregor Bahrenberg
Thomas Christoph
Klaus Schiene
Jean De Vry
Derek John Saunders
Bernd Sundermann
Jeewoo Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102007018149A external-priority patent/DE102007018149A1/de
Application filed by Gruenenthal Gmbh, Robert Frank, Gregor Bahrenberg, Thomas Christoph, Klaus Schiene, Jean De Vry, Derek John Saunders, Bernd Sundermann, Jeewoo Lee filed Critical Gruenenthal Gmbh
Publication of CA2683461A1 publication Critical patent/CA2683461A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
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CA002683461A 2007-04-16 2008-04-16 Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals Abandoned CA2683461A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DE102007018149.5 2007-04-16
DE102007018149A DE102007018149A1 (de) 2007-04-16 2007-04-16 Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
US12/103,667 2008-04-15
US12/103,667 US8084484B2 (en) 2007-04-16 2008-04-15 Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
EPPCT/EP2008/002997 2008-04-15
EP2008002997 2008-04-15
PCT/EP2008/003027 WO2008125342A2 (de) 2007-04-16 2008-04-16 Vanilloid-rezeptor-liganden und ihre verwendung zur herstellung von arzneimitteln

Publications (1)

Publication Number Publication Date
CA2683461A1 true CA2683461A1 (en) 2008-10-23

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CA002683461A Abandoned CA2683461A1 (en) 2007-04-16 2008-04-16 Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals

Country Status (14)

Country Link
JP (1) JP2010523727A (ko)
KR (1) KR20100016593A (ko)
CN (1) CN101679370A (ko)
AU (1) AU2008238250B2 (ko)
BR (1) BRPI0810035A2 (ko)
CA (1) CA2683461A1 (ko)
CO (1) CO6241154A2 (ko)
EC (1) ECSP099692A (ko)
IL (1) IL201505A0 (ko)
MX (1) MX2009011149A (ko)
NZ (1) NZ580411A (ko)
RU (1) RU2498982C2 (ko)
WO (1) WO2008125342A2 (ko)
ZA (1) ZA200907099B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10351535B2 (en) 2013-12-20 2019-07-16 Esteve Pharmaceuticals, S.A. Piperazine derivatives having multimodal activity against pain

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007018149A1 (de) 2007-04-16 2008-10-23 Grünenthal GmbH Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
MX2011011797A (es) 2009-05-07 2011-11-29 Gruenenthal Gmbh Fenilureas y fenilamidas sustituidas como ligandos del receptor de vanilloides.
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JP2010523727A (ja) 2010-07-15
RU2498982C2 (ru) 2013-11-20
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IL201505A0 (en) 2010-05-31
BRPI0810035A2 (pt) 2016-07-26
AU2008238250A1 (en) 2008-10-23
WO2008125342A3 (de) 2009-01-15
ZA200907099B (en) 2013-03-27
ECSP099692A (es) 2009-11-30
WO2008125342A2 (de) 2008-10-23
CN101679370A (zh) 2010-03-24
AU2008238250B2 (en) 2013-01-24

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