ECSP099692A - Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticas - Google Patents
Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticasInfo
- Publication number
- ECSP099692A ECSP099692A EC2009009692A ECSP099692A ECSP099692A EC SP099692 A ECSP099692 A EC SP099692A EC 2009009692 A EC2009009692 A EC 2009009692A EC SP099692 A ECSP099692 A EC SP099692A EC SP099692 A ECSP099692 A EC SP099692A
- Authority
- EC
- Ecuador
- Prior art keywords
- production
- pharmaceutical substances
- vinylloid
- new
- receiver links
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
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- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
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Abstract
La presente invención se relaciona con ligandos de receptor vainilloide novedosos, un método para la producción de los mismos, sustancias farmacéuticas que contienen dichos compuestos y el uso de tales compuestos para la producción de sustancias farmacéuticas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007018149A DE102007018149A1 (de) | 2007-04-16 | 2007-04-16 | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US12/103,667 US8084484B2 (en) | 2007-04-16 | 2008-04-15 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions |
EP2008002997 | 2008-04-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099692A true ECSP099692A (es) | 2009-11-30 |
Family
ID=41360190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009692A ECSP099692A (es) | 2007-04-16 | 2009-10-16 | Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticas |
Country Status (14)
Country | Link |
---|---|
JP (1) | JP2010523727A (es) |
KR (1) | KR20100016593A (es) |
CN (1) | CN101679370A (es) |
AU (1) | AU2008238250B2 (es) |
BR (1) | BRPI0810035A2 (es) |
CA (1) | CA2683461A1 (es) |
CO (1) | CO6241154A2 (es) |
EC (1) | ECSP099692A (es) |
IL (1) | IL201505A0 (es) |
MX (1) | MX2009011149A (es) |
NZ (1) | NZ580411A (es) |
RU (1) | RU2498982C2 (es) |
WO (1) | WO2008125342A2 (es) |
ZA (1) | ZA200907099B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007018149A1 (de) | 2007-04-16 | 2008-10-23 | Grünenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US8946204B2 (en) | 2009-05-07 | 2015-02-03 | Gruenenthal Gmbh | Substituted phenylureas and phenylamides as vanilloid receptor ligands |
WO2010127856A1 (en) * | 2009-05-07 | 2010-11-11 | Grünenthal GmbH | Substituted phenyllureas and phenylamides as vanilloid receptor ligands |
KR20140049027A (ko) | 2011-07-26 | 2014-04-24 | 그뤼넨탈 게엠베하 | 치환된 헤테로사이클릭 아자 유도체 |
AU2012289254A1 (en) | 2011-07-26 | 2014-03-13 | Grünenthal GmbH | Substituted bicyclic aromatic carboxamide and urea derivatives as vanilloid receptor ligands |
AU2012334066A1 (en) * | 2011-11-09 | 2014-05-22 | Grunenthal Gmbh | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an N-containing group as vanilloid receptor ligands |
KR101773331B1 (ko) * | 2012-03-05 | 2017-08-31 | 닥터 레디스 레보러터리즈 리미티드 | 카파 오피오이드 수용체(κor) 작용제인 치환된 헤테로시클릭 아세트아미드 |
MX2016008130A (es) | 2013-12-20 | 2016-10-13 | Esteve Labor Dr | Derivados de piperidina con actividad multimodal contra el dolor. |
CN107721919B (zh) * | 2017-10-30 | 2020-12-08 | 中国药科大学 | 苯基喹啉类trpv1拮抗剂及其制备方法和应用 |
KR102334947B1 (ko) * | 2020-04-22 | 2021-12-06 | 주식회사 제이맥켐 | Trpv1 길항제로서 벤즈이미다졸론계 시남아마이드 유도체 및 이를 유효성분으로 함유하는 통증의 치료 또는 예방용 약학적 조성물 |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
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AU2002352868A1 (en) * | 2001-11-27 | 2003-06-10 | Merck & Co., Inc. | 4-aminoquinoline compounds |
MXPA04008073A (es) * | 2002-02-20 | 2004-11-26 | Abbott Lab | Compuestos azabiciclicos fusionados que inhiben el receptor de subtipo 1 (vr1) del receptor de vainilloide. |
GB0206876D0 (en) * | 2002-03-22 | 2002-05-01 | Merck Sharp & Dohme | Therapeutic agents |
US6933311B2 (en) * | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US20060211774A1 (en) * | 2003-04-29 | 2006-09-21 | Bennett Simon T | Method of diagnosins a genetic susceptibility for bone damage |
SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
MXPA05013434A (es) * | 2003-06-12 | 2006-03-17 | Astellas Pharma Inc | Derivados de benzamida o sal del mismo. |
US20050113576A1 (en) * | 2003-08-05 | 2005-05-26 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
JP2007523888A (ja) * | 2003-11-08 | 2007-08-23 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | テトラヒドロ−キノリニル尿素誘導体 |
WO2005073193A1 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
DE102005023943A1 (de) * | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Pentafluorsulfanyl-substituierte Verbindung und deren Verwendung zur Herstellung von Arzneimitteln |
CN101395147B (zh) * | 2005-12-28 | 2013-05-29 | 弗特克斯药品有限公司 | 作为atp-结合盒转运蛋白调节剂用于治疗囊性纤维化的1-(苯并[d][1,3]间二氧杂环戊烯-5-基)-n-(苯基)环丙烷-甲酰胺衍生物及相关化合物 |
-
2008
- 2008-04-16 CN CN200880020483A patent/CN101679370A/zh active Pending
- 2008-04-16 NZ NZ580411A patent/NZ580411A/en not_active IP Right Cessation
- 2008-04-16 WO PCT/EP2008/003027 patent/WO2008125342A2/de active Application Filing
- 2008-04-16 JP JP2010503397A patent/JP2010523727A/ja not_active Ceased
- 2008-04-16 RU RU2009142023/04A patent/RU2498982C2/ru not_active IP Right Cessation
- 2008-04-16 KR KR1020097023887A patent/KR20100016593A/ko not_active Application Discontinuation
- 2008-04-16 CA CA002683461A patent/CA2683461A1/en not_active Abandoned
- 2008-04-16 AU AU2008238250A patent/AU2008238250B2/en not_active Ceased
- 2008-04-16 MX MX2009011149A patent/MX2009011149A/es active IP Right Grant
- 2008-04-16 BR BRPI0810035A patent/BRPI0810035A2/pt not_active IP Right Cessation
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2009
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WO2008125342A3 (de) | 2009-01-15 |
ZA200907099B (en) | 2013-03-27 |
KR20100016593A (ko) | 2010-02-12 |
MX2009011149A (es) | 2009-10-30 |
RU2009142023A (ru) | 2011-05-27 |
RU2498982C2 (ru) | 2013-11-20 |
AU2008238250B2 (en) | 2013-01-24 |
CN101679370A (zh) | 2010-03-24 |
BRPI0810035A2 (pt) | 2016-07-26 |
IL201505A0 (en) | 2010-05-31 |
CO6241154A2 (es) | 2011-01-20 |
WO2008125342A2 (de) | 2008-10-23 |
AU2008238250A1 (en) | 2008-10-23 |
CA2683461A1 (en) | 2008-10-23 |
JP2010523727A (ja) | 2010-07-15 |
NZ580411A (en) | 2012-06-29 |
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