BRPI0810035A2 - ligantes de receptor de vaniloide e seu uso para produção de medicamento - Google Patents

ligantes de receptor de vaniloide e seu uso para produção de medicamento

Info

Publication number
BRPI0810035A2
BRPI0810035A2 BRPI0810035A BRPI0810035A BRPI0810035A2 BR PI0810035 A2 BRPI0810035 A2 BR PI0810035A2 BR PI0810035 A BRPI0810035 A BR PI0810035A BR PI0810035 A BRPI0810035 A BR PI0810035A BR PI0810035 A2 BRPI0810035 A2 BR PI0810035A2
Authority
BR
Brazil
Prior art keywords
receptor ligands
vanilloid receptor
drug production
drug
production
Prior art date
Application number
BRPI0810035A
Other languages
English (en)
Inventor
Bern Sundermann
Derek John Saunders
Gregor Bahrenberg
Jean De Vry
Jeewoo Lee
Klaus Schiene
Robert Frank
Thomas Christoph
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102007018149A external-priority patent/DE102007018149A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BRPI0810035A2 publication Critical patent/BRPI0810035A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
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    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
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    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
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    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
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    • C07D277/62—Benzothiazoles
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    • C07D277/82—Nitrogen atoms
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    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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BRPI0810035A 2007-04-16 2008-04-16 ligantes de receptor de vaniloide e seu uso para produção de medicamento BRPI0810035A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102007018149A DE102007018149A1 (de) 2007-04-16 2007-04-16 Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
US12/103,667 US8084484B2 (en) 2007-04-16 2008-04-15 Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
EP2008002997 2008-04-15
PCT/EP2008/003027 WO2008125342A2 (de) 2007-04-16 2008-04-16 Vanilloid-rezeptor-liganden und ihre verwendung zur herstellung von arzneimitteln

Publications (1)

Publication Number Publication Date
BRPI0810035A2 true BRPI0810035A2 (pt) 2016-07-26

Family

ID=41360190

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810035A BRPI0810035A2 (pt) 2007-04-16 2008-04-16 ligantes de receptor de vaniloide e seu uso para produção de medicamento

Country Status (14)

Country Link
JP (1) JP2010523727A (pt)
KR (1) KR20100016593A (pt)
CN (1) CN101679370A (pt)
AU (1) AU2008238250B2 (pt)
BR (1) BRPI0810035A2 (pt)
CA (1) CA2683461A1 (pt)
CO (1) CO6241154A2 (pt)
EC (1) ECSP099692A (pt)
IL (1) IL201505A0 (pt)
MX (1) MX2009011149A (pt)
NZ (1) NZ580411A (pt)
RU (1) RU2498982C2 (pt)
WO (1) WO2008125342A2 (pt)
ZA (1) ZA200907099B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007018149A1 (de) 2007-04-16 2008-10-23 Grünenthal GmbH Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
MX2011011797A (es) 2009-05-07 2011-11-29 Gruenenthal Gmbh Fenilureas y fenilamidas sustituidas como ligandos del receptor de vanilloides.
US8946204B2 (en) 2009-05-07 2015-02-03 Gruenenthal Gmbh Substituted phenylureas and phenylamides as vanilloid receptor ligands
MX2014000964A (es) 2011-07-26 2014-03-27 Gruenenthal Gmbh Derivados aza heterociclicos sustituidos.
BR112014001714A2 (pt) 2011-07-26 2017-02-14 Gruenenthal Gmbh derivados de carboxamida e ureia aromáticos bicíclicos substituídos como ligantes de receptor vaniloide
AR088701A1 (es) * 2011-11-09 2014-06-25 Gruenenthal Gmbh Derivados de carboxamida y urea basados en pirazolilo, sustituidos, que contienen una porcion fenilo sustituida con un grupo que contiene n como ligandos del receptor de vanilloide
AU2013230425B2 (en) * 2012-03-05 2017-05-25 Dr.Reddy's Laboratories Ltd. Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists
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