CA2680275C - Bicycloheteroaryl compounds as p2x7 modulators and uses thereof - Google Patents
Bicycloheteroaryl compounds as p2x7 modulators and uses thereof Download PDFInfo
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- CA2680275C CA2680275C CA2680275A CA2680275A CA2680275C CA 2680275 C CA2680275 C CA 2680275C CA 2680275 A CA2680275 A CA 2680275A CA 2680275 A CA2680275 A CA 2680275A CA 2680275 C CA2680275 C CA 2680275C
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Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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Landscapes
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Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90604907P | 2007-03-09 | 2007-03-09 | |
| US60/906,049 | 2007-03-09 | ||
| US91826107P | 2007-03-15 | 2007-03-15 | |
| US91826007P | 2007-03-15 | 2007-03-15 | |
| US91812307P | 2007-03-15 | 2007-03-15 | |
| US91808607P | 2007-03-15 | 2007-03-15 | |
| US60/918,260 | 2007-03-15 | ||
| US60/918,086 | 2007-03-15 | ||
| US60/918,123 | 2007-03-15 | ||
| US60/918,261 | 2007-03-15 | ||
| US838607P | 2007-12-20 | 2007-12-20 | |
| US838507P | 2007-12-20 | 2007-12-20 | |
| US837007P | 2007-12-20 | 2007-12-20 | |
| US61/008,386 | 2007-12-20 | ||
| US61/008,370 | 2007-12-20 | ||
| US61/008,385 | 2007-12-20 | ||
| US1067208P | 2008-01-10 | 2008-01-10 | |
| US61/010,672 | 2008-01-10 | ||
| PCT/US2008/003175 WO2008112205A1 (en) | 2007-03-09 | 2008-03-07 | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2680275A1 CA2680275A1 (en) | 2008-09-18 |
| CA2680275C true CA2680275C (en) | 2016-08-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2680275A Expired - Fee Related CA2680275C (en) | 2007-03-09 | 2008-03-07 | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8093265B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2124562B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010520875A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101686680B (cg-RX-API-DMAC7.html) |
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| WO (1) | WO2008112205A1 (cg-RX-API-DMAC7.html) |
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| BRPI0709596A2 (pt) | 2006-03-16 | 2011-07-19 | Renovis Inc | compostos bicicloeteroarila como moduladores de p2x7 e seus usos |
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| CA2645556C (en) | 2006-03-16 | 2016-05-24 | Renovis, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
| BRPI0714062A2 (pt) * | 2006-07-06 | 2012-12-18 | Glaxo Group Ltd | n-fenil-metil-5-oxo-prolina-2-amidas substituìdas como antagonistas do receptor da p2x, e os seus métodos de uso |
| US8212723B2 (en) * | 2008-08-27 | 2012-07-03 | Qualcomm Incorporated | Method and apparatus for determining at a predetermined granularity the direction and range of a transmitting mobile device |
| RU2014106611A (ru) * | 2011-07-22 | 2015-08-27 | Актелион Фармасьютиклз Лтд | Производные гетероциклических амидов в качестве антагонистов р2х7 рецептора |
| HK1203932A1 (en) | 2012-01-20 | 2015-11-06 | Actelion Pharmaceuticals Ltd. | Heterocyclic amide derivatives as p2x7 receptor antagonists |
| WO2014091415A1 (en) | 2012-12-12 | 2014-06-19 | Actelion Pharmaceuticals Ltd | Indole carboxamide derivatives as p2x7 receptor antagonists |
| AR094053A1 (es) | 2012-12-18 | 2015-07-08 | Actelion Pharmaceuticals Ltd | Derivados de indol carboxamida como antagonistas del receptor p2x₇ |
| US9388197B2 (en) | 2013-01-22 | 2016-07-12 | Actelion Pharmaceuticals Ltd. | Heterocyclic amide derivatives as P2X7 receptor antagonists |
| WO2014115078A1 (en) | 2013-01-22 | 2014-07-31 | Actelion Pharmaceuticals Ltd | Heterocyclic amide derivatives as p2x7 receptor antagonists |
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| TWI825637B (zh) | 2021-03-31 | 2023-12-11 | 美商輝瑞股份有限公司 | 啶－１，６（２ｈ，７ｈ）－二酮 |
| WO2025057074A1 (en) * | 2023-09-13 | 2025-03-20 | Suven Life Sciences Limited | N-aryl benzamide derivatives as p2x7 receptor antagonists |
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| US8093265B2 (en) | 2012-01-10 |
| EP2124562A4 (en) | 2010-03-10 |
| CA2680275A1 (en) | 2008-09-18 |
| WO2008112205A1 (en) | 2008-09-18 |
| HK1136967A1 (zh) | 2010-07-16 |
| DK2124562T3 (en) | 2016-08-01 |
| CN101686680A (zh) | 2010-03-31 |
| US20080287415A1 (en) | 2008-11-20 |
| JP2010520875A (ja) | 2010-06-17 |
| CN101686680B (zh) | 2015-12-09 |
| ES2576643T3 (es) | 2016-07-08 |
| EP2124562B1 (en) | 2016-04-20 |
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