CA2372796A1 - Cuve de reaction contenant un tube siphon - Google Patents

Cuve de reaction contenant un tube siphon Download PDF

Info

Publication number
CA2372796A1
CA2372796A1 CA002372796A CA2372796A CA2372796A1 CA 2372796 A1 CA2372796 A1 CA 2372796A1 CA 002372796 A CA002372796 A CA 002372796A CA 2372796 A CA2372796 A CA 2372796A CA 2372796 A1 CA2372796 A1 CA 2372796A1
Authority
CA
Canada
Prior art keywords
reaction vessel
riser
reaction
housing
vessel according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002372796A
Other languages
English (en)
Inventor
Johann Schwartz
Heinz Stadtmuller
Walter Hudler
Wolfgang Jorg
Martin Schmidt
Gerhard Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2372796A1 publication Critical patent/CA2372796A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B01J2219/00283—Reactor vessels with top opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B01J2219/00286—Reactor vessels with top and bottom openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00423—Means for dispensing and evacuation of reagents using filtration, e.g. through porous frits
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)

Abstract

L'invention concerne un réacteur (1) pouvant être utilisé pour réaliser des synthèses en phase solide dans un bloc de réaction, le liquide de réaction (2) pouvant être acheminé par l'intermédiaire d'une évacuation de siphon d'une plaque de microtitration. Selon l'invention, un tube siphon (16) est placé au niveau de l'évacuation (15) du réacteur, et un tube ascendant (21) est placé à une distance radiale dudit tube siphon (16). Ce tube ascendant (21) est fermé au niveau de sa partie supérieure et relié au tube siphon (16). Il communique au niveau de la zone inférieure du réacteur avec une zone de réception (12) de ce dernier. Cette conception permet d'éviter d'avoir recours à un usinage supplémentaire pour former l'évacuation de siphon et empêche l'apparition de pratiquement tout défaut d'étanchéité dans la zone de l'évacuation de siphon.
CA002372796A 1999-04-08 2000-04-04 Cuve de reaction contenant un tube siphon Abandoned CA2372796A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1999115811 DE19915811C2 (de) 1999-04-08 1999-04-08 Reaktionsgefäß
DE19915811.8 1999-04-08
PCT/EP2000/002988 WO2000061279A1 (fr) 1999-04-08 2000-04-04 Reacteur contenant un tube siphon

Publications (1)

Publication Number Publication Date
CA2372796A1 true CA2372796A1 (fr) 2000-10-19

Family

ID=7903862

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002372796A Abandoned CA2372796A1 (fr) 1999-04-08 2000-04-04 Cuve de reaction contenant un tube siphon

Country Status (7)

Country Link
EP (1) EP1183098A1 (fr)
JP (1) JP2002540931A (fr)
AU (1) AU3558800A (fr)
CA (1) CA2372796A1 (fr)
DE (1) DE19915811C2 (fr)
MX (1) MXPA01010014A (fr)
WO (1) WO2000061279A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10057195A1 (de) * 2000-11-17 2002-05-23 Robert Loesel Reaktionsgefäß mit Membranboden
EP1291075B1 (fr) * 2001-09-07 2007-04-11 F. Hoffmann-La Roche Ag Bloc de réaction pour la chimie de synthèse en parallèle et récipient pour cela
EP1291074A1 (fr) * 2001-09-07 2003-03-12 F. Hoffmann-La Roche Ag Bloc de réaction pour la chimie de synthèse en parallèle et récipient pour cela

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE940110L (en) * 1989-03-23 1990-09-23 Bunce Roger A Liquid transfer devices
US5516491A (en) * 1994-07-28 1996-05-14 Merck & Co., Inc. Disposable reactor vessel
SE503529C2 (sv) * 1994-10-17 1996-07-01 System Teeg Ab Handfatsventil med integrerat vattenlås
US5609826A (en) * 1995-04-17 1997-03-11 Ontogen Corporation Methods and apparatus for the generation of chemical libraries
US5746982A (en) * 1996-02-29 1998-05-05 Advanced Chemtech, Inc. Apparatus for automated synthesis of chemical compounds
AU2939497A (en) * 1996-05-10 1998-01-05 Alanex Corporation Simultaneous chemical reaction apparatus

Also Published As

Publication number Publication date
WO2000061279A1 (fr) 2000-10-19
AU3558800A (en) 2000-11-14
EP1183098A1 (fr) 2002-03-06
DE19915811A1 (de) 2000-10-19
DE19915811C2 (de) 2001-05-03
JP2002540931A (ja) 2002-12-03
MXPA01010014A (es) 2002-04-24

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Legal Events

Date Code Title Description
FZDE Discontinued