CA2339174C - Aminosterol compounds and uses thereof - Google Patents
Aminosterol compounds and uses thereof Download PDFInfo
- Publication number
- CA2339174C CA2339174C CA002339174A CA2339174A CA2339174C CA 2339174 C CA2339174 C CA 2339174C CA 002339174 A CA002339174 A CA 002339174A CA 2339174 A CA2339174 A CA 2339174A CA 2339174 C CA2339174 C CA 2339174C
- Authority
- CA
- Canada
- Prior art keywords
- aminosterol
- compound
- compounds
- aminosterols
- protons
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9633798P | 1998-08-12 | 1998-08-12 | |
| US60/096,337 | 1998-08-12 | ||
| PCT/US1999/018322 WO2000009137A2 (en) | 1998-08-12 | 1999-08-12 | Aminosterol compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2339174A1 CA2339174A1 (en) | 2000-02-24 |
| CA2339174C true CA2339174C (en) | 2009-01-06 |
Family
ID=22256894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002339174A Expired - Fee Related CA2339174C (en) | 1998-08-12 | 1999-08-12 | Aminosterol compounds and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6388108B1 (enExample) |
| EP (1) | EP1105407B1 (enExample) |
| JP (1) | JP2002522501A (enExample) |
| AT (1) | ATE375359T1 (enExample) |
| AU (1) | AU773038B2 (enExample) |
| CA (1) | CA2339174C (enExample) |
| DE (1) | DE69937301T2 (enExample) |
| WO (1) | WO2000009137A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5847172A (en) * | 1995-06-07 | 1998-12-08 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| MXPA03008085A (es) * | 2001-03-21 | 2004-03-10 | Leo Pharma As | Derivados de acido fusidico poliaminados novedosos. |
| CN100491392C (zh) * | 2002-04-05 | 2009-05-27 | 利奥制药有限公司 | 支链多胺甾体衍生物 |
| US20070129690A1 (en) | 2005-12-02 | 2007-06-07 | Joel Rosenblatt | Catheter with polymeric coating |
| WO2008038965A1 (en) * | 2006-09-26 | 2008-04-03 | Kyungpook National University Industry-Academic Cooperation Foundation | 7alpha-aminosteroid derivatives or pharmaceutically acceptable salts thereof, preparation method thereof and composition for anticancer or antibiotics containing the same as an active ingredient |
| CN101600429A (zh) * | 2006-12-08 | 2009-12-09 | 哈多技术有限公司 | 治疗和预防传染性疾病的胆固醇胺 |
| US20080188830A1 (en) * | 2007-02-06 | 2008-08-07 | Arrow International, Inc. | Selectively reinforced medical devices |
| WO2009032321A2 (en) * | 2007-09-06 | 2009-03-12 | Genaera Corporation | A method for treating diabetes |
| CA2711807A1 (en) | 2008-01-08 | 2009-07-16 | Akthelia Pharmaceuticals | Agonists for antimicrobial peptide systems |
| WO2009090063A1 (en) * | 2008-01-16 | 2009-07-23 | Jado Technologies Gmbh | Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases |
| WO2010039828A1 (en) * | 2008-10-01 | 2010-04-08 | Teleflex Medical Incorporated | Article containing segregated biguanide and lewis acid |
| WO2011056650A2 (en) | 2009-10-27 | 2011-05-12 | Michael Zasloff | Methods and compositions for treating and preventing viral infections |
| US8623416B2 (en) * | 2009-11-25 | 2014-01-07 | Michael Zasloff | Formulations comprising aminosterols |
| US10040817B2 (en) | 2013-10-03 | 2018-08-07 | Enterin Laboratories, Inc. | Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same |
| MX356006B (es) * | 2013-10-18 | 2018-04-24 | Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C | Proceso para obtener una molécula que sirve como elicitor de péptidos antimicrobianos. |
| EP3515450A4 (en) * | 2016-09-21 | 2020-07-29 | Mount Desert Island Biological Laboratory | METHOD AND COMPOSITIONS FOR STIMULATING AND REINFORCING TISSUE REGENERATION |
| US11083735B2 (en) | 2017-09-08 | 2021-08-10 | Enterin, Inc. | Methods for treating sleep disorders, sleep disturbances, and related symptoms using aminosterol compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192756A (en) * | 1992-03-18 | 1993-03-09 | The Children's Hospital Of Pennsylvania | Aminosterol antibiotic |
| ATE169930T1 (de) | 1993-03-10 | 1998-09-15 | Magainin Pharma | Steroidderivate, pharmazeutische zusammensetzungen die sie enthalten und ihre verwendung als antibiotika oder desinfektionsmittel |
| US5840936A (en) * | 1995-06-07 | 1998-11-24 | Magainin Pharmaceuticals Inc. | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE) |
| US5763430A (en) | 1995-06-07 | 1998-06-09 | Magainin Pharmaceuticals Inc. | Method of treating a viral infection by administering a steroid compound |
| US5737691A (en) * | 1995-07-14 | 1998-04-07 | Motorola, Inc. | System and method for allocating frequency channels in a two-way messaging network |
| DK0910382T3 (da) * | 1996-04-26 | 2003-10-06 | Genaera Corp | Squalamin i kombination med andre anticancermidler til behandling af tumorer |
| US6262283B1 (en) * | 1996-12-06 | 2001-07-17 | Magainin Pharmaceuticals Inc. | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds |
-
1999
- 1999-08-12 EP EP99942130A patent/EP1105407B1/en not_active Expired - Lifetime
- 1999-08-12 CA CA002339174A patent/CA2339174C/en not_active Expired - Fee Related
- 1999-08-12 US US09/762,999 patent/US6388108B1/en not_active Expired - Fee Related
- 1999-08-12 DE DE69937301T patent/DE69937301T2/de not_active Expired - Lifetime
- 1999-08-12 JP JP2000564639A patent/JP2002522501A/ja active Pending
- 1999-08-12 AT AT99942130T patent/ATE375359T1/de not_active IP Right Cessation
- 1999-08-12 AU AU55575/99A patent/AU773038B2/en not_active Ceased
- 1999-08-12 WO PCT/US1999/018322 patent/WO2000009137A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000009137A3 (en) | 2000-05-18 |
| DE69937301T2 (de) | 2008-08-14 |
| WO2000009137A2 (en) | 2000-02-24 |
| JP2002522501A (ja) | 2002-07-23 |
| US6388108B1 (en) | 2002-05-14 |
| EP1105407A4 (en) | 2004-03-17 |
| ATE375359T1 (de) | 2007-10-15 |
| EP1105407B1 (en) | 2007-10-10 |
| CA2339174A1 (en) | 2000-02-24 |
| EP1105407A2 (en) | 2001-06-13 |
| DE69937301D1 (de) | 2007-11-22 |
| AU773038B2 (en) | 2004-05-13 |
| AU5557599A (en) | 2000-03-06 |
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