JP2002522501A - アミノステロール化合物類およびそれらの用途 - Google Patents

アミノステロール化合物類およびそれらの用途

Info

Publication number
JP2002522501A
JP2002522501A JP2000564639A JP2000564639A JP2002522501A JP 2002522501 A JP2002522501 A JP 2002522501A JP 2000564639 A JP2000564639 A JP 2000564639A JP 2000564639 A JP2000564639 A JP 2000564639A JP 2002522501 A JP2002522501 A JP 2002522501A
Authority
JP
Japan
Prior art keywords
aminosterol
compound
pharmaceutically acceptable
compound according
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000564639A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002522501A5 (enExample
Inventor
ミーナ ラオ，
ビンヤミン フェイブッシュ，
ウィリアム キンニー，
マイケル ザスロフ，
リンカーン ノーカー，
Original Assignee
ジェネーラ・コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネーラ・コーポレーション filed Critical ジェネーラ・コーポレーション
Publication of JP2002522501A publication Critical patent/JP2002522501A/ja
Publication of JP2002522501A5 publication Critical patent/JP2002522501A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2000564639A 1998-08-12 1999-08-12 アミノステロール化合物類およびそれらの用途 Pending JP2002522501A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9633798P 1998-08-12 1998-08-12
US60/096,337 1998-08-12
PCT/US1999/018322 WO2000009137A2 (en) 1998-08-12 1999-08-12 Aminosterol compounds and uses thereof

Publications (2)

Publication Number Publication Date
JP2002522501A true JP2002522501A (ja) 2002-07-23
JP2002522501A5 JP2002522501A5 (enExample) 2006-09-28

Family

ID=22256894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000564639A Pending JP2002522501A (ja) 1998-08-12 1999-08-12 アミノステロール化合物類およびそれらの用途

Country Status (8)

Country Link
US (1) US6388108B1 (enExample)
EP (1) EP1105407B1 (enExample)
JP (1) JP2002522501A (enExample)
AT (1) ATE375359T1 (enExample)
AU (1) AU773038B2 (enExample)
CA (1) CA2339174C (enExample)
DE (1) DE69937301T2 (enExample)
WO (1) WO2000009137A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
IL157578A0 (en) * 2001-03-21 2004-03-28 Leo Pharma As Novel fusidic derivatives
KR20040097287A (ko) * 2002-04-05 2004-11-17 레오 파마 에이/에스 분지된 폴리아민 스테로이드 유도체
US20070129690A1 (en) 2005-12-02 2007-06-07 Joel Rosenblatt Catheter with polymeric coating
WO2008038965A1 (en) * 2006-09-26 2008-04-03 Kyungpook National University Industry-Academic Cooperation Foundation 7alpha-aminosteroid derivatives or pharmaceutically acceptable salts thereof, preparation method thereof and composition for anticancer or antibiotics containing the same as an active ingredient
AU2007327761A1 (en) * 2006-12-08 2008-06-12 Jado Technologies Gmbh Cholesterylamines for the treatment and prevention of infectious diseases
US20080188830A1 (en) * 2007-02-06 2008-08-07 Arrow International, Inc. Selectively reinforced medical devices
CA2985271A1 (en) * 2007-09-06 2009-03-12 Ohr Pharmaceutical, Inc. A method for treating diabetes
US9078864B2 (en) 2008-01-08 2015-07-14 Akthelia Pharmaceuticals Agonists for antimicrobial peptide systems
WO2009090063A1 (en) * 2008-01-16 2009-07-23 Jado Technologies Gmbh Steroid sapogenin, androstane and triterpenoid sapogenin derivatives for the treatment and prevention of infectious diseases
US20100082097A1 (en) * 2008-10-01 2010-04-01 Joel Rosenblatt Article Containing Segregated Biguanide and Lewis Acid
WO2011056650A2 (en) 2009-10-27 2011-05-12 Michael Zasloff Methods and compositions for treating and preventing viral infections
WO2011066260A2 (en) * 2009-11-25 2011-06-03 Michael Zasloff Formulations comprising aminosterols
US10040817B2 (en) 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
MX356006B (es) * 2013-10-18 2018-04-24 Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C Proceso para obtener una molécula que sirve como elicitor de péptidos antimicrobianos.
CA3037712A1 (en) * 2016-09-21 2018-03-29 Mount Desert Island Biological Laboratory Methods and compositions for stimulation and enhancement of regeneration of tissues
EP3678671A4 (en) 2017-09-08 2022-12-07 Enterin, Inc. METHODS OF TREATMENT OF SLEEPING DISEASES, SLEEP DISORDERS AND RELATED SYMPTOMS USING AMINOSTEROL COMPOSITIONS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192756A (en) * 1992-03-18 1993-03-09 The Children's Hospital Of Pennsylvania Aminosterol antibiotic
US5637691A (en) * 1993-03-10 1997-06-10 Magainin Pharmaceuticals, Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840936A (en) 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5737691A (en) * 1995-07-14 1998-04-07 Motorola, Inc. System and method for allocating frequency channels in a two-way messaging network
PT910382E (pt) * 1996-04-26 2003-10-31 Genaera Corp Esqualamina em combinacao com outros agentes anti-cancro para o tratamento de tumores
US6262283B1 (en) * 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192756A (en) * 1992-03-18 1993-03-09 The Children's Hospital Of Pennsylvania Aminosterol antibiotic
US5637691A (en) * 1993-03-10 1997-06-10 Magainin Pharmaceuticals, Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5721226A (en) * 1993-03-10 1998-02-24 Magainin Pharmaceuticals Inc. Method for inhibiting angiogenesis using squalamine and squalamine steroid derivatives
US5733899A (en) * 1993-03-10 1998-03-31 Magainin Pharmaceuticals Inc. Method for treating infection using steroid based pharmaceutical compositions
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound

Also Published As

Publication number Publication date
ATE375359T1 (de) 2007-10-15
DE69937301T2 (de) 2008-08-14
EP1105407B1 (en) 2007-10-10
EP1105407A2 (en) 2001-06-13
US6388108B1 (en) 2002-05-14
DE69937301D1 (de) 2007-11-22
CA2339174C (en) 2009-01-06
EP1105407A4 (en) 2004-03-17
CA2339174A1 (en) 2000-02-24
WO2000009137A2 (en) 2000-02-24
WO2000009137A3 (en) 2000-05-18
AU5557599A (en) 2000-03-06
AU773038B2 (en) 2004-05-13

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