CA2274149C - Peptides and compounds that bind to a receptor - Google Patents
Peptides and compounds that bind to a receptor Download PDFInfo
- Publication number
- CA2274149C CA2274149C CA002274149A CA2274149A CA2274149C CA 2274149 C CA2274149 C CA 2274149C CA 002274149 A CA002274149 A CA 002274149A CA 2274149 A CA2274149 A CA 2274149A CA 2274149 C CA2274149 C CA 2274149C
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- seq
- peptide
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CA002621857A CA2621857A1 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US08/764640 | 1996-12-11 | ||
US08/764,640 US5869451A (en) | 1995-06-07 | 1996-12-11 | Peptides and compounds that bind to a receptor |
PCT/EP1997/006850 WO1998025965A2 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to the thrombopoietin receptor |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA002621857A Division CA2621857A1 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Publications (2)
Publication Number | Publication Date |
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CA2274149A1 CA2274149A1 (en) | 1998-06-18 |
CA2274149C true CA2274149C (en) | 2008-07-15 |
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Application Number | Title | Priority Date | Filing Date |
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CA002274149A Expired - Lifetime CA2274149C (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Country Status (24)
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US (2) | US5869451A (en, 2012) |
EP (3) | EP2028191A1 (en, 2012) |
JP (1) | JP4128225B2 (en, 2012) |
KR (3) | KR100679576B1 (en, 2012) |
CN (1) | CN100379760C (en, 2012) |
AR (2) | AR010752A1 (en, 2012) |
AT (1) | ATE420893T1 (en, 2012) |
AU (1) | AU725731B2 (en, 2012) |
BR (1) | BRPI9713914B1 (en, 2012) |
CA (1) | CA2274149C (en, 2012) |
CO (1) | CO5080768A1 (en, 2012) |
DE (1) | DE69739219D1 (en, 2012) |
ES (1) | ES2321038T3 (en, 2012) |
HR (1) | HRP970683B1 (en, 2012) |
MA (1) | MA26454A1 (en, 2012) |
PA (1) | PA8442601A1 (en, 2012) |
PE (1) | PE27599A1 (en, 2012) |
SV (1) | SV1997000104A (en, 2012) |
TN (1) | TNSN97201A1 (en, 2012) |
TR (2) | TR199901971T2 (en, 2012) |
TW (1) | TW515804B (en, 2012) |
UY (1) | UY24805A1 (en, 2012) |
WO (1) | WO1998025965A2 (en, 2012) |
ZA (1) | ZA9711045B (en, 2012) |
Families Citing this family (122)
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US5869451A (en) * | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
CN1315870C (zh) * | 1995-06-07 | 2007-05-16 | 葛兰素集团有限公司 | 结合血小板生成素受体的肽和化合物 |
US6251864B1 (en) | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
US7083983B2 (en) * | 1996-07-05 | 2006-08-01 | Cancer Research Campaign Technology Limited | Inhibitors of the interaction between P53 and MDM2 |
ES2284217T3 (es) | 1997-10-31 | 2007-11-01 | Smithkline Beecham Corporation | Complejos metalicos novedosos. |
DE69839191T2 (de) | 1997-10-31 | 2009-02-19 | Smithkline Beecham Corp. | Metall-komplexe mit antibakteriele und fungizide wirkungen |
JP2001521897A (ja) * | 1997-10-31 | 2001-11-13 | スミスクライン・ビーチャム・コーポレイション | 新規な金属錯体 |
US7153655B2 (en) | 1998-06-16 | 2006-12-26 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence |
US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
US7488590B2 (en) * | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
HK1042114B (zh) * | 1998-10-23 | 2006-09-29 | Amgen K-A, Inc. | 与mp1受体结合并具有血小板生成活性的模拟二聚体血小板生成素肽 |
CA2382547A1 (en) * | 1999-09-21 | 2001-03-29 | Stephen R. Hanson | Methods and compositions for treating platelet-related disosders |
US20030190644A1 (en) | 1999-10-13 | 2003-10-09 | Andreas Braun | Methods for generating databases and databases for identifying polymorphic genetic markers |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
AU784746B2 (en) | 1999-11-18 | 2006-06-08 | Dendreon Corporation | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
US7700341B2 (en) | 2000-02-03 | 2010-04-20 | Dendreon Corporation | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
AU5943201A (en) * | 2000-05-03 | 2001-11-12 | Amgen Inc | Modified peptides as therapeutic agents |
US20050158838A1 (en) * | 2000-06-19 | 2005-07-21 | Dyax Corp., A Delaware Corporation | Novel enterokinase cleavage sequences |
US20040253242A1 (en) * | 2000-12-05 | 2004-12-16 | Bowdish Katherine S. | Rationally designed antibodies |
US7396917B2 (en) * | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
ATE414720T1 (de) * | 2000-12-05 | 2008-12-15 | Alexion Pharma Inc | Rationell entworfene antikörper |
US6958213B2 (en) | 2000-12-12 | 2005-10-25 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function |
AU2002305052A1 (en) | 2001-03-13 | 2002-09-24 | Corvas International, Inc. | Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon |
KR20040011480A (ko) | 2001-03-22 | 2004-02-05 | 덴드레온 샌 디에고 엘엘씨 | 세린 프로테아제 cvsp14를 암호화하는 핵산 분자,암호화된 폴리펩티드 및 이에 근거한 방법 |
KR20030096292A (ko) | 2001-03-27 | 2003-12-24 | 덴드레온 샌 디에고 엘엘씨 | 트랜스막 세린 프로테아제 9를 암호화하는 핵산 분자,암호화된 폴리펩티드 및 이에 근거한 방법 |
CA2447050A1 (en) | 2001-05-14 | 2002-11-21 | Dendreon San Diego Llc | Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon |
US7332474B2 (en) * | 2001-10-11 | 2008-02-19 | Amgen Inc. | Peptides and related compounds having thrombopoietic activity |
WO2003044179A2 (en) * | 2001-11-20 | 2003-05-30 | Dendreon San Diego Llc | Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon |
US20030191056A1 (en) | 2002-04-04 | 2003-10-09 | Kenneth Walker | Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins |
US7432342B2 (en) | 2002-05-03 | 2008-10-07 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof and related documents |
US7262012B2 (en) | 2002-05-17 | 2007-08-28 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations |
ATE312605T1 (de) * | 2002-06-29 | 2005-12-15 | Aquanova Ger Solubilisate Tech | Isoflavonkonzentrate sowie verfahren zu ihrer herstellung |
US20040028661A1 (en) * | 2002-08-07 | 2004-02-12 | Bartelmez Stephen H. | Expansion of cells using thrombopoietin and anti-transforming growth factor-beta |
US7851503B2 (en) | 2002-08-14 | 2010-12-14 | Nissan Chemical Industries, Ltd. | Thrombopoetin receptor activator and process for producing the same |
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