CA2274149C - Peptides and compounds that bind to a receptor - Google Patents
Peptides and compounds that bind to a receptor Download PDFInfo
- Publication number
- CA2274149C CA2274149C CA002274149A CA2274149A CA2274149C CA 2274149 C CA2274149 C CA 2274149C CA 002274149 A CA002274149 A CA 002274149A CA 2274149 A CA2274149 A CA 2274149A CA 2274149 C CA2274149 C CA 2274149C
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- seq
- peptide
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002621857A CA2621857A1 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/764640 | 1996-12-11 | ||
| US08/764,640 US5869451A (en) | 1995-06-07 | 1996-12-11 | Peptides and compounds that bind to a receptor |
| PCT/EP1997/006850 WO1998025965A2 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to the thrombopoietin receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002621857A Division CA2621857A1 (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2274149A1 CA2274149A1 (en) | 1998-06-18 |
| CA2274149C true CA2274149C (en) | 2008-07-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002274149A Expired - Lifetime CA2274149C (en) | 1996-12-11 | 1997-12-09 | Peptides and compounds that bind to a receptor |
Country Status (24)
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|---|---|
| US (2) | US5869451A (OSRAM) |
| EP (3) | EP0948539B1 (OSRAM) |
| JP (1) | JP4128225B2 (OSRAM) |
| KR (3) | KR100625708B1 (OSRAM) |
| CN (1) | CN100379760C (OSRAM) |
| AR (2) | AR010752A1 (OSRAM) |
| AT (1) | ATE420893T1 (OSRAM) |
| AU (1) | AU725731B2 (OSRAM) |
| BR (1) | BRPI9713914B1 (OSRAM) |
| CA (1) | CA2274149C (OSRAM) |
| CO (1) | CO5080768A1 (OSRAM) |
| DE (1) | DE69739219D1 (OSRAM) |
| ES (1) | ES2321038T3 (OSRAM) |
| HR (1) | HRP970683B1 (OSRAM) |
| MA (1) | MA26454A1 (OSRAM) |
| PA (1) | PA8442601A1 (OSRAM) |
| PE (1) | PE27599A1 (OSRAM) |
| SV (1) | SV1997000104A (OSRAM) |
| TN (1) | TNSN97201A1 (OSRAM) |
| TR (2) | TR200401638T2 (OSRAM) |
| TW (1) | TW515804B (OSRAM) |
| UY (1) | UY24805A1 (OSRAM) |
| WO (1) | WO1998025965A2 (OSRAM) |
| ZA (1) | ZA9711045B (OSRAM) |
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| US5869451A (en) * | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US6251864B1 (en) | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| EP2055712A1 (en) * | 1995-06-07 | 2009-05-06 | Glaxo Group Limited | Peptides and compounds that bind to a thrombopoietin receptor |
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| US7083983B2 (en) * | 1996-07-05 | 2006-08-01 | Cancer Research Campaign Technology Limited | Inhibitors of the interaction between P53 and MDM2 |
| US20010016568A1 (en) | 1997-10-31 | 2001-08-23 | Juan I. Luengo | Novel metal complexes |
| ES2301215T3 (es) | 1997-10-31 | 2008-06-16 | Smithkline Beecham Corporation | Complejos de metal con efectos antibacterianos y fungicidas. |
| AU739173B2 (en) * | 1997-10-31 | 2001-10-04 | Ligand Pharmaceuticals Incorporated | Novel metal complexes |
| US7153655B2 (en) | 1998-06-16 | 2006-12-26 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence |
| US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
| WO2000024770A2 (en) | 1998-10-23 | 2000-05-04 | Amgen Inc. | Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity |
| US6660843B1 (en) * | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US6376242B1 (en) * | 1999-09-21 | 2002-04-23 | Emory University | Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents |
| US7668658B2 (en) | 1999-10-13 | 2010-02-23 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| EP1230349B1 (en) | 1999-11-18 | 2007-06-13 | Dendreon Corporation | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
| TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
| US7700341B2 (en) | 2000-02-03 | 2010-04-20 | Dendreon Corporation | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
| AU5943201A (en) * | 2000-05-03 | 2001-11-12 | Amgen Inc | Modified peptides as therapeutic agents |
| US20050158838A1 (en) * | 2000-06-19 | 2005-07-21 | Dyax Corp., A Delaware Corporation | Novel enterokinase cleavage sequences |
| US7396917B2 (en) | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
| DE60136656D1 (de) * | 2000-12-05 | 2009-01-02 | Alexion Pharma Inc | Rationell entworfene Antikörper |
| US20040253242A1 (en) * | 2000-12-05 | 2004-12-16 | Bowdish Katherine S. | Rationally designed antibodies |
| US6958213B2 (en) | 2000-12-12 | 2005-10-25 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function |
| WO2002072786A2 (en) | 2001-03-13 | 2002-09-19 | Corvas International, Inc. | Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon |
| JP2004535166A (ja) | 2001-03-22 | 2004-11-25 | デンドレオン・サンディエゴ・リミテッド・ライアビリティ・カンパニー | セリンプロテアーゼｃｖｓｐ１４をコードする核酸分子、コードされるポリペプチドおよびそれに基づく方法 |
| US7105333B2 (en) | 2001-03-27 | 2006-09-12 | Deadreon Corporation | Nucleic acid molecules encoding a transmembrane serine protease 9, the encoded polypeptides and methods based thereon |
| KR20040080940A (ko) | 2001-05-14 | 2004-09-20 | 덴드레온 코포레이션 | 트랜스막 세린 프로테아제 10을 암호화하는 핵산 분자,암호화된 폴리펩티드 및 이에 근거한 방법 |
| US7332474B2 (en) * | 2001-10-11 | 2008-02-19 | Amgen Inc. | Peptides and related compounds having thrombopoietic activity |
| WO2003044179A2 (en) * | 2001-11-20 | 2003-05-30 | Dendreon San Diego Llc | Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon |
| US20030191056A1 (en) | 2002-04-04 | 2003-10-09 | Kenneth Walker | Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins |
| CA2484676A1 (en) | 2002-05-03 | 2003-11-13 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof, and related methods |
| US7262012B2 (en) | 2002-05-17 | 2007-08-28 | Alligator Bioscience Ab | Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations |
| JP2005531616A (ja) * | 2002-06-29 | 2005-10-20 | アクヴァノヴァ・ジャーマン・ソリュービリセイト・テクノロジーズ・（アーゲーテー）・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | イソフラボン濃縮物およびその製造法 |
| US20040028661A1 (en) * | 2002-08-07 | 2004-02-12 | Bartelmez Stephen H. | Expansion of cells using thrombopoietin and anti-transforming growth factor-beta |
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