CA2251262C - Nucleic acid encoding a nervous tissue sodium channel - Google Patents

Nucleic acid encoding a nervous tissue sodium channel Download PDF

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Publication number
CA2251262C
CA2251262C CA002251262A CA2251262A CA2251262C CA 2251262 C CA2251262 C CA 2251262C CA 002251262 A CA002251262 A CA 002251262A CA 2251262 A CA2251262 A CA 2251262A CA 2251262 C CA2251262 C CA 2251262C
Authority
CA
Canada
Prior art keywords
dna
leu
sodium channel
phe
ile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002251262A
Other languages
English (en)
French (fr)
Other versions
CA2251262A1 (en
Inventor
Paul Shartzer Dietrich
Linda Marie Fish
Reena Khare
Douglas Kenneth Rabert
Lakshmi Sangameswaran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2251262A1 publication Critical patent/CA2251262A1/en
Application granted granted Critical
Publication of CA2251262C publication Critical patent/CA2251262C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
CA002251262A 1997-11-20 1998-11-18 Nucleic acid encoding a nervous tissue sodium channel Expired - Fee Related CA2251262C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6622597P 1997-11-20 1997-11-20
US60/066,225 1997-11-20

Publications (2)

Publication Number Publication Date
CA2251262A1 CA2251262A1 (en) 1999-05-20
CA2251262C true CA2251262C (en) 2003-03-25

Family

ID=22068111

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002251262A Expired - Fee Related CA2251262C (en) 1997-11-20 1998-11-18 Nucleic acid encoding a nervous tissue sodium channel

Country Status (13)

Country Link
JP (1) JPH11235186A (de)
AT (1) AT410672B (de)
AU (1) AU710551B2 (de)
BE (1) BE1014938A4 (de)
CA (1) CA2251262C (de)
CH (1) CH693031A5 (de)
DE (1) DE19853233C2 (de)
FR (1) FR2771103A1 (de)
GB (1) GB2332906B (de)
IE (1) IE980956A1 (de)
IT (1) IT1306213B1 (de)
NL (1) NL1010602C2 (de)
SE (1) SE9803962L (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038889A2 (en) * 1998-01-29 1999-08-05 Yale University Modulation of sodium channels in dorsal root ganglia
US6573067B1 (en) 1998-01-29 2003-06-03 Yale University Nucleic acid encoding sodium channels in dorsal root ganglia
EP1257646A2 (de) * 2000-02-25 2002-11-20 Incyte Genomics, Inc. Transporter und ionenkanäle
DE10022092A1 (de) 2000-05-08 2001-11-15 Aventis Behring Gmbh Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung
CA2410084A1 (en) * 2000-05-26 2001-12-06 Incyte Genomics, Inc. Transporters and ion channels
US7423121B2 (en) 2000-07-05 2008-09-09 Neurosearch A/S Sodium channel rNav1.5a
CA2417587A1 (en) * 2000-08-03 2002-02-14 Incyte Genomics, Inc. Transporters and ion channels
EP1485467A4 (de) * 2002-03-20 2006-05-10 Transmolecular Inc Rekombinante expressionsvektoren für funktionelle nav1.9-natriumkanäle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380836A (en) * 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
MX9703187A (es) * 1994-11-02 1998-02-28 Trophix Pharm Inc Canales de sodio especificos del sistema nervioso periferico, adn que codifica para mismos, cristalizacion, difraccion por rayos x, modelado molecular por computadora, diseño racional de farmacos seleccion de farmacos y metodos para la elaboracion y
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel

Also Published As

Publication number Publication date
GB2332906A (en) 1999-07-07
GB9825378D0 (en) 1999-01-13
GB2332906A8 (en) 1999-07-19
ATA194298A (de) 2002-11-15
DE19853233C2 (de) 2000-05-04
NL1010602C2 (nl) 2004-02-13
AT410672B (de) 2003-06-25
GB2332906B (en) 2002-11-20
IE980956A1 (en) 2000-11-01
SE9803962L (sv) 1999-05-21
NL1010602A1 (nl) 1999-05-25
FR2771103A1 (fr) 1999-05-21
IT1306213B1 (it) 2001-05-30
AU710551B2 (en) 1999-09-23
CA2251262A1 (en) 1999-05-20
AU9327298A (en) 1999-06-10
DE19853233A1 (de) 1999-07-29
JPH11235186A (ja) 1999-08-31
CH693031A5 (de) 2003-01-31
ITMI982507A1 (it) 1999-05-20
SE9803962D0 (sv) 1998-11-19
BE1014938A4 (fr) 2004-07-06

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