IT1306213B1 - Sequenza di acido nucleico che codifica per una proteina dei canalidel sodio, preferibilmente ttx-resistente. - Google Patents

Sequenza di acido nucleico che codifica per una proteina dei canalidel sodio, preferibilmente ttx-resistente.

Info

Publication number
IT1306213B1
IT1306213B1 IT1998MI002507A ITMI982507A IT1306213B1 IT 1306213 B1 IT1306213 B1 IT 1306213B1 IT 1998MI002507 A IT1998MI002507 A IT 1998MI002507A IT MI982507 A ITMI982507 A IT MI982507A IT 1306213 B1 IT1306213 B1 IT 1306213B1
Authority
IT
Italy
Prior art keywords
ttx
resistant
nucleic acid
acid sequence
sequence coding
Prior art date
Application number
IT1998MI002507A
Other languages
English (en)
Italian (it)
Inventor
Dietrich Paul Shartzer
Linda Marie Fish
Reena Khare
Douglas Kenneth Rabert
Lakshmi Sangameswaran
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ITMI982507A1 publication Critical patent/ITMI982507A1/it
Application granted granted Critical
Publication of IT1306213B1 publication Critical patent/IT1306213B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT1998MI002507A 1997-11-20 1998-11-19 Sequenza di acido nucleico che codifica per una proteina dei canalidel sodio, preferibilmente ttx-resistente. IT1306213B1 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6622597P 1997-11-20 1997-11-20

Publications (2)

Publication Number Publication Date
ITMI982507A1 ITMI982507A1 (it) 1999-05-20
IT1306213B1 true IT1306213B1 (it) 2001-05-30

Family

ID=22068111

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002507A IT1306213B1 (it) 1997-11-20 1998-11-19 Sequenza di acido nucleico che codifica per una proteina dei canalidel sodio, preferibilmente ttx-resistente.

Country Status (13)

Country Link
JP (1) JPH11235186A (de)
AT (1) AT410672B (de)
AU (1) AU710551B2 (de)
BE (1) BE1014938A4 (de)
CA (1) CA2251262C (de)
CH (1) CH693031A5 (de)
DE (1) DE19853233C2 (de)
FR (1) FR2771103A1 (de)
GB (1) GB2332906B (de)
IE (1) IE980956A1 (de)
IT (1) IT1306213B1 (de)
NL (1) NL1010602C2 (de)
SE (1) SE9803962L (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6573067B1 (en) 1998-01-29 2003-06-03 Yale University Nucleic acid encoding sodium channels in dorsal root ganglia
EP1053250A4 (de) * 1998-01-29 2003-04-09 Univ Yale Modulation von natriumkanälen in dorsalen spinalganglien
EP1257646A2 (de) * 2000-02-25 2002-11-20 Incyte Genomics, Inc. Transporter und ionenkanäle
DE10022092A1 (de) 2000-05-08 2001-11-15 Aventis Behring Gmbh Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung
EP1320548A2 (de) * 2000-05-26 2003-06-25 Incyte Genomics, Inc. Transporter und ionenkanäle
WO2002002608A2 (en) * 2000-07-05 2002-01-10 Neurosearch A/S NEW SODIUM CHANNEL (rNaV1.5a) AND USE THEREOF
US20040224911A1 (en) * 2000-08-03 2004-11-11 Henry Yue Transporters and ion channels
WO2003080570A2 (en) * 2002-03-20 2003-10-02 Transmolecular, Inc. Recombinant expression vectors for functional nav1.9 sodium channels

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380836A (en) * 1989-02-13 1995-01-10 Arch Development Corporation Nucleic acid encoding sodium channel protein
DK0789575T3 (da) * 1994-11-02 2009-01-12 Nps Pharma Inc Perifer-nerve-system-specifikke natriumkanaler, DNA kodende derfor, screening af lægemidler og fremgangsmåder til fremstilling og anvendelse deraf
GB9513180D0 (en) * 1995-06-28 1995-08-30 Univ London Ion channel

Also Published As

Publication number Publication date
DE19853233A1 (de) 1999-07-29
FR2771103A1 (fr) 1999-05-21
CH693031A5 (de) 2003-01-31
SE9803962D0 (sv) 1998-11-19
ITMI982507A1 (it) 1999-05-20
AT410672B (de) 2003-06-25
DE19853233C2 (de) 2000-05-04
GB2332906A8 (en) 1999-07-19
CA2251262A1 (en) 1999-05-20
GB2332906B (en) 2002-11-20
GB2332906A (en) 1999-07-07
AU710551B2 (en) 1999-09-23
NL1010602A1 (nl) 1999-05-25
SE9803962L (sv) 1999-05-21
BE1014938A4 (fr) 2004-07-06
JPH11235186A (ja) 1999-08-31
AU9327298A (en) 1999-06-10
NL1010602C2 (nl) 2004-02-13
ATA194298A (de) 2002-11-15
CA2251262C (en) 2003-03-25
GB9825378D0 (en) 1999-01-13
IE980956A1 (en) 2000-11-01

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